Age, increased left ventricular mass, and lower regional myocardial perfusion are related to greater extent of myocardial dyssynchrony in asymptomatic individuals: The multi-ethnic study of atherosclerosis

Circulation

Volumn 120, Issue 10, 2009, Pages 859-866

  Rosen, Boaz D ^a,c,d   Fernandes, Veronica R S ^a   Nasir, Khuram ^a   Helle Valle, Thomas ^a   Jerosch Herold, Michael ^e   Bluemke, David A ^a,b,f   Lima, Joao A C ^a,b,g  

^a Division of Cardiology   (United States)

^b Department of Radiology ^*  (United States)

^c JOHNS HOPKINS UNIVERSITY   (United States)

^d UNIVERSITY OF UTAH   (United States)

^e BRIGHAM AND WOMEN S HOSPITAL   (United States)

^f NATIONAL INSTITUTES OF HEALTH   (United States)

^g JOHNS HOPKINS HOSPITAL   (United States)

Author keywords

Aging; Dyssynchrony; Hypertrophy; Magnetic resonance imaging; Perfusion

Indexed keywords

ADULT; AGED; ARTICLE; ATHEROSCLEROSIS; CONTROLLED STUDY; DEMOGRAPHY; FEMALE; HEART LEFT VENTRICLE MASS; HEART MUSCLE PERFUSION; HUMAN; MAJOR CLINICAL STUDY; MALE; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; RISK FACTOR; SYSTOLIC BLOOD PRESSURE; AGE; CHEMICALLY INDUCED DISORDER; COHORT ANALYSIS; CORONARY ARTERY BLOOD FLOW; ELECTROCARDIOGRAPHY; ETHNOLOGY; HEART ARRHYTHMIA; HEART DISEASE; HEART LEFT VENTRICLE FUNCTION; HEART LEFT VENTRICLE HYPERTROPHY; HEART SCINTISCANNING; HYPEREMIA; MIDDLE AGED; PATHOPHYSIOLOGY; PROSPECTIVE STUDY; SEX DIFFERENCE; SYSTOLE; TIME;

ADENOSINE; DIAGNOSTIC AGENT;

ADENOSINE; AGE FACTORS; AGED; AGED, 80 AND OVER; ARRHYTHMIAS, CARDIAC; ATHEROSCLEROSIS; COHORT STUDIES; CORONARY CIRCULATION; ELECTROCARDIOGRAPHY; FEMALE; HEART DISEASES; HUMANS; HYPEREMIA; HYPERTROPHY, LEFT VENTRICULAR; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; MYOCARDIAL PERFUSION IMAGING; PROSPECTIVE STUDIES; SEX FACTORS; SYSTOLE; TIME FACTORS; VENTRICULAR FUNCTION, LEFT;

EID: 70349762937     PISSN: 00097322     EISSN: 15244539     Source Type: Journal    
DOI: 10.1161/CIRCULATIONAHA.108.787408     Document Type: Article

References (30)

