Persistent arterial stiffness and endothelial dysfunction following successful pancreas-kidney transplantation in Type 1 diabetes

Diabetic Medicine

Volumn 26, Issue 10, 2009, Pages 1010-1018

  Stadler, M ^a,b   Theuer, E ^b   Anderwald, C ^c   Hanusch Enserer, U ^a   Auinger, M ^a   Bieglmayer, C ^c   Quehenberger, P ^c   Bischof, M ^c   Kastenbauer T ^b   Wolzt, M ^c   Wagner, O ^c   Prager, R ^a,b  

^a Hietzing Hospital   (Austria)

^b Karl Landsteiner Institute for Endocrinology and Metabolism   (Austria)

^c MEDICAL UNIVERSITY OF VIENNA   (Austria)

Author keywords

Adhesion molecules; Pancreas transplantation; Pulse wave velocity; Type 1 diabetes

Indexed keywords

AZATHIOPRINE; CELL ADHESION MOLECULE; CYCLOSPORIN A; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; TACROLIMUS; VASCULAR CELL ADHESION MOLECULE 1;

ADULT; ARTERIAL STIFFNESS; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; ENDOTHELIAL DYSFUNCTION; FEMALE; HEART RATE; HEART STROKE VOLUME; HUMAN; INSULIN DEPENDENT DIABETES MELLITUS; KIDNEY PANCREAS TRANSPLANTATION; MALE; PULSE WAVE; SYSTOLIC BLOOD PRESSURE; TREATMENT OUTCOME;

ADULT; AGED; AGED, 80 AND OVER; ATHEROSCLEROSIS; BLOOD FLOW VELOCITY; CASE-CONTROL STUDIES; DIABETES MELLITUS, TYPE 1; DIABETIC ANGIOPATHIES; E-SELECTIN; ENDOTHELIUM, VASCULAR; FEMALE; HEART RATE; HUMANS; KIDNEY TRANSPLANTATION; MALE; MIDDLE AGED; PANCREAS TRANSPLANTATION; PLASMINOGEN ACTIVATOR INHIBITOR 1; STROKE VOLUME; TREATMENT OUTCOME; VASCULAR CELL ADHESION MOLECULE-1; YOUNG ADULT;

EID: 70349479582     PISSN: 07423071     EISSN: 14645491     Source Type: Journal    
DOI: 10.1111/j.1464-5491.2009.02817.x     Document Type: Article

References (50)

