Are obsessive-compulsive symptom dimensions familial in nonclinical individuals?

Depression and Anxiety

Volumn 26, Issue 10, 2009, Pages 902-908

  Taberner, Joan ^a,b   Fullana, Miquel A ^a,b,c   Caseras, Xavier ^a,c,d   Pertusa, Alberto ^c,e   Bados, Arturo ^f   Van Den Bree, Marianne ^d   Torrubia, Rafael ^a   Mataix Cols, David ^c  

^a UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

^b HOSPITAL DEL MAR   (Spain)

^c KING'S COLLEGE LONDON   (United Kingdom)

^d CARDIFF UNIVERSITY   (United Kingdom)

^e HOSPITAL UNIVERSITARI DE BELLVITGE   (Spain)

^f UNIVERSITY OF BARCELONA   (Spain)

Author keywords

Family studies; Obsessive compulsive disorder (OCD); Obsessive compulsive symptom dimensions

Indexed keywords

ADULT; AGED; ARTICLE; BIVARIATE ANALYSIS; CHILD PARENT RELATION; CONTROLLED STUDY; FAMILY HISTORY; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; MULTIPLE REGRESSION; OBSESSIVE COMPULSIVE DISORDER; PRIORITY JOURNAL; REGRESSION ANALYSIS; SCORING SYSTEM;

ADOLESCENT; ADULT; AGED; CHILD OF IMPAIRED PARENTS; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HEALTH SURVEYS; HUMANS; MALE; MIDDLE AGED; OBSESSIVE-COMPULSIVE DISORDER; PERSONALITY INVENTORY; PSYCHOMETRICS; RISK FACTORS; SEX FACTORS; SPAIN; YOUNG ADULT;

EID: 70349662146     PISSN: 10914269     EISSN: 15206394     Source Type: Journal    
DOI: 10.1002/da.20606     Document Type: Article

References (52)

