New tools to monitor the impact of viral infection on the alloreactive T-cell repertoire

Tissue Antigens

Volumn 74, Issue 4, 2009, Pages 290-297

  D'Orsogna, L J ^a   Amir, A L ^a   Zoet, Y M ^a   Van Der Meer Prins, P M W ^a   Van Der Slik, A R ^a   Kester, M G D ^a   Heemskerk, M H M ^a   Doxiadis, I I N ^a   Roelen, D L ^a   Claas, F H J ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Cross reactive alloresponse; Memory; Monitoring; T cells; Tolerance; Transplantation

Indexed keywords

CHROMIUM; GAMMA INTERFERON; MAJOR HISTOCOMPATIBILITY ANTIGEN; PHYTOHEMAGGLUTININ; T LYMPHOCYTE RECEPTOR;

ALLOIMMUNITY; ANTIGEN EXPRESSION; ARTICLE; CD8+ T LYMPHOCYTE; CELL CLONING; CELL SORTER; CONTROLLED STUDY; ENZYME LINKED IMMUNOSPOT ASSAY; EPSTEIN BARR VIRUS; GRAFT RECIPIENT; HUMAN; HUMAN CELL; MEMORY T LYMPHOCYTE; NORMAL HUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; T LYMPHOCYTE; VIRUS INFECTION;

ANTIGEN PRESENTATION; ANTIGENS, SURFACE; ANTIGENS, VIRAL; CD8-POSITIVE T-LYMPHOCYTES; CROSS REACTIONS; DNA PRIMERS; EPSTEIN-BARR VIRUS INFECTIONS; HERPESVIRUS 4, HUMAN; HLA ANTIGENS; HUMANS; IMMUNOLOGIC MEMORY; PEPTIDE FRAGMENTS; RECEPTORS, ANTIGEN, T-CELL; T-LYMPHOCYTES, CYTOTOXIC;

HUMAN HERPESVIRUS 4;

EID: 70349318452     PISSN: 00012815     EISSN: 13990039     Source Type: Journal    
DOI: 10.1111/j.1399-0039.2009.01311.x     Document Type: Article

References (42)

