메뉴 건너뛰기




Volumn 28, Issue 10, 2009, Pages 1199-1208

The unusual antibacterial activity of medical-grade Leptospermum honey: Antibacterial spectrum, resistance and transcriptome analysis

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFECTIVE AGENT; CIPROFLOXACIN; LEPTOSPERMUM EXTRACT; MEDIHONEY; NATURAL PRODUCT; OXACILLIN; TETRACYCLINE; UNCLASSIFIED DRUG;

EID: 70349696567     PISSN: 09349723     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10096-009-0763-z     Document Type: Article
Times cited : (193)

References (70)
  • 1
    • 33845903833 scopus 로고    scopus 로고
    • Drugs for bad bugs: Confronting the challenges of antibacterial discovery
    • DOI 10.1038/nrd2201, PII NRD2201
    • DJ Payne MN Gwynn DJ Holmes DL Pompliano 2007 Drugs for bad bugs: confronting the challenges of antibacterial discovery Nat Rev Drug Discov 6 29 40 10.1038/nrd2201 17159923 10.1038/nrd2201 1:CAS:528:DC%2BD28XhtlGktbfM (Pubitemid 46020284)
    • (2007) Nature Reviews Drug Discovery , vol.6 , Issue.1 , pp. 29-40
    • Payne, D.J.1    Gwynn, M.N.2    Holmes, D.J.3    Pompliano, D.L.4
  • 2
    • 10944272743 scopus 로고    scopus 로고
    • Antibacterial resistance worldwide: Causes, challenges and responses
    • DOI 10.1038/nm1145
    • SB Levy B Marshall 2004 Antibacterial resistance worldwide: causes, challenges and responses Nat Med 10 S122 S129 10.1038/nm1145 15577930 10.1038/nm1145 1:CAS:528:DC%2BD2cXhtVeht7fF (Pubitemid 40018235)
    • (2004) Nature Medicine , vol.10
    • Levy, S.B.1    Marshall, B.2
  • 3
    • 33747595241 scopus 로고    scopus 로고
    • The epidemiological profile of infections with multidrug-resistant Pseudomonas aeruginosa and Acinetobacter species
    • DOI 10.1086/504476
    • DL Paterson 2006 The epidemiological profile of infections with multidrug-resistant Pseudomonas aeruginosa and Acinetobacter species Clin Infect Dis 43 S43 S48 10.1086/504476 16894514 10.1086/504476 (Pubitemid 44267139)
    • (2006) Clinical Infectious Diseases , vol.43 , Issue.SUPPL. 2
    • Paterson, D.L.1
  • 4
    • 39449103059 scopus 로고    scopus 로고
    • The epidemic of antibiotic-resistant infections: A call to action for the medical community from the infectious diseases society of America
    • DOI 10.1086/524891
    • B Spellberg R Guidos D Gilbert J Bradley HW Boucher WM Scheld JG Bartlett J Edwards Jr Infectious Diseases Society of America 2008 The epidemic of antibiotic-resistant infections: a call to action for the medical community from the Infectious Diseases Society of America Clin Infect Dis 46 155 164 10.1086/524891 18171244 10.1086/524891 (Pubitemid 351269151)
    • (2008) Clinical Infectious Diseases , vol.46 , Issue.2 , pp. 155-164
    • Spellberg, B.1    Guidos, R.2    Gilbert, D.3    Bradley, J.4    Boucher, H.W.5    Scheld, W.M.6    Bartlett, J.G.7    Edwards Jr., J.8
  • 5
    • 33845872274 scopus 로고    scopus 로고
    • The potential clinical impact of low-level antibiotic resistance in Staphylococcus aureus
    • DOI 10.1093/jac/dkl429
    • F Goldstein 2007 The potential clinical impact of low-level antibiotic resistance in Staphylococcus aureus J Antimicrob Chemother 59 1 4 10.1093/jac/dkl429 17068009 10.1093/jac/dkl429 1:CAS:528:DC%2BD28XhtlChtL%2FF (Pubitemid 46017894)
    • (2007) Journal of Antimicrobial Chemotherapy , vol.59 , Issue.1 , pp. 1-4
    • Goldstein, F.1
  • 6
    • 31944435626 scopus 로고    scopus 로고
    • Novel mechanism of antibiotic resistance originating in vancomycin-intermediate Staphylococcus aureus
    • DOI 10.1128/AAC.50.2.428-438.2006
    • LZ Cui A Iwamoto JQ Lian HM Neoh T Maruyama Y Horikawa K Hiramatsu 2006 Novel mechanism of antibiotic resistance originating in vancomycin-intermediate Staphylococcus aureus Antimicrob Agents Chemother 50 428 438 10.1128/AAC.50.2.428-438.2006 16436693 10.1128/AAC.50.2.428-438.2006 1:CAS:528:DC%2BD28XhsFegtrg%3D (Pubitemid 43190949)
    • (2006) Antimicrobial Agents and Chemotherapy , vol.50 , Issue.2 , pp. 428-438
    • Cui, L.1    Iwamoto, A.2    Lian, J.-Q.3    Neoh, H.-M.4    Maruyama, T.5    Horikawa, Y.6    Hiramatsu, K.7
  • 8
    • 4143120992 scopus 로고    scopus 로고
    • Multidrug-resistant Acinetobacter infections: An emerging challenge to clinicians
    • DOI 10.1345/aph.1D592
    • R Jain LH Danziger 2004 Multidrug-resistant Acinetobacter infections: an emerging challenge to clinicians Ann Pharmacother 38 1449 1459 10.1345/aph.1D592 15280512 10.1345/aph.1D592 (Pubitemid 39100202)
    • (2004) Annals of Pharmacotherapy , vol.38 , Issue.9 , pp. 1449-1459
    • Jain, R.1    Danziger, L.H.2
  • 10
    • 33751564334 scopus 로고    scopus 로고
    • Treatment of sepsis: Current status of clinical immunotherapy
    • 17152200
    • A O'Callaghan HP Redmond 2006 Treatment of sepsis: current status of clinical immunotherapy Surgeon 4 355 361 17152200
    • (2006) Surgeon , vol.4 , pp. 355-361
    • O'Callaghan, A.1    Redmond, H.P.2
