Carbapenem-resistant Enterobacter cloacae and the emergence of metallo-β-lactamase-producing strains in a third-level hospital (Santiago de Compostela, NW Spain)

European Journal of Clinical Microbiology and Infectious Diseases

Volumn 28, Issue 10, 2009, Pages 1253-1258

  Trevino M ^a   Moldes, L ^a   Martinez Lamas L ^a   Varon C ^a   Regueiro, B J ^a  

^a Instituto de Salud Carlos III   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

AMIKACIN; CARBAPENEM; CARBAPENEMASE; CEFEPIME; CEFOTAXIME; CEFTRIAXONE; CIPROFLOXACIN; CLAVULANIC ACID; ERTAPENEM; GENTAMICIN; IMIPENEM; MEROPENEM; METALLO BETA LACTAMASE; PIPERACILLIN PLUS TAZOBACTAM; TIGECYCLINE; TOBRAMYCIN;

ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; ENTEROBACTER CLOACAE; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; GENOTYPE; HUMAN; KLEBSIELLA PNEUMONIAE; MALE; MINIMUM INHIBITORY CONCENTRATION; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEUS MIRABILIS; SPECIES IDENTIFICATION;

ANTI-BACTERIAL AGENTS; BACTERIAL PROTEINS; BETA-LACTAM RESISTANCE; BETA-LACTAMASES; CARBAPENEMS; CROSS INFECTION; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG RESISTANCE, MULTIPLE, BACTERIAL; ENTEROBACTER CLOACAE; ENTEROBACTERIACEAE INFECTIONS; GENE AMPLIFICATION; GENOTYPE; HUMANS; MICROBIAL SENSITIVITY TESTS; POLYMERASE CHAIN REACTION; SPAIN;

EID: 70349665268     PISSN: 09349723     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10096-009-0765-x     Document Type: Article

References (32)

