The effect of combined clopidogrel and aspirin therapy after off-pump coronary surgery: A pilot study

Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery

Volumn 4, Issue 5, 2009, Pages 265-268

  Mujanovic, Emir ^a,b,c   Nurkic, Midhat ^a,c   Caluk, Jasmin ^a,b,c   Terzic, Ibrahim ^a,b,c   Kabil, Emir ^a,b,c   Bergsland, Jacob ^a,b,d  

^a University Clinical Medical Center   (Bosnia and Herzegovina)

^b BH Heart Center Tuzla   (Bosnia and Herzegovina)

^c Tuzla University   (Bosnia and Herzegovina)

^d OSLO UNIVERSITY HOSPITAL   (Norway)

Author keywords

Aspirin; CABG; Clopidogrel.; Graft patency

Indexed keywords

ACETYLSALICYLIC ACID; CLOPIDOGREL; CREATINE KINASE MB;

ADD ON THERAPY; ADULT; ANASTOMOSIS; ANGIOCARDIOGRAPHY; ARTICLE; ARTIFICIAL VENTILATION; BLOOD TRANSFUSION; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG EFFICACY; DRUG SAFETY; GRAFT PATENCY; HEART ATRIUM FIBRILLATION; HEMATOCRIT; HUMAN; INTENSIVE CARE UNIT; LENGTH OF STAY; OFF PUMP CORONARY SURGERY; OPERATION DURATION; PERIOPERATIVE PERIOD; PILOT STUDY; POSTOPERATIVE CARE; POSTOPERATIVE COMPLICATION; POSTOPERATIVE HEMORRHAGE; PRIORITY JOURNAL; PROSPECTIVE STUDY; RANDOMIZED CONTROLLED TRIAL; STERNOTOMY; SURGICAL MORTALITY; SURGICAL RISK; TREATMENT DURATION; VEIN GRAFT;

EID: 70349690638     PISSN: 15569845     EISSN: 15590879     Source Type: Journal    
DOI: 10.1097/IMI.0b013e3181bbc754     Document Type: Article

References (22)

1. Puskas JD. Off-pump versus conventional coronary artery bypass grafting. Innovations. 2005;1:3-27.
2. Bergsland J, Hasnain S, Lajos TZ, Salerno TA. Elimination of cardiopulmonary bypass: a prime goal in reoperative coronary artery bypass surgery. Eur J Cardiothorac Surg. 1998;14:59-62; discussion 62-153
3. Bergsland J, Hasnan S, Lewin AN, et al. Coronary artery bypass grafting without cardiopulmonary bypass-an attractive alternative in high risk patients. Eur J Cardiothorac Surg. 1997;11:876-880.
4. Calafiore AM, Angelini GD, Bergsland J, Salerno TA. Minimally invasive coronary artery bypass grafting. Ann Thorac Surg. 1996;62: 1545-1548.
5. FitzGibbon GM, Burton JR, Leach AJ. Coronary bypass graft fate: angiographic grading of 1400 consecutive grafts early after operation and of 1132 after one year. Circulation. 1978;57:1070-1074.
6. FitzGibbon GM, Leach AJ, Keon WJ, et al. Coronary bypass graft fate. Angiographic study of 1,179 vein grafts early, one year, and five years after operation. J Thorac Cardiovasc Surg. 1986;91:773-778.
7. Goldman S, Copeland J, Moritz T, et al. Improvement in early saphe-nous vein graft patency after coronary artery bypass surgery with antiplatelet therapy: results of a Veterans Administration Cooperative Study. Circulation. 1988;77:1324-1332.
8. Chesebro JH, Fuster V, Pugo FJ. Aspirin and mortality from coronary bypass surgery. N Engl J Med. 2003;348:1057-1059; author reply 1057-1059.
9. Bergsland J, Karamanoukian HL, Soltoski PR, Salerno TA. "Single suture" for circumflex exposure in off-pump coronary artery bypass grafting. Ann Thorac Surg. 1999;68:1428-1430.
10. Vavuranakis M, Latsios G, Aggelis D, et al. Randomized comparison of the effects of ASA plus clopidogrel versus ASA alone on early platelet activation in acute coronary syndromes with elevated high-sensitivity C-reactive protein and soluble CD40 ligand levels. Clin Ther. 2006;28: 860-871.
11. A randomised, blinded, trial of clopidogrel versus aspirin in patients at risk of ischaemic events (CAPRIE). CAPRIE Steering Committee. Lancet. 1996;348:1329-1339.
12. Hacke W. From CURE to MATCH: ADP receptor antagonists as the treatment of choice for high-risk atherothrombotic patients. Cerebrovasc Dis. 2002;13(Suppl 1):22-26.
13. Yusuf S, Zhao F, Mehta SR, et al. Effects of clopidogrel in addition to aspirin in patients with acute coronary syndromes without ST-segment elevation. N Engl J Med. 2001;345:494-502.
14. Helgason CM, Bolin KM, Hoff JA, et al. Development of aspirin resistance in persons with previous ischemic stroke. Stroke. 1994;25: 2331-2336.
15. Harker LA, Marzec UM, Kelly AB, et al. Clopidogrel inhibition of stent, graft, and vascular thrombogenesis with antithrombotic enhancement by aspirin in nonhuman primates. Circulation. 1998;98:2461-2469.
16. Easton JD. Future perspectives for optimizing oral antiplatelet therapy. Cerebrovasc Dis. 2001;11(Suppl 2):23-28.
17. Bhatt DL, Chew DP, Hirsch AT, et al. Superiority of clopidogrel versus aspirin in patients with prior cardiac surgery. Circulation. 2001;103: 363-368.
18. Gundry SR, Romano MA, Shattuck OH, et al. Seven-year follow-up of coronary artery bypasses performed with and without cardiopulmonary bypass. J Thorac Cardiovasc Surg. 1998;115:1273-1277; discussion 1277-1278.
19. Khan NE, De Souza A, Mister R, et al. A randomized comparison of off-pump and on-pump multivessel coronary-artery bypass surgery. N Engl J Med. 2004;350:21-28.
20. Lingaas PS, Hol PK, Lundblad R, et al. Clinical and angiographic outcome of coronary surgery with and without cardiopulmonary bypass: a prospective randomized trial. Heart Surg Forum. 2004;7:37-41.
21. Hol PK, Fosse E, Mork BE, et al. Graft control by transit time flow measurement and intraoperative angiography in coronary artery bypass surgery. Heart Surg Forum. 2001;4:254-257; discussion 257-258.
22. Kapetanakis EI, Medlam DA, Petro KR, et al. Effect of clopidogrel premedication in off-pump cardiac surgery: are we forfeiting the benefits of reduced hemorrhagic sequelae? Circulation. 2006;113:1667-1674.