The role of CD4 and CD8 lymphocytes and macrophages in psoriasis vulgaris

Acta Dermatovenerologica Croatica

Volumn 17, Issue 3, 2009, Pages 162-165

  Čabrijan, Leo ^a   Lipozenčić, Jasna ^b   Batinac, Tanja ^a   Peternel, Sandra ^a   Paštar, Zrinjka ^b  

^a UNIVERSITY OF RIJEKA   (Croatia)

^b UNIVERSITY OF ZAGREB   (Croatia)

Author keywords

CD4; CD8; Macrophages; Psoriasis vulgaris

Indexed keywords

ARTICLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CONTROLLED STUDY; DERMIS; EPIDERMIS; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOPATHOGENESIS; MACROPHAGE; PSORIASIS VULGARIS; SKIN DEFECT;

CASE-CONTROL STUDIES; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CELL COUNT; HUMANS; IMMUNOHISTOCHEMISTRY; MACROPHAGES; PSORIASIS;

EID: 70349669145     PISSN: 1330027X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (20)

1. Pašić A. Eritematoskvamozne i papulozne dermatoze. In: Lipozeňić J, et al. Dermatovenerologija. Zagreb: Medicinska naklada; 2004. pp. 197-207.
2. Springer TA. Adhesion receptors of the immune system. Nature 1990;346:425-434
3. Hisashi W, Masahiro T. E-selectin and vascular cell adhesion molecule-1 are critical for initial trafficking of helper-inducer/memory T cells in psoriatic plaques. Arch Derm 1994;130:457-463
4. Duvic M, Asanao A, Hager C, Mays S. The pathogenesis of psoriasis and the mechanism of action of tazarotene. J Am Acad Dermatol 1998;39:S129-32. (Pubitemid 28485162)
5. Asadullah K, Döcke WD, Ebeling M, Friedrich M, Belbe G, Audring H. Interleukin 10 treatment of psoriasis: clinical results of a phase 2 trial. Arch Dermatol 1999;135:187-192 (Pubitemid 29098366)
6. Asadullah K, Sterry W, Stephanek K, Jasulaitis D, Leupold M, Audring H, et al. IL-10 is a key cytokine in psoriasis. Proof of principle by IL-10 therapy: a new therapeutic approach. J Clin Invest 1998;101:783-794
7. Boehm U, Klamp T, Groot M, Howard JC. Cellular responses to interferon-gamma. Annu Rev Immunol 1997;15:749-795
8. Rottman J, Smith T, Ganley K, Kikuchi T, Krueger J. Potential role of the chemokine receptors CXCR3 CCR4 and the integrin alfaEbeta7 in the pathogenesis of psoriasis vulgaris. Lab Invest 2001;81:335-347 (Pubitemid 32245066)
9. Čabrijan L, Batinac T, Lenković M, Gruber F. The distinction between lesional and non-lesional skin in psoriasis vulgaris through expression of adhesion molecules ICAM-1 and VCAM-1. Med Hypotheses 2009;72:327-329 Epub 2008. Nov 20.
10. Čabrijan L, Lipozenčić J, Batinac T, Lenković M, Stanić Zgombić Z. Influence of PUVA and UVB radiation on expression of ICAM-1 nad VCAM-1 molecules in psoriasis vulgaris. Coll Antropol 2008;32 Suppl 2:53-56
11. Vissers WM, Arndtz CHM, Muys L, Van Erp PEJ, Jong EMG, van de Kerkohf PCM. Memory effector (CD45RO+) and cytotoxic CD8+ T cells appear early in the margin zone of spreading psoriatic lesions in contrast to cells expressing natural killer receptors, which appear late. Br J Dermatol 2004;150:852-859 (Pubitemid 38903516)
12. de Boer OJ, Visser C, Bos A, Pranab K. Cellular interactions and adhesion molecules in psoriatic skin. Acta Derm Venereol Suppl (Stockh) 1994;186:15-18 (Pubitemid 24208139)
13. Onuma S. Immunohistochemical studies of in- filtrating cells in early and chronic lesions of psoriasis. J Dermatol 1994;21:223-232 (Pubitemid 24187009)
14. Nakamura K, Yasaka N, Asahina A, Kato M, Miyazuno K, Furue M, et al. Increased numbers of CD68 antigen positive dendritic epidermal cells and upregulation of CLA (cutaneous lymphocyte-associated antigen) expression on these cells in various skin diseases. J Dermatol Sci 1998;18:170-180 (Pubitemid 28539433)
15. Deguchi M, Aiba S, Ohtani H, Nagura H, Tagami H. Comparison of the distribution and numbers of antigen-presenting cells among T lymphocyte-mediated dermatoses: CD1a+, factor XIIIa+, and CD68+ cells in eczematous dermatitis, psoriasis, lichen planus and graft-versus-host disease. Arch Dermatol Res 2002;294:297-302.
16. Koga T, Duan H, Urabe K, Furue M. In situ localization of CD83-positive dendritic cells in psoriatic lesions. Dermatology 2002;204:100-103
17. Zhu Kj, Cheng H, Mao Xh, Lao LM, Cen JP, Ye J. Increased endocytic activity in monocytederived dendritic cells in patients with psoriasis vulgaris. Indian J Med Res 2006;123:43-50.
18. Chamian F, Krueger JG. Psoriasis vulgaris: an interplay of T lymphocytes, dendritic cells, and inflammatory cytokines in pathogenesis. Curr Opin Rheumatol 2004;16:331-337
19. Chen J, Tan Z, Liu Z, Wu Y, Li J. Expression of plasmacytoid dendritic cells, IRF-7, IF-Nalpha mRNA in the lesions of psoriasis vulgaris. J Huazhong Univ Sci Technol Med Sci 2006;26:747-759
20. Jariwala SP. The role of dendritic cells in the immunopathogenesis of psoriasis. Arch Dermatol Res 2007;299:359-366 (Pubitemid 47383849)