Efficacy of antiretroviral therapy program in children in India: Prognostic factors and survival analysis

Journal of Tropical Pediatrics

Volumn 55, Issue 4, 2009, Pages 225-232

  Rajasekaran, S ^a   Jeyaseelan, L ^b   Ravichandran, N ^a   Gomathi, C ^a   Thara, Francis ^a   Chandrasekar, C ^a  

^a GOVERNMENT GENERAL HOSPITAL   (India)

^b CHRISTIAN MEDICAL COLLEGE   (India)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIRETROVIRUS AGENT; EFAVIRENZ; HEMOGLOBIN; LAMIVUDINE; NEVIRAPINE; STAVUDINE; ZIDOVUDINE;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ADULT; ARTICLE; CD4 LYMPHOCYTE COUNT; CHILD; CONTROLLED STUDY; DRUG EFFICACY; DRUG RESPONSE; FEMALE; HEMOGLOBIN BLOOD LEVEL; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; INDIA; INFECTION RISK; LYMPHOCYTE COUNT; MAJOR CLINICAL STUDY; MALE; MORTALITY; PROBABILITY; PROGNOSIS; RURAL AREA; SENSITIVITY AND SPECIFICITY; SURVIVAL; TERTIARY HEALTH CARE; URBAN AREA;

ADOLESCENT; ANTIRETROVIRAL THERAPY, HIGHLY ACTIVE; CHILD; CHILD, PRESCHOOL; FEMALE; HIV INFECTIONS; HIV-1; HUMANS; INDIA; MALE; PROGNOSIS; PROPORTIONAL HAZARDS MODELS; SOCIOECONOMIC FACTORS; SURVIVAL ANALYSIS; TREATMENT OUTCOME; WEIGHT GAIN;

EID: 70349445090     PISSN: 01426338     EISSN: 14653664     Source Type: Journal    
DOI: 10.1093/tropej/fmm073     Document Type: Article

References (16)

1. WHO World Health Organisation. http://www.who.int/hiv/mediacentre/ 2006_EpiUpdate_en.pdf. (20 December 2006, date last accessed).
2. Tamilnadu State AIDS control Society. The Tamilnadu HIV Sentinel Surveillance Report 2005. Chennai, India. pp. 23.
3. United Nations Acquired Immune Deficiency Syndrome. Global summary of the HIV/AIDS epidemic. December 2005. http://www.unaids.org/Unaids/EN/ Resources/epidemiology/epicore.asp (28 December 2005, date last accessed).
4. Englund JA, Baker CJ, Raskino C, et al. Zidovudine, didanosine, or both as the initial treatment for symptomatic HIV-infected children. N Engl J Med 1997;336:1704-12.
5. Paediatric European Network for Treatment of AIDS. A randomized double-blind trial of the addition of lamivudine or matching placebo to current nucleoside analogue reverse transcriptase inhibitor therapy in HIV-infected children. AIDS 1998;12:F151-60.
6. Kline MW, Van Dyke RB, Lindsey JC, et al. Combination therapy with stavudine (d4T) plus didanosie (ddl) in children with Human Immunodeficiency Virus infection. Pediatrics 1999;103:62-9.
7. Burns DN, Mofenson LM. Pediatric HIV-1 infection. Lancet 1999;354(Suppl 2): S1-6.
8. Reddi A, Leeper SC, Grobler AC, et al. Preliminary outcomes of a paediatric highly active antiretroviral therapy cohort from KwaZulu-Natal, South Africa. BMC Pediatr, 2007;7:13.
9. World Health Organization (WHO). Scaling up antiretroviral therapy in resource-limited settings. Geneva, 2004. http://www.who.int/hiv/pub/ prev_care/en/arvrevision2003en.pdf (1 December 2006, date last accessed).
10. McConnel SM, Byers RH, Frederick T, et al. Trends in antiretroviral therapy use and survival rates for a large cohort of HIV-infected children and adolescents in the United States, 1989-2001. J Acquir Immune Defic Syndr 2005;38:488-94.
11. Gortmaker SL, Hughes M, Cervia J, et al. Effect of combination therapy including protease inhibitors on mortality among children and adolescents infected with HIV-1. N Engl J Med 2001;345:1522-8.
12. Phillips AN, Grabar S, Tassie JM, et al. Use of observational databases to evaluate the effectiveness to evaluate the effectiveness of antiretroviral therapy for HIV infection: Comparison of cohort studies with randomized controlled trials. AIDS 1999;13:2075-82.
13. Buchacz K, Cervia JS, Lindsey JC, et al. Impact of protease inhibitor containing combination antiretroviral therapies on height and weight growth in HIV infected children. Pediatrics 2001;108:e72.
14. Mueller BU, Sleasman J, Nelson RP, Jr, et al. A phase I/II study of the protease inhibitor indinavir in children with HIV infection. Pediatrics 1998;102:101-9.
15. Nachman SA, Stanley K, Yogev R, et al. Nucleoside analogs plus retinovir in stable antiretroviral therapy experienced HIV infected children: A randomized controlled trial. JAMA, 2000;283:492-8.
16. Italian Register for HIV infection in children. Rapid disease progression in HIV-1 perinatally infected children born to mothers receiving Zidovudine monotherapy during pregnancy. AIDS 1999;13:927-33.