Renal cell apoptosis in human lupus nephritis: A histological study

Lupus

Volumn 18, Issue 11, 2009, Pages 994-999

  Faurschou, Mikkel ^a   Penkowa, M ^b   Andersen, C B ^a   Starklint, H ^c   Jacobsen, S ^a  

^a University of Copenhagen   (Denmark)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

^c LILLEBAELT HOSPITAL   (Denmark)

Author keywords

Apoptosis; Histology; Lupus nephritis; Systemic lupus erythematosus; TUNEL

Indexed keywords

ADULT; APOPTOSIS; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; FEMALE; HISTOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; INTERSTITIAL NEPHRITIS; KIDNEY BIOPSY; KIDNEY TUBULE CELL; LUPUS ERYTHEMATOSUS NEPHRITIS; LYMPHOCYTIC INFILTRATION; MALE; MONONUCLEAR CELL; NICK END LABELING; PRIORITY JOURNAL; SYSTEMIC LUPUS ERYTHEMATOSUS;

ADULT; APOPTOSIS; DNA FRAGMENTATION; FEMALE; HUMANS; IN SITU NICK-END LABELING; KIDNEY; KIDNEY TUBULES; LUPUS ERYTHEMATOSUS, SYSTEMIC; LUPUS NEPHRITIS; YOUNG ADULT;

EID: 70349487987     PISSN: 09612033     EISSN: None     Source Type: Journal    
DOI: 10.1177/0961203309106175     Document Type: Article

References (29)