1. Stadler M, Anderwald C, Karer T, Tura A, Kastenbauer T, Auinger M et al. Increased plasma amylin in type 1 diabetic patients after kidney and pancreas transplantation: A sign of impaired beta-cell function? Diabetes Care 2006; 29(5): 1031-1038.
2. Biesenbach G, Margreiter R, Konigsrainer A, Bosmuller C, Janko O, Brucke P et al. Comparison of progression of macrovascular diseases after kidney or pancreas and kidney transplantation in diabetic patients with end-stage renal disease. Diabetologia 2000; 43(2): 231-234.
3. Tyden G, Bolinder J, Solders G, Brattstrom C, Tibell A, Groth CG et al. Improved survival in patients with insulin-dependent diabetes mellitus and end-stage diabetic nephropathy 10 years after combined pancreas and kidney transplantation. Transplantation 1999; 67(5): 645-648.
4. Fiorina P, La Rocca E, Venturini M, Minicucci F, Fermo I, Paroni R et al. Effects of kidney-pancreas transplantation on atherosclerotic risk factors and endothelial function in patients with uremia and type 1 diabetes. Diabetes 2001; 50(3): 496-501.
5. Blacher J, Asmar R, Djane S, London GM, Safar ME. Aortic pulse wave velocity as a marker of cardiovascular risk in hypertensive patients. Hypertension 1999; 33(5): 1111-1117.
6. Cruickshank K, Riste L, Anderson SG, Wright JS, Dunn G, Gosling RG et al. Aortic pulse-wave velocity and its relationship to mortality in diabetes and glucose intolerance: an integrated index of vascular function? Circulation 2002; 106(16): 2085-2090.
7. Zoungas S, Kerr PG, Chadban S, Muske C, Ristevski S, Atkins RC et al. Arterial function after successful renal transplantation. Kidney Int 2004; 65(5): 1882-1889.
8. Sweitzer NK, Shenoy M, Stein JH, Keles S, Palta M, LeCaire T et al. Increases in central aortic impedance precede alterations in arterial stiffness measures in type 1 diabetes. Diabetes Care 2007; 30(11): 2886-2891.
9. Koobi T, Kahonen M, Iivainen T, Turjanmaa V. Simultaneous non-invasive assessment of arterial stiffness and haemodynamics - a validation study. Clin Physiol Funct Imaging 2003; 23(1): 31-36.
10. Gusso S, Hofman P, Lalande S, Cutfield W, Robinson E, Baldi JC et al. Impaired stroke volume and aerobic capacity in female adolescents with type 1 and type 2 diabetes mellitus. Diabetologia 2008; 51(7): 1317-1320.
11. Moshkovitz Y, Kaluski E, Milo O, Vered Z, Cotter G. Recent developments in cardiac output determination by bioimpedance: comparison with invasive cardiac output and potential cardiovascular applications. Curr Opin Cardiol 2004; 19(3): 229-237.
12. Gokce N, Keaney JF Jr, Hunter LM, Watkins MT, Nedeljkovic ZS, Menzoian JO et al. Predictive value of noninvasively determined endothelial dysfunction for long-term cardiovascular events in patients with peripheral vascular disease. J Am Coll Cardiol 2003; 41(10): 1769-1775.
13. Silva JA, Escobar A, Collins TJ, Ramee SR, White CJ. Unstable angina. A comparison of angioscopic findings between diabetic and nondiabetic patients. Circulation 1995; 92(7): 1731-1736.
14. Goldberg IJ. Why does diabetes increase atherosclerosis? I don't know! J Clin Invest 2004; 114(5): 613-615.
15. Nigro J, Osman N, Dart AM, Little PJ. Insulin resistance and atherosclerosis. Endocr Rev 2006; 27(3): 242-259.
16. Moens AL, Goovaerts I, Claeys MJ, Vrints CJ. Flow-mediated vasodilation: a diagnostic instrument, or an experimental tool? Chest 2005; 127(6): 2254-2263.
17. Astrup AS, Tarnow L, Pietraszek L, Schalkwijk CG, Stehouwer CD, Parving HH et al. Markers of endothelial dysfunction and inflammation in type 1 diabetic patients with or without diabetic nephropathy followed for 10 years: association with mortality and decline of glomerular filtration rate. Diabetes Care 2008; 31(6): 1170-1176.
18. Fasching P, Waldhausl W, Wagner OF. Elevated circulating adhesion molecules in NIDDM-potential mediators in diabetic macroangiopathy. Diabetologia 1996; 39(10): 1242-1244.
19. Anderson TJ, Uehata A, Gerhard MD, Meredith IT, Knab S, Delagrange D et al. Close relation of endothelial function in the human coronary and peripheral circulations. J Am Coll Cardiol 1995; 26(5): 1235-1241.
20. American Diabetes Association. Standards of medical care in diabetes-2006. Diabetes Care 2006; 29 Suppl 1:S4-42.
21. Koobi T, Kaukinen S, Ahola T, Turjanmaa VM. Non-invasive measurement of cardiac output: whole-body impedance cardiography in simultaneous comparison with thermodilution and direct oxygen Fick methods. Intensive Care Med 1997; 23(11): 1132-1137.
22. Oliver JJ, Webb DJ. Noninvasive assessment of arterial stiffness and risk of atherosclerotic events. Arterioscler Thromb Vasc Biol 2003; 23(4): 554-566.
23. Osypka MJ, Bernstein DP. Electrophysiologic principles and theory of stroke volume determination by thoracic electrical bioimpedance. AACN Clin Issues 1999; 10(3): 385-399.
24. Stadler M, Auinger M, Anderwald C, Kastenbauer T, Kramar R, Feinbock C et al. Long-term mortality and incidence of renal dialysis and transplantation in type 1 diabetes mellitus. J Clin Endocrinol Metab 2006; 91(10): 3814-3820.
25. Kastenbauer T, Irsigler P, Sauseng S, Grimm A, Prager R. The prevalence of symptoms of sensorimotor and autonomic neuropathy in Type 1 and Type 2 diabetic subjects. J Diabetes Complications 2004; 18(1): 27-31.