1. Pauls DL. The genetics of obsessive compulsive disorder: a review of the evidence. Am J Med Genet (Semin Med Genet) 2008;148:133-139. (Pubitemid 351705130)
2. Hettema JM, Neale MC, Kendler KS. A review and meta-analysis of the genetic epidemiology of anxiety disorders. Am J Psychiatry 2001;158:1568-1578. (Pubitemid 32923644)
3. Grabe HJ, Ruhrmann S, Ettelt S, et al. Familiality of obsessive-compulsive disorder in nonclinical and clinical subjects. Am J Psychiatry 2006;163:1986-1992. (Pubitemid 44807791)
4. van Grootheest DS, Cath DC, Beekman AT, et al. Twin studies on obsessive-compulsive disorder: a review. Twin Res Hum Genet 2005;8:450-458. (Pubitemid 41499486)
5. Mataix-Cols D, Rosario-Campos MC, Leckman JF. A multi-dimensional model of obsessive-compulsive disorder. Am J Psychiatry 2005;162:228-238.
6. Leckman JF, Rauch SL, Mataix-Cols D. Symptom dimensions in obsessive-compulsive disorder: implications for the DSM-IV. CNS Spectrums 2007;12:376-387. (Pubitemid 46867552)
7. Bloch MH, Landeros-Weisenberger A, Rosario MC, et al. Meta-analysis of the symptom structure of obsessive-compulsive disorder. Am J Psychiatry 2008;165:1532-1542.
8. Mataix-Cols D, Rauch SL, Baer L, et al. Symptom stability in adult obsessive-compulsive disorder: data from a naturalistic two-year follow-up study. Am J Psychiatry 2002;159:263-268. (Pubitemid 34126904)
9. Rufer M, Grothusen A, Mass R, et al. Temporal stability of symptom dimensions in adult patients with obsessive-compulsive disorder. J Affective Disord 2005;88:99-102. (Pubitemid 41160420)
10. Fullana MA, Tortella-Feliu M, Caseras X, et al. Temporal stability of obsessive-compulsive symptom dimensions in an undergraduate sample: a prospective 2-year follow-up study. Behav Modif 2007;31:815-824.
11. Fullana MA, Mataix-Cols D, Caspi A, et al. Obsessions and compulsions in the community: prevalence, interference, help-seeking, developmental stability and co-occurring psychiatric conditions. Am J Psychiatry. Advance online publication. Retrieved February 2, 2009; doi:10.1176/appi.ajp.2008.08071006.
12. Matsunaga H, Maebayahi K, Hayashida K, et al. Symptom structure in Japanese patients with obsessive-compulsive disorder. Am J Psychiatry 2008;165:251-253.
13. Hasler G, Kazuba D, Murphy DL. Factor analysis of obsessive- compulsive disorder YBOCS SC symptoms and association with 5-HTTLPR SERT polymorphism. Am J Med Genet (Neuropsychiatr Genet) 2006;141B:403-408. (Pubitemid 43872894)
14. Mataix-Cols D, Wooderson S, Lawrence N, et al. Distinct neural correlates of washing, checking, and hoarding symptom dimensions in obsessive-compulsive disorder. Arch Gen Psychiatry 2004;61:564-576. (Pubitemid 38747311)
15. van den Heuvel OA, Remijnse PL, Mataix-Cols D, et al. The major symptom dimensions of obsessive-compulsive disorder are mediated by partially distinct neural systems. Brain. Advance online publication. Retrieved October 24, 2008; doi:10.1093/ brain/awn267.
16. Alsobrook IJ, Leckman JF, Goodman WK, et al. Segregation analysis of obsessive-compulsive disorder using symptom-based factor scores. Am J Med Genet (Neuropsychiatr Genet) 1999;88:669-675.
17. Hanna GL, Himle JA, Curtis GC, et al. A family study of obsessive-compulsive disorder with pediatric probands. Am J Med Genet (Neuropsychiatr Genet) 2005;134B:13-19. (Pubitemid 40411102)
18. Cullen B, Brown HC, Riddle MA, et al. Factor analysis of the yale-brown obsessive compulsive scale in a family study of obsessive-compulsive disorder. Depress Anxiety 2007;24:130-138. (Pubitemid 46516669)
19. Leckman JF, Pauls DL, Zhang H, et al. Obsessive-compulsive symptom dimensions in affected sibling pairs diagnosed with Gilles de la Tourette syndrome. Am J Med Genet (Neuropsychiatr Genet) 2003;116B:60-68. (Pubitemid 37063616)
20. Hasler G, Kazuba D, Murphy DL. Factor analysis of obsessive-compulsive dissorder YBOCS SC symptoms and association with 5-HTTLPR SERT polymorphism. Am J Med Genet (Neuropsychiatr Genet) 2006;141B:403-408. (Pubitemid 43872894)
21. Chacón P, Rosario-Campos MC, Pauls DL, et al. Obsessive-compulsive symptoms in sibling pairs concordant for obsessive-compulsive disorder. Am J Med Genet (Neuropsychiatr Genet) 2007;144B:551-555. (Pubitemid 46983167)
22. Pinto A, Benjamin D, Greenberg MA, et al. Further development of YBOCS dimensions in the OCD. Collaborative Genetics Study: symptoms vs. categories. J Psychr Res 2008;160:83-93.
23. Samuels JF, Bienvenu 3rd OJ, Riddle MA, et al. Hoarding in obsessive compulsive disorder: results from a case-control study. Behav Res Ther 2002;40:517-528.
24. Samuels JF, Bienvenu 3rd OJ, Pinto A, et al. Hoarding in obsessive-compulsive disorder: results from the OCD Collaborative Genetics Study. Behav Res Ther 2007;45:673-686.
25. Pertusa A, Fullana MA, Singh S, et al. Compulsive hoarding: OCD symptom, distinct clinical syndrome, or both? Am J Psychiatry 2008;165:1289-1298.
