Admission hypoglycaemia is associated with adverse outcome in community-acquired pneumonia

European Respiratory Journal

Volumn 34, Issue 4, 2009, Pages 932-939

  Singanayagam, A ^a   Chalmers, J D ^a   Hill, A T ^a  

^a ROYAL INFIRMARY OF EDINBURGH   (United Kingdom)

Author keywords

Community acquired pneumonia; Hypoglycaemia; Outcome

Indexed keywords

GLUCOSE; INOTROPIC AGENT; STATIN;

ADULT; ADVERSE OUTCOME; AGED; ARTICLE; ARTIFICIAL VENTILATION; COMMUNITY ACQUIRED PNEUMONIA; DIABETES MELLITUS; DISEASE ASSOCIATION; FEMALE; GLUCOSE BLOOD LEVEL; HOSPITAL ADMISSION; HUMAN; HYPOGLYCEMIA; MAJOR CLINICAL STUDY; MALE; MORTALITY; OBSERVATIONAL STUDY; PNEUMONIA SEVERITY INDEX; PRIORITY JOURNAL; PROSPECTIVE STUDY; UNITED KINGDOM;

AGED; BLOOD GLUCOSE; COMMUNITY-ACQUIRED INFECTIONS; DIABETES MELLITUS; FEMALE; HUMANS; HYPOGLYCEMIA; KAPLAN-MEIERS ESTIMATE; LOGISTIC MODELS; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; OUTCOME ASSESSMENT (HEALTH CARE); PNEUMONIA; PREDICTIVE VALUE OF TESTS; PROSPECTIVE STUDIES; RESPIRATION, ARTIFICIAL; RISK FACTORS; SEPSIS; SEVERITY OF ILLNESS INDEX;

EID: 70349644713     PISSN: 09031936     EISSN: 13993003     Source Type: Journal    
DOI: 10.1183/09031936.00197008     Document Type: Article

References (23)

1. Alamgir S, Volkova NB, Peterson MW. Prognostic value of low blood glucose at the presentation of E. Coli bacteraemia. Am J Med 2006; 119: 952-957. (Pubitemid 44634309)
2. McGeough EC, Walker JD. Hypoglycaemia with septicaemia: 2 case reports and a review of the literature. SMJ 2006; 51: 57.
3. Miller SI, Wallace RJ, Musher DM, et al. Hypoglycaemia as a manifestation of sepsis. Am J Med 1980; 68: 649-659.
4. Fine MJ, Auble TE, Yealy DM, et al. A prediction rule to identify low risk patients with community-acquired pneumonia. N Engl J Med 1997; 336: 243-250. (Pubitemid 27044625)
5. McCallister FA, Majumdar SR, Blitz S, et al. The relation between hyperglycaemia and outcomes in 2,471 patients admitted to hospital with community-acquired pneumonia. Diabetes Care 2005; 28: 810-815. (Pubitemid 40434478)
6. Baker EH, Wood DM, Brennan AL, et al. Hyperglycaemia and pulmonary infection. Proc Nutr Soc 2006; 65: 227-235.
7. British Thoracic Society Pneumonia Guidelines Committee. BTS Guidelines for the Management of Community Acquired Pneumonia in Adults - 2004 Update. Date last updated: April 30, 2004. www.brit-thoracic.org.uk/Portals/0/ clinical%20Information/Pneumonia/Guidelines/MACAPrevisedApr04.pdf.
8. Dellinger RP, Levy MM, Carlet JM, et al. Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock: 2008. Crit Care Med 2008; 36: 296-327.
9. Lim WS, van der Eerden MM, Laing R, et al. Defining community acquired pneumonia severity on presentation to hospital: an international derivation and validation study. Thorax 2003; 58: 377-382. (Pubitemid 36560938)
10. American College of Chest Physicians/Society of Critical Care Medicine Consensus Conference: definitions for sepsis and organ failure and guidelines for use of innovative therapies in sepsis. Crit Care Med 1992; 20: 864-874.
11. Chalmers JD, Singanayagam A, Murray MP, et al. Prior statin use is associated with improved outcomes in community-acquired pneumonia. Am J Med 2008; 121: 1002-1007.
12. Rattarasarn C. Hypoglycaemia and sepsis and risk factors and clinical characteristics. J Med Assoc Thai 1997; 80: 649-669. (Pubitemid 128519915)
13. Hinshaw LB, Payton MD, Archer LT, et al. Prevention of death in endotoxin shock by glucose administration. Surg Gynecol Obstet 1974; 139: 851-859.
14. Berk JL, Hagen JF, Beyer WH, et al. Hypoglycaemia of shock. Ann Surg 1970; 171: 400-408.
15. Shibayama Y. Role of endotoxin on hypoglycaemia in acute hepatic failure: relationship between hypoglycaemia and hepatic injury following endotoxaemia in diabetic and nondiabetic rats. Pathol Res Pract 1989; 184: 489-493. (Pubitemid 19160886)
16. Filkin JP, Cornell RP. Depression of hepatic gluconeogenesis and the hypoglycaemia of endotoxic shock. Am J Physiol 1974; 227: 778-781.
17. 2. Circ Shock 1981; 8: 601-611.
18. Romijn JA, Sauwewein HP. Hypoglycaemia induced by septic shock. Neth J Med 1988; 33: 68-73.
19. Manglik S, Flores E, Lubarsky L, et al. Glucocorticoid insufficiency in patients who present to the hospital with severe sepsis: a prospective clinical trial. Crit Care Med 2003; 31: 1668-1675. (Pubitemid 36714219)
20. Marik PE, Zaloga GP. Adrenal insufficiency during septic shock. Crit Care Med 2003; 31: 141-145.
21. Marik PE, Pastores SM, Annane D, et al. Recommendations for the diagnosis and management of corticosteroid insufficiency in critically ill adult patients: consensus statements from an international task force by the American College of Critical Care Medicine. Crit Care Med 2008; 36: 1987-1989.
22. Annane D. Adrenal insufficiency in sepsis. Curr Pharm Des 2008; 14: 1882-1886.
23. Annane D, Sebille V, Troche G, et al. A 3-level prognostic classification in septic shock based on cortisol levels and cortisol response to corticotropin. JAMA 2000; 283: 1038-1045. (Pubitemid 30112218)