The electricidal effect is active in an experimental model of Staphylococcus epidermidis chronic foreign body osteomyelitis

Antimicrobial Agents and Chemotherapy

Volumn 53, Issue 10, 2009, Pages 4064-4068

  Del Pozo, Jose L ^a   Rouse, Mark S ^a   Euba, Gorane ^a   Kang, Cheol In ^a   Mandrekar, Jayawant N ^a   Steckelberg, James M ^a   Patel, Robin ^a  

^a MAYO CLINIC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DOXYCYCLINE; STAINLESS STEEL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERICIDAL ACTIVITY; BIOFILM; BONE MARROW; CHRONIC DISEASE; COLONY FORMING UNIT; CONTROLLED STUDY; DRUG BLOOD LEVEL; ELECTRIC ACTIVITY; ELECTRIC CURRENT; EXPERIMENTAL MODEL; FOREIGN BODY; IMPLANT; IN VIVO CULTURE; MALE; NONHUMAN; OSTEOMYELITIS; PLANKTON; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RABBIT; STAPHYLOCOCCUS EPIDERMIDIS; STAPHYLOCOCCUS INFECTION; TIBIA; TISSUE CULTURE;

ANIMALS; ANTI-BACTERIAL AGENTS; DISEASE MODELS, ANIMAL; DOXYCYCLINE; ELECTRICITY; FOREIGN BODIES; MALE; MICROBIAL SENSITIVITY TESTS; OSTEOMYELITIS; RABBITS; STAPHYLOCOCCUS EPIDERMIDIS; TIBIA;

EID: 70349313507     PISSN: 00664804     EISSN: 10986596     Source Type: Journal    
DOI: 10.1128/AAC.00432-09     Document Type: Article

References (23)

1. Brighton, C. T., Z. B. Friedenberg, E. I. Mitchell, and R. E. Booth. 1977. Treatment of nonunion with constant direct current. Clin. Orthop. Relat. Res. 124:106-123.
2. Clinical and Laboratory Standards Institute. 2006. M7-A7. Methods for dilution antimicrobial susceptibility test for bacteria that grow aerobically; approved standard, 7th ed. Clinical and Laboratory Standards Institute, Wayne, PA.
3. del Pozo, J. L., and R. Patel. 2007. The challenge of treating biofilm-associated bacterial infections. Clin. Pharmacol. Ther. 82:204-209.
4. del Pozo, J. L., M. S. Rouse, J. N. Mandrekar, M. F. Sampedro, J. M. Steckelberg, and R. Patel. 2009. Effect of electrical current on the activities of antimicrobial agents against Pseudomonas aeruginosa, Staphylococcus aureus, and Staphylococcus epidermidis biofilms. Antimicrob. Agents Chemother. 53:35-40.
5. del Pozo, J. L., M. S. Rouse, J. N. Mandrekar, J. M. Steckelberg, and R. Patel. 2009. The electricidal effect: reduction of Staphylococcus and Pseudomonas biofilms by prolonged exposure to low-intensity electrical current. Antimicrob. Agents Chemother. 53:41-45.
6. del Pozo, J. L., M. S. Rouse, and R. Patel. 2008. Bioelectric effect and bacterial biofilms. A systematic review. Int. J. Artif. Organs 31:786-795.
7. Donlan, R. M. 2001. Biofilm formation: a clinically relevant microbiological process. Clin. Infect. Dis. 33:1387-1392.
8. Dunn, A. W., and G. A. Rush III. 1984. Electrical stimulation in treatment of delayed union and nonunion of fractures and osteotomies. South. Med. J. 77:1530-1534.
9. Evans, R. O., J. A. Goldberg, W. J. Bruce, and W. Walsh. 2004. Reoperated clavicular nonunion treated with osteogenic protein 1 and electrical stimulation. J. Shoulder Elbow Surg. 13:573-575.
10. Liu, W. K., M. R. Brown, and T. S. Elliott. 1997. Mechanisms of the bactericidal activity of low amperage electric current (DC). J. Antimicrob. Chemother. 39:687-695.
11. Patel, R., K. E. Piper, M. S. Rouse, and J. M. Steckelberg. 2000. Linezolid therapy of Staphylococcus aureus experimental osteomyelitis. Antimicrob. Agents Chemother. 44:3438-3440.
12. Percy, D. H., and W. D. Black. 1988. Pharmacokinetics of tetracycline in the domestic rabbit following intravenous or oral administration. Can. J. Vet. Res. 52:5-11.
13. Poortinga, A. T., R. Bos, and H. J. Busscher. 2000. Controlled electrophoretic deposition of bacteria to surfaces for the design of biofilms. Biotechnol. Bioeng. 67:117-120.
14. Rolain, J. M., A. Boulos, M. N. Mallet, and D. Raoult. 2005. Correlation between ratio of serum doxycycline concentration to MIC and rapid decline of antibody levels during treatment of Q. fever endocarditis. Antimicrob. Agents Chemother. 49:2673-2676.
15. Shimada, K., and K. Shimahara. 1985. Leakage of cellular contents and morphological changes in resting Escherichia coli B cells exposed to an alternating changes. Agric. Biol. Chem. 49:3605-3607.
16. Speer, B. S., N. B. Shoemaker, and A. A. Salyers. 1992. Bacterial resistance to tetracycline: mechanisms, transfer, and clinical significance. Clin. Microbiol. Rev. 5:387-399.
17. Srivastava, K. P., and A. K. Saxena. 1977. Fracture healing in a case of nonunion of the tibia by electrical stimulation. Int. Surg. 62:35-36.
18. Stewart, P. S., W. Wattanakaroon, L. Goodrum, S. M. Fortun, and B. R. McLeod. 1999. Electrolytic generation of oxygen partially explains electrical enhancement of tobramycin efficacy against Pseudomonas aeruginosa biofilm. Antimicrob. Agents Chemother. 43:292-296.
19. van der Borden, A. J., P. G. Maathuis, E. Engels, G. Rakhorst, H. C. van der Mei, H. J. Busscher, and P. K. Sharma. 2007. Prevention of pin tract infection in external stainless steel fixator frames using electric current in a goat model. Biomaterials 28:2122-2126.
20. van der Borden, A. J., H. van der Werf, H. C. van der Mei, and H. J. Busscher. 2004. Electric current-induced detachment of Staphylococcus epidermidis biofilms from surgical stainless steel. Appl. Environ. Microbiol. 70:6871-6874.
21. Vuong, C., S. Kocianova, J. Yu, J. L. Kadurugamuwa, and M. Otto. 2008. Development of real-time in vivo imaging of device-related Staphylococcus epidermidis infection in mice and influence of animal immune status on susceptibility to infection. J. Infect. Dis. 198:258-261.
22. Vuong, C., and M. Otto. 2002. Staphylococcus epidermidis infections. Microbes Infect. 4:481-489.
23. Washington, J. A. (ed.). 1985. Laboratory procedures in clinical microbiology. Springer-Verlag, New York, NY.