Epitopes of human leukocyte antigen class I antibodies found in sera of normal healthy males and cord blood

Human Immunology

Volumn 70, Issue 10, 2009, Pages 844-853

  El Awar, Nadim ^a   Terasaki, Paul I ^b   Nguyen, Anh ^a   Sasaki, Nori ^a   Morales Buenrostro, Luis E ^c   Saji, Hiroh ^d   Maruya, Etsuko ^d   Poli, Francesca ^e  

^a One Lambda Inc   (United States)

^b TERASAKI FOUNDATION LABORATORY   (United States)

^c INSTITUTO NACIONAL DE CIENCIAS MÉDICAS Y NUTRICIÓN SALVADOR ZUBIRÁN   (Mexico)

^d Japanese Red Cross Kanto Koshinetsu Block Blood Center   (Japan)

^e FONDAZIONE IRCCS CA GRANDA OSPEDALE MAGGIORE POLICLINICO   (Italy)

Author keywords

Cryptic epitopes; Epitopes of natural HLA antibodies; Exposed epitopes; Recombinant HLA class I antigens; Single antigen

Indexed keywords

EPITOPE; HLA ANTIBODY; HLA ANTIGEN CLASS 1;

ARTICLE; BLOOD SAMPLING; CONTROLLED STUDY; EPITOPE MAPPING; HUMAN; MALE; NORMAL HUMAN; PRIORITY JOURNAL; SENSITIVITY AND SPECIFICITY; UMBILICAL CORD BLOOD;

ANTIBODIES; EPITOPES; FETAL BLOOD; GRAFT REJECTION; HISTOCOMPATIBILITY ANTIGENS CLASS I; HUMANS; ISOANTIBODIES; MALE; PROTEIN CONFORMATION;

EID: 70349312385     PISSN: 01988859     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.humimm.2009.06.020     Document Type: Article

References (15)

1. Morales-Buenrostro L.E., Terasaki P.I., Marino-Vazquez L.A., Lee J.H., El-Awar N., and Alberu J. "Natural" human leukocyte antigen antibodies found in nonalloimmunized healthy males. Transplantation 86 (2008) 1111-1115
2. El-Awar N.R., Akaza T., Terasaki P.I., and Nguyen A. Human leukocyte antigen class I epitopes: update to 103 total epitopes, including the C locus. Transplantation 84 (2007) 532-540
3. Idica A., Sasaki N., Hardy S., and Terasaki P. Unexpected frequencies of HLA antibody specificities in the sera of pre-transplant kidney patients. In: Terasaki P.I. (Ed). Clinical transplants (2006), Terasaki Foundation Laboratory, Los Angeles 161-170
4. Idica A., Sasaki N., Hardy S., and Terasaki P. Unexpected frequencies of HLA antibody specificities present in sera of multitransfused patients. In: Terasaki P.I. (Ed). Clinical transplants (2006), Terasaki Foundation Laboratory, Los Angeles 139-159
5. Pei R., Lee J.H., Shih N.J., Chen M., and Terasaki P.I. Single human leukocyte antigen flow cytometry beads for accurate identification of human leukocyte antigen antibody specificities. Transplantation 75 (2003) 43-49
6. Anthony Nolan Research Institute Web site. http://www.anthonynolan.org.uk/HIG/data.html Accessed May 2003
7. Sheriff S., Silverton E.W., Padlan E.A., Cohen G.H., Smith-Gill S.J., Finzel B.C., et al. Three-dimensional structure of an antibody-antigen complex. Proc Natl Acad Sci USA 84 (1987) 8075-8079
8. Amit A.G., Mariuzza R.A., Phillips S.E., and Poljak R.J. Three-dimensional structure of an antigen-antibody complex at 2.8 A resolution. Science 233 (1986) 747-753
9. National Center for Biotechnology Information Web site. http://www.ncbi.nlm.nih.gov/Structure/CN3D/cn3d.shtml Accessed November 2005
10. National Center for Biotechnology Information Web site. http://www.ncbi.nlm.nih.gov/Structure/mmdb/mmdbsrv.cgi?form_6&db_t&Dopt_s&uid_25415 Accessed November 2005
11. El-Awar N., Lee J.H., Tarsitani C., and Terasaki P.I. HLA Class I epitopes: recognition of binding sites by mAbs or eluted alloantibody confirmed with single recombinant antigens. Hum Immunol 68 (2007) 170-180
12. Tongio M.M., Falkenrodt A., Mitsuishi Y., Urlacher A., Bergerat J.P., North M.L., et al. Natural HLA antibodies. Tissue Antigens 26 (1985) 271-285
13. Collins Z.V., Arnold P.F., Peetoom F., Smith G.S., and Walford R.L. A naturally occurring monospecific anti-HL-A8 isoantibody. Tissue Antigens 3 (1973) 358-363
14. Lepage V., Degos L., and Dausset J. A "natural" anti-HLA-A2 antibody reacting with homozygous cells. Tissue Antigens 8 (1976) 139-142
15. Cai J., Terasaki P.I., Anderson N., Lachmann N., and Schenemann C. Intact HLA not beta 2 m free heavy chain specific HLA class I antibodies are predictive of graft failure. Transplantation 88 (2009) 226-230