Relationship of serum bilirubin concentrations to kidney function and albuminuria in the united states adult population. findings from the national health and nutrition examination survey 2001-2006

Clinical Chemistry and Laboratory Medicine

Volumn 47, Issue 9, 2009, Pages 1055-1062

  Targher, Giovanni ^a   Bosworth, Cortney ^b   Kendrick, Jessica ^b   Smits, Gerard ^b   Lippi, Giuseppe ^c   Chonchol, Michel ^b  

^a UNIVERSITY OF VERONA   (Italy)

^b UNIVERSITY OF COLORADO   (United States)

^c UNIVERSITY HOSPITAL OF VERONA   (Italy)

Author keywords

Albuminuria; Bilirubin; Epidemiology; Estimated glomerular filtration rate; Liver dysfunction

Indexed keywords

ALBUMIN; ALCOHOL; BILIRUBIN; CREATININE;

ADULT; AGED; ALBUMINURIA; ALCOHOL CONSUMPTION; ARTICLE; BILIRUBIN BLOOD LEVEL; COHORT ANALYSIS; COMORBIDITY; CONTROLLED STUDY; CROSS-SECTIONAL STUDY; DATA ANALYSIS; DEMOGRAPHY; DIABETES MELLITUS; FEMALE; GLOMERULUS FILTRATION RATE; HEALTH SURVEY; HUMAN; KIDNEY FUNCTION; LABORATORY TEST; MALE; MATHEMATICAL PARAMETERS; NUTRITION; POPULATION; PRIORITY JOURNAL; PUBLIC HEALTH; SAMPLE; UNITED STATES; URINARY EXCRETION; VIRUS HEPATITIS;

ADULT; AGED; ALBUMINURIA; BILIRUBIN; COHORT STUDIES; DATA INTERPRETATION, STATISTICAL; DEMOGRAPHY; FEMALE; GLOMERULAR FILTRATION RATE; HUMANS; KIDNEY DISEASES; MALE; MIDDLE AGED; NUTRITION SURVEYS; POPULATION GROUPS; UNITED STATES;

EID: 70349501469     PISSN: 14346621     EISSN: 14374331     Source Type: Journal    
DOI: 10.1515/CCLM.2009.244     Document Type: Article

References (38)

