Effect of Leucine and Lysine substitution on the antimicrobial activity and evaluation of the mechanism of the HPA3NT3 analog peptide

Journal of Peptide Science

Volumn 15, Issue 9, 2009, Pages 589-594

  Gopal, Ramamourthy ^a   Park, Seong Cheol ^a   Ha, Kyeoung Ju ^b   Cho, Seung Joo ^c   Kim, Si Wouk ^a   Song, Peter I ^d   Nah, Jae Woon ^e   Park, Yoonkyung ^a   Hahm, Kyung Soo ^a,c  

^a Chosun University   (South Korea)

^b Daegu Haany University   (South Korea)

^c Chosun University College of Medicine   (South Korea)

^d UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

^e Sunchon National University   (South Korea)

Author keywords

Antimicrobial activity; Hemolysis; HPA3NT3 analog peptide; Leakage of calcein; Molecular dynamics

Indexed keywords

ASPARAGINE; EGG YOLK L 2 PHOSPHATIDYLCHOLINE; LEUCINE; LYSINE; PHENYLALANYLLYSYLARGINYLLEUCYLLYSYLLYSYLLEUCYLPHENYLALANYLLYSYLLYSYLISOLEUCYLTRYPTOPHANYLASPARAGINYLLYSINE; PHENYLALANYLLYSYLLYSYLLEUCYLLYSYLLYSYLLEUCYLPHENYLALANYLLYSYLLYSYLISOLEUCYLLEUCYLLYSYLLEUCYLLYSINAMIDE; PHOSPHATIDYLCHOLINE; POLYPEPTIDE ANTIBIOTIC AGENT; TRIFLUOROETHANOL; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ANTIBACTERIAL ACTIVITY; ANTIFUNGAL ACTIVITY; BACILLUS SUBTILIS; CANDIDA ALBICANS; CIRCULAR DICHROISM; CONCENTRATION RESPONSE; CONFERENCE PAPER; CONTROLLED STUDY; DRUG BINDING; DRUG DESIGN; DRUG STRUCTURE; ESCHERICHIA COLI; FUNGUS; HUMAN; HUMAN CELL; LISTERIA MONOCYTOGENES; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PRIORITY JOURNAL; PSEUDOMONAS AERUGINOSA; SALMONELLA TYPHIMURIUM; STAPHYLOCOCCUS AUREUS; TRICHOSPORON BEIGELII;

AMINO ACID SUBSTITUTION; ANTIMICROBIAL CATIONIC PEPTIDES; CANDIDA ALBICANS; CIRCULAR DICHROISM; COMPUTER SIMULATION; FLUORESCEINS; GRAM-NEGATIVE BACTERIA; GRAM-POSITIVE BACTERIA; HEMOLYSIS; HUMANS; LEUCINE; LIPOSOMES; LYSINE; MICROBIAL SENSITIVITY TESTS; MODELS, MOLECULAR; STRUCTURE-ACTIVITY RELATIONSHIP; TRICHOSPORON;

BACTERIA (MICROORGANISMS); NEGIBACTERIA; POSIBACTERIA;

EID: 70349639934     PISSN: 10752617     EISSN: 10991387     Source Type: Journal    
DOI: 10.1002/psc.1155     Document Type: Conference Paper

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