  • 11
    • 19544369670 scopus 로고    scopus 로고
    • Linezolid versus vancomycin in treatment of complicated skin and soft tissue infections
    • DOI 10.1128/AAC.49.6.2260-2266.2005
    • J Weigelt K Itani D Stevens W Lau M Dryden C Knirsch Linezolid CSSTI Study Group 2005 Linezolid versus vancomycin in treatment of complicated skin and soft tissue infections Antimicrob Agents Chemother 49 2260 2266 10.1128/AAC.49.6.2260-2266.2005 15917519 10.1128/AAC.49.6.2260-2266.2005 1:CAS:528:DC%2BD2MXkvFChu7k%3D (Pubitemid 40734452)
    • (2005) Antimicrobial Agents and Chemotherapy , vol.49 , Issue.6 , pp. 2260-2266
    • Weigelt, J.1    Itani, K.2    Stevens, D.3    Lau, W.4    Dryden, M.5    Knirsch, C.6
  • 12
    • 33747179934 scopus 로고    scopus 로고
    • The β-lactamase threat in Enterobacteriaceae, Pseudomonas and Acinetobacter
    • DOI 10.1016/j.tim.2006.07.008, PII S0966842X06001818
    • DM Livermore N Woodford 2006 The beta-lactamase threat in Enterobacteriaceae, Pseudomonas and Acinetobacter Trends Microbiol 14 413 420 10.1016/j.tim.2006.07.008 16876996 10.1016/j.tim.2006.07.008 1:CAS:528:DC%2BD28XotlWnsL8%3D (Pubitemid 44233298)
    • (2006) Trends in Microbiology , vol.14 , Issue.9 , pp. 413-420
    • Livermore, D.M.1    Woodford, N.2
  • 13
    • 32944458742 scopus 로고    scopus 로고
    • The evidence supporting the use of honey as a wound dressing
    • DOI 10.1177/1534734605286014
    • PC Molan 2006 The evidence supporting the use of honey as a wound dressing Int J Low Extrem Wounds 5 40 54 10.1177/1534734605286014 16543212 10.1177/1534734605286014 1:STN:280:DC%2BD287ltlOrsA%3D%3D (Pubitemid 43260786)
    • (2006) International Journal of Lower Extremity Wounds , vol.5 , Issue.1 , pp. 40-54
    • Molan, P.C.1
  • 14
    • 44349104856 scopus 로고    scopus 로고
    • The impact of Manuka honey dressings on the surface pH of chronic wounds
    • DOI 10.1111/j.1742-481X.2007.00424.x
    • GT Gethin S Cowman RM Conroy 2008 The impact of Manuka honey dressings on the surface pH of chronic wounds Int Wound J 5 185 194 10.1111/j.1742-481X. 2007.00424.x 18494624 10.1111/j.1742-481X.2007.00424.x (Pubitemid 351731665)
    • (2008) International Wound Journal , vol.5 , Issue.2 , pp. 185-194
    • Gethin, G.T.1    Cowman, S.2    Conroy, R.M.3
  • 15
    • 70349688609 scopus 로고    scopus 로고
    • Use of honey as a medicinal product in wound dressing (human and animal studies): A review
    • A Lotfi 2008 Use of honey as a medicinal product in wound dressing (human and animal studies): a review Res J Bio Sci 3 136 140
    • (2008) Res J Bio Sci , vol.3 , pp. 136-140
    • Lotfi, A.1
  • 16
    • 38349125968 scopus 로고    scopus 로고
    • Randomized clinical trial of honey-impregnated dressings for venous leg ulcers
    • Honey as Adjuvant Leg Ulcer Therapy trial collaborators. 10.1002/bjs.6059 18161896 10.1002/bjs.6059
    • A Jull N Walker V Parag P Molan A Rodgers Honey as Adjuvant Leg Ulcer Therapy trial collaborators 2008 Randomized clinical trial of honey-impregnated dressings for venous leg ulcers Br J Surg 95 175 182 10.1002/bjs.6059 18161896 10.1002/bjs.6059
    • (2008) Br J Surg , vol.95 , pp. 175-182
    • Jull, A.1    Walker, N.2    Parag, V.3    Molan, P.4    Rodgers, A.5
  • 17
    • 37249065105 scopus 로고    scopus 로고
    • Manuka honey dressing: An effective treatment for chronic wound infections
    • DOI 10.1016/j.bjoms.2006.09.013, PII S0266435606001860
    • BG Visavadia J Honeysett MH Danford 2008 Manuka honey dressing: an effective treatment for chronic wound infections Br J Oral Maxillofac Surg 46 55 56 10.1016/j.bjoms.2006.09.013 17113690 10.1016/j.bjoms.2006.09.013 (Pubitemid 350266129)
    • (2008) British Journal of Oral and Maxillofacial Surgery , vol.46 , Issue.1 , pp. 55-56
    • Visavadia, B.G.1    Honeysett, J.2    Danford, M.H.3
  • 18
    • 34547844197 scopus 로고    scopus 로고
    • A different and safe method of split thickness skin graft fixation: Medical honey application
    • DOI 10.1016/j.burns.2006.12.005, PII S0305417906007984
    • IM Emsen 2007 A different and safe method of split thickness skin graft fixation: medical honey application Burns 33 782 787 10.1016/j.burns.2006.12.005 17601670 10.1016/j.burns.2006.12.005 (Pubitemid 47248089)
    • (2007) Burns , vol.33 , Issue.6 , pp. 782-787
    • Emsen, I.M.1
  • 19
    • 38449106163 scopus 로고    scopus 로고
    • Effect of medical honey on wounds colonised or infected with MRSA
    • 17927079 1:STN:280:DC%2BD2sngsVyqtQ%3D%3D
    • G Blaser K Santos U Bode H Vetter A Simon 2007 Effect of medical honey on wounds colonised or infected with MRSA J Wound Care 16 325 328 17927079 1:STN:280:DC%2BD2sngsVyqtQ%3D%3D
    • (2007) J Wound Care , vol.16 , pp. 325-328
    • Blaser, G.1    Santos, K.2    Bode, U.3    Vetter, H.4    Simon, A.5
  • 20
    • 31044449583 scopus 로고    scopus 로고
    • Wound care with antibacterial honey (Medihoney) in pediatric hematology-oncology
