Baclofen, raclopride, and naltrexone differentially affect intake of fat and sucrose under limited access conditions

Behavioural Pharmacology

Volumn 20, Issue 5-6, 2009, Pages 537-548

  Corwin, Rebecca L ^a   Wojnicki, Francis H ^a  

^a PENNSYLVANIA STATE UNIVERSITY   (United States)

Author keywords

Behavioral models; Binge eating; Bulimia; Dopamine; Eating disorders; Food intake; GABA; Ingestive behavior; Opioids; Reward

Indexed keywords

4 AMINOBUTYRIC ACID B RECEPTOR; 8 CHLORO 2,3,4,5 TETRAHYDRO 3 METHYL 5 PHENYL 1H 3 BENZAZEPIN 7 OL HYDROGEN MALEATE; BACLOFEN; DOPAMINE 1 RECEPTOR; DOPAMINE 2 RECEPTOR; NALTREXONE; OPIATE RECEPTOR; RACLOPRIDE;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; FAT INTAKE; MALE; NONHUMAN; RAT; SUGAR INTAKE;

ANALYSIS OF VARIANCE; ANIMALS; BACLOFEN; BENZAZEPINES; CONDITIONING, OPERANT; DOPAMINE ANTAGONISTS; DOSE-RESPONSE RELATIONSHIP, DRUG; EATING; FATS; FEEDING BEHAVIOR; FOOD PREFERENCES; GABA AGONISTS; MALE; NALTREXONE; NARCOTIC ANTAGONISTS; RACLOPRIDE; RATS; RATS, SPRAGUE-DAWLEY; REINFORCEMENT SCHEDULE; SUCROSE; SWEETENING AGENTS;

EID: 70349683205     PISSN: 09558810     EISSN: None     Source Type: Journal    
DOI: 10.1097/FBP.0b013e3283313168     Document Type: Article

References (55)

