Renal glucose excretion and tubular reabsorption rate related to blood glucose in subjects with type 2 diabetes with a critical reappraisal of the renal glucose threshold model

Hormone and Metabolic Research

Volumn 41, Issue 8, 2009, Pages 600-604

  Wolf, S ^a   Rave, K ^a   Heinemann, L ^a   Roggen, K ^a  

^a Profil Institut fur Stoffwechselforschung GmbH   (Germany)

Author keywords

Hyperglycaemic glucoseclamp; Renal threshold for glucose excretion; Splay; Tubular transport maximum for glucose; Type 2 diabetes mellitus; Urinary glucose

Indexed keywords

GLUCOSE;

ADULT; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; GLUCOSE ABSORPTION; GLUCOSE BLOOD LEVEL; GLUCOSE CLAMP TECHNIQUE; GLUCOSE TRANSPORT; GLUCOSE URINE LEVEL; HUMAN; KIDNEY FUNCTION; KIDNEY TUBULE ABSORPTION; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; PRIORITY JOURNAL; STEADY STATE; URINALYSIS; URINARY EXCRETION; BIOLOGICAL MODEL; KIDNEY; KIDNEY TUBULE; METABOLISM; MIDDLE AGED; PATHOPHYSIOLOGY;

ADULT; BLOOD GLUCOSE; DIABETES MELLITUS, TYPE 2; FEMALE; GLUCOSE; GLUCOSE CLAMP TECHNIQUE; HUMANS; KIDNEY; KIDNEY TUBULES; MALE; MIDDLE AGED; MODELS, BIOLOGICAL;

EID: 70349567392     PISSN: 00185043     EISSN: 14394286     Source Type: Journal    
DOI: 10.1055/s-0029-1220723     Document Type: Article

References (40)

