Nuclear receptors: The controlling force in drug metabolism of the liver?

Xenobiotica

Volumn 39, Issue 8, 2009, Pages 597-605

  Plant, N ^a   Aouabdi, S ^a  

^a UNIVERSITY OF SURREY   (United Kingdom)

Author keywords

Constitutive androstane receptor (CAR); Cross talk; Peroxisome proliferatoractivated receptor (PPAR); Pregnane X receptor (PXR); Vitamin D receptor (VDR)

Indexed keywords

1,4 BIS(3,5 DICHLORO 2 PYRIDYLOXY)BENZENE; BILE ACID; BILE SALT; BILIRUBIN; CELL NUCLEUS RECEPTOR; CHOLESTANETRIOL 26 MONOOXYGENASE; CONSTITUTIVE ANDROSTANE RECEPTOR; CYTOCHROME P450; CYTOCHROME P450 2B; CYTOCHROME P450 2B6; CYTOCHROME P450 3A; CYTOCHROME P450 3A4; CYTOCHROME P450 4A; DEXAMETHASONE; FARNESOID X RECEPTOR; GLUCOCORTICOID; GLUCOCORTICOID RECEPTOR; HEPATOCYTE NUCLEAR FACTOR 1ALPHA; HEPATOCYTE NUCLEAR FACTOR 3ALPHA; HEPATOCYTE NUCLEAR FACTOR 3BETA; HEPATOCYTE NUCLEAR FACTOR 3GAMMA; HEPATOCYTE NUCLEAR FACTOR 4ALPHA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR DELTA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PHENOBARBITAL; PREGNANE X RECEPTOR; RIFAMPICIN; UNINDEXED DRUG; XENOBIOTIC AGENT; CELL RECEPTOR;

AMINO TERMINAL SEQUENCE; BIOSYNTHESIS; CARBOXY TERMINAL SEQUENCE; CHOLESTEROL METABOLISM; DOWN REGULATION; DRUG BINDING SITE; DRUG CONJUGATION; DRUG METABOLISM; DRUG RECEPTOR BINDING; DRUG TRANSPORT; ENZYME INDUCTION; ENZYME REGULATION; FATTY ACID METABOLISM; GENE ACTIVATION; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENE TARGETING; GLUCOSE METABOLISM; HOMEOSTASIS; HUMAN; LIVER METABOLISM; MOLECULAR INTERACTION; MOLECULAR MECHANICS; MOLECULAR SENSOR; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN STRUCTURE; RECEPTOR UPREGULATION; REVIEW; RISK ASSESSMENT; SIGNAL TRANSDUCTION; TRANSCRIPTION INITIATION; TRANSCRIPTION REGULATION; ANIMAL; DRUG EFFECT; DRUG INTERACTION; DRUG SCREENING; LIVER; METABOLISM; OXIDATION REDUCTION REACTION;

ANIMALS; DRUG EVALUATION, PRECLINICAL; DRUG INTERACTIONS; ENZYME INDUCTION; HOMEOSTASIS; HUMANS; LIVER; OXIDATION-REDUCTION; RECEPTORS, CYTOPLASMIC AND NUCLEAR; XENOBIOTICS;

EID: 70349562260     PISSN: 00498254     EISSN: 13665928     Source Type: Journal    
DOI: 10.1080/00498250903098218     Document Type: Review

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