1. Welsh R, Selin L. No one is naïve: the significance of heterologous T-cell immunity. Nat Rev Immunol 2002 : 2 : 417 426.
2. Mason D. A very high level of cross-reactivity is an essential feature of the T-cell receptor. Immunol Today 1998 : 404 : 395 404.
3. Burrows S, Khanna R, Burrows J, Moss D. An alloresponse in humans is dominated by cytotoxic T-lymphocytes (CTL) cross-reactive with a single Epstein-Barr virus CTL epitope: implications for graft-vs-host disease. J Exp Med 1994 : 179 : 1155 1161.
4. Adams A, Williams M, Jones T et al. Heterologous immunity provides a potent barrier to transplantation tolerance. J Clin Invest 2003 : 111 : 1887 1895. (Pubitemid 38057733)
5. Brook M, Wood K, Jones N. The impact of memory T-cells on rejection and the induction of tolerance. Transplantation 2006 : 82 : 1 9.
6. Webb S, Sprent J. T-cells with multiple specificities. Int Rev Immunol 1986 : 1 : 151.
7. Gamadia L, Remmerswaal E, Surachno S et al. Cross-reactivity of cytomegalovirus-specific CD8+ T cells to allo-major histocompatability complex class I molecules. Transplantation 2004 : 77 : 1879 1885.
8. Koelle D, Chen H, McClurken C, Petersdorf E. Herpes simplex virus type 2-specific CD8 cytotoxic T lymphocyte cross-reactivity against prevalent HLA class I alleles. Blood 2002 : 99 : 3844 3847.
9. Landais E, Morice A, Long H et al. EBV-specific CD4+ T cell clones exhibit vigorous allogeneic responses. J Immunol 2006 : 177 : 1427 1433.
10. Blattman J, Antia R, Sourdive D et al. Estimating the precursor frequency of naïve antigen-specific CD8 T-cells. J Exp Med 2002 : 195 : 657 664.
11. Suchin E, Langmuir P, Palmer E, Sayegh M, Wells A, Turka L. Quantifying the frequency of alloreactive T cells in vivo: new answers to an old question. J Immunol 2001 : 166 : 973 981.
12. Janeway C, Lerner E, Conrad P, Jones B. The precision of self and non-self major histocompatability complex encoded antigen recognition by cloned T-cells. Behring Inst Mitt 1982 : 70 : 200.
13. Ashwell J, Chen C, Schwartz R. High frequency and non-random distribution of alloreactivity in T-cell clones selected for recognition of foreign antigen in association with self class II molecules. J Immunol 1986 : 136 : 389.
14. Lombardi G, Sidhu S, Daly M, Batchelor J, Makgoba W, Lechler R. Are primary alloresponses truly primary? Int Immunol 1989 : 2 : 9.
15. Zhang, Li S, Vandekerckhove B, Termijtelen A, Van Rood J, Claas F. Analysis of cytotoxic T-cell precursor frequencies directed against individual HLA-A and HLA-B alloantigens. J Immunol Methods 1989 : 121 : 39 45.
16. Selin L, Brehm M. Frontiers in nephrology: heterologous immunity, T cell cross reactivity and alloreactivity. J Am Soc Nephrol 2007 : 18 : 2268 2277.
17. Sheil J, Bevan M, Lefrancois L. Characterization of dual-reactive H-2Kb-restricted anti-vesicular stomatitis virus and alloreactive cytotoxic T cells. J Immunol 1987 : 138 : 3654 3660.
18. Yang H, Welsh R. Induction of alloreactive cytotoxic T cells by acute virus infection of mice. J Immunol 1986 : 136 : 1186 1193.
19. Braciale T, Andrew M, Braciale V. Simultaneous expression of H-2 restricted and alloreactive recognition by a cloned line of influenza virus-specific cytotoxic T lymphocytes. J Exp Med 1981 : 153 : 1371 1376. (Pubitemid 11107602)
20. Valujskikh A, Pantenburg B, Heeger P. Primed allospecific T cells prevent the effects of costimulatory blockade on prolonged cardiac allograft survival in mice. Am J Transplant 2002 : 2 : 501 509.
21. Hamann D, Baars P, Rep M et al. Phenotypic and functional separation of memory and effector human CD8+ T cells. J Exp Med 1997 : 186 : 1407 1418.
22. Byrne J, Butler J, Cooper M. Differential activation requirements for virgin and memory T cells. J Immunol 1988 : 141 : 3249 3257.
23. Sanders M, Makgoba M, June C, Young H, Shaw S. Enhanced responsiveness of human memory T cells to CD2 and CD3 receptor-mediated activation. Eur J Immunol 1989 : 19 : 803 808.
24. Picker L, Singh M, Zdraveski Z et al. Direct demonstration of cytokine synthesis heterogeneity among human memory/effector T cells by flow cytometry. Blood 1995 : 86 : 1408 1419.
25. Zoet Y, Eijsink C, Kardol M et al. The single antigen expressing lines (SALs) concept: an excellent tool for screening for HLA-specific antibodies. Hum Immunol 2005 : 66 : 519 525.
26. Mulder A, Zoet Y, Eijsink C et al. Single MHC antigen expressing cell lines for the definition of monoclonal antibody specificities. In : Hansen JA, ed. Histocompatability Testing 2002, HLA 2002. Munksgaard, 2005 : 92 105.
27. Heemskerk M, Hoogeboom M, Hagedoorn R, Kester M, Willemze R, Falkenburg J. Reprogramming of virus-specific T cells into leukemia-reactive T-cells using T cell receptor gene transfer. J Exp Med 2004 : 199 : 885 894.
28. Klein E, Benbassat H, Neumann H et al. Properties of K562 cell line, derived from a patient with chronic myeloid leukemia. Int J Cancer 1976 : 18 : 421.
29. Argaet V, Schimdt C, Burrows S et al. Dominant selection of an invariant T cell antigen receptor in response to persistent infection by Epstein-Barr virus. J Exp Med 1994 : 180 : 2335 2340.
30. Parham P, Lomen C, Lawler D et al. Nature of polymorphisms in HLA-A, -B and -C molecules. Proc Natl Acad Sci U S A 1988 : 85 : 4005 4010.
31. European Bioinformatics Institute. International Immunogenetics Project. http://www.ebi.ac.uk/imgt/hla/.
32. Burrows S, Khanna R, Silins S, Moss D. The influence of antiviral T-cell responses on the alloreactive repertoire. Immunol Today 1999 : 20 : 203 207.
33. Archbold J, Macdonald W, Miles J et al. Alloreactivity between disparate cognate and allogeneic pMHC-I complexes is the result of highly focused, peptide-dependent structural mimicry. J Biol Chem 2006 : 281 : 34324 34332.
34. Burrows S, Silins S, Khanna R et al. Cross-reactive memory T-cells for Epstein-Barr virus augment the alloresponse to common human leukocyte antigens: degenerate recognition of major histocompatability complex-bound peptide by T cells and its role in alloreactivity. Eur J Immunol 1997 : 27 : 1726 1736.
35. van der Stoep N, Biesta P, Quinten E, van den Elsen P. Lack of IFNγ mediated induction of the class II transactivator (CIITA) through promoter methylation is predominantly found in developmental tumor cell Lines. Int J Cancer 2002 : 97 : 501 507.
36. Maruya E, Takemoto S, Terasaki P. HLA matching: identification of permissible HLA mismatches. Clin Transpl 1993 : 9 : 511 520.
37. van der Boogaardt D, van Miert P, de Vaal Y, Fijter J, Claas F, Roelen D. The ratio of interferon-γ and interleukin-10 producing donor-specific cells as an in vitro monitoring tool for renal transplant patients. Transplantation 2006 : 82 : 844 848.
38. Heeger P, Greenspan N, Kuhlenschmidt S et al. Pretransplant frequency of donor-specific, IFNγ-producing lymphocytes is a manifestation of immunologic memory and correlates with the risk of posttransplant rejection episodes. J Immunol 1999 : 163 : 2267 2275.
39. Andree H, Nickel P, Nasiadko C et al. Identification of dialysis patients with panel-reactive memory T-cells before kidney transplantation using an allogeneic cell bank. J Am Soc Nephrol 2006 : 17 : 573 580.
40. Poggio E, Clemente M, Hricik D, Heeger P. Panel of reactive T cells as a measurement of primed cellular alloimmunity in kidney transplant candidates. J Am Soc Nephrol 2006 : 17 : 564 572.
41. Burrows S, Khanna R, Moss D. Direct alloreactivity by human T lymphocytes can be inhibited by altered peptide ligand antagonism. Blood 1999 : 93 : 1020 1024.
42. Kleim V, Fricke L, Wollbrink T, Burg M, Radermacher J, Rohde F. Improvement in long-term renal graft survival due to CMV prophylaxis with oral ganciclovir: results of a randomized clinical trial. Am J Transplant 2008 : 8 : 975 983.