    • DOI 10.1007/s00520-005-0874-8
    • A Simon K Sofka G Wiszniewsky G Blaser U Bode G Fleischhack 2006 Wound care with antibacterial honey (Medihoney) in pediatric hematology-oncology Support Care Cancer 14 91 97 10.1007/s00520-005-0874-8 16075253 10.1007/s00520-005-0874-8 (Pubitemid 43119603)
    • (2006) Supportive Care in Cancer , vol.14 , Issue.1 , pp. 91-97
    • Simon, A.1    Sofka, K.2    Wiszniewsky, G.3    Blaser, G.4    Bode, U.5    Fleischhack, G.6
  • 21
    • 80053463652 scopus 로고
    • The antibacterial activity of honey. 1. the nature of the antibacterial activity
    • PC Molan 1992 The antibacterial activity of honey. 1. The nature of the antibacterial activity Bee World 73 5 28
    • (1992) Bee World , vol.73 , pp. 5-28
    • Molan, P.C.1
  • 22
    • 50549180794 scopus 로고
    • The identification of inhibine, the antibacterial factor in honey, as hydrogen peroxide and its origin in a honey glucose-oxidase system
    • 10.1016/0006-3002(63)90359-7 14000328 10.1016/0006-3002(63)90359-7 1:CAS:528:DyaF3sXosFWrug%3D%3D
    • JW White Jr MH Subers AI Schepartz 1963 The identification of inhibine, the antibacterial factor in honey, as hydrogen peroxide and its origin in a honey glucose-oxidase system Biochim Biophys Acta 73 57 70 10.1016/0006-3002(63) 90359-7 14000328 10.1016/0006-3002(63)90359-7 1:CAS:528:DyaF3sXosFWrug%3D%3D
    • (1963) Biochim Biophys Acta , vol.73 , pp. 57-70
    • White Jr, J.W.1    Subers, M.H.2    Schepartz, A.I.3
  • 23
    • 0025937695 scopus 로고
    • A survey of the antibacterial activity of some New Zealand honeys
    • 1687577 1:STN:280:DyaK383mtVeltA%3D%3D
    • KL Allen PC Molan GM Reid 1991 A survey of the antibacterial activity of some New Zealand honeys J Pharm Pharmacol 43 817 822 1687577 1:STN:280:DyaK383mtVeltA%3D%3D
    • (1991) J Pharm Pharmacol , vol.43 , pp. 817-822
    • Allen, K.L.1    Molan, P.C.2    Reid, G.M.3
  • 24
    • 39649093370 scopus 로고    scopus 로고
    • Isolation by HPLC and characterisation of the bioactive fraction of New Zealand manuka (Leptospermum scoparium) honey
    • 10.1016/j.carres.2007.12.011 18194804 10.1016/j.carres.2007.12.011 1:CAS:528:DC%2BD1cXis1CgtLo%3D
    • CJ Adams CH Boult BJ Deadman JM Farr MNC Grainger M Manley-Harris MJ Snow 2008 Isolation by HPLC and characterisation of the bioactive fraction of New Zealand manuka (Leptospermum scoparium) honey Carbohydr Res 343 651 659 10.1016/j.carres.2007.12.011 18194804 10.1016/j.carres.2007.12.011 1:CAS:528:DC%2BD1cXis1CgtLo%3D
    • (2008) Carbohydr Res , vol.343 , pp. 651-659
    • Adams, C.J.1    Boult, C.H.2    Deadman, B.J.3    Farr, J.M.4    Grainger, M.N.C.5    Manley-Harris, M.6    Snow, M.J.7
  • 25
    • 48649098085 scopus 로고    scopus 로고
    • Identification and quantification of methylglyoxal as the dominant antibacterial constituent of Manuka (Leptospermum scoparium) honeys from New Zealand
    • 10.1002/mnfr.200700282 18210383 10.1002/mnfr.200700282 1:CAS:528:DC%2BD1cXltlensr0%3D
    • E Mavric S Wittmann G Barth T Henle 2008 Identification and quantification of methylglyoxal as the dominant antibacterial constituent of Manuka (Leptospermum scoparium) honeys from New Zealand Mol Nutr Food Res 52 483 489 10.1002/mnfr.200700282 18210383 10.1002/mnfr.200700282 1:CAS:528: DC%2BD1cXltlensr0%3D
    • (2008) Mol Nutr Food Res , vol.52 , pp. 483-489
    • Mavric, E.1    Wittmann, S.2    Barth, G.3    Henle, T.4
  • 26
    • 38749130432 scopus 로고    scopus 로고
    • The tandem of free radicals and methylglyoxal
    • 10.1016/j.cbi.2007.11.009 18164697 10.1016/j.cbi.2007.11.009 1:CAS:528:DC%2BD1cXhsVSiurs%3D
    • MP Kalapos 2008 The tandem of free radicals and methylglyoxal Chem Biol Interact 171 251 271 10.1016/j.cbi.2007.11.009 18164697 10.1016/j.cbi.2007.11. 009 1:CAS:528:DC%2BD1cXhsVSiurs%3D
    • (2008) Chem Biol Interact , vol.171 , pp. 251-271
    • Kalapos, M.P.1
  • 27
    • 26244440553 scopus 로고    scopus 로고
    • Using microarray gene signatures to elucidate mechanisms of antibiotic action and resistance
    • DOI 10.1016/S1359-6446(05)03566-X, PII S135964460503566X
    • MD Brazas REW Hancock 2005 Using microarray gene signatures to elucidate mechanisms of antibiotic action and resistance Drug Discov Today 10 1245 1252 10.1016/S1359-6446(05)03566-X 16213417 10.1016/S1359-6446(05)03566-X 1:CAS:528:DC%2BD2MXhtVGgsLzL (Pubitemid 41411435)
    • (2005) Drug Discovery Today , vol.10 , Issue.18 , pp. 1245-1252
    • Brazas, M.D.1    Hancock, R.E.W.2
  • 28
    • 35348867973 scopus 로고    scopus 로고
    • The complexities of antibiotic action
    • DOI 10.1038/msb4100184, PII MSB4100184
    • RE Hancock 2007 The complexities of antibiotic action Mol Syst Biol 3 142 10.1038/msb4100184 17940532 10.1038/msb4100184 (Pubitemid 47587024)
    • (2007) Molecular Systems Biology , vol.3 , pp. 142
    • Hancock, R.E.W.1
  • 30
