Clinical Outcome of Dose-Escalated Image-Guided Radiotherapy for Spinal Metastases

International Journal of Radiation Oncology Biology Physics

Volumn 75, Issue 3, 2009, Pages 828-835

  Guckenberger, Matthias ^a   Goebel, Joachim ^a   Wilbert, Juergen ^a   Baier, Kurt ^a   Richter, Anne ^a   Sweeney, Reinhart A ^a   Bratengeier, Klaus ^a   Flentje, Michael ^a  

^a UNIVERSITY OF WÜRZBURG   (Germany)

Author keywords

Cone beam computed tomography; Image guided radiotherapy; IMRT; Intensity modulated radiotherapy; Oligometastatic; Spinal metastasis

Indexed keywords

CONE-BEAM COMPUTED TOMOGRAPHY; IMAGE-GUIDED RADIOTHERAPY; IMRT; INTENSITY-MODULATED RADIOTHERAPY; OLIGOMETASTATIC; SPINAL METASTASIS;

COMPUTERIZED TOMOGRAPHY; ONCOLOGY; PATIENT MONITORING; PHYSICAL THERAPY; RADIOTHERAPY; TOXICITY; TUMORS;

PATHOLOGY;

ACUTE TOXICITY; ADULT; AGED; ANALGESIA; ARTICLE; CANCER CONTROL; CANCER RADIOTHERAPY; CANCER RECURRENCE; CANCER SURVIVAL; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE COURSE; DOSIMETRY; DYSPHAGIA; EPIDURAL SPACE; ERYTHEMA; FOLLOW UP; HUMAN; HYPERPIGMENTATION; INTENSITY MODULATED RADIATION THERAPY; LIFE EXPECTANCY; MEDICAL ERROR; OVERALL SURVIVAL; PAIN; PATIENT SAFETY; PRESCRIPTION; PRIORITY JOURNAL; RADIATION DOSE FRACTIONATION; RADIATION INJURY; SCHOOL CHILD; SKIN EXFOLIATION; SKIN TOXICITY; SPINAL CORD DISEASE; SPINAL CORD METASTASIS; SPINAL CORD TUMOR; SURVIVAL RATE; SURVIVAL TIME; TREATMENT OUTCOME; TREATMENT PLANNING; VERTEBRAL CANAL;

ADULT; AGED; CHILD; CONE-BEAM COMPUTED TOMOGRAPHY; FEMALE; HUMANS; LIFE EXPECTANCY; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; RADIATION INJURIES; RADIOTHERAPY DOSAGE; RADIOTHERAPY PLANNING, COMPUTER-ASSISTED; RADIOTHERAPY, INTENSITY-MODULATED; RETROSPECTIVE STUDIES; SPINAL NEOPLASMS; SURVIVAL RATE; TREATMENT OUTCOME;

EID: 70349554703     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2008.11.017     Document Type: Article

References (31)

