Spontaneous thymic lymphomas in the non-obese diabetic/Shi-scid, IL-2Rγnull mouse

Laboratory Animals

Volumn 43, Issue 4, 2009, Pages 402-404

  Kato, Chie ^a,b   Fujii, Etsuko ^a,b   Chen, Yu Jau ^a   Endaya, Berwini B ^a   Matsubara, Koichi ^a   Suzuki, Masami ^b   Ohnishi, Yasuyuki ^c   Tamaoki, Norikazu ^c  

^a PharmaLogicals Research Pte Ltd   (Singapore)

^b CHUGAI PHARMACEUTICAL CO LTD   (Japan)

^c CENTRAL INSTITUTE FOR EXPERIMENTAL ANIMALS   (Japan)

Author keywords

IL 2R null; Immunodeficient mouse; NOD Shi scid; NOG mouse; Spontaneous thymic lymphoma; T cell

Indexed keywords

INTERLEUKIN 2 RECEPTOR GAMMA; THY 1 ANTIGEN;

ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; FEMALE; HEART; HISTOLOGY; IMMUNOHISTOCHEMISTRY; INCIDENCE; KIDNEY; LIVER; LUNG; LYMPHOBLAST; MALE; MITOSIS; MOUSE; NONHUMAN; NONOBESE DIABETIC MOUSE; SPLEEN; SPONTANEOUS THYMIC LYMPHOMA; THORAX; THYMUS LYMPHOMA; TUMOR ENGRAFTMENT; TUMOR LOCALIZATION; TUMOR VOLUME;

ANIMALS; FEMALE; HUMANS; JAPAN; LYMPHOMA; MALE; MICE; MICE, INBRED NOD; MICE, KNOCKOUT; MICE, SCID; THYMUS NEOPLASMS; TRANSPLANTATION CHIMERA; TRANSPLANTATION, HETEROLOGOUS;

MUS;

EID: 70349444922     PISSN: 00236772     EISSN: None     Source Type: Journal    
DOI: 10.1258/la.2009.009012     Document Type: Article

References (10)

1. Ito M, Hiramatsu H, Kobayashi K, et al. NOD/SCID/gamma(c)(null) mouse: an excellent recipient mouse model for engraftment of human cells. Blood 2002;100:3175-3182 (Pubitemid 35217065)
2. null mouse. Pathol Int 2008;58:559-567
3. Custer RP, Bosma GC, Bosma MJ. Severe combined immunodeficiency (SCID) in the mouse. Pathology, reconstitution, neoplasms. Am J Pathol 1985;120:464-477 (Pubitemid 15250108)
4. Prochazka M, Gaskins HR, Shultz LD, Leiter EH. The nonobese diabetic scid mouse: model for spontaneous thymomagenesis associated with immunodeficiency. Proc Natl Acad Sci USA 1992;89:3290-3304
5. Shultz LD, Lyons BL, Burzenski LM, et al. Human lymphoid and myeloid cell development in NOD/LtSz-scid IL2R gamma null mice engrafted with mobilized human hemopoietic stem cells. J Immunol 2005;174:6477-6489
6. Sato Y, Mukai K, Watanabe S, Goto M, Shimosato Y. The AMeX method. A simplified technique of tissue processing and paraffin embedding with improved preservation of antigens for immunostaining. Am J Pathol 1986;125:431-435 (Pubitemid 17208827)
7. Suzuki M, Katsuyama K, Adachi K, et al. Combination of fixation using PLP fixative and embedding in paraffin by the AMeX method is useful for histochemical studies in assessment of immunotoxicity. J Toxicol Sci 2002;27:165-172 (Pubitemid 34988293)
8. Gunter KC, Malek TR, Shevach EM. T cell-activating properties of an anti-Thy-1 monoclonal antibody. Possible analogy to OKT3/Leu-4. J Exp Med 1984;159:716-730
9. Morse HC 3rd, Anver MR, Fredrickson TN, et al. Bethesda proposals for classification of lymphoid neoplasms in mice. Blood 2002;100:246-258
10. null NOD-scid mice. An improved host for adoptive transfer of autoimmune diabetes and growth of human lymphohematopoietic cells. Diabetes 1995;44:1392-1398