    • 4644245934 scopus 로고    scopus 로고
    • The impact of transcriptome and proteome analyses on antibiotic drug discovery
    • DOI 10.1016/j.mib.2004.08.010, PII S1369527404001043
    • C Freiberg H Brötz-Oesterhelt H Labischinski 2004 The impact of transcriptome and proteome analyses on antibiotic drug discovery Curr Opin Microbiol 7 451 459 10.1016/j.mib.2004.08.010 15451499 10.1016/j.mib.2004.08.010 1:CAS:528:DC%2BD2cXnvFant7k%3D (Pubitemid 39297124)
    • (2004) Current Opinion in Microbiology , vol.7 , Issue.5 , pp. 451-459
    • Freiberg, C.1    Brotz-Oesterhelt, H.2    Labischinski, H.3
  • 31
    • 33748698411 scopus 로고    scopus 로고
    • The world of subinhibitory antibiotic concentrations
    • DOI 10.1016/j.mib.2006.08.006, PII S1369527406001287, Antimicrobials/Genomics
    • J Davies GB Spiegelman G Yim 2006 The world of subinhibitory antibiotic concentrations Curr Opin Microbiol 9 445 453 10.1016/j.mib.2006.08.006 16942902 10.1016/j.mib.2006.08.006 1:CAS:528:DC%2BD28XpvFSis7s%3D (Pubitemid 44397635)
    • (2006) Current Opinion in Microbiology , vol.9 , Issue.5 , pp. 445-453
    • Davies, J.1    Spiegelman, G.B.2    Yim, G.3
  • 32
    • 36248994803 scopus 로고    scopus 로고
    • The targets of currently used antibacterial agents: Lessons for drug discovery
    • DOI 10.2174/138161207782110408
    • RP Lange HH Locher PC Wyss RL Then 2007 The targets of currently used antibacterial agents: lessons for drug discovery Curr Pharm Des 13 3140 3154 10.2174/138161207782110408 17979755 10.2174/138161207782110408 1:CAS:528:DC%2BD2sXhtlarurnE (Pubitemid 350130963)
    • (2007) Current Pharmaceutical Design , vol.13 , Issue.30 , pp. 3140-3154
    • Lange, R.P.1    Locher, H.H.2    Wyss, P.C.3    Then, R.L.4
  • 33
    • 34447254962 scopus 로고    scopus 로고
    • Using genomics to identify new targets and counteract resistance to antibiotics
    • DOI 10.1517/13543776.17.6.667
    • J Alvarez M Vicente 2007 Using genomics to identify new targets and counteract resistance to antibiotics Expert Opin Ther Pat 17 667 674 10.1517/13543776.17.6.667 1:CAS:528:DC%2BD2sXntFWqt7w%3D (Pubitemid 47045529)
    • (2007) Expert Opinion on Therapeutic Patents , vol.17 , Issue.6 , pp. 667-674
    • Alvarez, J.1    Vicente, M.2
  • 34
    • 0036430016 scopus 로고    scopus 로고
    • The sensitivity to honey of Gram-positive cocci of clinical significance isolated from wounds
    • DOI 10.1046/j.1365-2672.2002.01761.x
    • RA Cooper PC Molan KG Harding 2002 The sensitivity to honey of Gram-positive cocci of clinical significance isolated from wounds J Appl Microbiol 93 857 863 10.1046/j.1365-2672.2002.01761.x 12392533 10.1046/j.1365-2672.2002.01761.x 1:STN:280:DC%2BD38notFClsw%3D%3D (Pubitemid 35340889)
    • (2002) Journal of Applied Microbiology , vol.93 , Issue.5 , pp. 857-863
    • Cooper, R.A.1    Molan, P.C.2    Harding, K.G.3
  • 36
    • 1842453825 scopus 로고    scopus 로고
    • Structure of the histone-like protein H-NS and its role in regulation and genome superstructure
    • DOI 10.1016/j.mib.2004.02.001, PII S1369527404000141
    • S Rimsky 2004 Structure of the histone-like protein H-NS and its role in regulation and genome superstructure Curr Opin Microbiol 7 109 114 10.1016/j.mib.2004.02.001 15063845 10.1016/j.mib.2004.02.001 1:CAS:528:DC%2BD2cXivVKrsbY%3D (Pubitemid 38447041)
    • (2004) Current Opinion in Microbiology , vol.7 , Issue.2 , pp. 109-114
    • Rimsky, S.1
  • 37
    • 36549004138 scopus 로고    scopus 로고
    • Stress responses of bacteria
    • DOI 10.1016/j.sbi.2007.08.004, PII S0959440X0700111X, Catalysis and Regulation /Protein
    • J Marles-Wright RJ Lewis 2007 Stress responses of bacteria Curr Opin Struct Biol 17 755 760 10.1016/j.sbi.2007.08.004 17920859 10.1016/j.sbi.2007.08. 004 1:CAS:528:DC%2BD2sXhtlyktLbN (Pubitemid 350180403)
    • (2007) Current Opinion in Structural Biology , vol.17 , Issue.6 , pp. 755-760
    • Marles-Wright, J.1    Lewis, R.J.2
  • 38
    • 0036714331 scopus 로고    scopus 로고
    • s (RpoS) subunit of RNA polymerase
    • DOI 10.1128/MMBR.66.3.373-395.2002
    • R Hengge-Aronis 2002 Signal transduction and regulatory mechanisms involved in control of the σS RpoS subunit of RNA polymerase Microbiol Mol Biol Rev 66 373 395 10.1128/MMBR.66.3.373-395.2002 12208995 10.1128/MMBR.66.3.373-395.2002 1:CAS:528:DC%2BD38XnsFOitr4%3D (Pubitemid 35001135)
    • (2002) Microbiology and Molecular Biology Reviews , vol.66 , Issue.3 , pp. 373-395
    • Hengge-Aronis, R.1
  • 39
    • 39249084651 scopus 로고    scopus 로고
    • RpoS regulation of gene expression during exponential growth of Escherichia coli K12
    • 10.1007/s00438-007-0311-4 18158608 10.1007/s00438-007-0311-4 1:CAS:528:DC%2BD1cXhvFyrsb4%3D
    • T Dong MG Kirchhof HE Schellhorn 2008 RpoS regulation of gene expression during exponential growth of Escherichia coli K12 Mol Genet Genomics 279 267 277 10.1007/s00438-007-0311-4 18158608 10.1007/s00438-007-0311-4 1:CAS:528:DC%2BD1cXhvFyrsb4%3D
