Electrical impedence tomography and heterogeneity of pulmonary perfusion and ventilation in porcine acute lung injury

Acta Anaesthesiologica Scandinavica

Volumn 53, Issue 10, 2009, Pages 1300-1309

  Fagerberg, A ^a   SOndergaard S ^a   Karason, S ^b   Aneman A ^a  

^a SAHLGRENSKA UNIVERSITY HOSPITAL   (Sweden)

^b LANDSPITALI UNIVERSITY HOSPITAL   (Iceland)

Author keywords

[No Author keywords available]

Indexed keywords

ENDOTOXIN; DIAGNOSTIC AGENT;

ACUTE LUNG INJURY; ANESTHESIA; ANIMAL EXPERIMENT; ARTICLE; ARTIFICIAL VENTILATION; COMPUTER ASSISTED IMPEDANCE TOMOGRAPHY; FUNCTIONAL RESIDUAL CAPACITY; LUNG ALVEOLUS OXYGEN TENSION; LUNG COMPLIANCE; LUNG HEMODYNAMICS; LUNG PERFUSION; LUNG VENTILATION; NONHUMAN; PRIORITY JOURNAL; ANIMAL; DISEASE MODEL; ENDOTOXEMIA; HEMODYNAMICS; IMPEDANCE; LUNG FUNCTION TEST; LUNG VENTILATION PERFUSION RATIO; METHODOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; RISK; SWINE; TOMOGRAPHY; TREATMENT OUTCOME;

ACUTE LUNG INJURY; ANIMALS; DISEASE MODELS, ANIMAL; ELECTRIC IMPEDANCE; ENDOTOXEMIA; HEMODYNAMICS; LUNG COMPLIANCE; ODDS RATIO; PULMONARY VENTILATION; RESPIRATORY FUNCTION TESTS; SWINE; TOMOGRAPHY; TREATMENT OUTCOME; VENTILATION-PERFUSION RATIO;

EID: 70349747091     PISSN: 00015172     EISSN: 13996576     Source Type: Journal    
DOI: 10.1111/j.1399-6576.2009.02103.x     Document Type: Article

References (42)

