Histochemical demonstration of monocarboxylate transporters in mouse brown adipose tissue

Biomedical Research

Volumn 30, Issue 4, 2009, Pages 217-225

  Iwanaga, Toshihiko ^a   Kuchiiwa, Takuya ^a   Saito, Masayuki ^b  

^a HOKKAIDO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b TENSHI COLLEGE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYL COENZYME A CARBOXYLASE; ACETYL COENZYME A CARBOXYLASE 2; CD147 ANTIGEN; MESSENGER RNA; MONOCARBOXYLATE TRANSPORTER; MONOCARBOXYLATE TRANSPORTER 1; UNCLASSIFIED DRUG;

ADIPOCYTE; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BROWN ADIPOSE TISSUE; CELL MEMBRANE; CONTROLLED STUDY; ELECTRON MICROSCOPY; FATTY ACID OXIDATION; FETUS; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; IN SITU HYBRIDIZATION; LIPOGENESIS; MALE; MOUSE; NEWBORN; NONHUMAN; NUCLEOTIDE SEQUENCE; PERINATAL PERIOD; PROTEIN ANALYSIS; PROTEIN EXPRESSION; THERMOGENESIS; WESTERN BLOTTING; WHITE ADIPOSE TISSUE;

ACETYL-COA CARBOXYLASE; ADIPOSE TISSUE, BROWN; ADIPOSE TISSUE, WHITE; ANIMALS; ANTIGENS, CD147; CELL MEMBRANE; GENE EXPRESSION REGULATION; IMMUNOHISTOCHEMISTRY; LIPOGENESIS; MALE; MICE; MONOCARBOXYLIC ACID TRANSPORTERS; ORGAN SPECIFICITY; SYMPORTERS; THERMOGENESIS;

ANIMALIA; MUS;

EID: 70349381447     PISSN: 03886107     EISSN: 1880313X     Source Type: Journal    
DOI: 10.2220/biomedres.30.217     Document Type: Article

References (30)

