-
2
-
-
14944385553
-
Global cancer statistics, 2002
-
Parkin DM, Bray F, Ferlay J and Pisani P: Global cancer statistics, 2002. CA Cancer J Clin 55: 74-108, 2005.
-
(2005)
CA Cancer J Clin
, vol.55
, pp. 74-108
-
-
Parkin, D.M.1
Bray, F.2
Ferlay, J.3
Pisani, P.4
-
4
-
-
0033305213
-
Peroxisome proliferator-activated receptors: Nuclear control of metabolism
-
Desvergne B and Wahli W: Peroxisome proliferator-activated receptors: nuclear control of metabolism. Endocr Rev 20: 649-688, 1999.
-
(1999)
Endocr Rev
, vol.20
, pp. 649-688
-
-
Desvergne, B.1
Wahli, W.2
-
5
-
-
1942518840
-
PPARs and the complex journey to obesity
-
Evans RM, Barish GD and Wang YX: PPARs and the complex journey to obesity. Nat Med 10: 355-361, 2004.
-
(2004)
Nat Med
, vol.10
, pp. 355-361
-
-
Evans, R.M.1
Barish, G.D.2
Wang, Y.X.3
-
6
-
-
0025132245
-
Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators
-
Issemann I and Green S: Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators. Nature 347: 645-650, 1990.
-
(1990)
Nature
, vol.347
, pp. 645-650
-
-
Issemann, I.1
Green, S.2
-
7
-
-
0028972025
-
15-Deoxy-delta 12, 14-prostaglandin J2 is a ligand for the adipocyte determination factor PPAR gamma
-
Forman BM, Tontonoz P, Chen J, Brun RP, Spiegelman BM and Evans RM: 15-Deoxy-delta 12, 14-prostaglandin J2 is a ligand for the adipocyte determination factor PPAR gamma. Cell 83: 803-812, 1995.
-
(1995)
Cell
, vol.83
, pp. 803-812
-
-
Forman, B.M.1
Tontonoz, P.2
Chen, J.3
Brun, R.P.4
Spiegelman, B.M.5
Evans, R.M.6
-
8
-
-
12944319827
-
The effects of rosiglitazone on fatty acid and triglyceride metabolism in type 2 diabetes
-
Tan GD, Fielding BA, Currie JM, et al: The effects of rosiglitazone on fatty acid and triglyceride metabolism in type 2 diabetes. Diabetologia 48: 83-95, 2005.
-
(2005)
Diabetologia
, vol.48
, pp. 83-95
-
-
Tan, G.D.1
Fielding, B.A.2
Currie, J.M.3
-
9
-
-
0033625677
-
Growth, adipose, brain, and skin alterations resulting from targeted disruption of the mouse peroxisome proliferator-activated receptor beta(delta)
-
Peters JM, Lee SS, Li W, et al: Growth, adipose, brain, and skin alterations resulting from targeted disruption of the mouse peroxisome proliferator-activated receptor beta(delta). Mol Cell Biol 20: 5119-5128, 2000.
-
(2000)
Mol Cell Biol
, vol.20
, pp. 5119-5128
-
-
Peters, J.M.1
Lee, S.S.2
Li, W.3
-
10
-
-
0037039374
-
Effects of peroxisome proliferator-activated receptor delta on placentation, adiposity and colorectal cancer
-
Barak Y, Liao D, He W, et al: Effects of peroxisome proliferator-activated receptor delta on placentation, adiposity and colorectal cancer. Proc Natl Acad Sci USA 99: 303-308, 2002.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 303-308
-
-
Barak, Y.1
Liao, D.2
He, W.3
-
11
-
-
9144262378
-
Cardiomyocyte-restricted peroxisome proliferator-activated receptor-delta deletion perturbs myocardial fatty acid oxidation and leads to cardiomyopathy
-
Cheng L, Ding G, Qin Q, et al: Cardiomyocyte-restricted peroxisome proliferator-activated receptor-delta deletion perturbs myocardial fatty acid oxidation and leads to cardiomyopathy. Nat Med 10: 1245-1250, 2004.
