Mechanism of Hg-C protonolysis in the organomercurial lyase MerB

Journal of the American Chemical Society

Volumn 131, Issue 37, 2009, Pages 13278-13285

  Parks, Jerry M ^a   Guo, Hong ^a,b   Momany, Cory ^c   Liang, Liyuan ^d   Miller, Susan M ^e   Summers, Anne O ^c   Smith, Jeremy C ^a,b  

^a OAK RIDGE NATIONAL LABORATORY   (United States)

^b UNIVERSITY OF TENNESSEE   (United States)

^c UNIVERSITY OF GEORGIA   (United States)

^d OAK RIDGE NATIONAL LABORATORY   (United States)

^e UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION BARRIERS; ACTIVATION FREE ENERGY; ACTIVE SITE; ATOMIC CHARGE; CYSTEINE RESIDUES; DEMETHYLATION; ELECTRON DENSITIES; ENZYMATIC REACTION; HYBRID DENSITY FUNCTIONAL THEORY; HYDROCARBON PRODUCT; KEY REACTIONS; LEAVING GROUPS; MERCURY CYCLING; METHYL MERCURY; NATURAL POPULATION ANALYSIS; ORGANOMERCURIALS; PRODUCT COMPLEX; PROTONATES; PROTONOLYSIS; PROTONOLYSIS REACTION; RATE LIMITING; REACTION MECHANISM; STATIONARY POINTS; THIOLATES; TRANSITION STATE; TRANSITION STATE STRUCTURE; TWO-STEP MECHANISMS; X RAY CRYSTAL STRUCTURES;

ACTIVATION ANALYSIS; ACTIVATION ENERGY; COORDINATION REACTIONS; CRYSTAL ATOMIC STRUCTURE; DENSITY FUNCTIONAL THEORY; HYDROCARBONS; MERCURY COMPOUNDS; PROTONS; REACTION RATES; SUBSTRATES;

MERCURY (METAL);

CARBON; CYSTEINE; HYDROCARBON; MERCURY; METHYLMERCURY; ORGANOMERCURY COMPOUND; PROTON;

ARTICLE; CATALYSIS; CHEMICAL REACTION; CHEMICAL STRUCTURE; CRYSTAL STRUCTURE; DEMETHYLATION; DENSITY FUNCTIONAL THEORY; ENZYME MECHANISM; HYBRID; LYSIS; PROTON TRANSPORT; REACTION ANALYSIS; X RAY CRYSTALLOGRAPHY;

BIOCATALYSIS; CARBON; CATALYTIC DOMAIN; LYASES; MERCURY; MODELS, MOLECULAR; QUANTUM THEORY; WATER;

EID: 70349400866     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja9016123     Document Type: Article

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