-
1
-
-
0035425811
-
HFE gene and hereditary hemochromatosis: a HuGE review. Human Genome Epidemiology
-
Hanson E.H., Imperatore G., and Burke W. HFE gene and hereditary hemochromatosis: a HuGE review. Human Genome Epidemiology. Am J Epidemiol 154 (2001) 193-206
-
(2001)
Am J Epidemiol
, vol.154
, pp. 193-206
-
-
Hanson, E.H.1
Imperatore, G.2
Burke, W.3
-
2
-
-
0032401683
-
Hemochromatosis-associated mortality in the United States from 1979 to 1992: an analysis of multiple-cause mortality data
-
Yang Q., McDonnell S.M., Khoury M.J., et al. Hemochromatosis-associated mortality in the United States from 1979 to 1992: an analysis of multiple-cause mortality data. Ann Intern Med 129 (1998) 946-953
-
(1998)
Ann Intern Med
, vol.129
, pp. 946-953
-
-
Yang, Q.1
McDonnell, S.M.2
Khoury, M.J.3
-
4
-
-
0022368621
-
Survival and causes of death in cirrhotic and in noncirrhotic patients with primary hemochromatosis
-
Niederau C., Fischer R., Sonnenberg A., et al. Survival and causes of death in cirrhotic and in noncirrhotic patients with primary hemochromatosis. N Engl J Med 313 (1985) 1256-1262
-
(1985)
N Engl J Med
, vol.313
, pp. 1256-1262
-
-
Niederau, C.1
Fischer, R.2
Sonnenberg, A.3
-
5
-
-
0035678345
-
Clinically overt hereditary hemochromatosis in Denmark 1948-1985: epidemiology, factors of significance for long-term survival, and causes of death in 179 patients
-
Milman N., Pedersen P., Steig T., et al. Clinically overt hereditary hemochromatosis in Denmark 1948-1985: epidemiology, factors of significance for long-term survival, and causes of death in 179 patients. Ann Hematol 80 (2001) 737-744
-
(2001)
Ann Hematol
, vol.80
, pp. 737-744
-
-
Milman, N.1
Pedersen, P.2
Steig, T.3
-
6
-
-
0031835884
-
HFE mutations in patients with hereditary haemochromatosis in Sweden
-
Cardoso E.M., Stal P., Hagen K., et al. HFE mutations in patients with hereditary haemochromatosis in Sweden. J Intern Med 243 (1998) 203-208
-
(1998)
J Intern Med
, vol.243
, pp. 203-208
-
-
Cardoso, E.M.1
Stal, P.2
Hagen, K.3
-
7
-
-
0031419386
-
A candidate gene for hemochromatosis: frequency of the C282Y and H63D mutations
-
Jouanolle A.M., Fergelot P., Gandon G., et al. A candidate gene for hemochromatosis: frequency of the C282Y and H63D mutations. Hum Genet 100 (1997) 544-547
-
(1997)
Hum Genet
, vol.100
, pp. 544-547
-
-
Jouanolle, A.M.1
Fergelot, P.2
Gandon, G.3
-
8
-
-
0031729616
-
Prevalence of the C282Y and H63D mutations in the HFE gene in patients with hereditary haemochromatosis and in control subjects from Northern Germany
-
Nielsen P., Carpinteiro S., Fischer R., et al. Prevalence of the C282Y and H63D mutations in the HFE gene in patients with hereditary haemochromatosis and in control subjects from Northern Germany. Br J Haematol 103 (1998) 842-845
-
(1998)
Br J Haematol
, vol.103
, pp. 842-845
-
-
Nielsen, P.1
Carpinteiro, S.2
Fischer, R.3
-
9
-
-
0033606807
-
Iron, atherosclerosis, and ischemic heart disease
-
de Valk B., and Marx J.J. Iron, atherosclerosis, and ischemic heart disease. Arch Intern Med 159 (1999) 1542-1548
-
(1999)
Arch Intern Med
, vol.159
, pp. 1542-1548
-
-
de Valk, B.1
Marx, J.J.2
-
10
-
-
0026635456
-
Iron and oxygen radicals in brain
