Variation of barrier permeability for albumin and immunoglobulin G influx into cerebrospinal fluid

Clinical Chemistry and Laboratory Medicine

Volumn 47, Issue 8, 2009, Pages 955-958

  Seyfert, Sepp ^a   Quill, Sabine ^a   Faulstich, Andreas ^a  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

Albumin; Barrier permeability; Cerebrospinal fluid (CSF); Immunoglobulin G (IgG); Intra individual variation

Indexed keywords

ALBUMIN; IMMUNOGLOBULIN G;

ARTICLE; BLOOD CEREBROSPINAL FLUID BARRIER; CEREBROSPINAL FLUID; CONTROLLED STUDY; DIFFUSION; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; PERMEABILITY; PRIORITY JOURNAL;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; ALBUMINS; BLOOD-BRAIN BARRIER; FEMALE; HUMANS; IMMUNOGLOBULIN G; MALE; MIDDLE AGED; RETROSPECTIVE STUDIES; YOUNG ADULT;

EID: 70349484949     PISSN: 14346621     EISSN: 14374331     Source Type: Journal    
DOI: 10.1515/CCLM.2009.211     Document Type: Article

References (14)

1. Cutler RW, Deuel RK, Barlow CF. Albumin exchange between plasma and cerebrospinal fluid. Arch Neurol 1967;17:261-270
2. Cutler RW, Watters G, Hammerstad P. The origin and turnover rates of cerebrospinal fluid albumin and gammaglobulin in man. J Neurol Sci 1970;10:259-268
3. Felgenhauer K. Protein size and cerebrospinal fluid composition. Klin Wschr 1974;52:1158-1164
4. Davson H, Hollingsworth G, Segal MB. The mechanism of drainage of the cerebrospinal fluid. Brain 1970;93: 665-678
5. Nau R, Emrich D, Prange HW. Inverse correlation between disappearance of intrathecally injected 111In- DTPA from CSF with CSF protein content and CSF-toserum albumin ratio. J Neurol Sci 1993;115:102-104
6. Bozzao A, Floris R, Fasoli F, Fantozzi LM, Colonnese C, Simonetti G. Cerebrospinal fluid changes after intravenous injection of gadolinium chelate: assessment by FLAIR MR imaging. Eur Radiol 2003;13:592-597
7. Seyfert S, Becher A, Ohring R, Faulstich A. The permeability of the blood-CSF barrier in hydrocephalus, polyradiculitis, and meningitis. J Neurol 2004;25:355-356
8. Lee KY, Lee JS. Immunoglobulin G has a role for systemic protein modulation in vivo: a new concept of protein homeostasis. Med Hypotheses 2006;67:848-855
9. Renkin E. Transport of large molecules across capillary walls. Physiologist 1964;7:13-28.
10. Felgenhauer K, Schliep G, Rapic N. Evaluation of the blood-CSF barrier by protein gradients and the humoral immune response within the central nervous system. J Neurol Sci 1976;30:113-128
11. van Deurs B. Structural aspects of brain barriers, with special reference to the permeability of the cerebral endothelium and choroidal epithelium. Int Rev Cytol 1980;65:117-191
12. Hawkins BT, Davis TP. The blood-brain barrier/neurovascular unit in health and disease. Pharmacol Rev 2005;57: 173-185
13. Kapoor KG, Katz SE, Grzybowski DM, Lubow M. Cerebrospinal fluid outflow: an evolving perspective. Brain Res Bull 2008;77:327-334
14. Schlachetzki F, Zhu C, Pardridge WM. Expression of the neonatal Fc receptor (FcRn) at the blood-brain barrier. J Neurochem 2002;81:203-206 (Pubitemid 34808868)