1. APA (American Psychiatric Association) (2000). Diagnostic and Statistical Manual-IV-Text Revision.Washington, DC: American Psychiatric Association; pp. 589-595
2. online BED. Avena NM, Rada P, Moise N, Hoebel BG (2006). Sucrose sham feeding on a binge schedule releases accumbens dopamine repeatedly and eliminates the acetylcholine satiety response. Neurosci 139:813-820
3. Avena NM, Rada P, Hoebel BG (2008). Underweight rats have enhanced dopamine release and blunted acetylcholine response in the nucleus accumbens while bingeing on sucrose. Neuroscience 156:865-871
4. Baker RW, Osman JJ, Bodnar RJ (2001). Differential actions of dopamine receptor antagonism in rats upon food intake elicited by either mercaptoacetate or exposure to a palatable high-fat diet. Pharmacol Biochem Behav 69:201-208
5. Boggiano MM, Chandler PC, Viana JB, Oswald KD, Maldonado CD,Wauford PK (2005). Combined dieting and stress evoke exaggerated responses to opioids in binge-eating rats. Behav Neurosci 119:1207-1214
6. Brebner K, Phelan R, Roberts DCS (2000). Effect of baclofen on cocaine selfadministration in rats reinforced under fixed-ratio 1 and progressive ratio schedules. Physchopharmacology 148:314-321
7. Brewer JA, Potenza MN (2008). The neurobiology and genetics of impulse control disorders: relationships to drug addictions. Biochem Pharmacol 75:63-75
8. Broft AT, Spanos A, Corwin RLW, Mayer L, Steinglass J, Devlin MJ, Attia E,Walsh BT (2007). Baclofen for binge eating: an open-label trial. Int J Eat Disord 40:687-691
9. Buda-Levin A, Wojnicki FHE, Corwin RL (2005). Baclofen reduces fat intake under binge-type conditions. Physiol Behav 86:176-184
10. Colantuoni C, Schwenker J, McCarthy J, Rada P, Ladenheim B, Cadet JL, et al. (2001). Excessive sugar intake alters binding to dopamine and mu-opioid receptors in the brain. NeuroReport 12:3549-3552
11. Collins GT, Calinski DM, Newman AH, Grundt P, Woods JH (2008). Food restriction alters N0-propyl-4,5,6,7-tetrahydrobenzothiazole-2,6-diamine dihydrochloride (pramipexole)-induced yawning, hypothermia, and locomotor activity in rats: evidence for sensitization of dopamine D2 receptor-mediated effects. J Pharmacol Exp Ther 325:691-697
12. Corwin RL (2004). Binge-type eating induced by limited access in rats does not require energy restriction on the previous day. Appetite 42:139-142
13. Corwin RL,Wojnicki FHE, Fisher JO, Dimitriou SG, Rice HB, Young MA (1998). Limited access to a dietary fat option affects ingestive behavior but not body composition in male rats. Physiol Behav 65:545-553
14. Corwin RL, Buda-Levin A (2004). Behavioral models of binge-type eating. Physiol Behav 82:123-130
15. Czachowski CL, Legg BH, Stansfield KH (2006). Ethanol and sucrose seeking and consumption following repeated administration of the GABA(B) agonist baclofen in rats. Alcohol Clin Exp Res 30:812-818
16. Davis JF, Melhorn SJ, Shurdan JD, Heiman JU, Tschop MH, Clegg DJ, Benoit SC (2007). Comparison of hydrogenated vegetable shortening and nutritionally complete high-fat diet on limited access-binge behavior in rats. Physiol Behav 92:924-930
17. Dimitriou SG, Rice HB, Corwin RL (2000). Effects of limited access to a fat option on food intake and body composition in female rats. Int J Eat Disord 28:436-445
18. Drewnowski A, Krahn DD, Demitrack MA, Nairn K, Gosnell BA (1995). Naloxone, an opiate blocker, reduces the consumption of sweet high-fat foods in obese and lean female binge eaters. Am J Clin Nutr 61:1206-1212
19. Ebenezer IS (1995). Intraperitoneal administration of baclofen increases consumption of both solid and liquid diets in rats. Euro J Pharmacol 273:183-185
20. Ebenezer IS, Patel SM (2004). Effects of the GABAB receptor agonists baclofen and 3-aminopropylphosphinic acid (3-APA) on food intake in rats. Methods Find Exp Clin Pharmacol 26:627-630
21. Ebenezer IS, Pringle AK (1992). The effect of systemic administration of baclofen on food intake in rats. Neuropharmacology 31:39-42
22. Elsworth JD, Roth RH (1997). Dopamine autoreceptor pharmacology and function. In: Neve KA, Neve RL, editors. The Dopamine Receptors. Totowa, NJ: Humana Press; pp. 223-265
23. Fiorillo CD, Tobler PN, Schultz W (2003). Discrete coding of reward probability and uncertainty by dopamine neurons. Science 299:1898-1902
24. Hagan MM, Holguin FD, Cabello CE, Hanscom DR, Moss DE (1997). Combined naloxone and fluoxetine on deprivation-induced binge eating of palatable foods in rats. Pharmacol Biochem Behav 58:1103-1107
25. Hajnal A, Norgren R (2002). Repeated access to sucrose augments dopamine turnover in the nucleus accumbens. Neuroreport 13:2213-2216 (Pubitemid 36044431)
26. Hajnal A, Norgren R (2005). Taste pathways that mediate accumbens dopamine release by sapid sucrose. Physiol Behav 84:363-369