-
(2004)
Nat Med
, vol.10
, pp. 1245-1250
-
-
Cheng, L.1
Ding, G.2
Qin, Q.3
-
12
-
-
33644766913
-
PPARdelta regulates glucose metabolism and insulin sensitivity
-
Lee CH, Olson P, Hevener A, et al: PPARdelta regulates glucose metabolism and insulin sensitivity. Proc Natl Acad Sci USA 103: 3444-3449, 2006.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 3444-3449
-
-
Lee, C.H.1
Olson, P.2
Hevener, A.3
-
13
-
-
8844276054
-
Regulation of muscle fiber type and running endurance by PPARdelta
-
Wang YX, Zhang CL, Yu RT, et al: Regulation of muscle fiber type and running endurance by PPARdelta. PLoS Biol 2: E294, 2004.
-
(2004)
PLoS Biol
, vol.2
-
-
Wang, Y.X.1
Zhang, C.L.2
Yu, R.T.3
-
14
-
-
0142116239
-
Transcriptional repression of atherogenic inflammation: Modulation by PPARdelta
-
Lee CH, Chawla A, Urbiztondo N, et al: Transcriptional repression of atherogenic inflammation: modulation by PPARdelta. Science 302: 453-457, 2003.
-
(2003)
Science
, vol.302
, pp. 453-457
-
-
Lee, C.H.1
Chawla, A.2
Urbiztondo, N.3
-
15
-
-
0034278508
-
BCL-6 regulates chemokine gene transcription in macrophages
-
Toney LM, Cattoretti G, Graf JA, et al: BCL-6 regulates chemokine gene transcription in macrophages. Nat Immunol 1: 214-220, 2000.
-
(2000)
Nat Immunol
, vol.1
, pp. 214-220
-
-
Toney, L.M.1
Cattoretti, G.2
Graf, J.A.3
-
16
-
-
36849000746
-
Inhibition of interleukin-1beta-induced group IIA secretory phospholipase A2 expression by peroxisome proliferator-activated receptors (PPARs) in rat vascular smooth muscle cells: Cooperation between PPARbeta and the protooncogene BCL-6
-
Ravaux L, Denoyelle C, Monne C, Limon I, Raymondjean M and El Hadri K: Inhibition of interleukin-1beta-induced group IIA secretory phospholipase A2 expression by peroxisome proliferator-activated receptors (PPARs) in rat vascular smooth muscle cells: cooperation between PPARbeta and the protooncogene BCL-6. Mol Cell Biol 27: 8374-8387, 2007.
-
(2007)
Mol Cell Biol
, vol.27
, pp. 8374-8387
-
-
Ravaux, L.1
Denoyelle, C.2
Monne, C.3
Limon, I.4
Raymondjean, M.5
El Hadri, K.6
-
17
-
-
0033105510
-
Molecular recognition of fatty acids by peroxisome proliferator-activated receptors
-
Xu HE, Lambert MH, Montana VG, et al: Molecular recognition of fatty acids by peroxisome proliferator-activated receptors. Mol Cell 3: 397-403, 1999.
-
(1999)
Mol Cell
, vol.3
, pp. 397-403
-
-
Xu, H.E.1
Lambert, M.H.2
Montana, V.G.3
-
18
-
-
0030952937
-
Hypolipidemic drugs, polyunsaturated fatty acids and eicosanoids are ligands for peroxisome proliferator-activated receptors alpha and delta
-
Forman BM, Chen J and Evans RM: Hypolipidemic drugs, polyunsaturated fatty acids and eicosanoids are ligands for peroxisome proliferator-activated receptors alpha and delta. Proc Natl Acad Sci USA 94: 4312-4317, 1997.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 4312-4317
-
-
Forman, B.M.1
Chen, J.2
Evans, R.M.3
-
19
-
-
0028802627
-
Differential activation of peroxisome proliferator-activated receptors by eicosanoids
-
Yu K, Bayona W, Kallen CB, et al: Differential activation of peroxisome proliferator-activated receptors by eicosanoids. J Biol Chem 270: 23975-23983, 1995.
-
(1995)
J Biol Chem
, vol.270
, pp. 23975-23983
-
-
Yu, K.1
Bayona, W.2
Kallen, C.B.3
-
20
-
-
0030985318
-
Fatty acids, eicosanoids and hypolipidemic agents identified as ligands of peroxisome proliferator-activated receptors by coactivator-dependent receptor ligand assay
-
Krey G, Braissant O, L'Horset F, et al: Fatty acids, eicosanoids and hypolipidemic agents identified as ligands of peroxisome proliferator-activated receptors by coactivator-dependent receptor ligand assay. Mol Endocrinol 11: 779-791, 1997.