26. Dyck PJ, Litchy WJ, Lehman KA, Hokanson JL, Low PA, O'Brien PC et al. Variables influencing neuropathic endpoints: the Rochester Diabetic Neuropathy Study of Healthy Subjects. Neurology 1995; 45(6): 1115-1121.
27. Tripepi G, Jager KJ, Dekker FW, Zoccali C. Linear and logistic regression analysis. Kidney Int 2008; 73(7): 806-810.
28. Haller MJ, Samyn M, Nichols WW, Brusko T, Wasserfall C, Schwartz RF et al. Radial artery tonometry demonstrates arterial stiffness in children with type 1 diabetes. Diabetes Care 2004; 27(12): 2911-2917.
29. Schram MT, Schalkwijk CG, Bootsma AH, Fuller JH, Chaturvedi N, Stehouwer CD et al. Advanced glycation end products are associated with pulse pressure in type 1 diabetes: the EURODIAB Prospective Complications Study. Hypertension 2005; 46(1): 232-237.
30. O'Rourke MF, Nichols WW. Aortic diameter, aortic stiffness, and wave reflection increase with age and isolated systolic hypertension. Hypertension 2005; 45(4): 652-658.
31. Franklin SS, Gustin W, Wong ND, Larson MG, Weber MA, Kannel WB et al. Hemodynamic patterns of age-related changes in blood pressure. The Framingham Heart Study. Circulation 1997; 96(1): 308-315.
32. Liao D, Arnett DK, Tyroler HA, Riley WA, Chambless LE, SzkloM et al. Arterial stiffness and the development of hypertension. The ARIC study. Hypertension 1999; 34(2): 201-206.
33. Najjar SS, Scuteri A, Shetty V, Wright JG, Muller DC, Fleg JL et al. Pulse wave velocity is an independent predictor of the longitudinal increase in systolic blood pressure and of incident hypertension in the Baltimore Longitudinal Study of Aging. J Am Coll Cardiol 2008; 51(14): 1377-1383.
34. Bahous SA, Stephan A, Barakat W, Blacher J, Asmar R, Safar ME et al. Aortic pulse wave velocity in renal transplant patients. Kidney Int 2004; 66(4): 1486-1492.
35. Toussaint ND, Lau KK, Strauss BJ, Polkinghorne KR, Kerr PG. Associations between vascular calcification, arterial stiffness and bone mineral density in chronic kidney disease. Nephrol Dial Transplant 2008; 23(2): 586-593.
36. Wang MC, Tsai WC, Chen JY, Huang JJ. Stepwise increase in arterial stiffness corresponding with the stages of chronic kidney disease. Am J Kidney Dis 2005; 45(3): 494-501.
37. Matsumae T, Abe Y, Murakami G, Ueda K, Saito T. Effects of glucose metabolism on aortic pulse wave velocity in hemodialysis patients with and without diabetes. Hypertens Res 2008; 31(7): 1365-1372.
38. Paterson AD, Rutledge BN, Cleary PA, Lachin JM, Crow RS. The effect of intensive diabetes treatment on resting heart rate in type 1 diabetes: the Diabetes Control and Complications Trial ? Epidemiology of Diabetes Interventions and Complications study. Diabetes Care 2007; 30(8): 2107-2112.
39. Fraser GE, Luke R, Thompson S, Smith H, Carter S, Sharpe N. Comparison of echocardiographic variables between type I diabetics and normal controls. Am J Cardiol 1995; 75(2): 141-145.
40. Meyer C, Milat F, McGrath BP, Cameron J, Kotsopoulos D, Teede HJ. Vascular dysfunction and autonomic neuropathy in Type 2 diabetes. Diabet Med 2004; 21(7): 746-751.
41. Yokoyama H, Yokota Y, Tada J, Kanno S. Diabetic neuropathy is closely associated with arterial stiffening and thickness in Type 2 diabetes. Diabet Med 2007; 24(12): 1329-1335.
42. Didangelos TP, Arsos GA, Karamitsos DT, Athyros VG, Karatzas ND Left ventricular systolic and diastolic function in normotensive type 1 diabetic patients with or without autonomic neuropathy: a radionuclide ventriculography study. Diabetes Care 2003; 26(7): 1955-1960.
43. Fasching P, Veitl M, Rohac M, Streli C, Schneider B, Waldhausl W et al. Elevated concentrations of circulating adhesion molecules and their association with microvascular complications in insulindependent diabetes mellitus. J Clin Endocrinol Metab 1996; 81(12): 4313-4317.
44. Fuggle SV, Sanderson JB, Gray DW, Richardson A, Morris PJ. Variation in expression of endothelial adhesion molecules in pretransplant and transplanted kidneys-correlation with intragraft events. Transplantation 1993; 55(1): 117-123.
45. Landray MJ, Wheeler DC, Lip GY, Newman DJ, Blann AD, McGlynn FJ et al. Inflammation, endothelial dysfunction, and platelet activation in patients with chronic kidney disease: the chronic renal impairment in Birmingham (CRIB) study. Am J Kidney Dis 2004; 43(2): 244-253.
46. Cottone S, Palermo A, Vaccaro F, Mule G, Guarneri M, Arsena R et al. Inflammation and endothelial activation are linked to renal function in long-term kidney transplantation. Transpl Int 2006; 20(1): 82-87.
47. Malyszko J, Malyszko JS, Pawlak K, Mysliwiec M. The coagulolytic system and endothelial function in cyclosporine-treated kidney allograft recipients. Transplantation 1996; 62(6): 828-830.
48. Gelens MA, Christiaans MH, Hooff JP. Do blood pressure and arterial wall properties change after conversion from cyclosporine to tacrolimus? Transplant Proc 2005; 37(4): 1900-1901.
49. Strozecki P, Adamowicz A, Wlodarczyk Z, Manitius J. The influence of calcineurin inhibitors on pulse wave velocity in renal transplant recipients. Ren Fail 2007; 29(6): 679-684.
50. Darmon P, Dadoun F, Boullu-Ciocca S, Grino M, Alessi MC, Dutour A. Insulin resistance induced by hydrocortisone is increased in patients with abdominal obesity. Am J Physiol Endocrinol Metab 2006; 291(5): E995-E1002.