Urinary N-acetyl-beta-D-glucosaminidase (U-NAG) activity in children with vesicoureteral reflux

Bratislava Medical Journal

Volumn 110, Issue 2, 2009, Pages 69-72

  Skalova, S ^a   Rejtar, P ^a   Kutilek, S ^b,c  

^a CHARLES UNIVERSITY   (Czech Republic)

^b Center for Clinical and Basic Research CCBR   (Czech Republic)

^c Hospital Pardubice   (Czech Republic)

Author keywords

N acetyl D glucosaminidase; Vesicoureteral reflux

Indexed keywords

ACETYLGLUCOSAMINIDASE; CREATININE;

ARTICLE; CHILD; FEMALE; HUMAN; INFANT; KIDNEY TUBULE; MALE; PATHOPHYSIOLOGY; PRESCHOOL CHILD; URINE; VESICOURETERAL REFLUX;

ACETYLGLUCOSAMINIDASE; CHILD; CHILD, PRESCHOOL; CREATININE; FEMALE; HUMANS; INFANT; KIDNEY TUBULES; MALE; VESICO-URETERAL REFLUX;

EID: 70349755381     PISSN: 00069248     EISSN: 13360345     Source Type: Journal    
DOI: None     Document Type: Article

References (25)

1. Lebowitz RL, Olbing H, Parkkulainen KV, Smellie JM, Tamminen-Mobius TE. International system of radiographic grading of vesi-coureteric reflux. Internat Reflux Study Child 1985; 15: 105-109.
2. Schwab CW, Wu HY, Selman H, Smith GH, Snyder HM, Canning DA. Spontaneous resolution of vesicoureteral reflux: A 15-year perspective. J Urol 2002; 168: 2594-2599.
3. Stefanidis CJ, Siomou E. Imaging strategies for reflux diagnosis. Pediatr Nephrol 2007; 22: 937-947.
4. Bailey RR. The relationship of vesico-ureteric reflux to urinary tract infection and chronic pyelonefritis-reflux nephropathy. Clin Nephrol 1973; 1: 132-141.
5. Cendron M. Reflux nephropathy. J Pediatr Urol 2008, in press.
6. Mcllroy PJ, Abbott GD, Anderson, NG, Turner JG, Mogridge N, Wells JE. Outcome of primary vesicoureteric reflux detected following fetal renal pelvic dilatation. J Paediatr Child Health 2000; 36: 569-573.
7. Csáthy L, Pócsi I. Urinary N-acetyl-D-glucosaminidase determination in newborns and children: methods and diagnostic applications. Eur J Clin Chem Clin Bioch 1995; 33: 575-587.
8. Skálová S, Chládek J. Urinary N-acetyl-beta-D-glucosaminidase activity in healthy children. Nephrology 2004; 9: 19-21.
9. Dzurikova V, Krechnakova A. Nephrotoxicity of gentamicin and mercury in experiments on rats. Bratisl Lek Listy 1981; 76: 21-28.
10. Kovacikova L, Kunovsky P, Lakomy M, Illikova V, Skrak P, Tittel P, Cervenova O, Dedikova D. Peritoneal dialysis in children after cardiac surgery. Bratisl Lek Listy 2000; 101: 438-441.
11. Turecky L, Uhlikova E. Diagnostic significance of urinary enzymes in nephrology. Bratisl Lek Listy 2003; 104: 27-31.
12. Miyakita H, Puri P. Urinary levels of N-acetyl-beta-D-glucosaminidase: a simple marker for predicting tubular damage in higher grades of vesicoureteric reflux. Eur Urol 1994; 25: 135-137.
13. Fanos V, Mussap M, Osio D, Pizzini C, Plebani M. Urinary excretion of N-acetyl-beta-D-glucosaminidase and epidermal growth factor in paediatric patients receiving cefixime prophylaxis for recurrent urinary tract infections. Clin Drug Invest 2001; 21: 511-518.
14. Goonasekera CD, Shah V, Dillon MJ. Tubular proteinuria in reflux nephropathy: post ureteric reimplantation. Pediatr Nephrol 1996; 10: 559-563.
15. Tomlinson PA, Smellie JM, Prescod N, Dalton RN, Chantler C. Differentiation excretion of urinary reflux and reflux nephropathy. Pediatr Nephrol 1994; 8: 21-25.
16. Williams MA, Jones D, Noe HN. Urinary N-acetyl-beta-D-glucosaminidase as a screening technique for vesicoureteral reflux. Urology 1994; 43: 528-530.
17. Mattoo TK. A changing scenario in our understanding of vesicoureteral reflux in children. Indian Pediatrics 2006; 43: 111-115.
18. Silva JM, Santos Diniz JS, Marino VS, Lima EM, Cardoso LS, Vasconcelos MA et al. Clinical course of 735 children and adolescents with primary vesicoureteral reflux. Pediatr Nephrol 2006; 21: 981-988
19. Silva JM, Diniz JS, Silva AC, Azevedo MV, Pimenta MR, Oli-viera EA. Predictive factors of chronic kidney disease in severe vesicoureteral reflux. Pediatr Nephrol 2006; 21: 1285-1292.
20. Ozen HA, Whitaker RH. Does the severity of presentation in chil dren with vesicoureteric reflux relate to the severity of the disease or the need for operation? Brit J Urol 1987; 60: 110-112.
21. Lee JH, Son CH, Lee MS, Park Y. Vesicoureteral reflux increases the risk of renal scars: a study of unilateral reflux. Pediatr Nephrol 2006; 21: 1281-1284.
22. Arant BS Jr. Medical management of mild and moderate vesicoureteral reflux: follow up studies of infants and young children. A preliminary report of the Southwest Pediatric Nephrology Study Group. J Urol 1992; 148: 1683-1687
23. Gordon I, Barkovics M, Pindoria S, Cole TJ, Woolf AS. Primary vesicoureteric reflux as a predictor of renal damage in children hospitalized with urinary tract infection: A systematic review and meta-analy-sis. J Amer Soc Nephrol 2003; 14: 739-744.
24. Wheeler D, Vimalachandra D, Hodson EM, Roy LP, Smith G,Craig JC Antibiotics and surgery for vesicoureteric reflux: A metaanalysis of randomised controlled trials. Arch Dis Child 2003; 88:688-694.
25. Bensman A, Ulinski T. International Vesicoureteral Reflux Study:unsolved questions remaining. Pediatr Nephrol 2006; 21: 757-758.