1. Haldeman GA, Croft JB, Giles WH, Rashidee A. Hospitalization of patients with heart failure: National Hospital Discharge Survey, 1985 to 1995. Am Heart J. 1999;137:352-360.
2. Kannel WB, Belanger AJ. Epidemiology of heart failure. Am Heart J. 1991;121:951-957.
3. 3. Haider AW, Larson MG, Benjamin EJ, Levy D. Increased left ventricular mass and hypertrophy are associated with increased risk for sudden death. J Am. Coll Cardiol. 1998;32:1454-1459. (Pubitemid 28522409)
4. Koren MJ, Devereux RB, Casale PN, Savage DD, Laragh JH. Relation of left ventricular mass and geometry to morbidity and mortality in uncomplicated essential hypertension. Ann Intern Med. 1991;114:345-352.
5. 5. Rosen BD, Edvardsen T, Lai S, Castillo E, Pan. L, Jerosch-Herold M, Sinha S, Kronmal R, Amett D, Crouse JR III, Heckbert SR, Bluemke DA, Lima JA. Left ventricular concentric remodeling is associated with decreased global and regional systolic function: the Multi-Ethnic Study of Atherosclerosis. Circulation. 2005;112:984-991. (Pubitemid 41170266)
6. 6.GrinesCL,BashoreTM,BoudoulasH,OlsonS,ShaferP,WooleyCF. Functionalabnormalitiesinisolated,leftbundlebranchblock: theeffectofinterventricularasynchrony.Circulation.1989;79:845-853. (Pubitemid19100544)
7. Prinzen FW, Cheriex EC, Delhaas T, van Oosterhout MF, Arts T, Wellens HJ, Reneman RS. Asymmetric thickness of the left ventricular wall resulting from asynchronous electric activation: a study in dogs with ventricular pacing and in patients with left bundle branch block. Am Heart J. 1995;130:1045-1053.
8. 8. Bild DE, Bluemke DA, Burke GL, Detrano R, Diez Roux AV, Folsom AR, Greenland P, Jacob DR Jr, Kronmal R, Liu K, Nelson JC, O'Leary D, Saad MF, Shea S, Szklo M, Tracy RP. Multi-ethnic study of atherosclerosis: objectives and design. Am J Epidemiol. 2002;156:871-881. (Pubitemid 35215769)
9. 9. Natori S, Lai S, Finn JP, Gomes AS, Hundley WG, Jerosch-Herold M, Pearson G, Sinha S, Arai A, Lima JA, Bluemke DA. Cardiovascular function in Multi-Ethnic Study of Atherosclerosis: normal values by age, sex, and ethnicity. AJR Am J Roentgenol. 2006;186:S357-S365. (Pubitemid 46105405)
10. Osman NF, Prince JL. Visualizing myocardial function using HARP MRI. Phys Med Biol. 2000;45:1665-1682.
11. 11. Yu CM, Zhang Q, Fung JW, Chan HC, Chan YS, Yip GW, Kong SL, Lin H, Zhang Y, Sanderson JE. A novel tool to assess systolic asynchrony and identify responders of cardiac resynchronization therapy by tissue synchronization, imaging. J Am Coll Cardiol. 2005;45:677-684. (Pubitemid 40278965)
12. 12. Rosen BD, Lima JA, Nasir K, Edvardsen T, Folsom. AR, Lai S, Bluemke DA, Jerosch-Herold M. Lower myocardial perfusion reserve is associated with decreased, regional left ventricular function in asymptomatic participants of the Multi-Ethnic Study of Atherosclerosis. Circulation. 2006; 114:289-297. (Pubitemid 44297095)
13. 13. Kitzman DW, Gardin JM, Gottdiener JS, Arnold A, Boineau R, Aurigemma G, Marino EK, Lyles M, Cushman M, Enright PL; CHS Research Group. Importance of heart failure with preserved systolic function in patients > or = 65 years of age: Cardiovascular Health Study. Am J Cardiol. 2001;87:413-419. (Pubitemid 32149998)
14. 14. Gottdiener JS, Arnold AM, Aurigemma GP, Polak JF, Tracy RP, Kitzman DW, Gardin JM, Rutledge JE, Boineau RC. Predictors of congestive heart failure in the elderly: the Cardiovascular Health Study. J Am Coll Cardiol. 2000;35:1628-1637. (Pubitemid 30307510)
15. 15.GottdienerJS,McClellandRL,MarshallR,ShemanskiL,FurbergCD,KitzmanDW, CushmanM,PolakJ,GardinJM,GershBJ,AurigemmaGP,ManolioTA. Outcomeofcongestiveheartfailureinelderlypersons: influenceofleftventricularsystolicfunction:theCardiovascularHealthStudy. AnnInternMed.2002;137:631-639.(Pubitemid35176095)