    • (2008) Mol Genet Genomics , vol.279 , pp. 267-277
    • Dong, T.1    Kirchhof, M.G.2    Schellhorn, H.E.3
  • 40
    • 0142011056 scopus 로고    scopus 로고
    • Transcriptional regulation of drug efflux genes by EvgAS, a two-component system in Escherichia coli
    • 10.1099/mic.0.26460-0 14523115 10.1099/mic.0.26460-0 1:CAS:528: DC%2BD3sXosVGqtbY%3D
    • Y Eguchi T Oshima H Mori R Aono K Yamamoto A Ishihama R Utsumi 2003 Transcriptional regulation of drug efflux genes by EvgAS, a two-component system in Escherichia coli Microbiology 149 2819 2828 10.1099/mic.0.26460-0 14523115 10.1099/mic.0.26460-0 1:CAS:528:DC%2BD3sXosVGqtbY%3D
    • (2003) Microbiology , vol.149 , pp. 2819-2828
    • Eguchi, Y.1    Oshima, T.2    Mori, H.3    Aono, R.4    Yamamoto, K.5    Ishihama, A.6    Utsumi, R.7
  • 41
    • 2342501446 scopus 로고    scopus 로고
    • Signal Transduction Cascade between EvgA/EvgS and PhoP/PhoQ Two-Component Systems of Escherichia coli
    • DOI 10.1128/JB.186.10.3006-3014.2004
    • Y Eguchi T Okada S Minagawa T Oshima H Mori K Yamamoto A Ishihama R Utsumi 2004 Signal transduction cascade between EvgA/EvgS and PhoP/PhoQ two-component systems of Escherichia coli J Bacteriol 186 3006 3014 10.1128/JB.186.10.3006-3014.2004 15126461 10.1128/JB.186.10.3006-3014.2004 1:CAS:528:DC%2BD2cXktVGhur4%3D (Pubitemid 38609743)
    • (2004) Journal of Bacteriology , vol.186 , Issue.10 , pp. 3006-3014
    • Eguchi, Y.1    Okada, T.2    Minagawa, S.3    Oshima, T.4    Mori, H.5    Yamamoto, K.6    Ishihama, A.7    Utsumi, R.8
  • 42
    • 65249178418 scopus 로고    scopus 로고
    • Medical honey for wound care-still the 'latest resort'?
    • doi:10.1093/ecam/nem175
    • Simon A, Traynor K, Santos K, Blaser G, Bode U, Molan P (2009) Medical honey for wound care-still the 'latest resort'? eCAM 6:165-173. doi: 10.1093/ecam/nem175
    • (2009) ECAM , vol.6 , pp. 165-173
    • Simon, A.1    Traynor, K.2    Santos, K.3    Blaser, G.4    Bode, U.5    Molan, P.6
  • 43
    • 70349560089 scopus 로고    scopus 로고
    • The potential for honey in the management of wounds and infection
    • SE Blair DA Carter 2005 The potential for honey in the management of wounds and infection Aust Infect Contr 10 24 31
    • (2005) Aust Infect Contr , vol.10 , pp. 24-31
    • Blair, S.E.1    Carter, D.A.2
  • 44
    • 0033941621 scopus 로고    scopus 로고
    • Susceptibility of multiresistant strains of Burkholderia cepacia to honey
    • 10.1046/j.1472-765x.2000.00756.x 10886608 10.1046/j.1472-765x.2000.00756. x 1:STN:280:DC%2BD3cvhslejtA%3D%3D
    • RA Cooper P Wigley NF Burton 2000 Susceptibility of multiresistant strains of Burkholderia cepacia to honey Lett Appl Microbiol 31 20 24 10.1046/j.1472-765x.2000.00756.x 10886608 10.1046/j.1472-765x.2000.00756.x 1:STN:280:DC%2BD3cvhslejtA%3D%3D
    • (2000) Lett Appl Microbiol , vol.31 , pp. 20-24
    • Cooper, R.A.1    Wigley, P.2    Burton, N.F.3
  • 45
    • 0036861597 scopus 로고    scopus 로고
    • The efficacy of honey in inhibiting strains of Pseudomonas aeruginosa from infected burns
    • 10.1097/00004630-200211000-00002 12432313 10.1097/00004630-200211000- 00002 1:STN:280:DC%2BD38nntFansg%3D%3D
    • RA Cooper E Halas PC Molan 2002 The efficacy of honey in inhibiting strains of Pseudomonas aeruginosa from infected burns J Burn Care Rehabil 23 366 370 10.1097/00004630-200211000-00002 12432313 10.1097/00004630-200211000-00002 1:STN:280:DC%2BD38nntFansg%3D%3D
    • (2002) J Burn Care Rehabil , vol.23 , pp. 366-370
    • Cooper, R.A.1    Halas, E.2    Molan, P.C.3
  • 46
    • 24044498346 scopus 로고    scopus 로고
    • The antibacterial activity of honey against coagulase-negative staphylococci
    • DOI 10.1093/jac/dki193
    • VM French RA Cooper PC Molan 2005 The antibacterial activity of honey against coagulase-negative staphylococci J Antimicrob Chemother 56 228 231 10.1093/jac/dki193 15941774 10.1093/jac/dki193 1:CAS:528:DC%2BD2MXmsV2iuro%3D (Pubitemid 41418363)
    • (2005) Journal of Antimicrobial Chemotherapy , vol.56 , Issue.1 , pp. 228-231
    • French, V.M.1    Cooper, R.A.2    Molan, P.C.3
  • 47
    • 0345832055 scopus 로고    scopus 로고
    • Adaptive Resistance to Biocides in Salmonella enterica and Escherichia coli O157 and Cross-Resistance to Antimicrobial Agents
    • DOI 10.1128/JCM.42.1.73-78.2004
    • M Braoudaki AC Hilton 2004 Adaptive resistance to biocides in Salmonella enterica and Escherichia coli O157 and cross-resistance to antimicrobial agents J Clin Microbiol 42 73 78 10.1128/JCM.42.1.73-78.2004 14715734 10.1128/JCM.42.1.73-78.2004 1:CAS:528:DC%2BD2cXht1Wnsb0%3D (Pubitemid 38082701)
    • (2004) Journal of Clinical Microbiology , vol.42 , Issue.1 , pp. 73-78
    • Braoudaki, M.1    Hilton, A.C.2
  • 48
    • 0347419266 scopus 로고    scopus 로고
    • Bacterial production of methylglyoxal: A survival strategy or death by misadventure?