-
(1997)
Mol Endocrinol
, vol.11
, pp. 779-791
-
-
Krey, G.1
Braissant, O.2
L'Horset, F.3
-
21
-
-
0037417726
-
PPARdelta is a very low-density lipoprotein sensor in macrophages
-
Chawla A, Lee CH, Barak Y, et al: PPARdelta is a very low-density lipoprotein sensor in macrophages. Proc Natl Acad Sci USA 100: 1268-1273, 2003.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 1268-1273
-
-
Chawla, A.1
Lee, C.H.2
Barak, Y.3
-
22
-
-
33644645013
-
PPAR delta: A dagger in the heart of the metabolic syndrome
-
Barish GD, Narkar VA and Evans RM: PPAR delta: a dagger in the heart of the metabolic syndrome. J Clin Invest 116: 590-597, 2006.
-
(2006)
J Clin Invest
, vol.116
, pp. 590-597
-
-
Barish, G.D.1
Narkar, V.A.2
Evans, R.M.3
-
23
-
-
2542421984
-
Peroxisome proliferator-activated receptor beta (delta)-dependent regulation of ubiquitin C expression contributes to attenuation of skin carcinogenesis
-
Kim DJ, Akiyama TE, Harman FS, et al: Peroxisome proliferator-activated receptor beta (delta)-dependent regulation of ubiquitin C expression contributes to attenuation of skin carcinogenesis. J Biol Chem 279: 23719-23727, 2004.
-
(2004)
J Biol Chem
, vol.279
, pp. 23719-23727
-
-
Kim, D.J.1
Akiyama, T.E.2
Harman, F.S.3
-
24
-
-
21244437199
-
Peroxisome proliferator-activated receptor delta as a molecular target to regulate lung cancer cell growth
-
Fukumoto K, Yano Y, Virgona N, et al: Peroxisome proliferator-activated receptor delta as a molecular target to regulate lung cancer cell growth. FEBS Lett 579: 3829-3836, 2005.
-
(2005)
FEBS Lett
, vol.579
, pp. 3829-3836
-
-
Fukumoto, K.1
Yano, Y.2
Virgona, N.3
-
25
-
-
2442708845
-
Peroxisome proliferator-activated receptor-delta attenuates colon carcinogenesis
-
Harman FS, Nicol CJ, Marin HE, Ward JM, Gonzalez FJ and Peters JM: Peroxisome proliferator-activated receptor-delta attenuates colon carcinogenesis. Nat Med 10: 481-483, 2004.
-
(2004)
Nat Med
, vol.10
, pp. 481-483
-
-
Harman, F.S.1
Nicol, C.J.2
Marin, H.E.3
Ward, J.M.4
Gonzalez, F.J.5
Peters, J.M.6
-
26
-
-
15744366162
-
Peroxisome proliferator-activated receptor-beta/delta inhibits epidermal cell proliferation by down-regulation of kinase activity
-
Kim DJ, Murray IA, Burns AM, Gonzalez FJ, Perdew GH and Peters JM: Peroxisome proliferator-activated receptor-beta/delta inhibits epidermal cell proliferation by down-regulation of kinase activity. J Biol Chem 280: 9519-9527, 2005.
-
(2005)
J Biol Chem
, vol.280
, pp. 9519-9527
-
-
Kim, D.J.1
Murray, I.A.2
Burns, A.M.3
Gonzalez, F.J.4
Perdew, G.H.5
Peters, J.M.6
-
27
-
-
18144384743
-
Peroxisome proliferator-activated receptor delta and gamma agonists differentially alter tumor differentiation and progression during mammary carcinogenesis
-
Yin Y, Russell RG, Dettin LE, et al: Peroxisome proliferator-activated receptor delta and gamma agonists differentially alter tumor differentiation and progression during mammary carcinogenesis. Cancer Res 65: 3950-3957, 2005.
-
(2005)
Cancer Res
, vol.65
, pp. 3950-3957
-
-
Yin, Y.1
Russell, R.G.2
Dettin, L.E.3
-
28
-
-
2342640982
-
Activation of peroxisome proliferator-activated receptor delta stimulates the proliferation of human breast and prostate cancer cell lines
-
Stephen RL, Gustafsson MC, Jarvis M, et al: Activation of peroxisome proliferator-activated receptor delta stimulates the proliferation of human breast and prostate cancer cell lines. Cancer Res 64: 3162-3170, 2004.