-
Gutteridge J.M. Iron and oxygen radicals in brain. Ann Neurol 32 Suppl (1992) S16-S21
-
(1992)
Ann Neurol
, vol.32
, Issue.SUPPL
-
-
Gutteridge, J.M.1
-
11
-
-
9444258632
-
Role of oxygen radicals in DNA damage and cancer incidence
-
Valko M., Izakovic M., Mazur M., et al. Role of oxygen radicals in DNA damage and cancer incidence. Mol Cell Biochem 266 (2004) 37-56
-
(2004)
Mol Cell Biochem
, vol.266
, pp. 37-56
-
-
Valko, M.1
Izakovic, M.2
Mazur, M.3
-
12
-
-
1642566560
-
Hemochromatosis and the enigma of misplaced iron: implications for infectious disease and survival
-
Moalem S., Weinberg E.D., and Percy M.E. Hemochromatosis and the enigma of misplaced iron: implications for infectious disease and survival. Biometals 17 (2004) 135-139
-
(2004)
Biometals
, vol.17
, pp. 135-139
-
-
Moalem, S.1
Weinberg, E.D.2
Percy, M.E.3
-
13
-
-
20244372858
-
Hemochromatosis and iron-overload screening in a racially diverse population
-
Adams P.C., Reboussin D.M., Barton J.C., et al. Hemochromatosis and iron-overload screening in a racially diverse population. N Engl J Med 352 (2005) 1769-1778
-
(2005)
N Engl J Med
, vol.352
, pp. 1769-1778
-
-
Adams, P.C.1
Reboussin, D.M.2
Barton, J.C.3
-
14
-
-
0029827481
-
Clinical and biochemical abnormalities in people heterozygous for hemochromatosis
-
Bulaj Z.J., Griffen L.M., Jorde L.B., et al. Clinical and biochemical abnormalities in people heterozygous for hemochromatosis. N Engl J Med 335 (1996) 1799-1805
-
(1996)
N Engl J Med
, vol.335
, pp. 1799-1805
-
-
Bulaj, Z.J.1
Griffen, L.M.2
Jorde, L.B.3
-
15
-
-
0031793132
-
The significance of haemochromatosis gene mutations in the general population: implications for screening
-
Burt M.J., George P.M., Upton J.D., et al. The significance of haemochromatosis gene mutations in the general population: implications for screening. Gut 43 (1998) 830-836
-
(1998)
Gut
, vol.43
, pp. 830-836
-
-
Burt, M.J.1
George, P.M.2
Upton, J.D.3
-
16
-
-
0346873990
-
Haemochromatosis-associated HFE genotypes in English blood donors: age-related frequency and biochemical expression
-
Chambers V., Sutherland L., Palmer K., et al. Haemochromatosis-associated HFE genotypes in English blood donors: age-related frequency and biochemical expression. J Hepatol 39 (2003) 925-931
-
(2003)
J Hepatol
, vol.39
, pp. 925-931
-
-
Chambers, V.1
Sutherland, L.2
Palmer, K.3
-
17
-
-
0034061677
-
Non-transferrin-bound iron is present in serum of hereditary haemochromatosis heterozygotes
-
de Valk B., Addicks M.A., Gosriwatana I., et al. Non-transferrin-bound iron is present in serum of hereditary haemochromatosis heterozygotes. Eur J Clin Invest 30 (2000) 248-251
-
(2000)
Eur J Clin Invest
, vol.30
, pp. 248-251
-
-
de Valk, B.1
Addicks, M.A.2
Gosriwatana, I.3
-
18
-
-
0033664075
-
Biochemical expression of heterozygous hereditary hemochromatosis
-
de Valk B., Witlox R.S., van der Schouw Y.T., et al. Biochemical expression of heterozygous hereditary hemochromatosis. Eur J Intern Med 11 (2000) 317-321
-
(2000)
Eur J Intern Med
, vol.11
, pp. 317-321
-
-
de Valk, B.1
Witlox, R.S.2
van der Schouw, Y.T.3
-
19
-
-
0034883430
-
HFE mutations, iron deficiency and overload in 10,500 blood donors
