The Göttingen minipig for assessment of retinoid efficacy in the skin: Comparison of results from topically treated animals with results from organ-cultured skin

In Vitro Cellular and Developmental Biology - Animal

Volumn 45, Issue 9, 2009, Pages 551-557

  Dame, Michael K ^a   Paruchuri, Tejaswi ^a   Dasilva, Marissa ^a   Bhagavathula, Narasimharao ^a   Ridder, William ^b   Varani, James ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b Ricerca Inc   (United States)

Author keywords

Collagen; Matrix metalloproteinase; Minipig; Organ culture; Retinoid; Skin

Indexed keywords

COLLAGEN TYPE 1; GELATINASE A; GELATINASE B; MDI 301; RETINOID; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; COLLAGEN SYNTHESIS; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; COST EFFECTIVENESS ANALYSIS; DRUG EFFICACY; DRUG SAFETY; EPIDERMIS HYPERPLASIA; FEMALE; GOTTINGEN MINIPIG; HISTOLOGY; IN VITRO STUDY; IN VIVO STUDY; INTERMETHOD COMPARISON; MINIPIG; NONHUMAN; ORGAN CULTURE; SKIN IRRITATION; TOXICITY TESTING;

ADMINISTRATION, TOPICAL; ANIMALS; COLLAGEN TYPE I; EPIDERMIS; FEMALE; MATRIX METALLOPROTEINASE 2; ORGAN CULTURE TECHNIQUES; RETINOIDS; SKIN; SWINE; SWINE, MINIATURE;

ANIMALIA;

EID: 70349330423     PISSN: 10712690     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11626-009-9221-6     Document Type: Article

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