-
(2004)
Cancer Res
, vol.64
, pp. 3162-3170
-
-
Stephen, R.L.1
Gustafsson, M.C.2
Jarvis, M.3
-
29
-
-
0042388005
-
PPARdelta activation induces COX-2 gene expression and cell proliferation in human hepatocellular carcinoma cells
-
Glinghammar B, Skogsberg J, Hamsten A and Ehrenborg E: PPARdelta activation induces COX-2 gene expression and cell proliferation in human hepatocellular carcinoma cells. Biochem Biophys Res Commun 308: 361-368, 2003.
-
(2003)
Biochem Biophys Res Commun
, vol.308
, pp. 361-368
-
-
Glinghammar, B.1
Skogsberg, J.2
Hamsten, A.3
Ehrenborg, E.4
-
30
-
-
33846221464
-
Cross-talk between peroxisome proliferator-activated receptor delta and cytosolic phospholipase A(2)alpha/cyclooxygenase-2/prostaglandin E(2) signaling pathways in human hepatocellular carcinoma cells
-
Xu L, Han C, Lim K and Wu T: Cross-talk between peroxisome proliferator-activated receptor delta and cytosolic phospholipase A(2)alpha/cyclooxygenase-2/prostaglandin E(2) signaling pathways in human hepatocellular carcinoma cells. Cancer Res 66: 11859-11868, 2006.
-
(2006)
Cancer Res
, vol.66
, pp. 11859-11868
-
-
Xu, L.1
Han, C.2
Lim, K.3
Wu, T.4
-
31
-
-
1942470331
-
Activation of nuclear hormone receptor peroxisome proliferator-activated receptor-delta accelerates intestinal adenoma growth
-
Gupta RA, Wang D, Katkuri S, Wang H, Dey SK and DuBois RN: Activation of nuclear hormone receptor peroxisome proliferator-activated receptor-delta accelerates intestinal adenoma growth. Nat Med 10: 245-247, 2004.
-
(2004)
Nat Med
, vol.10
, pp. 245-247
-
-
Gupta, R.A.1
Wang, D.2
Katkuri, S.3
Wang, H.4
Dey, S.K.5
DuBois, R.N.6
-
32
-
-
0042692791
-
The 15-lipoxygenase-1 product 13-S-hydroxyoctadecadienoic acid down-regulates PPAR-delta to induce apoptosis in colorectal cancer cells
-
Shureiqi I, Jiang W, Zuo X, et al: The 15-lipoxygenase-1 product 13-S-hydroxyoctadecadienoic acid down-regulates PPAR-delta to induce apoptosis in colorectal cancer cells. Proc Natl Acad Sci USA 100: 9968-9973, 2003.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 9968-9973
-
-
Shureiqi, I.1
Jiang, W.2
Zuo, X.3
-
33
-
-
0035956850
-
Genetic disruption of PPARdelta decreases the tumorigenicity of human colon cancer cells
-
Park BH, Vogelstein B and Kinzler KW: Genetic disruption of PPARdelta decreases the tumorigenicity of human colon cancer cells. Proc Natl Acad Sci USA 98: 2598-2603, 2001.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 2598-2603
-
-
Park, B.H.1
Vogelstein, B.2
Kinzler, K.W.3
-
34
-
-
0036606010
-
Peroxisome proliferator-activated receptors modulate K-Ras-mediated transformation of intestinal epithelial cells
-
Shao J, Sheng H and DuBois RN: Peroxisome proliferator-activated receptors modulate K-Ras-mediated transformation of intestinal epithelial cells. Cancer Res 62: 3282-3288, 2002.
-
(2002)
Cancer Res
, vol.62
, pp. 3282-3288
-
-
Shao, J.1
Sheng, H.2
DuBois, R.N.3
-
35
-
-
33748678896
-
Gastric cancer: Global pattern of the disease and an overview of environmental risk factors
-
Forman D and Burley VJ: Gastric cancer: global pattern of the disease and an overview of environmental risk factors. Best Pract Res Clin Gastroenterol 20: 633-649, 2006.