27. Hajnal A, Smith GP, Norgren R (2004). Oral sucrose stimulation increases accumbens dopamine in the rat. Am J Physiol Regul Integr Comp Physiol 286:R31-R37
28. Halmi KA, Agras WS, Mitchell J, Wilson GT, Crow S, Bryson SW, Kraemer H (2002). Relapse predictors of patients with bulimia nervosa who achieved abstinence through cognitive behavioral therapy. Arch Gen Psychiatry 59:1105-1109
29. Heusner AA (1985). Body size and energy metabolism. Ann Rev Nutr 5:267-293
30. Higgs S, Barber DJ (2004). Effects of baclofen on feeding behavior examined in the runway. Prog Neuropsychopharmacol Biol Psychiatry 28:405-408
31. Hudson JI, Hiripi E, Pope HG Jr, Kessler RC (2007). The prevalence and correlates of eating disorders in the National Comorbidity Survey replication. Biol Psychiatry 61:348-358
32. Hull LC, Pitts GC (1971). Gastric capacity and energy absorption in the force-fed rat. J Nutr 101:593-596
33. Islam AK, Bodnar RJ (1990). Selective opioid receptor antagonist effects upon intake of a high-fat diet in rats. Brain Research 508:293-296
34. Janak PH, Gill TM (2003). Comparison of the effect of allopregnanolone with direct GABAergic agonists on ethanol self-administration with and without concurrently available sucrose. Alcohol 30:1-7
35. Jimerson DC, Lesem MD, Kaye WH, Brewerton TD (1992). Low serotonin and dopamine metabolite concentrations in cerebrospinal fluid from bulimic patients with frequent binge episodes. Arch Gen Psychiatry 49:132-138
36. Kales EF (1990). Macronutrient analysis of binge eating in bulimia. Physiol Behav 48:837-840
37. Kelley AE, Baldo BA, Pratt WE, Will MJ (2005). Cortico-hypothalamic circuitry and food motivation: integration of energy, action, and reward. Physiol Behav 86:773-795
38. Kirkham TC, Barber DJ, Heath RW, Cooper SJ (1987). Differential effects of CGS 8216 and naltrexone on ingestional behaviour. Pharmacol Biochem Behav 26:145-151
39. Koob GF, Le Moal M (2008). Addiction and the brain antireward system. Annu Rev Psychol 59:29-53
40. Lapish CC, Kroener S, Durstewitz D, Lavin A, Seamans JK (2007). The ability of the mesocortical dopamine system to operate in distinct temporal modes. Psychopharmacology (Berl) 191:609-625
41. Levine AS, Kotz CM, Gosnell BA (2003). Sugars and fats: the neurobiology of preference. J Nutr 133:831S-834S
42. Liang NC, Hajnal A, Norgren R (2006). Sham feeding corn oil increases accumbens dopamine in the rat. Am J Physiol Regul Integr Comp Physiol 291:R1236-R1239
43. Maccioni P, Serra S, Vaca G, Orru A, Pes D, Agabio R, Addolorato G, et al. (2005). Baclofen-induced reduction of alcohol reinforcement in alcoholpreferring rats. Alcohol 36:161-168
44. Maccioni P, Fantini N, Froestl W, Carai MA, Gessa GL, Colombo G (2008). Specific reduction of alcohol's motivational properties by the positive allosteric modulator of the GABAB receptor, GS39783 - comparison with the effect of the GABAB receptor direct agonist, baclofen. Alcohol Clin Exp Res 32:1558-1564
45. McKinney WT Jr (1974). Animal models in psychiatry. Perspect Biol Med 17:529-542
46. Maldonado-Irizarry CS, Swanson CJ, Kelley AE (1995). Glutamate receptors in the nucleus accumbens shell control feeding behavior via the lateral hypothalamus. J Neurosci 15:6779-6788
47. Marks-Kaufman R, Kanarek RB (1980). Morphine selectively influences macronutrient intake in the rat. Pharmacol Biochem Behav 12:427-430
48. Melis M, Camarini R, Ungless MA, Bonci A (2002). Long-lasting potentiation of GABAergic synapses in dopamine neurons after a single in vivo ethanol exposure. J Neurosci 22:2074-2082
49. Mizushige T, Matsumura S, Yoneda T, Tsuzuki S, Inoue K, Fushiki T (2006). Daily increase of fat ingestion mediated via mu-opioid receptor signaling pathway. Biomed Res 6:259-263
50. Patel SM, Ebenezer IS (2008). The effects of chronic intraperitoneal administration of the GABAB receptor agonist baclofen on food intake in rats. Eur J Pharmacol 593:68-72
51. Petry NM (1997). Benzodiazepine-GABA modulation of concurrent ethanol and sucrose reinforcement in the rat. Exp Clin Psychopharm 5:183-194
52. Phillips G, Willner P, Muscat R (1991a). Suppression or facilitation of operant behaviour by raclopride dependent on concentration of sucrose reward. Psychopharm 105:239-246
53. Phillips G, Willner P, Muscat R (1991b). Reward-dependent suppression or facilitation of consummatory behaviour by raclopride. Psychopharm 105:355-360
54. Rada P, Avena NM, Hoebel BG (2005). Daily bingeing on sugar repeatedly releases dopamine in the accumbens shell. Neuroscience 134:737-744
55. Rao RE, Wojnicki FHE, Coupland J, Ghosh S, Corwin RLW (2008). Baclofen, raclopride and naltrexone differentially reduce solid fat emulsion intake under limited access conditions. Pharmacol Biochem Behav 89:581-590