1. Abu-Elheiga L, Brinkley WR, Zhong L, Chirala SS, Woldegiorgis G and Wakil SJ (2000) The subcellular localization of acetyl-CoA carboxylase 2. Proc Natl Acad Sci USA 97, 1444-1449.
2. Abu-Elheiga L, Matzuk MM, Abo-Hasherna KA and Wakil SJ (2001) Continuous fatty acid oxidation and reduced fat storage in mice lacking acetyl-CoA carboxylase 2. Science 291, 2613-2616.
3. Abu-Elheiga L, Matzuk MM, Kordari P, Oh W, Shaikenov T, Gu Z and Wakil SJ (2005) Mutant mice lacking acetyl-CoA carboxylase 1 are embryonically lethal. Proc Natl Acad Sci USA 102, 12011-12016.
4. Cannon B and Nedergaard J (2004) Brown adipose tissue: function and physiological significance. Physiol Rev 84, 277-359.
5. Cinti S (1999) The Adipose Organ. Editrice Kurtis, Milano, Italy.
6. Cremer JE, Cunningham VJ, Pardridge WM, Braun LD and Oldendorf WH (1979) Kinetics of blood-brain barrier transport of pyruvate, lactate and glucose in suckling, weanling and adult rats. J Neurochem 33, 439-445.
7. Dombrowski GJ, Swiatek KR and Chao KL (1989) Lactate, 3-hydroxybutyrate, and glucose as substrates for the early postnatal rat brain. Neurochem Res 14, 667-680.
8. Eladari D, Chambrey R, Irinopoulou T, Leviel F, Pezy F, Bruneval P, Paillard M and Podevin R-A (1999) Polarized expression of different monocarboxylate transporters in rat medullary thick limbs of Henle. J Biol Chem 274, 28420-28426.
9. Garcia CK, Goldstein JL, Pathak RK, Anderson RGW and Brown MS (1994) Molecular characterization of a membrane transporter for lactate, pyruvate, and other monocarboxylates: implications for the Cori cycle. Cell 76, 865-873.
10. Garcia CK, Brown MS, Pathak RK and Goldstein JL (1995) cDNA cloning of MCT2, a second monocarboxylate transporter expressed in different cells than MCT1. J Biol Chem 270, 1843-1849.
11. Gerhart DZ, Enerson BE, Zhdankina OY, Leino RL and Drewes LR (1997) Expression of monocarboxylate transporter MCT1 by brain endothelium and glia in adult and suckling rats. Am J Phsiol (Endocrinol Metab 36) 273, E207-E213.
12. Halestrap AP and Meredith D (2004) The SLC16 gene family-from monocarboxylate transporters (MCTs) to aromatic amino acid transporters and beyond. Pflugers Arch 447, 619-628.
13. Hawkins RA, Williamson DH and Krebs HA (1971) Ketone-body utilization by adult and suckling rat brain in vivo. Biochem J 122, 13-18.
14. Hawkins RA, Mans AM and Davis DW (1986) Regional ketone body utilization by rat brain in starvation and diabetes. Am J Physiol 250, E169-E178.
15. Houstek J, Kopecky J, Rychter Z and Soukup T (1988) Uncoupling protein in embryonic brown adipose tissue-existence of nonthermogenic and thermogenic mitochondria. Biochim Biophys Acta 935, 19-25.
16. Iwanaga T, Takebe K, Kato I, Karaki S-I and Kuwahara A (2006) Cellular expression of monocarboxylate transporters (MCT) in the digestive tract of the mouse, rat, and humans, with special reference to slc5a8. Biomed Res 27, 243-254.
17. Jackson VN, Price NT, Carpenter L and Halestrap AP (1997) Cloning of the monocarboxylate transporter isoform MCT2 from rat testis provides evidence that expression in tissues is species-specific and may involve post-transcriptional regulation. Biochem J 324, 447-453.
18. Ježek P and Borecký J (1998) Mitochondrial uncoupling protein may participate in futile cycling of pyruvate and other monocarboxylates. Am J Physiol 275, C496-C504.
19. Meredith D and Christian HC (2008) The SLC16 monocarboxylate transporter family. Xenobiotica 38, 1072-1106.
20. Nagase I, Yoshida T, Kumamoto K, Umekawa T, Sakane N, Nikami H, Kawada T and Saito M (1996) Expression of uncoupling protein in skeletal muscle and white fat of obese mice treated with thermogenic β3-adrenergic agonist. J Clin Invest 97, 2898-2904.
21. Nikami H, Shimizu Y, Endoh D, Yano H and Saito M (1992) Cold exposure increases glucose utilization and glucose transporter expression in brown adipose tissue. Biochem Biophys Res Commun 185, 1078-1082.
22. Olichon-Berthe C, Van Obberghen E and Le Marchand-Brustel Y (1992) Effect of cold acclimation on the expression of glucose transporter Glut 4. Mol Cell Endocrinol 89, 11-18.
23. Price NT, Jackson VN and Halestrap AP (1998) Cloning and sequencing of four new mammalian monocarboxylate transporter (MCT) homologues confirms the existence of a transporter family with an ancient past. Biochem J 329, 321-328.
24. Shimizu Y, Nikami H, Tsukazaki K, Machado UF, Yano H, Seino Y, Saito M (1993) Increased expression of glucose transporter GLUT-4 in brown adipose tissue of fasted rats after cold exposure. Am J Physiol 264, E890-E895.
25. Simpson IA, Carruthers A and Vannucci SJ (2007) Supply and demand in cerebral energy metabolism: the role of nutrient transporters. J Cereb Blood Flow Metab 27, 1766-1791.
26. Takebe K, Nio-Kobayashi J, Takahashi-Iwanaga H and Iwanaga T (2008) Histochemical demonstration of a monocarboxylate transporter in the mouse perineurium with special reference to GLUT1. Biomed Res 29, 297-306.
27. Takebe K, Nio-Kobayashi J, Takahashi-Iwanaga H, Yajima T and Iwanaga T (2009) Cellular expression of a monocarboxylate transporter (MCT1) in the mammary gland and sebaceous gland of mice. Histochem Cell Biol 131, 401-409.
28. Teruel T, Valverde AM, Alvarez A, Benito M and Lorenzo M (1995) Differentiation of rat brown adipocytes during late foetal development: role of insulin-like growth factor I. Biochem J 310, 771-776.
29. Vannuci SJ and Simpson IA (2003) Developmental switch in brain nutrient transporter expression in the rat. Am J Physiol Endocrinol Metab 285, E1127-E1134.
30. Yanase H, Takebe K, Nio-Kobayashi J, Takahashi-Iwanaga H and Iwanaga T (2008) cellular expression of a sodium-dependent monocarboxylate transporter (Slc5a8) and the MCT family in the mouse kidney. Histochem Cell Biol 130, 957-966.