Evaluation of proteinuria and GFR to diagnose and classify kidney disease: Systematic review and proof of concept

European Journal of Internal Medicine

Volumn 20, Issue 6, 2009, Pages 556-561

  Regeniter, Axel ^a   Freidank, Heike ^a   Dickenmann, Michael ^a   Boesken, Wolf H ^b   Siede, Werner H ^c  

^a UNIVERSITY HOSPITAL BASEL   (Switzerland)

^b Klinikum Lippe Lemgo ^*  (Germany)

^c KLINIKUM LIPPE DETMOLD   (Germany)

Author keywords

Glomerular filtration rate (GFR); Glomerular proteinuria; Knowledge based system; Proteinuria differentiation; Tubular proteinuria

Indexed keywords

ALPHA 1 MICROGLOBULIN; IMMUNOGLOBULIN G; SERUM ALBUMIN; TRANSFERRIN;

DIABETES MELLITUS; DIABETIC NEPHROPATHY; GLOMERULUS FILTRATION RATE; HUMAN; KIDNEY DISEASE; KIDNEY FUNCTION; PATHOGENESIS; PROLIFERATIVE GLOMERULONEPHRITIS; PROTEIN URINE LEVEL; PROTEINURIA; REVIEW; URINALYSIS;

CHRONIC DISEASE; GLOMERULAR FILTRATION RATE; HUMANS; KIDNEY DISEASES; PROTEINURIA;

EID: 70349416601     PISSN: 09536205     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejim.2009.03.006     Document Type: Review

References (25)

1. John R., Webb M., Young A., and Stevens P.E. Unreferred chronic kidney disease: a longitudinal study. Am J Kidney Dis 43 (2004) 825-835
2. Chadban S.J., Briganti E.M., Kerr P.G., Dunstan D.W., Welborn T.A., Zimmet P.Z., et al. Prevalence of kidney damage in Australian adults: the AusDiab kidney study. J Am Soc Nephrol 14 (2003) S131-S138
3. Cameron J.S., and Blandford G. The simple assessment of selectivity in heavy proteinuria. Lancet 2 (1966) 242-247
4. D'Amico G., and Bazzi C. Pathophysiology of proteinuria. Kidney Int 63 (2003) 809-825
5. Deveugele M., Derese A., van d.B., Bensing J., and De M.J. Consultation length in general practice: cross sectional study in six European countries. BMJ 325 (2002) 472
6. Regeniter A., Steiger J.U., Scholer A., Huber P.R., and Siede W.H. Windows to the ward: graphically oriented report forms. Presentation of complex, interrelated laboratory data for electrophoresis/immunofixation, cerebrospinal fluid, and urinary protein profiles. Clin Chem 49 (2003) 41-50
7. N.K. Foundation, 2002. Kidney Disease Outcome Quality Initiative (K/DOQI) Advisory Board: clinical practice guidelines for chronic kidney disease: evaluation, classification, and stratification. Kidney Disease Outcome Quality Initiative. Guideline 4. Estimation of GFR / Guidel. Am. J. Kidney Dis. 39.
8. Verhave J.C., Gansevoort R.T., Hillege H.L., De Z.D., Curhan G.C., and de Jong P.E. Drawbacks of the use of indirect estimates of renal function to evaluate the effect of risk factors on renal function. J Am Soc Nephrol 15 (2004) 1316-1322
9. Giles P.D., and Fitzmaurice D.A. Formula estimation of glomerular filtration rate: have we gone wrong?. BMJ 334 (2007) 1198-1200
10. Grubb A., Nyman U., Bjork J., Lindstrom V., Rippe B., Sterner G., et al. Simple cystatin C-based prediction equations for glomerular filtration rate compared with the modification of diet in renal disease prediction equation for adults and the Schwartz and the Counahan-Barratt prediction equations for children. Clin Chem 51 (2005) 1420-1431
11. Knight E.L., Verhave J.C., Spiegelman D., et al. Factors influencing serum cystatin C levels other than renal function and the impact on renal function measurement. Kidney Int 65 (2004) 1416-1421
12. Vanholder R. Chronic kidney disease in adults - UK guidelines for identification, management and referral. Nephrol Dial Transplant 21 (2006) 1776-1777
13. Boesken W.H. Diagnostic significance of SDS-PAA-electrophoresis of urinary proteins: different forms of proteinuria and their correlation to renal diseases. Curr Probl Clin Biochem (1979) 235-248
14. Stierle H.E., Oser B., and Boesken W.H. Improved classification of proteinuria by semiautomated ultrathin SDS polyacrylamide gel electrophoresis. Clin Nephrol 33 (1990) 168-173
15. Bazzi C., Petrini C., Rizza V., Arrigo G., Beltrame A., Pisano L., et al. Urinary excretion of IgG and alpha(1)-microglobulin predicts clinical course better than extent of proteinuria in membranous nephropathy. Am J Kidney Dis 38 (2001) 240-248
16. Guder W.G., and Hofmann W. Differentiation of proteinuria and haematuria by single protein analysis in urine. Clin Biochem 26 (1993) 277-282
17. Regeniter A., Siede W.H., Scholer A., Huber P., Frischmuth N., and Steiger J.U. Interpreting complex urinary patterns with MDI LABLINK: a statistical evaluation. Clin Chim Acta 297 (2000) 261-273
18. Boege F., Koehler B., and Liebermann F. Identification and quantification of Bence-Jones proteinuria by automated nephelometric screening. J Clin Chem Clin Biochem 28 (1990) 37-42
19. Ottiger C., Savoca R., Yurtsever H., and Huber A.R. Increased sensitivity in detecting renal impairments by quantitative measurement of marker protein excretion compared to detection of pathological particles in urine sediment analysis. Clin Chem Lab Med 44 (2006) 1347-1354
20. Shiffrin R.M., and Nosofsky R.M. Seven plus or minus two: a commentary on capacity limitations. Psychol Rev 101 (1994) 357-361
21. Verheij R., Hoeke J.O., Bonke B., van Strik R., and Gelsema E.S. Evaluation of techniques for the presentation of laboratory data. I: Time needed for interpretation. Methods Inf Med 36 (1997) 11-16
22. Deegens J.K., and Wetzels J.F. Fractional excretion of high- and low-molecular weight proteins and outcome in primary focal segmental glomerulosclerosis. Clin Nephrol 68 (2007) 201-208
23. Heeringa S.F., Branten A.J.W., Deegens J.K.J., Steenbergen E., and Wetzels J.F.M. Focal segmental glomerulosclerosis is not a sufficient predictor of renal outcome in patients with membranous nephropathy. Nephrol Dial Transplant 22 (2007) 2201-2207
24. Becker A., and Boesken W.H. Differentialdiagnose renaler Erkrankungen mit der Urinprotein-Elektrophorese (SDS-PAGE). Differential diagnosis of renal diseases by urinary protein electrophoresis (SDS-PAGE). J Lab Med 29 (2005) 317-324
25. Barbosa de Deus R., de Paulo Castro Teixeira V., and Mastroianni Kirsztajn G. Relative contribution of morphometric and functional indicators of tubulointerstitial lesion to glomerular diseases prognosis. Nephron Clin Pract 110 (2008) c164-c171