1. Deetjen P, Drexel H, Aczel S. Renal handling of D -Glucose and Other Sugars. In: Massry SG, Glassock RJ, ed. Massry and Glassock's Textbook of Nephrology Philadelphia: Lippincott Williams & Wilkins 2001 87-90
2. Deetjen P, Baeyer Hv, Drexel H. Renal glucose transport. In: Seldin DW, Giebisch G, ed. The kidney: physiology and pathophysiology New York: Raven Press 1992 2873- 2888
3. Davison JM, Cheyne GA. Renal reabsorption of glucose. Lancet 1972 1 787-788
4. Davison JM, Cheyne GA. History of the measurement of glucose in urine: a cautionary tale. Med Hist 1974 18 194-197
5. Shannon JA, Farber S, Troast L. The measurement of glucose Tm in the normal dog. Am J Physiol 1941 133 752-761
6. Brodehl J, Franken A, Gellissen K. Maximal tubular reabsorption of glucose in infants and children. Acta Paediatr Scand 1972 61 413-420
7. Rohde R, Deetjen P. Glucose reabsorption in the rat kidney. Micro-puncture analysis of tubular glucose concentration during free flow. Pflugers Arch 1968 302 219-232
8. Hierholzer K, Fromm M. Funktionen der Nieren. In: Schmidt RF, Thews G, ed. Physiologie des Menschen Berlin: Springer 1997 737-777
9. Golenhofen K. Physiologie 1997 386-392
10. Berger M, Sawicki PT. Coma diabeticum. In: Berger M, ed. Diabetes mellitus München: Urban & Fischer 2000 387-393
11. Bojunga J, Badenhoop K, Althoff PH, Usadel KH. Akute Stoffwechselentgleisungen. In: Mehnert H, Standl E, Usadel KH, Häring HU, ed. Diabetologie in Klinik und Praxis Stuttgart: Georg Thieme 2003 376-399
12. Grüneklee D. Diagnostik und Therapiekontrolle des Diabetes mellitus. In: Rosak C, ed. Angewandte Diabetologie Bremen: UNI-MED 2005 40-65
13. Krautzig S. Niere. In: Renz-Polster H, Braun J, ed. Basislehrbuch Innere Medizin München: Urban & Fischer 2001 840-913
14. Lazarus A. 3. ber alimentäre Glykosurie. Z rztl Fortbild (Jena) 1904 1 517-520
15. Benedict SR, Osterberg E. A method for the determination of sugar in normal urine. J Biol Chem 1918 34 195-201
16. Brodehl J, Oemar BS, Hoyer PF. Renal glucosuria. Pediatr Nephrol 1987 1 502-508
17. Fine J. Glucose content of normal urine. Br Med J 1965 1 1209-1214
18. Folin O. A qualitative (reduction) test for sugar in normal human urine. J Biol Chem 1915 22 327-329
19. Gupta RC, Goyal A, Ghosh R, Punjabi M, Singh PP. Normal range for glucose in urine: age-related changes. Clin Chem 1982 28 2335
20. Hanusch AW, Kaiser G. A contribution to urinary glucose excretion of metabolically healthy persons. Dtsch Gesundheitsw 1968 23 1888-1892
21. Heimsoth VH, Graffe-Achelis C, Banauch D, Vollmar J. Referenzwerte für die Glukosekonzentration im Urin von Erwachsenen. Med Lab (Stuttg) 1978 31 236-240
22. Heinemann L, Sawicki PT, Niederau CM, Starke AAR. Klinische Chemie. In: Berger M, ed. Diabetes Mellitus München: Urban & Fischer 2000 44-65
23. Jain S. Reference interval for urinary glucose in elderly subjects. Clin Chem 1986 32 711-712
24. Jain S. Reference interval for urinary glucose: effect of age. Clin Chem 1986 32 1426
25. Kruse-Jarres JD, Reinauer H, Witt I. Kohlenhydratstoffwechsel. In: Greiling H, Gressner AM, ed. Lehrbuch der klinischen Chemie und Pathobiochemie Stuttgart: Schattauer 1995 248-299
26. Renschler HE, Weicker H, von Baeyer H. The upper limit of glucose concentration in the urine of healthy subjects]. Dtsch Med Wochenschr 1965 90 2349-2353
27. Sindoni A. Blood sugar versus urine sugar. J Am Med Assoc 1939 112 2503-2504
28. Thomas L. Glucose im Harn und anderen Körperflüssigkeiten. In: Thomas L, ed. Labor und Diagnose Frankfurt/Main: TH-Books 1998 141-142
29. Butterfield WJ, Keen H, Whichelow MJ. Renal glucose threshold variations with age. Br Med J 1967 4 505-507
30. Walford S, Page MM, Allison SP. The influence of renal threshold on the interpretation of urine tests for glucose in diabetic patients. Diabetes Care 1980 3 672-674
31. Winter KA. Relationships between blood and urinary sugar and their clinical significance. 1. Methodical studies and results. Z Gesamte Inn Med 1973 28 189-194
32. Winter KA. Relationships between blood and urinary sugar and their clinical significance. 2. Clinical significance of marginal blood sugar value determinations. Z Gesamte Inn Med 1973 28 217-222
33. Menzel R, Kaisaki PJ, Rjasanowski I, Heinke P, Kerner W, Menzel S. A low renal threshold for glucose in diabetic patients with a mutation in the hepatocyte nuclear factor-1 (HNF-1) gene. Diabet Med 1998 15 816-820
34. Ruhnau B, Faber OK, Borch-Johnsen K, Thorsteinsson B. Renal threshold for glucose in non-insulin-dependent diabetic patients. Diabetes Res Clin Pract 1997 36 27-33
35. Mohnike G, Lisewski G, Israel HJ. The threshold point for glucose in diabetes mellitus and renal diabetes. Z Gesamte Inn Med 1961 16 1073-1077
36. Report of the Expert Committee on the Diagnosis and Classification of Diabetes Mellitus. Diabetes Care 1997 20 1183-1197
37. Rule AD, Larson TS, Bergstralh EJ, Slezak JM, Jacobsen SJ, Cosio FG. Using serum creatinine to estimate glomerular filtration rate: accuracy in good health and in chronic kidney disease. Ann Intern Med 2004 141 929-937
38. Rave K, Nosek L, Posner J, Heise T, Roggen K, van Hoogdalem E-J. Renal glucose excretion as a function of blood glucose concentration in subjects with type 2 diabetes results of a hyperglycaemic glucose clamp study. Nephrol Dial Transplant 2006 21 2166-2171
39. Johansen K, Svendsen PA, Lorup B. Variations in renal threshold for glucose in Type 1 (insulin-dependent) diabetes mellitus. Diabetologia 1984 26 180-182
40. Erkelens DW, Dullaart R, Peuker N. Tubular reabsorption of glucose in quantifying the relation between blood glucose and urinary glucose excretion in diabetic patients. Neth J Med 1983 26 1-9