1. Lambermont B, Kolh P, Detry O, Gerard P, Marcelle R, D'Orio V. Analysis of endotoxin effects on the intact pulmonary circulation. Cardiovasc Res 1999 41 : 275 281.
2. Weir EK, Mlczoch J, Reeves JT, Grover RF. Endotoxin and prevention of hypoxic pulmonary vasoconstriction. J Lab Clin Med 1976 88 : 975 983.
3. Gerbino AJ, Altemeier WA, Schimmel C, Glenny RW. Endotoxemia increases relative perfusion to dorsal-caudal lung regions. J Appl Physiol 2001 90 : 1508 1515.
4. Dahm PL, Jonson B, De Robertis E, Myhre E, Svantesson C, Thorne J, Blomquist S. The effects of nitric oxide inhalation on respiratory mechanics and gas exchange during endotoxaemia in the pig. Acta Anaesthesiol Scand 1998 42 : 536 544.
5. Gerbino AJ, McKinney S, Glenny RW. Correlation between ventilation and perfusion determines VA/Q heterogeneity in endotoxemia. J Appl Physiol 2000 88 : 1933 1942.
6. Huttemeier PC, Ringsted C, Eliasen K, Mogensen T. Ventilation-perfusion inequality during endotoxin-induced pulmonary vasoconstriction in conscious sheep: mechanisms of hypoxia. Clin Physiol 1988 8 : 351 358.
7. Forsgren P, Jakobson S, Modig J. True shunt in relation to venous admixture in an experimental porcine model of early ARDS. Acta Anaesthesiol Scand 1989 33 : 621 628.
8. Parsons PE, Worthen GS, Moore EE, Tate RM, Henson PM. The association of circulating endotoxin with the development of the adult respiratory distress syndrome. Am Rev Respir Dis 1989 140 : 294 301.
9. Dantzker DR, Brook CJ, Dehart P, Lynch JP, Weg JG. Ventilation-perfusion distributions in the adult respiratory distress syndrome. Am Rev Respir Dis 1979 120 : 1039 1052.
10. Ralph DD, Robertson HT, Weaver LJ, Hlastala MP, Carrico CJ, Hudson LD. Distribution of ventilation and perfusion during positive end-expiratory pressure in the adult respiratory distress syndrome. Am Rev Respir Dis 1985 131 : 54 60.
11. Matute-Bello G, Frevert CW, Martin TR. Animal models of acute lung injury. Am J Physiol Lung Cell Mol Physiol 2008 295 : L379 99.
12. Neumann P, Hedenstierna G. Ventilation-perfusion distributions in different porcine lung injury models. Acta Anaesthesiol Scand 2001 45 : 78 86.
13. Wagner PD. The multiple inert gas elimination technique (MIGET). Intensive Care Med 2008 34 : 994 1001.
14. Robertson HT, Hlastala MP. Microsphere maps of regional blood flow and regional ventilation. J Appl Physiol 2007 102 : 1265 1272.
15. Musch G, Venegas JG. Positron emission tomography imaging of regional pulmonary perfusion and ventilation. Proc Am Thorac Soc 2005 2 : 522 527, 508-9.
16. Vidal Melo MF, Layfield D, Harris RS, O'Neill K, Musch G, Richter T, Winkler T, Fischman AJ, Venegas JG. Quantification of regional ventilation-perfusion ratios with PET. J Nucl Med 2003 44 : 1982 1991.
17. Frerichs I. Electrical impedance tomography (EIT) in applications related to lung and ventilation: a review of experimental and clinical activities. Physiol Meas 2000 21 : R1 21.
18. Fagerberg A, Stenqvist O, Aneman A. Monitoring pulmonary perfusion by electrical impedance tomography: an evaluation in a pig model. Acta Anaesthesiol Scand 2009 53 : 152 158.
19. Meier T, Luepschen H, Karsten J, Leibecke T, Grossherr M, Gehring H, Leonhardt S. Assessment of regional lung recruitment and derecruitment during a PEEP trial based on electrical impedance tomography. Intensive Care Med 2008 34 : 543 550.
20. Kunst PW, Vonk Noordegraaf A, Hoekstra OS, Postmus PE, de Vries PM. Ventilation and perfusion imaging by electrical impedance tomography: a comparison with radionuclide scanning. Physiol Meas 1998 19 : 481 490.
21. Deibele JM, Luepschen H, Leonhardt S. Dynamic separation of pulmonary and cardiac changes in electrical impedance tomography. Physiol Meas 2008 29 : S1 14.
22. Smit HJ, Vonk Noordegraaf A, Marcus JT, Boonstra A, de Vries PM, Postmus PE. Determinants of pulmonary perfusion measured by electrical impedance tomography. Eur J Appl Physiol 2004 92 : 45 9.
23. Fagerberg A, Stenqvist O, Åneman A. Electrical impedance tomography applied to assess matching of pulmonary ventilation and perfusion in a porcine experimental model. Crit Care 2009 13 : R34.
24. Karason S, Sondergaard S, Lundin S, Wiklund J, Stenqvist O. Evaluation of pressure/volume loops based on intratracheal pressure measurements during dynamic conditions. Acta Anaesthesiol Scand 2000 44 : 571 577.
25. Sondergaard S, Karason S, Wiklund J, Lundin S, Stenqvist O. Alveolar pressure monitoring: an evaluation in a lung model and in patients with acute lung injury. Intensive Care Med 2003 29 : 955 962.
26. Baydur A, Behrakis PK, Zin WA, Jaeger M, Milic-Emili J. A simple method for assessing the validity of the esophageal balloon technique. Am Rev Respir Dis 1982 126 : 788 791.
27. Karason S, Karlsen KL, Lundin S, Stenqvist O. A simplified method for separate measurements of lung and chest wall mechanics in ventilator-treated patients. Acta Anaesthesiol Scand 1999 43 : 308 315.
28. Olegard C, Sondergaard S, Houltz E, Lundin S, Stenqvist O. Estimation of functional residual capacity at the bedside using standard monitoring equipment: a modified nitrogen washout/washin technique requiring a small change of the inspired oxygen fraction. Anesth Analg 2005 101 : 206 212, table of contents.
29. 2) gradient: a modeling analysis. Anesth Analg 2003 97 : 1846 1851.
30. Mols G, Brandes I, Kessler V, Lichtwarck-Aschoff M, Loop T, Geiger K, Guttmann J. Volume-dependent compliance in ARDS: proposal of a new diagnostic concept. Intensive Care Med 1999 25 : 1084 1091.
31. Mols G, Kessler V, Benzing A, Lichtwarck-Aschoff M, Geiger K, Guttmann J. Is pulmonary resistance constant, within the range of tidal volume ventilation, in patients with ARDS? Br J Anaesth 2001 86 : 176 182.
32. Bland JM, Altman DG. Calculating correlation coefficients with repeated observations: part 1 - correlation within subjects. BMJ 1995 310 : 446.
33. Wiener CM, Kirk W, Albert RK. Prone position reverses gravitational distribution of perfusion in dog lungs with oleic acid-induced injury. J Appl Physiol 1990 68 : 1386 1392.
34. D'Orio V, Halleux J, Rodriguez LM, Wahlen C, Marcelle R. Effects of escherichia coli endotoxin on pulmonary vascular resistance in intact dogs. Crit Care Med 1986 14 : 802 806.
35. Pearl RG, Baer ER, Siegel LC, Benson GV, Rice SA. Longitudinal distribution of pulmonary vascular resistance after endotoxin administration in sheep. Crit Care Med 1992 20 : 119 125.
36. Domino KB, Eisenstein BL, Tran T, Hlastala MP. Increased pulmonary perfusion worsens ventilation-perfusion matching. Anesthesiology 1993 79 : 817 826.
37. Galvin I, Drummond GB, Nirmalan M. Distribution of blood flow and ventilation in the lung: gravity is not the only factor. Br J Anaesth 2007 98 : 420 428. (Pubitemid 47072640)
38. Altemeier WA, McKinney S, Krueger M, Glenny RW. Effect of posture on regional gas exchange in pigs. J Appl Physiol 2004 97 : 2104 2111.
39. Hauge A, Bo G, Waaler BA. Interrelations between pulmonary liquid volumes and lung compliance. J Appl Physiol 1975 38 : 608 614.
40. Mutoh T, Lamm WJ, Embree LJ, Hildebrandt J, Albert RK. Volume infusion produces abdominal distension, lung compression, and chest wall stiffening in pigs. J Appl Physiol 1992 72 : 575 582.
41. Heinze H, Sedemund-Adib B, Heringlake M, Meier T, Eichler W. Changes in functional residual capacity during weaning from mechanical ventilation: a pilot study. Anesth Analg 2009 108 : 911 915.
42. Wilson TA, Beck KC. Contributions of ventilation and perfusion inhomogeneities to the VA/Q distribution. J Appl Physiol 1992 72 : 2298 2304.