메뉴 건너뛰기




Volumn 11, Issue 8, 2009, Pages 645-654

Diverse genomic integration of a lentiviral vector developed for the treatment of Wiskott-Aldrich syndrome

Author keywords

Genomic integration; Hematopoiesis; Lentiviral vector; Mouse; Wiskott Aldrich

Indexed keywords

GENOMIC DNA; LENTIVIRUS VECTOR;

EID: 70349501369     PISSN: 1099498X     EISSN: 15212254     Source Type: Journal    
DOI: 10.1002/jgm.1346     Document Type: Article
Times cited : (17)

References (17)
  • 1
    • 20144389599 scopus 로고    scopus 로고
    • A lentiviral vector encoding the human Wiskott-Aldrich syndrome protein corrects immune and cytoskeletal defects in WASP knockout mice
    • Charrier S, Stockholm D, Seye K, et al. A lentiviral vector encoding the human Wiskott-Aldrich syndrome protein corrects immune and cytoskeletal defects in WASP knockout mice. Gene Ther 2005; 12: 597-606.
    • (2005) Gene Ther , vol.12 , pp. 597-606
    • Charrier, S.1    Stockholm, D.2    Seye, K.3
  • 2
    • 33645458063 scopus 로고    scopus 로고
    • Efficacy of gene therapy for Wiskott-Aldrich syndrome using a WAS promoter/ cDNA-containing lentiviral vector and nonlethal irradiation
    • Dupre L, Marangoni F, Scaramuzza S, et al. Efficacy of gene therapy for Wiskott-Aldrich syndrome using a WAS promoter/ cDNA-containing lentiviral vector and nonlethal irradiation. Hum Gene Ther 2006; 17: 303-313.
    • (2006) Hum Gene Ther , vol.17 , pp. 303-313
    • Dupre, L.1    Marangoni, F.2    Scaramuzza, S.3
  • 3
    • 33847178027 scopus 로고    scopus 로고
    • Lentiviral vectors targeting WASp expression to hematopoietic cells, efficiently transduce and correct cells from WAS patients
    • Charrier S, Dupre L, Scaramuzza S, et al. Lentiviral vectors targeting WASp expression to hematopoietic cells, efficiently transduce and correct cells from WAS patients. Gene Ther 2007; 14: 415-428.
    • (2007) Gene Ther , vol.14 , pp. 415-428
    • Charrier, S.1    Dupre, L.2    Scaramuzza, S.3
  • 4
    • 67349217158 scopus 로고    scopus 로고
    • Evidence for long-term efficacy and safety of gene therapy for Wiskott-Aldrich syndrome in preclinical models
    • Mar 3 [Epub ahead of print
    • Marangoni F, Bosticardo M, Charrier S, et al. Evidence for long-term efficacy and safety of gene therapy for Wiskott-Aldrich syndrome in preclinical models. Mol Ther 2009; Mar 3 [Epub ahead of print].
    • (2009) Mol Ther
    • Marangoni, F.1    Bosticardo, M.2    Charrier, S.3
  • 5
    • 28144462457 scopus 로고    scopus 로고
    • Genome-wide analysis of retroviral DNA integration
    • Bushman F, Lewinski M, Ciuffi A, et al. Genome-wide analysis of retroviral DNA integration. Nat Rev Microbiol 2005; 3: 848-858.
    • (2005) Nat Rev Microbiol , vol.3 , pp. 848-858
    • Bushman, F.1    Lewinski, M.2    Ciuffi, A.3
  • 6
    • 19344375031 scopus 로고    scopus 로고
    • Retroviral DNA integration: ASLV, HIV, and MLV show distinct target site preferences
    • Mitchell RS, Beitzel BF, Schroder AR, et al. Retroviral DNA integration: ASLV, HIV, and MLV show distinct target site preferences. PLoS Biol 2004; 2: E234.
    • (2004) PLoS Biol , vol.2
    • Mitchell, R.S.1    Beitzel, B.F.2    Schroder, A.R.3
  • 7
    • 33847408501 scopus 로고    scopus 로고
    • Retroviral vector insertion sites associated with dominant hematopoietic clones mark 'stemness' pathways
    • Kustikova OS, Geiger H, Li Z, et al. Retroviral vector insertion sites associated with dominant hematopoietic clones mark 'stemness' pathways. Blood 2007; 109: 1897-1907.
    • (2007) Blood , vol.109 , pp. 1897-1907
    • Kustikova, O.S.1    Geiger, H.2    Li, Z.3
  • 8
    • 34250851635 scopus 로고    scopus 로고
    • Comparison of HIV-derived lentiviral and MLV-based gammaretroviral vector integration sites in primate repopulating cells