1. DL Paterson RA Bonomo 2005 Extended-spectrum β-lactamases: a clinical update Clin Microbiol Rev 18 657 686 10.1128/CMR.18.4.657-686.2005 16223952 10.1128/CMR.18.4.657-686.2005 1:CAS:528:DC%2BD2MXht1Wrsr%2FE (Pubitemid 41504510)
2. G Cornaglia M Akova G Amicosante R Cantón R Cauda JD Docquier M Edelstein JM Frère M Fuzi M Galleni H Giamarellou M Gniadkowski R Koncan B Libisch F Luzzaro V Miriagou F Navarro P Nordmann L Pagani L Peixe L Poirel M Souli E Tacconelli A Vatopoulos GM Rossolini ESCMID Study Group for Antimicrobial Resistance Surveillance (ESGARS) 2007 Metallo-β-lactamases as emerging resistance determinants in Gram-negative pathogens: open issues Int J Antimicrob Agents 29 380 388 10.1016/j.ijantimicag.2006.10.008 17223319 10.1016/j.ijantimicag.2006.10.008 1:CAS:528:DC%2BD2sXislehs7c%3D (Pubitemid 46349587)
3. TR Walsh MA Toleman L Poirel P Nordmann 2005 Metallo-β-lactamases: the quiet before the storm? Clin Microbiol Rev 18 306 325 10.1128/CMR.18.2.306- 325.2005 15831827 10.1128/CMR.18.2.306-325.2005 1:CAS:528:DC%2BD2MXksVymtb0%3D (Pubitemid 40548296)
4. P Nordmann L Poirel 2002 Emerging carbapenemases in Gram-negative aerobes Clin Microbiol Infect 8 321 331 10.1046/j.1469-0691.2002.00401.x 12084099 10.1046/j.1469-0691.2002.00401.x 1:CAS:528:DC%2BD38XlvVKntb4%3D (Pubitemid 34993804)
5. EH Lee MH Nicolas MD Kitzis G Pialoux E Collatz L Gutmann 1991 Association of two resistance mechanisms in a clinical isolate of Enterobacter cloacae with high-level resistance to imipenem Antimicrob Agents Chemother 35 1093 1098 1929248 1:CAS:528:DyaK3MXksVGqt70%3D
6. BA Rasmussen K Bush D Keeney Y Yang R Hare C O'Gara AA Medeiros 1996 Characterization of IMI-1 beta-lactamase, a class A carbapenem-hydrolyzing enzyme from Enterobacter cloacae Antimicrob Agents Chemother 40 2080 2086 8878585 1:CAS:528:DyaK28XlsVChtr4%3D
7. LM Deshpande RN Jones TR Fritsche HS Sader 2006 Occurrence and characterization of carbapenemase-producing Enterobacteriaceae: report from the SENTRY Antimicrobial Surveillance Program (2000-2004) Microb Drug Resist 12 223 230 10.1089/mdr.2006.12.223 17227206 10.1089/mdr.2006.12.223 1:CAS:528:DC%2BD2sXlt12gsw%3D%3D (Pubitemid 46110652)
8. M Tato TM Coque P Ruíz-Garbajosa V Pintado J Cobo HS Sader RN Jones F Baquero R Cantón 2007 Complex clonal and plasmid epidemiology in the first outbreak of Enterobacteriaceae infection involving VIM-1 metallo-β-lactamase in Spain: toward endemicity? Clin Infect Dis 45 1171 1178 10.1086/522288 17918078 10.1086/522288 1:CAS:528:DC%2BD2sXht1ykt7jO (Pubitemid 47580315)
9. Clinical Laboratory Standards Institute (CLSI) (2008) Performance standards for antimicrobial susceptibility testing. Eighteenth informational supplement, M100-S18. CLSI, Wayne, PA
10. K Lee Y Chong HB Shin YA Kim D Yong JH Yum 2001 Modified Hodge and EDTA-disk synergy tests to screen metallo-β-lactamase-producing strains of Pseudomonas and Acinetobacter species Clin Microbiol Infect 7 88 91 10.1046/j.1469-0691.2001.00204.x 11298149 10.1046/j.1469-0691.2001.00204.x 1:CAS:528:DC%2BD3MXjtl2jur0%3D (Pubitemid 34960278)
11. J-J Yan P-R Hsueh W-C Ko K-T Luh S-H Tsai H-M Wu J-J Wu 2001 Metallo-β-lactamases in clinical Pseudomonas isolates in Taiwan and identification of VIM-3, a novel variant of the VIM-2 enzyme Antimicrob Agents Chemother 45 2224 2228 10.1128/AAC.45.8.2224-2228.2001 11451678 10.1128/AAC.45.8.2224-2228.2001 1:CAS:528:DC%2BD3MXlsVCqsr0%3D (Pubitemid 32664460)