    • 10.1042/BST0311406 14641075 10.1042/BST0311406 1:CAS:528: DC%2BD3sXps12jt7Y%3D
    • IR Booth GP Ferguson S Miller C Li B Gunasekera S Kinghorn 2003 Bacterial production of methylglyoxal: a survival strategy or death by misadventure? Biochem Soc Trans 31 1406 1408 10.1042/BST0311406 14641075 10.1042/BST0311406 1:CAS:528:DC%2BD3sXps12jt7Y%3D
    • (2003) Biochem Soc Trans , vol.31 , pp. 1406-1408
    • Booth, I.R.1    Ferguson, G.P.2    Miller, S.3    Li, C.4    Gunasekera, B.5    Kinghorn, S.6
  • 49
    • 0004051807 scopus 로고
    • London: Heinemann (for the Bee Research Association)
    • Crane E (1976) Honey, a comprehensive survey. London: Heinemann (for the Bee Research Association), p 608
    • (1976) Honey, A Comprehensive Survey , pp. 608
    • Crane, E.1
  • 50
    • 0034243556 scopus 로고    scopus 로고
    • Means of bacterial resistance
    • 11028184 1:STN:280:DC%2BD3cvnslOgtw%3D%3D
    • P Moreillon 2000 Means of bacterial resistance Rev Med Suisse Romande 120 641 650 11028184 1:STN:280:DC%2BD3cvnslOgtw%3D%3D
    • (2000) Rev Med Suisse Romande , vol.120 , pp. 641-650
    • Moreillon, P.1
  • 51
    • 0036050858 scopus 로고    scopus 로고
    • Active efflux, a common mechanism for biocide and antibiotic resistance
    • 10.1046/j.1365-2672.92.5s1.4.x 12000614 10.1046/j.1365-2672.92.5s1.4.x
    • SB Levy 2002 Active efflux, a common mechanism for biocide and antibiotic resistance J Appl Microbiol 92 65S 71S 10.1046/j.1365-2672.92.5s1.4.x 12000614 10.1046/j.1365-2672.92.5s1.4.x
    • (2002) J Appl Microbiol , vol.92
    • Levy, S.B.1
  • 52
    • 1442349125 scopus 로고    scopus 로고
    • Killing by Ampicillin and Ofloxacin Induces Overlapping Changes in Escherichia coli Transcription Profile
    • DOI 10.1128/AAC.48.3.890-896.2004
    • N Kaldalu R Mei K Lewis 2004 Killing by ampicillin and ofloxacin induces overlapping changes in Escherichia coli transcription profile Antimicrob Agents Chemother 48 890 896 10.1128/AAC.48.3.890-896.2004 14982780 10.1128/AAC.48.3. 890-896.2004 1:CAS:528:DC%2BD2cXitVGht70%3D (Pubitemid 38280340)
    • (2004) Antimicrobial Agents and Chemotherapy , vol.48 , Issue.3 , pp. 890-896
    • Kaldalu, N.1    Mei, R.2    Lewis, K.3
  • 53
    • 14744279815 scopus 로고    scopus 로고
    • Global expression of prophage genes in Escherichia coli O157:H7 strain EDL933 in response to norfloxacin
    • DOI 10.1128/AAC.49.3.931-944.2005
    • S Herold J Siebert A Huber H Schmidt 2005 Global expression of prophage genes in Escherichia coli O157:H7 strain EDL933 in response to norfloxacin Antimicrob Agents Chemother 49 931 944 10.1128/AAC.49.3.931-944.2005 15728886 10.1128/AAC.49.3.931-944.2005 1:CAS:528:DC%2BD2MXit12mtLs%3D (Pubitemid 40327707)
    • (2005) Antimicrobial Agents and Chemotherapy , vol.49 , Issue.3 , pp. 931-944
    • Herold, S.1    Siebert, J.2    Huber, A.3    Schmidt, H.4
  • 55
    • 0037228233 scopus 로고    scopus 로고
    • Transcriptional profile of the Escherichia coli response to the antimicrobial insect peptide cecropin A
    • DOI 10.1128/AAC.47.1.1-6.2003
    • RW Hong M Shchepetov JN Weiser PH Axelsen 2003 Transcriptional profile of the Escherichia coli response to the antimicrobial insect peptide cecropin A Antimicrob Agents Chemother 47 1 6 10.1128/AAC.47.1.1-6.2003 12499161 10.1128/AAC.47.1.1-6.2003 1:CAS:528:DC%2BD3sXis12jug%3D%3D (Pubitemid 36070334)
    • (2003) Antimicrobial Agents and Chemotherapy , vol.47 , Issue.1 , pp. 1-6
    • Hong, R.W.1    Shchepetov, M.2    Weiser, J.N.3    Axelsen, P.H.4
  • 56
    • 4344573440 scopus 로고    scopus 로고
    • Genome-wide transcriptional profiling of the Escherichia coli response to a proline-rich antimicrobial peptide
    • DOI 10.1128/AAC.48.9.3260-3267.2004
