Oncogenic ras signals through activation of both phosphoinositide 3-kinase and Rac1 to induce c-Jun NH2-terminal kinase-mediated, caspase-independent cell death

Molecular Cancer Research

Volumn 7, Issue 9, 2009, Pages 1534-1542

  Byun, Joo Yun ^a   Kim, Min Jung ^a   Yoon, Chang Hwan ^a   Cha, Hyukjin ^b   Yoon, Gyesoon ^c   Lee, Su Jae ^a  

^a Hanyang University   (South Korea)

^b CHA University   (South Korea)

^c Ajou University School of Medicine   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; CASPASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN P110; PROTEIN P85; RAC1 PROTEIN; RAS PROTEIN; SMALL INTERFERING RNA; STRESS ACTIVATED PROTEIN KINASE;

ANIMAL CELL; ARTICLE; CELL DEATH; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; KNOCKOUT GENE; MOLECULAR INTERACTION; MOLECULAR MECHANICS; MOUSE; NONHUMAN; ONCOGENE RAS; PRIORITY JOURNAL; RAT; RETROVIRUS; SIGNAL TRANSDUCTION; VIRUS EXPRESSION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; ANTHRACENES; CASPASES; CELL DEATH; ENZYME ACTIVATION; FLOW CYTOMETRY; GENETIC VECTORS; HUMANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MICE; NIH 3T3 CELLS; RAC1 GTP-BINDING PROTEIN; RAS PROTEINS; RATS; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; STATISTICS, NONPARAMETRIC;

EID: 70349479251     PISSN: 15417786     EISSN: None     Source Type: Journal    
DOI: 10.1158/1541-7786.MCR-08-0542     Document Type: Article

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