12. B Anderson S Nicholas B Sprague J Campos B Short N Singh 2008 Molecular and descriptive epidemiology of multidrug-resistant Enterobacteriaceae in hospitalized infants Infect Control Hosp Epidemiol 29 250 255 10.1086/527513 18251685 10.1086/527513 (Pubitemid 351269191)
13. Visser CE, de Wever B, Rijnsburger M, Spanjaard L, van Toledo L, Savelkoul P Duim B (2008) Diversilab typing for management of Enterobacter cloacae outbreaks at a neonatal ICU. In: Proceedings of the 18th European Congress Clinical Microbiology and Infectious Diseases (ECCMID), Barcelona, Spain, April 2008, abstract no. P1682
14. AN Stumpf A Roggenkamp H Hoffmann 2005 Specificity of enterobacterial repetitive intergenic consensus and repetitive extragenic palindromic polymerase chain reaction for the detection of clonality within the Enterobacter cloacae complex Diagn Microbiol Infect Dis 53 9 16 10.1016/j.diagmicrobio.2005.04.003 16182074 10.1016/j.diagmicrobio.2005.04.003 1:CAS:528:DC%2BD2MXhtVegurfE (Pubitemid 41337992)
15. V Miriagou E Tzelepi D Gianneli LS Tzouvelekis 2003 Escherichia coli with a self-transferable, multiresistant plasmid coding for metallo-β-lactamase VIM-1 Antimicrob Agents Chemother 47 395 397 10.1128/AAC.47.1.395-397.2003 12499222 10.1128/AAC.47.1.395-397.2003 1:CAS:528:DC%2BD3sXis12luw%3D%3D (Pubitemid 36070394)
16. P Giakkoupi A Xanthaki M Kanelopoulou A Vlahaki V Miriagou S Kontou E Papafraggas H Malamou-Lada LS Tzouvelekis NJ Legakis AC Vatopoulos 2003 VIM-1 metallo-beta-lactamase-producing Klebsiella pneumoniae strains in Greek hospitals J Clin Microbiol 41 3893 3896 10.1128/JCM.41.8.3893-3896.2003 12904412 10.1128/JCM.41.8.3893-3896.2003 1:CAS:528:DC%2BD3sXnt1SktL8%3D (Pubitemid 36994735)
17. A Ikonomidis D Tokatlidou I Kristo D Sofianou A Tsakris P Mantzana S Pournaras AN Maniatis 2005 Outbreaks in distinct regions due to a single Klebsiella pneumoniae clone carrying a bla VIM-1 metallo-{beta}-lactamase gene J Clin Microbiol 43 5344 5347 10.1128/JCM.43.10.5344-5347.2005 16208014 10.1128/JCM.43.10.5344-5347.2005 1:CAS:528:DC%2BD2MXhtFGqt73N (Pubitemid 41484056)
18. S Vourli H Tsorlini H Katsifa M Polemis LS Tzouvelekis A Kontodimou AC Vatopoulos 2006 Emergence of Proteus mirabilis carrying the bla metallo-beta-lactamase gene Clin Microbiol Infect 12 691 694 10.1111/j.1469-0691.2006.01489.x 16774572 10.1111/j.1469-0691.2006.01489.x 1:CAS:528:DC%2BD28XnsVCns78%3D (Pubitemid 43842496)
19. EV Scoulica IK Neonakis AI Gikas YJ Tselentis 2004 Spread of bla(VIM-1)-producing E. coli in a university hospital in Greece. Genetic analysis of the integron carrying the bla(VIM-1) metallo-beta-lactamase gene Diagn Microbiol Infect Dis 48 167 172 10.1016/j.diagmicrobio.2003.09.012 15023424 10.1016/j.diagmicrobio.2003.09.012 1:CAS:528:DC%2BD2cXitFCiu7s%3D (Pubitemid 38340515)
20. I Galani M Souli Z Chryssouli K Orlandou H Giamarellou 2005 Characterization of a new integron containing bla(VIM-1) and aac(6)-IIc in an Enterobacter cloacae clinical isolate from Greece J Antimicrob Chemother 55 634 638 15761066 10.1093/jac/dki073 1:CAS:528:DC%2BD2MXjvFymtb8%3D (Pubitemid 40691840)
21. I Galani M Souli E Koratzanis G Koratzanis Z Chryssouli H Giamarellou 2007 Emerging bacterial pathogens: Escherichia coli, Enterobacter aerogenes and Proteus mirabilis clinical isolates harbouring the same transferable plasmid coding for metallo-beta-lactamase VIM-1 in Greece J Antimicrob Chemother 59 578 579 10.1093/jac/dkl508 17255145 10.1093/jac/dkl508 1:CAS:528: DC%2BD2sXktlKgtrk%3D (Pubitemid 47073473)
