Desmoplastic cellular neurothekeoma: Clinicopathological analysis of twelve cases

Journal of Cutaneous Pathology

Volumn 36, Issue 11, 2009, Pages 1185-1190

  Zedek, Daniel C ^a   White, Wain L ^b,c,d   McCalmont, Timothy H ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b WAKE FOREST SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF NORTH CAROLINA HOSPITALS   (United States)

^d Greensboro Pathology Associates   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD68 ANTIGEN; LAMININ; NEUROKININ 1 RECEPTOR;

ABDOMEN; ADOLESCENT; ADULT; ARM; ARTICLE; CELLULAR NEUROTHEKEOMA; CHILD; CLINICAL ARTICLE; CYTOARCHITECTURE; DERMATOFIBROMA; DIFFERENTIAL DIAGNOSIS; FEMALE; HEAD AND NECK TUMOR; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; LEG; MALE; NERVE TUMOR; NEUROTHEKEOMA; SCAR; SPINDLE CELL CARCINOMA; TRICHILEMMOMA; TRUNK;

ADOLESCENT; ADULT; CHILD; CHILD, PRESCHOOL; DIAGNOSIS, DIFFERENTIAL; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MIDDLE AGED; NEUROTHEKEOMA; SKIN NEOPLASMS; YOUNG ADULT;

EID: 70349498413     PISSN: 03036987     EISSN: 16000560     Source Type: Journal    
DOI: 10.1111/j.1600-0560.2009.01263.x     Document Type: Article

References (29)

1. Argenyi Z, LeBoit P, Santa Cruz D, Swanson P, Kutzner H. Nerve sheath myxoma (neurothekeoma) of the skin: light microscopic and immunohistochemical reappraisal of the cellular variant. J Cutan Pathol 1993 20 : 294.
2. Gallagher R, Helwig E. Neurothekeoma- benign cutaneous tumor of neural origin. Am J Clin Pathol 1980 74 : 759.
3. Pulitzer D, Reed R. Nerve-sheath myxoma (perineurial myxoma). Am J Dermatopathol 1985 7 : 409.
4. Hornick J, Fletcher C. Cellular neurothekeoma: detailed characterization in a series of 133 cases. Am J Surg Pathol 2007 31 : 329.
5. Barnhill R. Nerve sheath myxoma (neuroth ekeoma). J Cutan Pathol 1994 21 : 91.
6. Fetsch J, Laskin W, Hallman J, Lupton G, Miettinen M. Neurothekeoma: an analysis of 178 tumors with detailed immunohistochemical data and long-term patient follow-up information. Am J Surg Pathol 2007 31 : 1103.
7. Wang A, May D, Bourne P, et al. PGP9.5. A marker for cellular neurothekeoma. Am J Surg Pathol 1999 23 : 1401.
8. Zelger BG, Steiner H, Kutzner H, Maier H, Zelger B. Cellular 'neurothekeoma': an epithelioid variant of dermatofibroma? Histopathology 1998 32 : 414.
9. Mahalingham M, Alter J, Bhawan J. Multiple cellular neurothekeomas - a case report and review on the role of immunohistochemistry as a histologic adjunct. J Cutan Pathol 2006 33 : 51.
10. Fetsch J, Laskin W, Miettinen M. Nerve sheath myxoma: a clinicopathologic and immunohistochemical analysis of 57 morphologically distinctive, S-100 protein- and GFAP-positive, myxoid peripheral nerve sheath tumors with a predilection for the extremities and a high local recurrence rate. Am J Surg Pathol 2005 29 : 1615.
11. Busam K, Mentzel T, Colpaert C, Barnhill R, Fletcher C. Atypical or worrisome features in cellular neurothekeoma: a study of 10 cases. Am J Surg Pathol 1998 22 : 1067.
12. Page R, King R, Mihm M, Googe P. Microphthalmia transcription factor and NKI/C3 expression in cellular neurothekeoma. Mod Pathol 2004 17 : 230.
13. Sachdev R, Sundram U. Frequent positive staining with NKI/C3 in normal and neoplastic tissues limits its usefulness in the diagnosis of cellular neurothekeoma. Am J Clin Pathol 2006 126 : 1.
14. Argenyi Z, Kutzner H, Seaba M. Ultrastructural spectrum of cutaneous nerve sheath myxoma/cellular neurothekeoma. J Cutan Pathol 1995 22 : 137.
15. Barnhill R, Dickersin G, Nickeleit V, et al. Studies on the cellular origin of neurothekeoma: clinical, light microscopic, immunohistochemical, and ultrastructural observations. J Am Acad Dermatol 1991 25 : 80.
16. Chang S, Lee T Ro J, et al. Cellular neurothekeoma with possible neuroendocrine differentiation. J Dermatol 1999 26 : 363.
17. Jain S, Allen P. Desmoplastic melanoma and its variants: a study of 45 cases. Am J Surg Pathol 1989 13 : 358.
18. Evans H, Smith J. Spindle cell squamous carcinomas and sarcoma-like tumors of the skin. A comparative study of 38 cases. Cancer 1980 45 : 2687.
19. de Feraudy S, Mar N, McCalmont T. Evaluation of CD10 and procollagen 1 expression in atypical fibroxanthoma and dermatofibroma. Am J Surg Pathol 2008 32 : 1111.
20. Enzinger F, Zhang R. Plexiform fibrohistiocytic tumor presenting in children and young adults: an analysis of 65 cases. Am J Surg Pathol 1988 12 : 818.
21. Remstein E, Arndt C, Nascimento A. Plexiform fibrohistiocytic tumor: clinicopathologic analysis of 22 cases. Am J Surg Pathol 1999 22 : 662.
22. Zelger B, Weinlich G, Steiner H, Zelger BG, Egarter-Vigl E. Dermal and subcutaneous variants of plexiform fibrohistiocytic tumor. Am J Surg Pathol 1997 21 : 235.
23. Hollowood K, Holley M, Fletcher C. Plexiform fibrohistiocytic tumor: Clinicopathological, immunohistochemical, and ultrastructural analysis in favor of myofibroblastic lesion. Histopathology 1991 19 : 503.
24. Salamao D, Nascimento A. Plexiform fibrohistiocytic tumor with systemic metastases: a case report. Am J Surg Pathol 1997 21 : 469.
25. Bilbao J, Khoury N, Hudson A, Briggs S. Perineurioma (localized hypertrophic neuropathy). Arch Pathol Lab Med 1984 108 : 557.
26. Mentzel T, Dei Tos A, Fletcher C. Perineurioma (storiform perineurial fibroma): clinicopathological analysis of four cases. Histopathology 1994 25 : 261.
27. Robson A, Calonje E. Cutaneous perineurioma: a poorly recognized tumour often misdiagnosed as epithelioid histiocytoma. Histopathology 2000 37 : 332.
28. Fetsch J, Miettinen M. Sclerosing perineurioma: a clinicopathological study of 19 cases of a distinctive soft tissue lesion with a predilection for the fingers and palms of young adults. Am J Surg Pathol 1997 21 : 1433.
29. Raj S, Calonje E, Kraus M, Kavanagh G, Newman P, Fletcher C. Cutaneous pilar leiomyoma: clinicopathologic analysis of 53 lesions in 45 patients. Am J Dermatopathol 1997 19 : 2.