-
(2006)
Best Pract Res Clin Gastroenterol
, vol.20
, pp. 633-649
-
-
Forman, D.1
Burley, V.J.2
-
36
-
-
33744527899
-
Helicobacter pylori infection causes gastric cancer? A review of the epidemiological, meta-analytic and experimental evidence
-
Eslick GD: Helicobacter pylori infection causes gastric cancer? A review of the epidemiological, meta-analytic and experimental evidence. World J Gastroenterol 12: 2991-2999, 2006.
-
(2006)
World J Gastroenterol
, vol.12
, pp. 2991-2999
-
-
Eslick, G.D.1
-
37
-
-
33749385403
-
-
Prinz C, Schwendy S and Voland P: H. pylori and gastric cancer: shifting the global burden. World J Gastroenterol 12: 5458-5464, 2006.
-
Prinz C, Schwendy S and Voland P: H. pylori and gastric cancer: shifting the global burden. World J Gastroenterol 12: 5458-5464, 2006.
-
-
-
-
39
-
-
34548746356
-
Interaction of MUC1 with beta-catenin modulates the Wnt target gene cyclinD1 in H. pylori-induced gastric cancer
-
Udhayakumar G, Jayanthi V, Devaraj N and Devaraj H: Interaction of MUC1 with beta-catenin modulates the Wnt target gene cyclinD1 in H. pylori-induced gastric cancer. Mol Carcinog 46: 807-817, 2007.
-
(2007)
Mol Carcinog
, vol.46
, pp. 807-817
-
-
Udhayakumar, G.1
Jayanthi, V.2
Devaraj, N.3
Devaraj, H.4
-
40
-
-
34250371506
-
Pathogenesis of Helicobacter pylori infection
-
Hatakeyama M and Brzozowski T: Pathogenesis of Helicobacter pylori infection. Helicobacter 11 (Suppl. 1): S14-S20, 2006.
-
(2006)
Helicobacter
, vol.11
, Issue.SUPPL. 1
-
-
Hatakeyama, M.1
Brzozowski, T.2
-
41
-
-
25844451675
-
Inflammation, immunity, and vaccines for Helicobacter infection
-
Permin H and Andersen LP: Inflammation, immunity, and vaccines for Helicobacter infection. Helicobacter 10 (Suppl. 1): S21-S25, 2005.
-
(2005)
Helicobacter
, vol.10
, Issue.SUPPL. 1
-
-
Permin, H.1
Andersen, L.P.2
-
42
-
-
33744552272
-
Genetic variants in cyclooxygenase-2: Expression and risk of gastric cancer and its precursors in a Chinese population
-
Liu F, Pan K, Zhang X, et al: Genetic variants in cyclooxygenase-2: Expression and risk of gastric cancer and its precursors in a Chinese population. Gastroenterology 130: 1975-1984, 2006.
-
(2006)
Gastroenterology
, vol.130
, pp. 1975-1984
-
-
Liu, F.1
Pan, K.2
Zhang, X.3
-
43
-
-
0028353941
-
Risks of bleeding peptic ulcer associated with individual non-steroidal anti-inflammatory drugs
-
Langman MJ, Weil J, Wainwright P, et al: Risks of bleeding peptic ulcer associated with individual non-steroidal anti-inflammatory drugs. Lancet 343: 1075-1078, 1994.
-
(1994)
Lancet
, vol.343
, pp. 1075-1078
-
-
Langman, M.J.1
Weil, J.2
Wainwright, P.3
-
44
-
-
20144365496
-
Cardiovascular risk associated with celecoxib in a clinical trial for colorectal adenoma prevention
-
Solomon SD, McMurray JJ, Pfeffer MA, et al: Cardiovascular risk associated with celecoxib in a clinical trial for colorectal adenoma prevention. N Engl J Med 352: 1071-1080, 2005.
-
(2005)
N Engl J Med
, vol.352
, pp. 1071-1080
-
-
Solomon, S.D.1
McMurray, J.J.2
Pfeffer, M.A.3
-
45
-
-
19744380776
-
Cardiovascular events associated with rofecoxib in a colorectal adenoma chemoprevention trial
-
Bresalier RS, Sandler RS, Quan H, et al: Cardiovascular events associated with rofecoxib in a colorectal adenoma chemoprevention trial. N Engl J Med 352: 1092-1102, 2005.
