Intestinal absorption of daphnetin by rats single pass perfusion in situ

Yaoxue Xuebao

Volumn 44, Issue 8, 2009, Pages 922-926

  Du, Qiu ^a   Di, Liu Qing ^a   Shan, Jin Jun ^a   Liu, Tao Shi ^a   Zhang, Xin Zhuang ^a  

^a NANJING UNIVERSITY OF CHINESE MEDICINE   (China)

Author keywords

Absorption mechanism; Absorption site; Daphnetin; In situ rats single pass perfusion model

Indexed keywords

DAPHNETIN; GLYCOPROTEIN P; PHENOLSULFONPHTHALEIN; VERAPAMIL;

ANIMAL TISSUE; ARTICLE; COLON; DRUG ABSORPTION; DRUG DIFFUSION; DRUG STABILITY; DUODENUM; ILEUM; INTESTINE; INTESTINE ABSORPTION; JEJUNUM; NONHUMAN; RAT;

ANIMALS; FEMALE; HYDROGEN-ION CONCENTRATION; INTESTINAL ABSORPTION; MALE; P-GLYCOPROTEIN; PERFUSION; PERMEABILITY; RATS; RATS, SPRAGUE-DAWLEY; UMBELLIFERONES;

EID: 70349658830     PISSN: 05134870     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (11)

1. Schurgers N, Bijdendijk J, Tukker JJ, et al. Comparison of four experimental techniques for studying drug absorption kinetics in anesthetized rat in situ [J]. J Pharm Sci, 1986, 75: 117-119. (Pubitemid 16162531)
2. Fagerholm U, Johansson M, Lennernas H. Comparison between permeability coefficients in rat and human jejunum [J]. Pharm Res, 1996, 13: 336-342. (Pubitemid 26344978)
3. Li SH, Wu LJ, Yin HY. Research on the chemical and pharmacological activity of zushima [J]. Chin J Chin Mater Med, 2000, 27: 401-403.
4. Gao Q, Shan JJ, Di LQ, et al. Therapeutic effects of daphnetin on adjuvant-induced arthritic rats [J]. J Ethnopharmacol, 2008, 120: 259-263.
5. Qu SY, Wu YJ, Wang YH, et al. Metabolism and pharmacokinetics of daphnetin [J]. Acta Pharm Sin, 1983, 18: 496-500.
6. Li KJ. Study on oral absorption mechanism of Indirubin [D]. Chengdu: Sichuan University, 2007.
7. Tan XB, Jia XB. Absorptive property of eleutheroside B in rat intestine [J]. Chin Tradit Pat Med, 2008, 30: 346-349.
8. Wu YN, Luan LB. In situ rats single pass perfusion intestinal absorption of the effective components in Radix Angelicae Pubescentis [J]. Acta Pharm Sin, 2008, 43: 102-107.
9. Li WL, Hu ZT, Ji YB, et al. Studies on absorption mechanism of logan in intestines of rats [J]. Chin J Chin Mater Med, 2008, 33: 1052-1055.
10. You J, Li QB, Yu YW, et al. Absorption of zedoary oil in rat intestine using in situ single pass perfusion model [J]. Acta Pharm Sin, 2004, 39: 849-853.
11. Qian GY, Shan JJ, Di LQ, et al. In situ rat's intestinal absorption kinetics of daphnetin [J]. J Nanjing Univ Tradit Chin Med, 2007, 23: 177-178.