    • L Tomasinsig M Scocchi R Mettulio M Zanetti 2004 Genome-wide transcriptional profiling of the Escherichia coli response to a proline-rich antimicrobial peptide Antimicrob Agents Chemother 48 3260 3267 10.1128/AAC.48.9.3260-3267.2004 15328082 10.1128/AAC.48.9.3260-3267.2004 1:CAS:528:DC%2BD2cXnsVeiurY%3D (Pubitemid 39129316)
    • (2004) Antimicrobial Agents and Chemotherapy , vol.48 , Issue.9 , pp. 3260-3267
    • Tomasinsig, L.1    Scocchi, M.2    Mettulio, R.3    Zanetti, M.4
  • 57
    • 0036224939 scopus 로고    scopus 로고
    • Over 1000 genes are involved in the DNA damage response of Escherichia coli
    • DOI 10.1046/j.1365-2958.2002.02878.x
    • PP Khil RD Camerini-Otero 2002 Over 1000 genes are involved in the DNA damage response of Escherichia coli Mol Microbiol 44 89 105 10.1046/j.1365-2958. 2002.02878.x 11967071 10.1046/j.1365-2958.2002.02878.x 1:CAS:528: DC%2BD38XjsFGrt7o%3D (Pubitemid 34429767)
    • (2002) Molecular Microbiology , vol.44 , Issue.1 , pp. 89-105
    • Khil, P.P.1    Camerini-Otero, R.D.2
  • 58
    • 0036069537 scopus 로고    scopus 로고
    • Gene expression profiling of Escherichia coli growth transitions: An expanded stringent response model
    • DOI 10.1046/j.1365-2958.2002.03001.x
    • DE Chang DJ Smalley T Conway 2002 Gene expression profiling of Escherichia coli growth transitions: an expanded stringent response model Mol Microbiol 45 289 306 10.1046/j.1365-2958.2002.03001.x 12123445 10.1046/j.1365-2958.2002.03001.x 1:CAS:528:DC%2BD38XmtVehs74%3D (Pubitemid 34779825)
    • (2002) Molecular Microbiology , vol.45 , Issue.2 , pp. 289-306
    • Chang, D.-E.1    Smalley, D.J.2    Conway, T.3
  • 59
    • 0029843811 scopus 로고    scopus 로고
    • Back to log phase: Sigma S as a global regulator in the osmotic control of gene expression in Escherichia coli
    • 10.1046/j.1365-2958.1996.511405.x 8885260 10.1046/j.1365-2958.1996. 511405.x 1:CAS:528:DyaK28Xls1ekurw%3D
    • R Hengge-Aronis 1996 Back to log phase: sigma S as a global regulator in the osmotic control of gene expression in Escherichia coli Mol Microbiol 21 887 893 10.1046/j.1365-2958.1996.511405.x 8885260 10.1046/j.1365-2958.1996.511405.x 1:CAS:528:DyaK28Xls1ekurw%3D
    • (1996) Mol Microbiol , vol.21 , pp. 887-893
    • Hengge-Aronis, R.1
  • 60
    • 0031885522 scopus 로고    scopus 로고
    • Importance of RpoS and Dps in survival of exposure of both exponential- and stationary-phase Escherichia coli cells to the electrophile N-ethylmaleimide
    • 9495739 1:CAS:528:DyaK1cXhsFyjurw%3D
    • GP Ferguson RI Creighton Y Nikolaev IR Booth 1998 Importance of RpoS and Dps in survival of exposure of both exponential- and stationary-phase Escherichia coli cells to the electrophile N-ethylmaleimide J Bacteriol 180 1030 1036 9495739 1:CAS:528:DyaK1cXhsFyjurw%3D
    • (1998) J Bacteriol , vol.180 , pp. 1030-1036
    • Ferguson, G.P.1    Creighton, R.I.2    Nikolaev, Y.3    Booth, I.R.4
  • 61
    • 28844435746 scopus 로고    scopus 로고
    • Acid response of exponentially growing Escherichia coli K-12
    • DOI 10.1016/j.micres.2005.06.002, PII S0944501305000650
    • V Seputiene A Daugelavicius K Suziedelis E Suziedeliene 2006 Acid response of exponentially growing Escherichia coli K-12 Microbiol Res 161 65 74 10.1016/j.micres.2005.06.002 16338593 10.1016/j.micres.2005.06.002 1:CAS:528:DC%2BD28XhslOit7w%3D (Pubitemid 41773116)
    • (2006) Microbiological Research , vol.161 , Issue.1 , pp. 65-74
    • Seputiene, V.1    Daugelavicius, A.2    Suziedelis, K.3    Suziedeliene, E.4
  • 62
    • 34047116370 scopus 로고    scopus 로고
    • Molecular mechanisms of pathogenicity: How do pathogenic microorganisms develop cross-kingdom host jumps?