22. N Kassis-Chikhani D Decré V Gautier B Burghoffer F Saliba D Mathieu D Samuel D Castaing JC Petit E Dussaix G Arlet 2006 First outbreak of multidrug-resistant Klebsiella pneumoniae carrying blaVIM-1 and blaSHV-5 in a French university hospital J Antimicrob Chemother 57 142 145 10.1093/jac/dki389 16284103 10.1093/jac/dki389 1:CAS:528:DC%2BD28XisFyrsg%3D%3D (Pubitemid 43057072)
23. MF Lartigue L Poirel P Nordmann 2004 First detection of a carbapenem-hydrolyzing metalloenzyme in an Enterobacteriaceae isolate in France Antimicrob Agents Chemother 48 4929 4930 10.1128/AAC.48.12.4929-4930.2004 15561885 10.1128/AAC.48.12.4929-4930.2004 1:CAS:528:DC%2BD2cXhtVKmt7fN (Pubitemid 39577711)
24. MT Tórtola S Lavilla E Miró JJ González N Larrosa M Sabaté F Navarro G Prats 2005 First detection of a carbapenem-hydrolyzing metalloenzyme in two Enterobacteriaceae isolates in Spain Antimicrob Agents Chemother 49 3492 3494 10.1128/AAC.49.8.3492-3494.2005 16048967 10.1128/AAC.49.8.3492-3494.2005 (Pubitemid 41060602)
25. HK Lee YJ Park JY Kim E Chang SG Cho HS Chae CS Kang 2005 Prevalence of decreased susceptibility to carbapenems among Serratia marcescens, Enterobacter cloacae, and Citrobacter freundii and investigation of carbapenemases Diagn Microbiol Infect Dis 52 331 336 10.1016/j.diagmicrobio.2005.04.012 15994052 10.1016/j.diagmicrobio.2005.04.012 1:CAS:528:DC%2BD2MXhtVWhu7%2FK (Pubitemid 41297572)
26. DL Paterson 2006 Resistance in gram-negative bacteria: Enterobacteriaceae Am J Med 119 S20 S28 10.1016/j.amjmed.2006.03.013 16735147 10.1016/j.amjmed. 2006.03.013 1:CAS:528:DC%2BD28XmvVylsLo%3D (Pubitemid 43776142)
27. M Souli FV Kontopidou E Koratzanis A Antoniadou E Giannitsioti P Evangelopoulou S Kannavaki H Giamarellou 2006 In vitro activity of tigecycline against multiple-drug-resistant, including pan-resistant, gram-negative and gram-positive clinical isolates from Greek hospitals Antimicrob Agents Chemother 50 3166 3169 10.1128/AAC.00322-06 16940120 10.1128/AAC.00322-06 1:CAS:528:DC%2BD28XpsFems7k%3D (Pubitemid 44396429)
28. A Panagiotakopoulou GL Daikos V Miriagou A Loli E Tzelepi LS Tzouvelekis 2007 Comparative in vitro killing of carbapenems and aztreonam against Klebsiella pneumoniae producing VIM-1 metallo-β-lactamase Int J Antimicrob Agents 29 360 362 10.1016/j.ijantimicag.2006.11.004 17223016 10.1016/j.ijantimicag.2006.11.004 1:CAS:528:DC%2BD2sXhvVGgsr8%3D (Pubitemid 46267392)
29. GL Daikos A Panagiotakopoulou E Tzelepi A Loli LS Tzouvelekis V Miriagou 2007 Activity of imipenem against VIM-1 metallo-β-lactamase-producing Klebsiella pneumoniae in the murine thigh infection model Clin Microbiol Infect 13 202 205 10.1111/j.1469-0691.2006.01590.x 17328735 10.1111/j.1469-0691.2006. 01590.x 1:CAS:528:DC%2BD2sXis1SjsL4%3D (Pubitemid 46111617)
30. M Souli FV Kontopidou E Koratzanis A Antoniadou E Giannitsioti P Evangelopoulou S Kannavaki H Giamarellou 2006 In vitro activity of tigecycline against multiple-drug-resistant, including pan-resistant, Gram-negative and Gram-positive clinical isolates from Greek hospitals Antimicrob Agents Chemother 50 3166 3169 10.1128/AAC.00322-06 16940120 10.1128/AAC.00322-06 1:CAS:528:DC%2BD28XpsFems7k%3D (Pubitemid 44396429)
31. A Loli LS Tzouvelekis E Tzelepi A Carattoli AC Vatopoulos PT Tassios V Miriagou 2006 Sources of diversity of carbapenem resistance levels in Klebsiella pneumoniae carrying blaVIM-1 J Antimicrob Chemother 58 669 672 10.1093/jac/dkl302 16870645 10.1093/jac/dkl302 1:CAS:528:DC%2BD28Xotl2lu7Y%3D (Pubitemid 44288137)
32. R Cantón TM Coque F Baquero 2003 Multi-resistant Gram-negative bacilli: from epidemics to endemics Curr Opin Infect Dis 16 315 325 12861084