1. Berden JH. Lupus nephritis: Consequence of disturbed removal of apoptotic cells? Neth J Med 2003; 61: 233-238.
2. van Bavel CC, Fenton KA, Rekvig OP, van der Vlag V, Berden JH. Glomerular targets of nephritogenic autoantibodies in systemic lupus erythematosus. Arthritis Rheum 2008; 58: 1892-1899.
3. Muller S, Dieker J, Tincani A, Meroni PL. Pathogenic anti-nucleosome antibodies. Lupus 2008; 17: 431-436.
4. Cameron JS. Lupus nephritis. J Am Soc Nephrol 1999; 10: 413-424.
5. Faurschou M, Starklint H, Halberg P, Jacobsen S. Prognostic factors in lupus nephritis: Diagnostic and therapeutic delay increases the risk of terminal renal failure. J Rheumatol 2006; 33: 1563-1569.
6. MacGowan JR, Ellis S, Griffiths M, Isenberg DA. Retrospective analysis of outcome in a cohort of patients with lupus nephritis treated between 1977 and 1999. Rheumatology (Oxford) 2002; 41: 981-987.
7. Martins L, Rocha G, Rodrigues A, et al. Lupus nephritis: A retrospective review of 78 cases from a single center. Clin Nephrol 2002; 57: 114-119.
8. Kalaaji M, Fenton KA, Mortensen ES. Glomerular apoptotic nucleosomes are central target structures for nephritogenic antibodies in human SLE nephritis. Kidney Int 2007; 71: 664-672.
9. Fenton KA, Mjelle JE, Jakobsen S, Olsen R, Rekvig OP. Renal expression of polyomavirus large T antigen is associated with nephritis in human systemic lupus erythematosus. Mol Immunol 2008; 45: 3117-3124.
10. Makino H, Sugiyama H, Yamasaki Y, Maeshima Y, Wada J, Kashihara N. Glomerular cell apoptosis in human lupus nephritis. Virchows Arch 2003; 443: 67-77.
11. Jeruc J, Vizjak A, Rozman B, Ferluga D. Immunohistochemical expression of activated caspase-3 as a marker of apoptosis in glomeruli of human lupus nephritis. Am J Kidney Dis 2006; 48: 410-418.
12. Zheng L, Sinniah R, Hsu SI. Renal cell apoptosis and proliferation may be linked to nuclear factor-kappaB activation and expression of inducible nitric oxide synthase in patients with lupus nephritis. Hum Pathol 2006; 37: 637-647.
13. Wagrowska-Danilewicz M, Danilewicz M. Apoptosis in lupus SLE-N IV and non-lupus mesangiocapillary glomerulonephritis type I MCGN. I. A comparative study. J Nephrol 1998; 11: 44-49.
14. Soto H, Mosquera J, Rodriguez-Iturbe B, Henriquez LR, Pinto A. Apoptosis in proliferative glomerulonephritis: Decreased apoptosis expression in lupus nephritis. Nephrol Dial Transplant 1997; 12: 273-280.
15. Lu F, Shen W, Zhang X, Guo M, Lin S. Dysregulation of apoptosis: A possible mechanism leading to chronic progressive renal histological changes in lupus nephritis. Chin Med J (Engl) 2000; 113: 1082-1086.
16. Tan EM, Cohen AS, Fries JF, et al. The 1982 revised criteria for the classification of systemic lupus erythematosus. Arthritis Rheum 1982; 25: 1271-1277.
17. Vitali C, Bencivelli W, Isenberg DA, et al. Disease activity in systemic lupus erythematosus: Report of the Consensus Study Group of the European Workshop for Rheumatology Research. I. A descriptive analysis of 704 European lupus patients. European Consensus Study Group for disease activity in SLE. Clin Exp Rheumatol 1992; 10: 527-539.
18. Churg J, Sobin LH. Renal disease: Classification and atlas of glomerular disease. Tokyo: Igaku-Shoin; 1982. pp. 127-131.
19. Austin HA, Muenz LR, Joyce KM, et al. Prognostic factors in lupus nephritis. Contribution of renal histologic data. Am J Med 1983; 75: 382-391.
20. Grootscholten C, van Bruggen MC, van der Pijl JW, et al. Deposition of nucleosomal antigens (histones and DNA) in the epidermal basement membrane in human lupus nephritis. Arthritis Rheum 2003; 48: 1355-1362.
21. Williams RC, Malone CC, Meyers C, Decker P, Muller S. Detection of nucleosome particles in serum and plasma from patients with systemic lupus erythematosus using monoclonal antibody 4H7. J Rheumatol 2001; 28: 81-94.
22. Fismen S, Hedberg A, Fenton KA, et al. Circulating chromatin-anti-chromatin antibody complexes bind with high affinity to dermo-epidermal structures in murine and human lupus nephritis. Lupus 2009; 18: 597-607.
23. Kalaaji M, Mortensen E, Jorgensen L, Olsen R, Rekvig OP. Nephritogenic lupus antibodies recognize glomerular basement membrane-associated chromatin fragments released from apoptotic intraglomerular cells. Am J Pathol 2006; 168: 1779-1792.
24. Noronha IL, Oliveira SG, Tavares TS, et al. Apoptosis in kidney and pancreas allograft biopsies. Transplantation 2005; 79: 1231-1235.
25. Austin HA, Boumpas DT, Vaughan EM, Balow JE. Predicting renal outcomes in severe lupus nephritis: Contributions of clinical and histologic data. Kidney Int 1994; 45: 544-550.
26. Austin III HA, Boumpas DT, Vaughan EM, Balow JE. High-risk features of lupus nephritis: Importance of race and clinical and histological factors in 166 patients. Nephrol Dial Transplant 1995; 10: 1620-1628.
27. Conlon PJ, Fischer CA, Levesque MC, et al. Clinical, biochemical and pathological predictors of poor response to intravenous cyclophosphamide in patients with proliferative lupus nephritis. Clin Nephrol 1996; 46: 170-175.
28. Watanabe M, Hitomi M, van der WK, et al. The pros and cons of apoptosis assays for use in the study of cells, tissues, and organs. Microsc Microanal 2002; 8: 375-391.
29. Huerta S, Goulet EJ, Huerta-Yepez S, Livingston EH. Screening and detection of apoptosis. J Surg Res 2007; 139: 143-156.