-
(2005)
N Engl J Med
, vol.352
, pp. 1092-1102
-
-
Bresalier, R.S.1
Sandler, R.S.2
Quan, H.3
-
46
-
-
18844439118
-
Expression of peroxisome proliferator-activated receptor delta in human gastric cancer and its response to specific COX-2 inhibitor
-
Yu J, Leung WK, Chen J, Ebert MP, Malfertheiner P and Sung JJ: Expression of peroxisome proliferator-activated receptor delta in human gastric cancer and its response to specific COX-2 inhibitor. Cancer Lett 223: 11-17, 2005.
-
(2005)
Cancer Lett
, vol.223
, pp. 11-17
-
-
Yu, J.1
Leung, W.K.2
Chen, J.3
Ebert, M.P.4
Malfertheiner, P.5
Sung, J.J.6
-
47
-
-
0030613555
-
IkappaB kinase: Beginning, not the end
-
Verma IM and Stevenson J: IkappaB kinase: beginning, not the end. Proc Natl Acad Sci USA 94: 11758-11760, 1997.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 11758-11760
-
-
Verma, I.M.1
Stevenson, J.2
-
48
-
-
34147180434
-
Helicobacter pylori infection triggers aberrant expression of activation-induced cytidine deaminase in gastric epithelium
-
Matsumoto Y, Marusawa H, Kinoshita K, et al: Helicobacter pylori infection triggers aberrant expression of activation-induced cytidine deaminase in gastric epithelium. Nat Med 13: 470-476, 2007.
-
(2007)
Nat Med
, vol.13
, pp. 470-476
-
-
Matsumoto, Y.1
Marusawa, H.2
Kinoshita, K.3
-
49
-
-
0037168869
-
PPARalpha and PPARdelta activators inhibit cytokine-induced nuclear translocation of NF-kappaB and expression of VCAM-1 in EAhy926 endothelial cells
-
Rival Y, Beneteau N, Taillandier T, et al: PPARalpha and PPARdelta activators inhibit cytokine-induced nuclear translocation of NF-kappaB and expression of VCAM-1 in EAhy926 endothelial cells. Eur J Pharmacol 435: 143-151, 2002.
-
(2002)
Eur J Pharmacol
, vol.435
, pp. 143-151
-
-
Rival, Y.1
Beneteau, N.2
Taillandier, T.3
-
50
-
-
38649104434
-
Peroxisome proliferator-activated receptor-beta/delta protects against chemically induced liver toxicity in mice
-
Shan W, Nicol CJ, Ito S, et al: Peroxisome proliferator-activated receptor-beta/delta protects against chemically induced liver toxicity in mice. Hepatology 47: 225-235, 2008.
-
(2008)
Hepatology
, vol.47
, pp. 225-235
-
-
Shan, W.1
Nicol, C.J.2
Ito, S.3
-
51
-
-
13844256366
-
Peroxisome proliferator-activated receptor beta/delta activation inhibits hypertrophy in neonatal rat cardiomyocytes
-
Planavila A, Rodriguez-Calvo R, Jove M, et al: Peroxisome proliferator-activated receptor beta/delta activation inhibits hypertrophy in neonatal rat cardiomyocytes. Cardiovasc Res 65: 832-841, 2005.
-
(2005)
Cardiovasc Res
, vol.65
, pp. 832-841
-
-
Planavila, A.1
Rodriguez-Calvo, R.2
Jove, M.3
-
52
-
-
0036893170
-
Effect of interleukin 1 polymorphisms on gastric mucosal interleukin 1beta production in Helicobacter pylori infection
-
Hwang IR, Kodama T, Kikuchi S, et al: Effect of interleukin 1 polymorphisms on gastric mucosal interleukin 1beta production in Helicobacter pylori infection. Gastroenterology 123: 1793-1803, 2002.
-
(2002)
Gastroenterology
, vol.123
, pp. 1793-1803
-
-
Hwang, I.R.1
Kodama, T.2
Kikuchi, S.3
-
53
-
-
0345528036
-
Association of interleukin 1B gene polymorphism and gastric cancers in high and low prevalence regions in China
-
Zeng ZR, Hu PJ, Hu S, et al: Association of interleukin 1B gene polymorphism and gastric cancers in high and low prevalence regions in China. Gut 52: 1684-1689, 2003.