    • Beard BC, Dickerson D, Beebe K, et al. Comparison of HIV-derived lentiviral and MLV-based gammaretroviral vector integration sites in primate repopulating cells. Mol Ther 2007; 15: 1356-1365.
    • (2007) Mol Ther , vol.15 , pp. 1356-1365
    • Beard, B.C.1    Dickerson, D.2    Beebe, K.3
  • 10
    • 0032118427 scopus 로고    scopus 로고
    • Wiskott-Aldrich syndrome protein-deficient mice reveal a role for WASP in T but not B cell activation
    • Snapper SB, Rosen FS, Mizoguchi E, et al. Wiskott-Aldrich syndrome protein-deficient mice reveal a role for WASP in T but not B cell activation. Immunity 1998; 9: 81-91.
    • (1998) Immunity , vol.9 , pp. 81-91
    • Snapper, S.B.1    Rosen, F.S.2    Mizoguchi, E.3
  • 11
    • 0142084745 scopus 로고    scopus 로고
    • LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1
    • Hacein-Bey-Abina S, Von Kalle C, Schmidt M, et al. LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1. Science 2003; 302: 415-419.
    • (2003) Science , vol.302 , pp. 415-419
    • Hacein-Bey-Abina, S.1    Von Kalle, C.2    Schmidt, M.3
  • 12
    • 33645451483 scopus 로고    scopus 로고
    • Mutagenesis and oncogenesis by chromosomal insertion of gene transfer vectors
    • Baum C, Kustikova O, Modlich U, Li Z, Fehse B. Mutagenesis and oncogenesis by chromosomal insertion of gene transfer vectors. Hum Gene Ther 2006; 17: 253-263.
    • (2006) Hum Gene Ther , vol.17 , pp. 253-263
    • Baum, C.1    Kustikova, O.2    Modlich, U.3    Li, Z.4    Fehse, B.5
  • 13
    • 47049119980 scopus 로고    scopus 로고
    • Genotypic features of lentiviral transgenic mice
    • Sauvain MO, Dorr AP, Stevenson B, et al. Genotypic features of lentiviral transgenic mice. J Virol 2008; 82: 7111-7119.
    • (2008) J Virol , vol.82 , pp. 7111-7119
    • Sauvain, M.O.1    Dorr, A.P.2    Stevenson, B.3
  • 14
    • 44349171666 scopus 로고    scopus 로고
    • Role of PSIP1/LEDGF/p75 in lentiviral infectivity and integration targeting
    • Marshall HM, Ronen K, Berry C, et al. Role of PSIP1/LEDGF/p75 in lentiviral infectivity and integration targeting. PLoS ONE 2007; 2: E1340.
    • (2007) PLoS ONE , vol.2
    • Marshall, H.M.1    Ronen, K.2    Berry, C.3
  • 15
    • 34547657665 scopus 로고    scopus 로고
    • Hot spots of retroviral integration in human CD34+ hematopoietic cells
    • Cattoglio C, Facchini G, Sartori D, et al. Hot spots of retroviral integration in human CD34+ hematopoietic cells. Blood 2007; 110: 1770-1778.
    • (2007) Blood , vol.110 , pp. 1770-1778
    • Cattoglio, C.1    Facchini, G.2    Sartori, D.3
  • 16
    • 33745108790 scopus 로고    scopus 로고
    • Hematopoietic stem cell gene transfer in a tumor-prone mouse model uncovers low genotoxicity of lentiviral vector integration
    • Montini E, Cesana D, Schmidt M, et al. Hematopoietic stem cell gene transfer in a tumor-prone mouse model uncovers low genotoxicity of lentiviral vector integration. Nat Biotechnol 2006; 24: 687-696.
    • (2006) Nat Biotechnol , vol.24 , pp. 687-696
    • Montini, E.1    Cesana, D.2    Schmidt, M.3
  • 17
    • 67349202780 scopus 로고    scopus 로고
    • Validation of a mutated PRE sequence allowing high and sustained transgene expression while abrogating WHV-X protein synthesis: Application to the gene therapy of WAS
    • Mar 5 [Epub ahead of print
    • Zanta-Boussif MA, Charrier S, Brice-Ouzet A, et al. Validation of a mutated PRE sequence allowing high and sustained transgene expression while abrogating WHV-X protein synthesis: application to the gene therapy of WAS. Gene Ther 2009; Mar 5 [Epub ahead of print].
    • (2009) Gene Ther
    • Zanta-Boussif, M.A.1    Charrier, S.2    Brice-Ouzet, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.