Effects of interacting variables on the formulation of Alstonia boonei de Wild (Apocynaceae) tablets

Acta Pharmaceutica Sciencia

Volumn 51, Issue 2, 2009, Pages 141-148

  Majekodunmi, S O ^a   Odeku, O A ^a  

^a UNIVERSITY OF IBADAN   (Nigeria)

Author keywords

Alstonia boonei; Binding agents; Direct compression excipients; Pharmaceutical tablets

Indexed keywords

ALSTONIA BOONEI EXTRACT; CALCIUM PHOSPHATE DIBASIC; EXCIPIENT; MICROCRYSTALLINE CELLULOSE; PLANT EXTRACT; POVIDONE; STARCH; UNCLASSIFIED DRUG;

ALSTONIA BOONEI; APOCYNACEAE; ARTICLE; BARK; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; GRANULATION TISSUE; PLANT STEM; QUANTITATIVE ANALYSIS; TABLET FORMULATION;

EID: 70349662056     PISSN: 13072080     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (24)

1. Abbiw, D. (1990) Useful plants of Ghana. Intermediate Technology Publishers and Royal Botanical Gardens, Kew, London. 119.
2. Akin-Ajani, O. D., Itiola, O. A., and Odeku, O. A. (2005). Effects of plantain and corn starches on the mechanical and disintegration properties of paracetamol tablets. AAPS PharmaSciTech, 6: E458-E462.
3. Asuzu, I. U., and Anaga, A. O. (1991) Pharmacological screening of the aqueous extract of Alstonia boonei stem bark. Fitoter, 63:411-417.
4. Awe, S. O., and Opeke, O. O. (1990). Effects of Alstonia congensis on Plasmodium berghei berghei in mice. Fitoter, 61:225-229.
5. Dalziel, J. M. (1937). The useful plants of West Tropical Africa, crown agents, London, 264.
6. Faparusi, S. I., and Bassir, O. (1972). Triterpines from Alstonia boonei. Phytochemistry, 21:3083-3084.
7. rd Ed. ed. by Lachman et al., Lea and Ferbiger, Philadelphia. 297-303.
8. Irvine, F. R. (1961). The woody plants of Ghana, Oxford University Press, London, p. 868.
9. Itiola, O. A., and Pilpel, N. (1986). Tableting characteristics of metronidazole formulations. Int. J. Pharm. 31: 99-105.
10. Itiola, O. A., and Pilpel N. (1996). Effects of interacting variables on the disintegration and dissolution of metronidazole tablets. Pharmazie, 51:987-989.
11. Itiola, O. A. (1990). The effects of interacting variables on the tensile strength of lactose powder and compacts. Polytech. J. Sci. Tech. 1: 7
12. Itiola, O. A. (1991). Compressional characteristics of three starches and the mechanical properties of their tablets. Pharm World J., 8:91-94.
13. Iwu, M. M. (1993). Handbook of African Medicinal Plants, CRC Press, Boca Raton, FL, USA., 116-118.
14. Kweifo-Okai, G., Bird, D., Field, B., Ambrose, R., Carroll, A. R., Smith, P., and Valdes, R. (1995). Anti-inflammatory activity of a Ghanaian herbal preparation III. J. Ethnopharmacol. 46:7-15.
15. Odeku, O. A. and Itiola, O. A. (1998). Evaluation of khaya gum as a binder in a paracetamol tablet formulation. Pharm. Pharmacol. Commun. 4:183-188. (Pubitemid 28192716)
16. Odeku, O. A. and Itiola, O. A. (2003). Effects of interacting variables on the tensile strength and the release properties of paracetamol tablets. Trop. J. Pharm. Res. 2:147-153.
17. Ojewole, J. A. O. (1984). Studies on the pharmacology of echitamine, an alkaloid-from the stem bark of Alstonia boonei L. (Apocynaceae). Int. J. Crude Drug Res. 22: 121-143
18. Olajide, O. A., Awe, S. O., Makinde, J. M., Ekhelar, A. I., Olusola, A., Morebise, O., and Okpako, D. T. (2000). Studies on the anti-inflammatory, antipyretic and analgesic properties of Alstonia boonei stem bark. J. Ethnopharmacol. 71: 179-186. (Pubitemid 30440667)
19. Oliver-Beever, B. (1986). Medicinal plants in tropical west Africa, Cambridge University Press, London, 89-90.
20. Osadebe, P. O. (2002). Antiinflmmatory properties of the root bark of a. boonei. Nig. J. Nat. Prod. Med., 6: 39-41.
21. Perry, L. M., and Metzger, J. (1980). Medicinal plants of East and Southeast Asia. MTT Press. Cambridge, MA. pp. 22.
22. Vasanth, S., Gopal, R.H., Rao, R.H., Rao, R.B. (1990). Plant antimalarial agents. Ind. J. Sci. Res., 49: 68-77
23. Woolfall, R. C. (1964). An approach to product formulation. Soap Perfum Cosmet, 37:965-970.
24. Wright, C. W., Allen, D., Phillipson, J. D., Geoffrey, C. K., Warhurst, D. C., Massiot, G. and Le Men Oliver, L. (1993). Alstonia species. Are they effective in malaria treatment? J. Ethnopharmacol, 40: 41-45.