1. Wong D.A., Fornasier V.L., and MacNab I. Spinal metastases: The obvious, the occult, and the impostors. Spine 15 (1990) 1-4
2. Rades D., Stalpers L.J., Veninga T., et al. Evaluation of five radiation schedules and prognostic factors for metastatic spinal cord compression. J Clin Oncol 23 (2005) 3366-3375
3. Wu J.S., Wong R., Johnston M., et al. Meta-analysis of dose-fractionation radiotherapy trials for the palliation of painful bone metastases. Int J Radiat Oncol Biol Phys 55 (2003) 594-605
4. Sze W.M., Shelley M.D., Held I., et al. Palliation of metastatic bone pain: Single fraction versus multifraction radiotherapy-A systematic review of randomised trials. Clin Oncol (R Coll Radiol) 15 (2003) 345-352
5. Rades D., Veninga T., Stalpers L.J., et al. Prognostic factors predicting functional outcomes, recurrence-free survival, and overall survival after radiotherapy for metastatic spinal cord compression in breast cancer patients. Int J Radiat Oncol Biol Phys 64 (2006) 182-188
6. Katagiri H., Takahashi M., Wakai K., et al. Prognostic factors and a scoring system for patients with skeletal metastasis. J Bone Joint Surg Br 87 (2005) 698-703
7. Teshima T., Chatani M., Inoue T., et al. Prognostic factors for patients with osseous metastasis: a multi-institutional prospective study. Strahlenther Onkol 166 (1990) 387-391
8. Tokuhashi Y., Matsuzaki H., Toriyama S., et al. Scoring system for the preoperative evaluation of metastatic spine tumor prognosis. Spine 15 (1990) 1110-1113
9. Emami B., Lyman J., Brown A., et al. Tolerance of normal tissue to therapeutic irradiation. Int J Radiat Oncol Biol Phys 21 (1991) 109-122
10. Schultheiss T.E., Kun L.E., Ang K.K., et al. Radiation response of the central nervous system. Int J Radiat Oncol Biol Phys 31 (1995) 1093-1112
11. Sahgal A., Larson D.A., and Chang E.L. Stereotactic body radiosurgery for spinal metastases: A critical review. Int J Radiat Oncol Biol Phys 71 (2008) 652-665
12. Nevinny-Stickel M., Sweeney R.A., Bale R.J., et al. Reproducibility of patient positioning for fractionated extracranial stereotactic radiotherapy using a double-vacuum technique. Strahlenther Onkol 180 (2004) 117-122
13. Guckenberger M., Meyer J., Wilbert J., et al. Intra-fractional uncertainties in cone-beam CT based image-guided radiotherapy (IGRT) of pulmonary tumors. Radiother Oncol 83 (2007) 57-64
14. Ryu S., Rock J., Rosenblum M., et al. Patterns of failure after single-dose radiosurgery for spinal metastasis. J Neurosurg 101 Suppl. 3 (2004) 402-405
15. Gerszten P.C., Burton S.A., Ozhasoglu C., et al. Radiosurgery for spinal metastases: Clinical experience in 500 cases from a single institution. Spine 32 (2007) 193-199
16. Breen S.L., Craig T., Bayley A., et al. Spinal cord planning risk volumes for intensity-modulated radiation therapy of head-and-neck cancer. Int J Radiat Oncol Biol Phys 64 (2006) 321-325
17. Bratengeier K. 2-Step IMAT and 2-Step IMRT in three dimensions. Med Phys 32 (2005) 3849-3861
18. van Herk M. Errors and margins in radiotherapy. Semin Radiat Oncol 14 (2004) 52-64
19. Gibbs I.C., Kamnerdsupaphon P., Ryu M.R., et al. Image-guided robotic radiosurgery for spinal metastases. Radiother Oncol 82 (2007) 185-190
20. Rock J.P., Ryu S., Shukairy M.S., et al. Postoperative radiosurgery for malignant spinal tumors. Neurosurgery 58 (2006) 891-898
21. Sahgal A., Chou D., Ames C., et al. Proximity of spinous/paraspinous radiosurgery metastatic targets to the spinal cord versus risk of local failure. Int J Radiat Oncol Biol Phys 69 (2007) S243
22. Chang E.L., Shiu A.S., Mendel E., et al. Phase I/II study of stereotactic body radiotherapy for spinal metastasis and its pattern of failure. J Neurosurg Spine 7 (2007) 151-160
23. Kim B., Soisson E.T., Duma C., et al. Image-guided helical tomotherapy for treatment of spine tumors. Clin Neurol Neurosurg 110 (2008) 357-362
24. Wara W.M., Phillips T.L., Sheline G.E., et al. Radiation tolerance of the spinal cord. Cancer 35 (1975) 1558-1562
25. Macbeth F.R., Wheldon T.E., Girling D.J., et al., Medical Research Council Lung Cancer Working Party. Radiation myelopathy: Estimates of risk in 1048 patients in three randomized trials of palliative radiotherapy for non-small cell lung cancer. Clin Oncol (R Coll Radiol) 8 (1996) 176-181
26. Ryu S., Jin J.Y., Jin R., et al. Partial volume tolerance of the spinal cord and complications of single-dose radiosurgery. Cancer 109 (2007) 628-636
27. Guckenberger M., Meyer J., Wilbert J., et al. Precision of image-guided radiotherapy (IGRT) in six degrees of freedom and limitations in clinical practice. Strahlenther Onkol 183 (2007) 307-313
28. Meyer J., Wilbert J., Baier K., et al. Positioning accuracy of cone-beam computed tomography in combination with a HexaPOD robot treatment table. Int J Radiat Oncol Biol Phys 67 (2007) 1220-1228
29. Guckenberger M., Meyer J., Wilbert J., et al. Precision required for dose-escalated treatment of spinal metastases and implications for image-guided radiation therapy (IGRT). Radiother Oncol 84 (2007) 56-63
30. Guckenberger M., Meyer J., Vordermark D., et al. Magnitude and clinical relevance of translational and rotational patient setup errors: A cone-beam CT study. Int J Radiat Oncol Biol Phys 65 (2006) 934-942
31. Rades D., Dunst J., and Schild S.E. The first score predicting overall survival in patients with metastatic spinal cord compression. Cancer 112 (2008) 157-161