High-throughput metal screening in pharmaceutical samples by ICP-MS with automated flow injection using a modified HPLC configuration

Journal of Pharmaceutical and Biomedical Analysis

Volumn 51, Issue 1, 2010, Pages 90-95

  Tu, Qiang ^a   Wang, Tiebang ^a   Welch, Christopher J ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

Analysis; Flow injection; Inductively coupled plasma mass spectrometry (ICP MS); Metal; Pharmaceutical

Indexed keywords

CHROMIUM; DRUG; METAL; PALLADIUM; RHODIUM;

ARTICLE; AUTOMATION; CHEMICAL ANALYSIS; CONTROLLED STUDY; DRUG IMPURITY; FLOW INJECTION ANALYSIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HIGH THROUGHPUT SCREENING; MASS SPECTROMETRY; PRIORITY JOURNAL;

CHEMISTRY, PHARMACEUTICAL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CHROMIUM; DRUG CONTAMINATION; FLOW INJECTION ANALYSIS; MASS SPECTROMETRY; METALS; PALLADIUM; RHODIUM; TIME FACTORS;

EID: 70349312356     PISSN: 07317085     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jpba.2009.08.012     Document Type: Article

References (15)

1. Wang T., Wu J., Hartman R., Jia X., and Egan R. J. Pharm. Biomed. Anal. 23 (2000) 867-890
2. Wang T., Wu J., Jia X., Bu X., Santos I., and Egan R. Pharm. Forum 29 (2003) 1328-1336
3. Lewen N., Mathew S., Schenkenberger M., and Raglione T. J. Pharm. Biomed. Anal. 35 (2004) 739-752
4. Huang J., Hu X., Zhang J., Li K., Yan Y., and Xu X. J. Pharm. Biomed. Anal. 40 (2006) 227-234
5. Rao R.N., and Talluri M.V.N.K. J. Pharm. Biomed. Anal. 43 (2007) 1-13
6. Welch C.J., Shaimi M., Biba M., Chilenski J.R., Szumigala Jr. R.H., Doling U., Mathre D.J., and Reider P.J. J. Sep. Sci. 25 (2002) 847-850
7. Welch C.J., Albaneze-Walker J., Leonard W.R., Biba M., DaSilva J., Henderson D., Laing B., Mathre D.J., Spencer S., Bu X., and Wang T. Org. Process Res. Dev. 9 (2005) 198-205
8. Vázquez A.S., Costa-Fernandez J.M., Encinar J.R., Pereiro R., and Sanz-Medel A. Anal. Chim. Acta 623 (2008) 140-145
9. Stefánka Z., Abrankó L., Dernovics M., and Fodor P. Talanta 63 (2004) 705-712
10. Silva M., Kyser K., and Beauchemin D. Anal. Chim. Acta 584 (2007) 447-454
11. Yourd E.R., Tyson J.F., and Koons R.D. Spectrochim. Acta 56B (2001) 1731-1745
12. Coedo A.G., Padilla I., Dorado T., and Alguacil F.J. Anal. Chim. Acta 389 (1999) 247-255
13. Kahen K., Strubinger A., Chirinos J.R., and Montaser A. Spectrochim. Acta 58B (2003) 397-413
14. Homazava N., Ulrich A., and Krähenbühl U. Spectrochim. Acta 63B (2008) 777-783
15. Tu Q., Wang T., Welch C.J., Wang P., Jia X., Raab C., Bu X., Bykowski D., Hohenstaufen B., and Doyle M.P. Anal. Chem. 78 (2006) 1282-1289