1. Coresh J, Selvin E, Stevens LA, Manzi J, Kusek JW, Eggers P, et al. Prevalence of chronic kidney disease in the United States. J Am Med Assoc 2007;298:2038-2047 (Pubitemid 350074801)
2. Hsu CY, Go AS, McCulloch CE, Darbinian J, Iribarren C. Exploring secular trends in the likelihood of receiving treatment for end-stage renal disease. Clin J Am Soc Nephrol 2007;2:81-88
3. Muntner P, He J, Hamm L, Loria C, Whelton PK. Renal insufficiency and subsequent death resulting from cardiovascular disease in the United States. J Am Soc Nephrol 2002;13:745-753
4. Go AS, Chertow GM, Fan D, McCulloch CE, Hsu CY. Chronic kidney disease and the risks of death, cardiovascular events, and hospitalization. N Engl J Med 2004; 351:1296-1305
5. van Domburg RT, Hoeks SE, Welten GM, Chonchol M, Elhendy A, Poldermans D. Renal insufficiency and mortality in patients with known or suspected coronary artery disease. J Am Soc Nephrol 2008;19:158-163
6. Rifkin DE, Shlipak MG, Katz R, Fried LF, Siscovick D, Chonchol M, et al. Rapid kidney function decline and mortality risk in older adults. Arch Intern Med 2008;168:2212-2218
7. Schwertner HA, Jackson WG, Tolan G. Association of low serum concentration of bilirubin with increased risk of coronary artery disease. Clin Chem 1994;40:18-23.
8. Vítek L, Jirsa M, Brodanova M, Kalab M, Marecek Z, Danzig V, et al. Gilbert syndrome and ischemic heart disease: A protective effect of elevated bilirubin levels. Atherosclerosis 2002;160:449-456
9. Djousse L, Levy D, Cupples LA, Evans JC, D'Agostino RB, Ellison RC. Total serum bilirubin and risk of cardiovascular disease in the Framingham offspring study. Am J Cardiol 2001;87:1196-1200
10. Perlstein TS, Pande RL, Beckman JA, Creager MA. Serum total bilirubin level and prevalent lower-extremity peripheral arterial disease: National Health and Nutrition Examination Survey (NHANES) 1999 to 2004. Arterioscler Thromb Vasc Biol 2008;28:166-172
11. Breimer LH, Wannamethee G, Ebrahim S, Shaper AG. Serum bilirubin and risk of ischemic heart disease in middle-aged British men. Clin Chem 1995;41:1504-1508
12. Rosenthal P, Pincus M, Fink D. Sex- and age-related differences in bilirubin concentrations in serum. Clin Chem 1984;30:1380-1382
13. Fukui M, Tanaka M, Shiraishi E, Harusato I, Hosoda H, Asano M, et al. Relationship between serum bilirubin and albuminuria in patients with type 2 diabetes. Kidney Int 2008;74:1197-1201
14. Targher G, Zoppini G, Guidi GC, Lippi G. Relationship between serum bilirubin and kidney function in nondiabetic and diabetic individuals. Kidney Int 2009;75:863.
15. US Department of Health and Human Services, Centers for Disease Control and Prevention. National Health and Nutrition Examination Survey. http://www.cdc.gov/nchs/ nhanes.htm.
16. National Center for Health Statistics. National Health and Nutrition Examination Survey (NHANES) Analytic Guidelines. http://www.cdc.gov/nchs/about/ major/nhanes/nhanes2003-2004/analytical-guidelines.htm.
17. National Center for Health Statistics, Centers for Disease Control. Survey operations manuals, brochures, and consent documents: 1999-current NHANES. http://www.cdc.gov/nchs/about/major/nhanes/currentnhanes.htm.
18. Stevens LA, Coresh J, Greene T, Levey AS. Assessing kidney function-measured and estimated glomerular filtration rate. N Engl J Med 2006;354:2473-2483
19. National Health and Nutrition Examination Survey 2005-2006. Documentation, codebook, and frequencies, 2008. Available at http://www.cdc.gov/nchs/data/nhanes/nhanes-05-06/biopro-d.pdf.
20. Selvin E, Manzi J, Stevens LA, Van Lente F, Lacher DA, Levey AS, et al. Calibration of serum creatinine in the National Health and Nutrition Examination Surveys (NHANES) 1988-1994, 1999, 2004. Am J Kidney Dis 2007; 50:918-926
21. Bonora E, Targher G, Alberiche M, Bonadonna RC, Saggiani F, Zenere MB, et al. Homeostasis model assessment closely mirrors the glucose clamp technique in the assessment of insulin sensitivity. Studies in subjects with various degrees of glucose tolerance and insulin sensitivity. Diabetes Care 2000;23:57-63.
22. Berk PD, Jones EA, Howe RB, Berlin NI. Disorders of bilirubin metabolism. In: Bondy IK, Rosenberg LE, editors. Metabolic control and disease, 8th ed. Philadelphia: Saunders, 1980.
23. Angulo P. Nonalcoholic fatty liver disease. N Engl J Med 2002;346:1221-1231
24. Clark JM, Brancati FL, Diehl AM. The prevalence and etiology of elevated aminotransferase levels in the United States. Am J Gastroenterol 2003;98:960-967
25. de Alwis NM, Day CP. Non-alcoholic fatty liver disease: The mist gradually clears. J Hepatol 2008;48(Suppl 1): S104-12.
26. Targher G, Marra F, Marchesini G. Increased risk of cardiovascular disease in non-alcoholic fatty liver disease: Causal effect or epiphenomenon? Diabetologia 2008;51: 1947-1953
27. Abiru S, Migita K, Maeda Y, Daikoku M, Ito M, Ohata K, et al. Serum cytokine and soluble cytokine receptor levels in patients with non-alcoholic steatohepatitis. Liver Int 2006;26:39-45.
28. Hui JM, Hodge A, Farrell GC, Kench JG, Kriketos A, George J. Beyond insulin resistance in NASH: TNF-alpha or adiponectin? Hepatology 2004;40:46-54.
29. Targher G, Bertolini L, Rodella S, Lippi G, Franchini M, Zoppini G, et al. NASH predicts plasma inflammatory biomarkers independently of visceral fat in men. Obesity (Silver Spring) 2008;16:1394-1399
30. Chalasani N, Deeg MA, Crabb DW. Systemic levels of lipid peroxidation and its metabolic and dietary correlates in patients with non-alcoholic steatohepatitis. Am J Gastroenterol 2004;99:1497-1502
31. Haukeland JW, Damås JK, Konopski Z, Løberg EM, Haaland T, Goverud I, et al. Systemic inflammation in nonalcoholic fatty liver disease is characterized by elevated levels of CCL2. J Hepatol 2006;44:1167-1174
32. Modlinger PS, Wilcox CS, Aslam S. Nitric oxide, oxidative stress, and progression of chronic renal failure. Semin Nephrol 2004;24:354-365
33. Kaysen GA, Eiserich JP. The role of oxidative stressaltered lipoprotein structure and function and microinflammation on cardiovascular risk in patients with minor renal dysfunction. J Am Soc Nephrol 2004;15:538-548
34. Stenvinkel P, Ketteler M, Johnson RJ, Lindholm B, Pecoits-Filho R, Riella M, et al. IL-10, IL-6, and TNF-alpha: Central factors in the altered cytokine network of uremia - the good, the bad, and the ugly. Kidney Int 2005;6: 1216-1233
35. Baylis C. Arginine, arginine analogs and nitric oxide production in chronic kidney disease. Nat Clin Pract Nephrol 2006;2:209-220
36. Cheng AY, Kong AP, Wong VW, So WY, Chan HL, Ho CS, et al. Chronic hepatitis B viral infection independently predicts renal outcome in type 2 diabetic patients. Diabetologia 2006;49:1777-1784
37. Chang Y, Ryu S, Sung E, Woo HY, Oh E, Cha K, et al. Nonalcoholic fatty liver disease predicts chronic kidney disease in non-hypertensive and non-diabetic Korean men. Metabolism 2008;57:569-576
38. Targher G, Chonchol M, Bertolini L, Rodella S, Zenari L, Lippi G, et al. Increased risk of CKD among type 2 diabetics with nonalcoholic fatty liver disease. J Am Soc Nephrol 2008;19:1564-1570