Cleaning verification: Method development and validation using ion mobility spectrometry

Pharmaceutical Technology

Volumn 33, Issue 7, 2009, Pages 60-63

  Galella, Elizabeth ^a   Jennings, Scott ^a   Srikoti, Madhavi ^a   Bonasso, Elizabeth ^a  

^a BRISTOL MYERS SQUIBB   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANALYTICAL TOOL; CLEANING VERIFICATION; HPLC ANALYSIS; ION MOBILITY SPECTROMETRY; METHOD DEVELOPMENT; PHARMACEUTICAL EQUIPMENT; STANDARD DEVIATION;

CLEAN ROOMS; CLEANING; SPECTROMETRY;

HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;

ARTICLE; CLEANING; EQUIPMENT; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ION MOBILITY SPECTROMETRY; VALIDATION PROCESS;

EID: 70349424890     PISSN: 15432521     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (6)

1. G. Walia et al., "Using Ion Mobility Spectrometry for Cleaning Verification in Pharmaceutical Manufacturing," Pharm. Technol. 27 (4), 72-78 (2002).
2. G. Walia et al., "Implementing Ion Mobility Spectrometry as a Cleaning Verification Method," Pharm. Technol. 27 (3), 22-25 (2002).
3. D. Brand, X. Li, and T. Wortley, "Ion Trap Mobility Spectrometry: Reducing Downtime in Cleaning Validation and Verification," GE Sensing, www.gesensing.com/toolsupport/whitepaper.htm, accessed June 16,2009.
4. D. Brand et al., "Direct Swabbing and Surface Recovery with Ion Trap Mobility Spectrometry," GE Sensing, www.gesensing.com/products/resources/ datasheets/GEsensing-whitepaperfinal.pdf, accessed June 2,2009.
5. R. DeBono, "Ion Mobility Spectrometry: A Fast, Sensitive, and Robust HPLC Alternative," AppL in Chrom. March, 20-23 (2002), http://trace.smithsdetection.com/Documents/LifeSciences/LE203sBarringer.pdf.
6. G.A. Eiceman, "Advances in Ion Mobility Spectrometry," Crit. Rev. Anal. Chem. 22 (1,2), 471-490 (1990).