-
Jackson H.A., Carter K., Darke C., et al. HFE mutations, iron deficiency and overload in 10,500 blood donors. Br J Haematol 114 (2001) 474-484
-
(2001)
Br J Haematol
, vol.114
, pp. 474-484
-
-
Jackson, H.A.1
Carter, K.2
Darke, C.3
-
20
-
-
0031839335
-
The effect of HFE mutations on serum ferritin and transferrin saturation in the Jersey population
-
Merryweather-Clarke A.T., Worwood M., Parkinson L., et al. The effect of HFE mutations on serum ferritin and transferrin saturation in the Jersey population. Br J Haematol 101 (1998) 369-373
-
(1998)
Br J Haematol
, vol.101
, pp. 369-373
-
-
Merryweather-Clarke, A.T.1
Worwood, M.2
Parkinson, L.3
-
21
-
-
0037366790
-
A population-based study of the effect of the HFE C282Y and H63D mutations on iron metabolism
-
Njajou O.T., Houwing-Duistermaat J.J., Osborne R.H., et al. A population-based study of the effect of the HFE C282Y and H63D mutations on iron metabolism. Eur J Hum Genet 11 (2003) 225-231
-
(2003)
Eur J Hum Genet
, vol.11
, pp. 225-231
-
-
Njajou, O.T.1
Houwing-Duistermaat, J.J.2
Osborne, R.H.3
-
22
-
-
0002878060
-
Prevalence and penetrance of HFE mutations in 4865 unselected primary care patients
-
Phatak P.D., Ryan D.H., Cappuccio J., et al. Prevalence and penetrance of HFE mutations in 4865 unselected primary care patients. Blood Cells Mol Dis 29 (2002) 41-47
-
(2002)
Blood Cells Mol Dis
, vol.29
, pp. 41-47
-
-
Phatak, P.D.1
Ryan, D.H.2
Cappuccio, J.3
-
24
-
-
33645121766
-
Iron loading and morbidity among relatives of HFE C282Y homozygotes identified either by population genetic testing or presenting as patients
-
McCune C.A., Ravine D., Carter K., et al. Iron loading and morbidity among relatives of HFE C282Y homozygotes identified either by population genetic testing or presenting as patients. Gut 55 (2006) 554-562
-
(2006)
Gut
, vol.55
, pp. 554-562
-
-
McCune, C.A.1
Ravine, D.2
Carter, K.3
-
25
-
-
0036708279
-
Concordance of iron indices in homozygote and heterozygote sibling pairs in hemochromatosis families: implications for family screening
-
Whiting P.W., Fletcher L.M., Dixon J.K., et al. Concordance of iron indices in homozygote and heterozygote sibling pairs in hemochromatosis families: implications for family screening. J Hepatol 37 (2002) 309-314
-
(2002)
J Hepatol
, vol.37
, pp. 309-314
-
-
Whiting, P.W.1
Fletcher, L.M.2
Dixon, J.K.3
-
26
-
-
38049011311
-
Morbidity and mortality in first-degree relatives of C282Y homozygous probands with clinically detected haemochromatosis compared with the general population: the HEmochromatosis FAmily Study (HEFAS)
-
Jacobs E.M., Hendriks J.C., Marx J.J., et al. Morbidity and mortality in first-degree relatives of C282Y homozygous probands with clinically detected haemochromatosis compared with the general population: the HEmochromatosis FAmily Study (HEFAS). Neth J Med 65 (2007) 425-433
-
(2007)
Neth J Med
, vol.65
, pp. 425-433
-
-
Jacobs, E.M.1
Hendriks, J.C.2
Marx, J.J.3
-
27
-
-
56949087432
-
Severity of iron overload of proband determines serum ferritin levels in families with HFE-related hemochromatosis: the HEmochromatosis FAmily Study
-
