Impact of multiaccess infusion devices on in vitro drug delivery during multi-infusion therapy

Anesthesia and Analgesia

Volumn 109, Issue 4, 2009, Pages 1147-1155

  Décaudin, Bertrand ^a,b,d   Dewulf, Sophie ^c   Lannoy, Damien ^a   Simon, Nicolas ^a   Secq, Alexandre ^c   Barthélémy, Christine ^a   Debaene, Bertrand ^d   Odou, Pascal ^a,b  

^a UNIV LILLE   (France)

^b LILLE UNIVERSITY HOSPITAL   (France)

^c Dunkerque General Hospital   (France)

^d POITIERS UNIVERSITY HOSPITAL   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ISOSORBIDE DINITRATE; MIDAZOLAM; NORADRENALIN;

ARTICLE; BOLUS INJECTION; CLINICAL ASSESSMENT; CONTROLLED STUDY; DEAD SPACE VOLUME; DRUG BLOOD LEVEL; DRUG DELIVERY SYSTEM; DRUG INJECTION VOLUME; FLOW KINETICS; FLOW RATE; HUMAN; IN VITRO STUDY; INFUSION; INFUSION SYSTEM; PRIORITY JOURNAL; STEADY STATE; SYRINGE; ULTRAVIOLET SPECTROPHOTOMETRY; VOLUMETRY; DRUG COMBINATION; EQUIPMENT DESIGN; INFUSION PUMP; INSTRUMENTATION; MATERIALS TESTING; REGRESSION ANALYSIS; TIME;

DRUG DELIVERY SYSTEMS; DRUG THERAPY, COMBINATION; EQUIPMENT DESIGN; HUMANS; INFUSION PUMPS; INFUSIONS, PARENTERAL; ISOSORBIDE DINITRATE; LEAST-SQUARES ANALYSIS; MATERIALS TESTING; MIDAZOLAM; NOREPINEPHRINE; SPECTROPHOTOMETRY, ULTRAVIOLET; SYRINGES; TIME FACTORS;

EID: 70349581202     PISSN: 00032999     EISSN: None     Source Type: Journal    
DOI: 10.1213/ane.0b013e3181ae06e3     Document Type: Article

References (14)

1. Lauven PM, Stoeckel H, Schwilden H. A microprocessor controlled infusion scheme for midazolam to achieve constant plasma levels. Anaesthesist 1982;31:15-20 (Pubitemid 12167142)
2. White PF. Clinical uses of intravenous anesthetic and analgesic infusions. Anesth Analg 1989;68:161-171 (Pubitemid 19056360)
3. Shafer SL, Gregg KM. Algorithms to rapidly achieve and maintain stable drug concentrations at the site of drug effect with a computer-controlled infusion pump. J Pharmacokinet Biopharm 1992;20:147-169
4. Bailey JM. A technique for approximately maintaining constant plasma levels of intravenous drugs. Anesthesiology 1993;78: 116-123
5. Miller DR. Intravenous infusion anaesthesia and delivery devices. Can J Anaesth 1994;41:639-651
6. Gepts E. Pharmacokinetic concepts for TCI anaesthesia. Anaesthesia 1998;53:4-12
7. Russell D. Intravenous anaesthesia: manual infusion schemes versus TCI systems. Anaesthesia 1998;53:42-45 (Pubitemid 28258625)
8. Van Poucke GE, Bravo LJ, Shafer SL. Target controlled infusions: targeting the effect site while limiting peak plasma concentration. IEEE Trans Biomed Eng 2004;51:1869-1875
9. Crass RE, Vance JR. In vivo accuracy of gravity-flow i.v. infusion systems. Am J Hosp Pharm 1985;42:328-331
10. Ziser M, Feezor M, Skolaut MW. Regulating intravenous fluid flow: controller versus clamps. Am J Hosp Pharm 1979;36: 1090-1094
11. Lovich MA, Doles J, Peterfreund RA. The impact of carrier flow rate and infusion set dead-volume on the dynamics of intravenous drug delivery. Anesth Analg 2005;100:1048-1055 (Pubitemid 40404209)
12. Lovich MA, Kinnealley ME, Sims NM, Peterfreund RA. The delivery of drugs to patients by continuous intravenous infusion: modelling predicts potential dose fluctuations depending on flow rates and infusion system dead volume. Anesth Analg 2006;102:1147-1153
13. Flack FC, Whyte TD. Variations of drop size in disposable administration sets used for intravenous infusion. J Clin Pathol 1975;28:510-512
14. Hutton P, Thornberry EA. Factors affecting delivery of drug through extension tubing. Br J Anaesth 1986;58:1141-1148 (Pubitemid 16031591)