Stability of the JP2 clone of aggregatibacter actinomycetemcomitans

Journal of Dental Research

Volumn 88, Issue 9, 2009, Pages 856-860

  Haubek, D ^a   Ennibi, O K ^d   Vaeth M ^c   Poulsen, S ^a   Poulsen, K ^b  

^a School of Dentistry   (Denmark)

^b Wilhelm Meyers Alĺ ^*  (Denmark)

^c AARHUS UNIVERSITY   (Denmark)

^d Dental Faculty   (United States)

Author keywords

Aggressive periodontitis; Competitive exclusion; Highly leukotoxic; Infection dynamics; Leukotoxin

Indexed keywords

ACTINOBACILLUS ACTINOMYCETEMCOMITANS; ACTINOBACILLUS INFECTION; ARTICLE; CELL CLONE; CHILD; DISEASE COURSE; FEMALE; FOLLOW UP; GENETICS; GENOTYPE; HOST PATHOGEN INTERACTION; HUMAN; LONGITUDINAL STUDY; MALE; MICROBIOLOGY; MOROCCO; PATHOGENICITY; PATHOPHYSIOLOGY; PERIODONTAL DISEASE; PERIODONTITIS; PHYSIOLOGY; RISK FACTOR; TOOTH PLAQUE;

ACTINOBACILLUS ACTINOMYCETEMCOMITANS; ACTINOBACILLUS INFECTIONS; AGGRESSIVE PERIODONTITIS; CHILD; CLONE CELLS; DENTAL PLAQUE; DISEASE PROGRESSION; FEMALE; FOLLOW-UP STUDIES; GENOTYPE; HOST-PATHOGEN INTERACTIONS; HUMANS; LONGITUDINAL STUDIES; MALE; MOROCCO; PERIODONTAL ATTACHMENT LOSS; PERIODONTAL POCKET; RISK FACTORS;

EID: 70349481491     PISSN: 00220345     EISSN: None     Source Type: Journal    
DOI: 10.1177/0022034509342190     Document Type: Article

References (15)

1. Bek-Thomsen M., Tettelin H., Hance I., Nelson KE, Kilian M. (2008). Population diversity and dynamics of Streptococcus mitis, Streptococcus oralis, and Streptococcus infantitis in the upper respiratory tract of adults, determined by a nonculture strategy. Infect Immun 76: 1889-1896.
2. Brogan JM, Lally ET, Poulsen K., Kilian M., Demuth DR (1994). Regulation of Actinobacillus actinomycetemcomitans leukotoxin expression: analysis of the promoter regions of leukotoxic and minimally leukotoxic strains. Infect Immun 62: 501-508.
3. Bueno LC, Mayer MP, DiRienzo JM (1998). Relationship between conversion of localized juvenile periodontitis-susceptible children from health to disease and Actinobacillus actinomycetemcomitans leukotoxin promoter structure. J Periodontol 69: 998-1007 ; erratum in J Periodontol 70: 822, 1999.
4. Cortelli JR, Cortelli SC, Jordan S., Haraszthy VI, Zambon JJ (2005). Prevalence of periodontal pathogens in Brazilians with aggressive or chronic periodontitis. J Clin Periodontol 32: 860-866.
5. Guthmiller JM, Lally ET, Korostoff J. (2001). Beyond the specific plaque hypothesis: are highly leukotoxic strains of Actinobacillus actinomycetemcomitans a paradigm for periodontal pathogenesis ? Crit Rev Oral Biol Med 12: 116-124.
6. Haraszthy VI, Hariharan G., Tinoco EM, Cortelli JR, Lally ET, Davis E., et al. (2000). Evidence for the role of highly leukotoxic Actinobacillus actinomycetemcomitans in the pathogenesis of localized juvenile and other forms of early-onset periodontitis. J Periodontol 71: 912-922.
7. Haubek D., Ennibi OK, Poulsen K., Poulsen S., Benzarti N., Kilian M. (2001). Early-onset periodontitis in Morocco is associated with the highly leukotoxic clone of Actinobacillus actinomycetemcomitans. J Dent Res 80: 1580-1583.
8. Haubek D., Ennibi OK, Poulsen K., Benzarti N., Baelum V. (2004). The highly leukotoxic JP2 clone of Actinobacillus actinomycetemcomitans and progression of periodontal attachment loss. J Dent Res 83: 767-770.
9. Haubek D., Ennibi O. -K, Poulsen K., Vaeth M., Poulsen S., Kilian M. (2008). Risk of aggressive periodontitis in adolescent carriers of the JP2 clone of Aggregatibacter (Actinobacillus) actinomycetemcomitans in Morocco: a prospective longitudinal cohort study. Lancet 371: 237-242.
10. Kilian M., Frandsen EV, Haubek D., Poulsen K. (2006). The etiology of periodontal disease revisited by population genetic analysis. Periodontol 2000 42: 158-179.
11. Lopez R., Baelum V. (2003). Classifying periodontitis among adolescents: implications for epidemiological research. Community Dent Oral Epidemiol 31: 136-143.
12. Poulsen K., Ennibi OK, Haubek D. (2003). Improved PCR for detection of the highly leukotoxic JP2 clone of Actinobacillus actinomycetemcomitans in subgingival plaque samples. J Clin Microbiol 41: 4829-4832.
13. Saarela MH, Asikainen S., Alaluusua S., PyhÁCurrency signlÁCurrency sign L., Lai C. - H. Jousimies - Somer H. (1992). Frequency and stability of mono and poly-infection by Actinobacillus actinomycetemcomitans serotypes a, b, c, d, or e. Oral Microbiol Immunol 7: 277-279.
14. Saarela MH, Dogan B., Alaluusua S., Asikainen S. (1999). Persistence of oral colonization by the same Actinobacillus actinomycetemcomitans strain(s). J Periodontol 70: 504-509.
15. van der Reijden WA, Bosch-Tijhof CJ, van der Velden U., van Winkelhoff AJ (2008). Java project on periodontal diseases: serotype distribution of Aggregatibacter actinomycetemcomitans and serotype dynamics over an 8-year period. J Clin Periodontol 35: 487-492.