Jacobs E.M., Hendriks J.C., van Deursen C.T., et al. Severity of iron overload of proband determines serum ferritin levels in families with HFE-related hemochromatosis: the HEmochromatosis FAmily Study. J Hepatol 50 (2009) 174-183
-
(2009)
J Hepatol
, vol.50
, pp. 174-183
-
-
Jacobs, E.M.1
Hendriks, J.C.2
van Deursen, C.T.3
-
28
-
-
26244440542
-
Phenotype variation in C282Y homozygotes for the hemochromatosis gene
-
Lazarescu A., Snively B.M., and Adams P.C. Phenotype variation in C282Y homozygotes for the hemochromatosis gene. Clin Gastroenterol Hepatol 3 (2005) 1043-1046
-
(2005)
Clin Gastroenterol Hepatol
, vol.3
, pp. 1043-1046
-
-
Lazarescu, A.1
Snively, B.M.2
Adams, P.C.3
-
29
-
-
0029913626
-
Long-term survival in patients with hereditary hemochromatosis
-
Niederau C., Fischer R., Purschel A., et al. Long-term survival in patients with hereditary hemochromatosis. Gastroenterology 110 (1996) 1107-1119
-
(1996)
Gastroenterology
, vol.110
, pp. 1107-1119
-
-
Niederau, C.1
Fischer, R.2
Purschel, A.3
-
30
-
-
0035851274
-
Association of mutations in the hemochromatosis gene with shorter life expectancy
-
Bathum L., Christiansen L., Nybo H., et al. Association of mutations in the hemochromatosis gene with shorter life expectancy. Arch Intern Med 161 (2001) 2441-2444
-
(2001)
Arch Intern Med
, vol.161
, pp. 2441-2444
-
-
Bathum, L.1
Christiansen, L.2
Nybo, H.3
-
32
-
-
0036428690
-
No increase in mortality and morbidity among carriers of the C282Y mutation of the hereditary haemochromatosis gene in the oldest old: the Leiden 85-plus study
-
Van Aken M.O., De Craen A.J., Gussekloo J., et al. No increase in mortality and morbidity among carriers of the C282Y mutation of the hereditary haemochromatosis gene in the oldest old: the Leiden 85-plus study. Eur J Clin Invest 32 (2002) 750-754
-
(2002)
Eur J Clin Invest
, vol.32
, pp. 750-754
-
-
Van Aken, M.O.1
De Craen, A.J.2
Gussekloo, J.3
-
33
-
-
0037132786
-
Penetrance of 845G-> A (C282Y) HFE hereditary haemochromatosis mutation in the USA
-
Beutler E., Felitti V.J., Koziol J.A., et al. Penetrance of 845G-> A (C282Y) HFE hereditary haemochromatosis mutation in the USA. Lancet 359 (2002) 211-218
-
(2002)
Lancet
, vol.359
, pp. 211-218
-
-
Beutler, E.1
Felitti, V.J.2
Koziol, J.A.3
-
34
-
-
0019248320
-
The person-number systems of Sweden, Norway, Denmark, and Israel
-
Lunde A.S., Lundeborg S., Lettenstrom G.S., et al. The person-number systems of Sweden, Norway, Denmark, and Israel. Vital Health Stat 2 84 (1980) 1-59
-
(1980)
Vital Health Stat 2
, vol.84
, pp. 1-59
-
-
Lunde, A.S.1
Lundeborg, S.2
Lettenstrom, G.S.3
-
35
-
-
10744232491
-
Cancer risk in patients with hereditary hemochromatosis and in their first-degree relatives
-
Elmberg M., Hultcrantz R., Ekbom A., et al. Cancer risk in patients with hereditary hemochromatosis and in their first-degree relatives. Gastroenterology 125 (2003) 1733-1741
-
(2003)
Gastroenterology
, vol.125
, pp. 1733-1741
-
-
Elmberg, M.1
Hultcrantz, R.2
Ekbom, A.3
-
36
-
-
1842579593
-
Hemochromatosis mutations in the general population: iron overload progression rate
-
Andersen R.V., Tybjaerg-Hansen A., Appleyard M., et al. Hemochromatosis mutations in the general population: iron overload progression rate. Blood 103 (2004) 2914-2919
