Myostatin (GDF8) single nucleotide polymorphisms in Nellore cattle

Genetics and Molecular Research

Volumn 8, Issue 3, 2009, Pages 822-830

  Grisolia, A B ^a,b   D'Angelo, G T ^a   Porto Neto, L R ^a   Siqueira, F ^c   Garcia, J F ^a  

^a SÃO PAULO STATE UNIVERSITY UNESP   (Brazil)

^b UNIVERSIDADE FEDERAL DA GRANDE DOURADOS   (Brazil)

^c EMBRAPA CERRADOS   (Brazil)

Author keywords

Animal breeding; DNA sequencing; Double muscling; Meat production; Single nucleotide polymorphisms

Indexed keywords

DNA; MYOSTATIN; TAURINE;

ALLELE; ARTICLE; ARTIFICIAL SELECTION; BREED DIFFERENCE; CATTLE; CONTROLLED STUDY; DNA SEQUENCE; EXON; GENE AMPLIFICATION; GENE MUTATION; GENE SEQUENCE; GENETIC HETEROGENEITY; INTRON; MEAT INDUSTRY; MUTATION RATE; NONHUMAN; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; SINGLE NUCLEOTIDE POLYMORPHISM; UNTRANSLATED REGION;

ANIMALS; BASE PAIRING; BASE SEQUENCE; CATTLE; EXONS; INTRONS; MOLECULAR SEQUENCE DATA; MYOSTATIN; POLYMORPHISM, SINGLE NUCLEOTIDE; SEQUENCE ALIGNMENT; UNTRANSLATED REGIONS;

ANIMALIA; BOS; BOVINAE;

EID: 70349397398     PISSN: None     EISSN: 16765680     Source Type: Journal    
DOI: 10.4238/vol8-3gmr548     Document Type: Article

References (16)

1. Berry C, Thomas M, Langley B, Sharma M, et al. (2002). Single cysteine to tyrosine transition inactivates the growth inhibitory function of Piedmontese myostatin. Am. J. Physiol. Cell Physiol. 283: C135-C141.
2. Cappuccio I, Marchitelli C, Serracchioli A, Nardone A, et al. (1998). A G-T transversion introduces a stop codon at the mh locus in hypertrophy Marchigiana beef subjects. Anim. Genet. 29: 51.
3. Charlier C, Coppieters W, Farnir F, Grobet L, et al. (1995). The mh gene causing double-muscling in cattle maps to bovine chromosome 2. Mamm. Genome 6: 788-792.
4. Dunner S, Miranda ME, Amigues Y, Canon J, et al. (2003). Haplotype diversity of the myostatin gene among beef cattle breeds. Genet. Sel. Evol. 35: 103-118.
5. Ferrell RE, Conte V, Lawrence EC, Roth SM, et al. (1999). Frequent sequence variation in the human myostatin (GDF8) gene as a marker for analysis of muscle-related phenotypes. Genomics 62: 203-207.
6. Grobet L, Martin LJ, Poncelet D, Pirottin D, et al. (1997). A deletion in the bovine myostatin gene causes the double-muscled phenotype in cattle. Nat. Genet. 17: 71-74.
7. Grobet L, Poncelet D, Royo LJ, Brouwers B, et al. (1998). Molecular definition of an allelic series of mutations disrupting the myostatin function and causing double-muscling in cattle. Mamm. Genome 9: 210-213.
8. Jeanplong F, Sharma M, Somers WG, Bass JJ, et al. (2001). Genomic organization and neonatal expression of the bovine myostatin gene. Mol. Cell Biochem. 220: 31-37.
9. Kambadur R, Sharma M, Smith TP and Bass JJ (1997). Mutations in myostatin (GDF8) in double-muscled Belgian Blue and Piedmontese cattle. Genome Res. 7: 910-916.
10. Marchitelli C, Savarese MC, Crisa A, Nardone A, et al. (2003). Double muscling in Marchigiana beef breed is caused by a stop codon in the third exon of myostatin gene. Mamm. Genome 14: 392-395.
11. McPherron AC and Lee SJ (1997). Double muscling in cattle due to mutations in the myostatin gene. Proc. Natl. Acad. Sci U. S. A. 94: 12457-12461.
12. Mota LSLS, Curi RA, Palmieri DA and Borges AS (2005). Sequence characterization of coding regions of the myostatin gene (GDF8) from Brazilian Murrah buffaloes (Bubalus bubalis) and comparison with the Bos taurus sequence. Genet. Mol. Biol. 29: 79-82.
13. Sambrook J, Fritsch EF and Maniats T (1989). Molecular Cloning: a Laboratory Manual. 2nd edn. Cold Spring Harbor Laboratory Press, New York.
14. Shibata M, Ohshima K, Kojima T, Muramoto T, et al. (2003). Nucleotide sequence of myostatin gene and its developmental expression in skeletal muscles of Japanese Black cattle. Anim. Sci. J. 74: 383-390.
15. Smith TP, Lopez-Corrales NL, Kappes SM and Sonstegard TS (1997). Myostatin maps to the interval containing the bovine mh locus. Mamm. Genome 8: 742-744.
16. Thompson JD, Higgins DG and Gibson TJ (1994). CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice. Nucleic Acids Res. 22: 4673-4680.