    • DOI 10.1111/j.1574-6976.2007.00065.x
    • P van Baarlen A van Belkum RC Summerbell PW Crous BPHJ Thomma 2007 Molecular mechanisms of pathogenicity: how do pathogenic microorganisms develop cross-kingdom host jumps? FEMS Microbiol Rev 31 239 277 10.1111/j.1574-6976. 2007.00065.x 17326816 10.1111/j.1574-6976.2007.00065.x (Pubitemid 46525309)
    • (2007) FEMS Microbiology Reviews , vol.31 , Issue.3 , pp. 239-277
    • Van Baarlen, P.1    Van Belkum, A.2    Summerbell, R.C.3    Crous, P.W.4    Thomma, B.P.H.J.5
  • 63
    • 33646849448 scopus 로고    scopus 로고
    • Honey has an antifungal effect against Candida species
    • DOI 10.1080/13693780500417037, PII T0235810451138
    • J Irish DA Carter T Shokohi SE Blair 2006 Honey has an antifungal effect against Candida species Med Mycol 44 289 291 10.1080/13693780500417037 16702110 10.1080/13693780500417037 (Pubitemid 43771937)
    • (2006) Medical Mycology , vol.44 , Issue.3 , pp. 289-291
    • Irish, J.1    Carter, D.A.2    Shokohi, T.3    Blair, S.E.4
  • 64
    • 0030319551 scopus 로고    scopus 로고
    • The sensitivity of dermatophytes to the antimicrobial activity of manuka honey and other honey
    • 1:CAS:528:DyaK2sXmtVKgs7c%3D
    • NF Brady PC Molan CG Harfoot 1996 The sensitivity of dermatophytes to the antimicrobial activity of manuka honey and other honey Pharm Sci 2 471 473 1:CAS:528:DyaK2sXmtVKgs7c%3D
    • (1996) Pharm Sci , vol.2 , pp. 471-473
    • Brady, N.F.1    Molan, P.C.2    Harfoot, C.G.3
  • 65
    • 0031691147 scopus 로고    scopus 로고
    • Methylglyoxal production in bacteria: Suicide or survival?
    • DOI 10.1007/s002030050635
    • GP Ferguson S Tötemeyer MJ MacLean IR Booth 1998 Methylglyoxal production in bacteria: suicide or survival? Arch Microbiol 170 209 219 10.1007/s002030050635 9732434 10.1007/s002030050635 1:CAS:528:DyaK1cXms1Gjt74%3D (Pubitemid 28430377)
    • (1998) Archives of Microbiology , vol.170 , Issue.4 , pp. 209-219
    • Ferguson, G.P.1    Totemeyer, S.2    MacLean, M.J.3    Booth, I.R.4
  • 66
    • 0031983922 scopus 로고    scopus 로고
    • From famine to feast: The role of methylglyoxal production in Escherichia coli
    • DOI 10.1046/j.1365-2958.1998.00700.x
    • S Tötemeyer NA Booth WW Nichols B Dunbar IR Booth 1998 From famine to feast: the role of methylglyoxal production in Escherichia coli Mol Microbiol 27 553 562 10.1046/j.1365-2958.1998.00700.x 9489667 10.1046/j.1365-2958.1998. 00700.x (Pubitemid 28045737)
    • (1998) Molecular Microbiology , vol.27 , Issue.3 , pp. 553-562
    • Totemeyer, S.1    Booth, N.A.2    Nichols, W.W.3    Dunbar, B.4    Booth, I.R.5
  • 67
    • 0033938726 scopus 로고    scopus 로고
    • Identification of sequences encoding the detoxification metalloisomerase glyoxalase i in microbial genomes from several pathogenic organisms
    • 10824093 1:CAS:528:DC%2BD3cXksVGlurw%3D
    • SL Clugston JF Honek 2000 Identification of sequences encoding the detoxification metalloisomerase glyoxalase I in microbial genomes from several pathogenic organisms J Mol Evol 50 491 495 10824093 1:CAS:528: DC%2BD3cXksVGlurw%3D
    • (2000) J Mol Evol , vol.50 , pp. 491-495
    • Clugston, S.L.1    Honek, J.F.2
  • 68
    • 0037458207 scopus 로고    scopus 로고
    • A novel aldo-keto reductase from Escherichia coli can increase resistance to methylglyoxal toxicity
    • 10.1111/j.1574-6968.2003.tb11503.x 12583903 10.1111/j.1574-6968.2003. tb11503.x 1:CAS:528:DC%2BD3sXhtVGjsrg%3D
    • AW Grant G Steel H Waugh EM Ellis 2003 A novel aldo-keto reductase from Escherichia coli can increase resistance to methylglyoxal toxicity FEMS Microbiol Lett 218 93 99 10.1111/j.1574-6968.2003.tb11503.x 12583903 10.1111/j.1574-6968.2003.tb11503.x 1:CAS:528:DC%2BD3sXhtVGjsrg%3D
    • (2003) FEMS Microbiol Lett , vol.218 , pp. 93-99
    • Grant, A.W.1    Steel, G.2    Waugh, H.3    Ellis, E.M.4
  • 69
    • 0028939260 scopus 로고
    • Glyoxalase III from Escherichia coli: A single novel enzyme for the conversion of methylglyoxal into D-lactate without reduced glutathione
    • 7848303 1:CAS:528:DyaK2MXjsFyhtbY%3D
    • K Misra AB Banerjee S Ray M Ray 1995 Glyoxalase III from Escherichia coli: a single novel enzyme for the conversion of methylglyoxal into D-lactate without reduced glutathione Biochem J 305 999 1003 7848303 1:CAS:528: DyaK2MXjsFyhtbY%3D
    • (1995) Biochem J , vol.305 , pp. 999-1003
    • Misra, K.1    Banerjee, A.B.2    Ray, S.3    Ray, M.4
  • 70
    • 0028786475 scopus 로고
    • Potassium channel activation by glutathione-s-conjugates in Escherichia coli: Protection against methylglyoxal is mediated by cytoplasmic acidification
    • 10.1111/j.1365-2958.1995.mmi-17061025.x 8594323 10.1111/j.1365-2958.1995. mmi-17061025.x 1:CAS:528:DyaK2MXptVKmsLg%3D
    • GP Ferguson D McLaggan IR Booth 1995 Potassium channel activation by glutathione-s-conjugates in Escherichia coli: protection against methylglyoxal is mediated by cytoplasmic acidification Mol Microbiol 17 1025 1033 10.1111/j.1365-2958.1995.mmi-17061025.x 8594323 10.1111/j.1365-2958.1995.mmi- 17061025.x 1:CAS:528:DyaK2MXptVKmsLg%3D
    • (1995) Mol Microbiol , vol.17 , pp. 1025-1033
    • Ferguson, G.P.1    McLaggan, D.2    Booth, I.R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.