26. Gibbs NA. Nonclinical populations in research on obsessive-compulsive disorder: a critical review. Clin Psychol Rev 1996;16: 729-773.
27. Rachman S, de Silva P. Abnormal and normal obsessions. Behav Res Ther 1978;16:233-248.
28. Olatunji BO, Williams BJ, Haslam N, et al. The latent structure of obsessive-compulsive symptoms: a taxometric study. Depress Anxiety 2008;25:956-968.
29. Van Grootheest DS, Boomsma D, Hettema JM, et al. Heritability of obsessive-compulsive symptom dimensions. Am J Med Genet (Neuropsychiatr Genet) 2008;147B:473-478.
30. Fullana MA, Tortella-Feliu M, Caseras X, et al. Psychometric properties of the Spanish version of the Obsessive-Compulsive Inventory-revised in a non-clinical sample. J Anxiety Disord 2005;19:893-903. (Pubitemid 41501546)
31. Foa EB, Huppert JD, Leiberg S, et al. The Obsessive- Compulsive Inventory: development and validation of a short version. Psychol Assess 2002;14:485-496. (Pubitemid 35440493)
32. Sulkovski ML, Sorch EA, Geffken GR, et al. Concurrent validity of the Yale-Brown Obsessive-Compulsive-Scale-Symptom Checklist. J Clin Psychol 2008;64:1338-1351.
33. Hu L, Bentler PM. Cutoff criteria for fit indexes in covariance structure analysis: conventional criteria versus new alternatives. Structural Equation Modelling 1999;6:1-55.
34. Sandín B, Chorot P, Lostao L, et al. Escalas panas de afecto positivo y negativo: validación factorial y convergencia transcultural. Psicothema 1999;11:37-51.
35. Watson D, Clark LA, Tellegen A. Development and validation for brief measures of positive and negative affect: the PANAS scales. J Pers Soc Psychol 1988;54:1063-1070.
36. Wang Y, Samuels JF, Chang YC, et al. Gender differences in genetic linkage and association on 11p15 in obsessive-compulsive disorder families. Am J Med Genet (Neuropsychiatr Genet) 2009;150B:33-40.
37. Hanna GL, Tasha EF, Himle JA, et al. Complex segregation analysis of obsessive-compulsive disorder in families with pediatric probands. Hum Hered 2005;60:1-9.
38. Nestadt G, Lan T, Samuels J, et al. Complex segregation analysis provides compelling evidence for a major gene underlying obsessive-compulsive disorder and for heterogeneity by sex. Am J Hum Genet 2000;67:1611-1616.
39. Cohen J. 1977. Statistical Power Analysis for the Behavioral Sciences. Revised edition. New York: Academic Press.
40. Abramowitz JS, Deacon BJ. Psychometric properties and construct validity of the Obsessive-Compulsive Inventory- Revised: replication and extension with a clinical sample. J Anxiety Disord 2006;20:1016-1035.
41. Fullana MA, Mataix-Cols D, Caseras X, et al. High sensitivity to punishment and low impulsivity in obsessive-compulsive patients with hoarding symptoms. Psychiatry Res 2004;129:21-27. (Pubitemid 39585140)
42. Clifford CA, Murray RM, Fulker DW. Genetic and environmental influences on obsessional traits and symptoms. Psychol Med 1984;14:791-800. (Pubitemid 15221250)
43. Jonnal AH, Gardner CO, Prescott CA, et al. Obsessive and compulsive symptoms in a general population sample of female twins. Am J Med Genet 2000;96:791-796. (Pubitemid 32093913)
44. Hasler G, Pinto A, Greenberg BD, et al. Familiality of factor analysis-derived YBOCS dimensions in OCD-affected sibling pairs from the OCD Collaborative Genetics Study. Biol Psychiatry 2007;61:617-625. (Pubitemid 46328863)
45. Baer L. Factor analysis of symptom subtypes of obsessive compulsive disorder and their relation to personality and tic disorders. J Clin Psychiatry 1994;55:18-23. (Pubitemid 24113071)
46. Tukel R, Ertekin E, Batmaz S, et al. Influence of age of onset on clinical features in obsessive-compulsive disorder. Depress Anxiety 2005;21:112-117. (Pubitemid 41040633)
47. Lensi P, Cassano GB, Correddu G, et al. Obsessive-compulsive disorder. Familial-developmental history, symptomatology, comorbidity and course with special reference to gender-related differences. Br J Psychiatry 1996;169:101-107. (Pubitemid 126735376)
48. Ecker W, Gonner S. Incompleteness and harm avoidance in OCD symptom dimensions. Behav Res Ther 2008;46:895-904.
49. Summerfeldt LJ. Understanding and treating incompleteness in obsessive-compulsive disorder. J Clin Psychol 2004;60:1155-1168. (Pubitemid 39392088)
50. Taylor S, Abramowitz JS, McKay D, et al. Do dysfunctional beliefs play a role in all types of obsessive-compulsive disorder? J Anxiety Disord 2006;20:85-97.
51. Steketee G, Frost R. Compulsive hoarding: current status of the research. Clin Psychol Rev 2003;23:905-927. (Pubitemid 37414897)
52. Iervolino AC, Perroud N, Fullana MA, et al. Prevalence and heritability of compulsive hoarding: a twin and genetic association study. Am J Psychiatry 2009. Advance online publication. Retrieved August 17, 2009; doi:10.1176/appi.ajp.2009.08121789.