Enantiomeric separation of D- and L-serine using high-performance liquid chromatography with electrochemical detection following pre-column diastereomer derivatization

Biomedical Chromatography

Volumn 23, Issue 8, 2009, Pages 793-797

  Yamashita, Kazuhide ^a   Fukushima, Takeshi ^a,b   Sasaki, Tsukasa ^a   Arai, Kotaro ^a   Toyo'oka, Toshimasa ^a  

^a UNIVERSITY OF SHIZUOKA   (Japan)

^b TOHO UNIVERSITY   (Japan)

Author keywords

D serine; Derivatization; Diastereomer; Electrochemical detection; HPLC; L serine

Indexed keywords

AMINO ACIDS; CARBOXYLATION; CHEMICAL DETECTION; COLUMN CHROMATOGRAPHY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SIGNAL TO NOISE RATIO;

D-SERINE; DERIVATIZATION REAGENT; DERIVATIZATIONS; DIASTEREOMERS; ELECTROCHEMICAL DETECTION; ELUTION ORDER; ENANTIOMERIC SEPARATION; HPLC; L-SERINE; TETRAMETHYL;

ENANTIOMERS;

2,5 DIOXOPYRROLIDIN 1 YL 2,5,7,8 TETRAMETHYL 6 (TETRAHYDRO 2H PYRAN 2 YLOXY)CHROMAN 2 CARBOXYLATE; BUFFER; CARBOXYLIC ACID; DEXTRO SERINE; PHOSPHATE; SERINE; UNCLASSIFIED DRUG;

ARTICLE; ELECTROCHEMICAL DETECTION; ELUTION; ENANTIOMERIC SEPARATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYDROLYSIS; HYDROPHOBICITY; PHASE SEPARATION; SEPARATION TECHNIQUE;

EID: 70349498678     PISSN: 02693879     EISSN: 10990801     Source Type: Journal    
DOI: 10.1002/bmc.1196     Document Type: Article

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