-
(2003)
Gut
, vol.52
, pp. 1684-1689
-
-
Zeng, Z.R.1
Hu, P.J.2
Hu, S.3
-
54
-
-
17744418769
-
The effect of celecoxib, a cyclooxygenase-2 inhibitor, in familial adenomatous polyposis
-
Steinbach G, Lynch PM, Phillips RK, et al: The effect of celecoxib, a cyclooxygenase-2 inhibitor, in familial adenomatous polyposis. N Engl J Med 342: 1946-1952, 2000.
-
(2000)
N Engl J Med
, vol.342
, pp. 1946-1952
-
-
Steinbach, G.1
Lynch, P.M.2
Phillips, R.K.3
-
55
-
-
11144356955
-
Cyclooxygenase-2 expression correlates with angiogenesis and apoptosis in gastric cancer tissue
-
Tatsuguchi A, Matsui K, Shinji Y, et al: Cyclooxygenase-2 expression correlates with angiogenesis and apoptosis in gastric cancer tissue. Hum Pathol 35: 488-495, 2004.
-
(2004)
Hum Pathol
, vol.35
, pp. 488-495
-
-
Tatsuguchi, A.1
Matsui, K.2
Shinji, Y.3
-
56
-
-
3042674629
-
Cyclooxygenase-2 upregulates vascular endothelial growth factor expression and angiogenesis in human gastric carcinoma
-
Leung WK, To KF, Go MY, et al: Cyclooxygenase-2 upregulates vascular endothelial growth factor expression and angiogenesis in human gastric carcinoma. Int J Oncol 23: 1317-1322, 2003.
-
(2003)
Int J Oncol
, vol.23
, pp. 1317-1322
-
-
Leung, W.K.1
To, K.F.2
Go, M.Y.3
-
57
-
-
0033082201
-
Cyclooxygenase-2 overexpression enhances lymphatic invasion and metastasis in human gastric carcinoma
-
Murata H, Kawano S, Tsuji S, et al: Cyclooxygenase-2 overexpression enhances lymphatic invasion and metastasis in human gastric carcinoma. Am J Gastroenterol 94: 451-455, 1999.
-
(1999)
Am J Gastroenterol
, vol.94
, pp. 451-455
-
-
Murata, H.1
Kawano, S.2
Tsuji, S.3
-
58
-
-
1642451874
-
Chemoprevention of gastric cancer by celecoxib in rats
-
Hu PJ, Yu J, Zeng ZR, et al: Chemoprevention of gastric cancer by celecoxib in rats. Gut 53: 195-200, 2004.
-
(2004)
Gut
, vol.53
, pp. 195-200
-
-
Hu, P.J.1
Yu, J.2
Zeng, Z.R.3
-
59
-
-
36949036752
-
Peroxisome proliferator-activated receptor-beta/delta (PPARbeta/delta) ligands do not potentiate growth of human cancer cell lines
-
Hollingshead HE, Killins RL, Borland MG, et al: Peroxisome proliferator-activated receptor-beta/delta (PPARbeta/delta) ligands do not potentiate growth of human cancer cell lines. Carcinogenesis 28: 2641-2649, 2007.
-
(2007)
Carcinogenesis
, vol.28
, pp. 2641-2649
-
-
Hollingshead, H.E.1
Killins, R.L.2
Borland, M.G.3
-
60
-
-
4544320012
-
Prostaglandin E(2) promotes colorectal adenoma growth via transactivation of the nuclear peroxisome proliferator-activated receptor delta
-
Wang D, Wang H, Shi Q, et al: Prostaglandin E(2) promotes colorectal adenoma growth via transactivation of the nuclear peroxisome proliferator-activated receptor delta. Cancer Cell 6: 285-295, 2004.
-
(2004)
Cancer Cell
, vol.6
, pp. 285-295
-
-
Wang, D.1
Wang, H.2
Shi, Q.3
-
61
-
-
0025909734
-
Identification of a gene located at chromosome 5q21 that is mutated in colorectal cancers
-
Kinzler KW, Nilbert MC, Vogelstein B, et al: Identification of a gene located at chromosome 5q21 that is mutated in colorectal cancers. Science 251: 1366-1370, 1991.
-
(1991)
Science
, vol.251
, pp. 1366-1370
-
-
Kinzler, K.W.1
Nilbert, M.C.2
Vogelstein, B.3
-
62
-
-
0025899162
-
Mutations of chromosome 5q21 genes in FAP and colorectal cancer patients
-
Nishisho I, Nakamura Y, Miyoshi Y, et al: Mutations of chromosome 5q21 genes in FAP and colorectal cancer patients. Science 253: 665-669, 1991.