-
(2004)
Blood
, vol.103
, pp. 2914-2919
-
-
Andersen, R.V.1
Tybjaerg-Hansen, A.2
Appleyard, M.3
-
37
-
-
57249103568
-
The natural history of serum iron indices for HFE C282Y homozygosity associated with hereditary hemochromatosis
-
Gurrin L.C., Osborne N.J., Constantine C.C., et al. The natural history of serum iron indices for HFE C282Y homozygosity associated with hereditary hemochromatosis. Gastroenterology 135 (2008) 1945-1952
-
(2008)
Gastroenterology
, vol.135
, pp. 1945-1952
-
-
Gurrin, L.C.1
Osborne, N.J.2
Constantine, C.C.3
-
38
-
-
0032401683
-
Hemochromatosis-associated mortality in the United States from 1979 to 1992: an analysis of multiple-cause mortality data
-
Yang Q., McDonnell S.M., Khoury M.J., et al. Hemochromatosis-associated mortality in the United States from 1979 to 1992: an analysis of multiple-cause mortality data. Ann Intern Med 129 (1998) 946-953
-
(1998)
Ann Intern Med
, vol.129
, pp. 946-953
-
-
Yang, Q.1
McDonnell, S.M.2
Khoury, M.J.3
-
39
-
-
0033578246
-
Haemochromatosis gene C282Y homozygotes in an elderly male population
-
Willis G., Wimperis J.Z., Smith K.C., et al. Haemochromatosis gene C282Y homozygotes in an elderly male population. Lancet 354 (1999) 221-222
-
(1999)
Lancet
, vol.354
, pp. 221-222
-
-
Willis, G.1
Wimperis, J.Z.2
Smith, K.C.3
-
40
-
-
0021910539
-
Low-molecular-weight iron complexes and oxygen radical reactions in idiopathic haemochromatosis
-
Gutteridge J.M., Rowley D.A., Griffiths E., et al. Low-molecular-weight iron complexes and oxygen radical reactions in idiopathic haemochromatosis. Clin Sci (Lond) 68 (1985) 463-467
-
(1985)
Clin Sci (Lond)
, vol.68
, pp. 463-467
-
-
Gutteridge, J.M.1
Rowley, D.A.2
Griffiths, E.3
-
41
-
-
0023901798
-
Prevalence of hemochromatosis among 11,065 presumably healthy blood donors
-
Edwards C.Q., Griffen L.M., Goldgar D., et al. Prevalence of hemochromatosis among 11,065 presumably healthy blood donors. N Engl J Med 318 (1988) 1355-1362
-
(1988)
N Engl J Med
, vol.318
, pp. 1355-1362
-
-
Edwards, C.Q.1
Griffen, L.M.2
Goldgar, D.3
-
42
-
-
2442695048
-
No age-related decrease in frequency of heterozygotes for the HFE C282Y haemochromatosis mutation
-
Waalen J., and Beutler E. No age-related decrease in frequency of heterozygotes for the HFE C282Y haemochromatosis mutation. J Hepatol 40 (2004) 1044-1045
-
(2004)
J Hepatol
, vol.40
, pp. 1044-1045
-
-
Waalen, J.1
Beutler, E.2
-
43
-
-
46349085839
-
HFE C282Y homozygotes have reduced low-density lipoprotein cholesterol: the Atherosclerosis Risk in Communities (ARIC) Study
-
Pankow J.S., Boerwinkle E., Adams P.C., et al. HFE C282Y homozygotes have reduced low-density lipoprotein cholesterol: the Atherosclerosis Risk in Communities (ARIC) Study. Transl Res 152 (2008) 3-10
-
(2008)
Transl Res
, vol.152
, pp. 3-10
-
-
Pankow, J.S.1
Boerwinkle, E.2
Adams, P.C.3
-
44
-
-
0344806959
-
-
Centre for Epidemiology NBoHaW, National Board of Health and Welfare, Stockholm, Sweden
-
Centre for Epidemiology NBoHaW. The Swedish Inpatient Register 1987-1995 (1997), National Board of Health and Welfare, Stockholm, Sweden
-
(1997)
The Swedish Inpatient Register 1987-1995
-
-
|