16. Bhatia RS, Tu JV, Lee DS, Austin PC, Fang J, Haouzi A, Gong Y, Liu PP. Outcome of heart failure with preserved ejection fraction in a population-based study. N Engl J Med. 2006;355:260-269.
17. Kitzman. DW, Sheikh KH, Beere PA, Philips JL, Higgmbotham MB. Age-related alterations of Doppler left ventricular filling indexes in normal subjects are independent of left ventricular mass, heart rate, contractility and loading conditions. J Am Coll Cardiol. 1991;18: 1243-1250.
18. Zile MR, Baicu CF, Gaasch WH. Diastolic heart failure: abnormalities in active relaxation and passive stiffness of the left ventricle. N Engl J Med. 2004;350:1953-1959.
19. 19.YipG,WangM,ZhangY,FungJW,HoPY,Sanderson.JE. Leftventricularlongaxisfunctionindiastoli cheartfailureisreducedinbothdiastoleandsystole:timeforaredefinition?Heart. 2002;87:121-125.(Pubitemid34098370)
20. Borges MC, Colombo RC, Goncalves JG, Ferreira JO, Franchini KG. Longitudinal mitral annulus velocities are reduced in hypertensive subjects with or without left ventricle hypertrophy. Hypertension. 2006; 47:854-860.
21. 21. Wang J, Kurrelmeyer KM, Torre-Amione G, Nagueh SF. Systolic and diastolic dyssynchrony in patients with diastolic heart failure and the effect of medical therapy. J Am. Coll Cardiol. 2007;49:88-96. (Pubitemid 46026901)
22. Bonow RO, Vitale DF, Bacharach SL, Maron BJ, Green MV. Effects of aging on asynchronous left ventricular regional function and global ventricular filling in normal human subjects. J Am Coll Cardiol. 1988;11:50-58.
23. Fonseca CG, Oxenham HC, Cowan BR, Occleshaw CJ, Young AA. Aging alters patterns of regional nonuniformity in LV strain relaxation: a 3-D MR tissue tagging study. Am J Physiol. 2003;285:H621-H630.
24. 24. Skulstad H, Edvardsen T, Urheim S, Rabben SI, Stugaard M, Lyseggen E, Ihlen H, Smiseth OA. Postsystolic shortening in ischemic myocardium: active contraction or passive recoil? Circulation. 2002;106:718-724. (Pubitemid 34851932)
25. 25.LopezB,GonzalezA,QuerejetaR,DiezJ.Theuseofcollagen- derivedserumpeptidesfortheclinicalassessmentofhypertensiveheartdisease. JHypertens.2005;23:1445-1451.(Pubitemid41104811)
26. Aurigemma GP, Silver KH, Priest MA, Gaasch WH. Geometric changes allow normal ejection fraction despite depressed myocardial shortening in hypertensive left ventricular hypertrophy. J Am Coll Cardiol. 1995;26: 195-202.
27. 27. Edvardsen. T, Rosen BD, Pan L, Jerosch-Herold M, Lai S, Hundley WG, Sinha S, Kronmal RA, Bluemke DA, Lima JA. Regional diastolic dysfunction in individuals with left ventricular hypertrophy measured, by tagged magnetic resonance imaging: the Multi-Ethnic Study of Atherosclerosis (MESA). Am Heart J. 2006;151:109-114. (Pubitemid 41815338)
28. Drazner MH, Rame JE, Marino EK, Gottdiener JS, Kitzman DW, Gardin JM, Manolio TA, Dries DL, Siscovick DS. Increased left ventricular mass is a risk factor for the development of a depressed left ventricular ejection fraction within five years: the Cardiovascular Health Study. J Am Coll Cardiol. 2004;43:2207-2215.
29. 29. Castillo E, Osman NF, Rosen BD, El Shehaby I, Pan L, Jerosch-Herold M, Lai S, Bluemke DA, Lima JA. Quantitative assessment of regional myocardial function with MR-tagging in a multi-center study: interobserver and intraobserver agreement of fast strain analysis with harmonic phase (HARP) MRI. J Cardiovasc Magn Reson. 2005;7:783-791. (Pubitemid 41770056)
30. 30. Carlsson M, Ugander M, Mosen H, Buhre T, Arheden H. Atrioventricular plane displacement is the major contributor to left ventricular pumping in healthy adults, athletes, and patients with dilated cardiomyopathy. Am J Physiol. 2007;292:H1452-H1459. (Pubitemid 46377133)