-
(1991)
Science
, vol.253
, pp. 665-669
-
-
Nishisho, I.1
Nakamura, Y.2
Miyoshi, Y.3
-
63
-
-
0033615352
-
PPARdelta is an APC-regulated target of non-steroidal anti-inflammatory drugs
-
He TC, Chan TA, Vogelstein B and Kinzler KW: PPARdelta is an APC-regulated target of non-steroidal anti-inflammatory drugs. Cell 99: 335-345, 1999.
-
(1999)
Cell
, vol.99
, pp. 335-345
-
-
He, T.C.1
Chan, T.A.2
Vogelstein, B.3
Kinzler, K.W.4
-
64
-
-
0032483439
-
Identification of c-MYC as a target of the APC pathway
-
He TC, Sparks AB, Rago C, et al: Identification of c-MYC as a target of the APC pathway. Science 281: 1509-1512, 1998.
-
(1998)
Science
, vol.281
, pp. 1509-1512
-
-
He, T.C.1
Sparks, A.B.2
Rago, C.3
-
65
-
-
0033119801
-
Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells
-
Tetsu O and McCormick F: Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells. Nature 398: 422-426, 1999.
-
(1999)
Nature
, vol.398
, pp. 422-426
-
-
Tetsu, O.1
McCormick, F.2
-
66
-
-
0026734665
-
The APC gene, responsible for familial adenomatous polyposis, is mutated in human gastric cancer
-
Horii A, Nakatsuru S, Miyoshi Y, et al: The APC gene, responsible for familial adenomatous polyposis, is mutated in human gastric cancer. Cancer Res 52: 3231-3233, 1992.
-
(1992)
Cancer Res
, vol.52
, pp. 3231-3233
-
-
Horii, A.1
Nakatsuru, S.2
Miyoshi, Y.3
-
67
-
-
0036193127
-
Increased beta-catenin mRNA levels and mutational alterations of the APC and beta-catenin gene are present in intestinal-type gastric cancer
-
Ebert MP, Fei G, Kahmann S, et al: Increased beta-catenin mRNA levels and mutational alterations of the APC and beta-catenin gene are present in intestinal-type gastric cancer. Carcinogenesis 23: 87-91, 2002.
-
(2002)
Carcinogenesis
, vol.23
, pp. 87-91
-
-
Ebert, M.P.1
Fei, G.2
Kahmann, S.3
-
68
-
-
0036966399
-
Inverse relationship between APC gene mutation in gastric adenomas and development of adenocarcinoma
-
Lee JH, Abraham SC, Kim HS, et al: Inverse relationship between APC gene mutation in gastric adenomas and development of adenocarcinoma. Am J Pathol 161: 611-618, 2002.
-
(2002)
Am J Pathol
, vol.161
, pp. 611-618
-
-
Lee, J.H.1
Abraham, S.C.2
Kim, H.S.3
-
69
-
-
1442310498
-
Focus on gastric cancer
-
Ushijima T and Sasako M: Focus on gastric cancer. Cancer Cell 5: 121-125, 2004.
-
(2004)
Cancer Cell
, vol.5
, pp. 121-125
-
-
Ushijima, T.1
Sasako, M.2
-
70
-
-
34249317261
-
Development of gastric tumors in Apc(Min/+) mice by the activation of the beta-catenin/Tcf signaling pathway
-
Tomita H, Yamada Y, Oyama T, et al: Development of gastric tumors in Apc(Min/+) mice by the activation of the beta-catenin/Tcf signaling pathway. Cancer Res 67: 4079-4087, 2007.
-
(2007)
Cancer Res
, vol.67
, pp. 4079-4087
-
-
Tomita, H.1
Yamada, Y.2
Oyama, T.3
-
71
-
-
10644231009
-
PPARdelta status and Apc-mediated tumourigenesis in the mouse intestine
-
Reed KR, Sansom OJ, Hayes AJ, et al: PPARdelta status and Apc-mediated tumourigenesis in the mouse intestine. Oncogene 23: 8992-8996, 2004.
-
(2004)
Oncogene
, vol.23
, pp. 8992-8996
-
-
Reed, K.R.1
Sansom, O.J.2
Hayes, A.J.3
|