Spinal cord injury research in mice: 2008 Review

TheScientificWorldJournal

Volumn 9, Issue , 2009, Pages 490-498

  Steuer, Inge ^a   Guertin, Pierre A ^a  

^a UNIVERSITÉ LAVAL   (Canada)

Author keywords

Health degradation; Lesion; Neuron; Spinal cord; Transection

Indexed keywords

AQUAPORIN 4; BA 210; BECLIN 1; BRAIN DERIVED NEUROTROPHIC FACTOR; CD11B ANTIGEN; CD45 ANTIGEN; CLONIDINE; CYCLOOXYGENASE 2; GANCICLOVIR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 12; ISOLECTIN B4; LEUKOTRIENE B4; MESSENGER RNA; MILNACIPRAN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MONTELUKAST; NEUROPROTECTIVE AGENT; PROPENTOFYLLINE; PROSTAGLANDIN D2; PROSTAGLANDIN E2; PROTEIN BCL 2; PROTEOCHONDROITIN SULFATE; STAT3 PROTEIN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; WNT PROTEIN; YELLOW FLUORESCENT PROTEIN; ZILEUTON;

ANTIINFLAMMATORY ACTIVITY; APOPTOSIS; ASTROCYTE; ASTROCYTOSIS; AXONAL INJURY; CD3+ T LYMPHOCYTE; CELL DEATH; CELL PROLIFERATION; CHRONIC PAIN; DEGENERATION; DENDRITIC CELL; DRUG EFFECT; DRUG EFFICACY; DRUG SAFETY; LYMPHOCYTOPENIA; MACROPHAGE; MESENCHYMAL STEM CELL TRANSPLANTATION; MOTOR PERFORMANCE; MYELITIS; NERVE CELL; NERVE FIBER REGENERATION; NEURAL STEM CELL; NEUROFILAMENT; NEUTROPHIL; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PERIPHERAL NERVE INJURY; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; REMYELINIZATION; SCAR FORMATION; SEXUAL DYSFUNCTION; SHORT SURVEY; SIGNAL TRANSDUCTION; SPINAL CORD COMPRESSION; SPINAL CORD INJURY; TISSUE INJURY; UPREGULATION; ANIMAL; CONVALESCENCE; DISEASE MODEL; HUMAN; METABOLISM; MOUSE; NERVE CELL NETWORK; NERVE REGENERATION; PATHOPHYSIOLOGY; PHYSIOLOGY; REVIEW;

MURINAE; MUS;

ANIMALS; DISEASE MODELS, ANIMAL; HUMANS; MICE; NERVE NET; NERVE REGENERATION; RECOVERY OF FUNCTION; SPINAL CORD INJURIES;

EID: 70349311417     PISSN: None     EISSN: 1537744X     Source Type: Journal    
DOI: 10.1100/tsw.2009.63     Document Type: Short Survey

References (48)

1. Ziv, Y., Avidan, H., Pluchino, S., Martino, G., and Schwartz, M. (2006) Synergy between immune cells and adult neural stem/progenitor cells promotes functional recovery from spinal cord injury. Proc. Natl. Acad. Sci. U. S. A. 103(35), 13174-13179. (Pubitemid 44338935)
2. Petit, A., Sellers, D.L., Liebl, D.J., Tessier-Lavigne, M., Kennedy, T.E., and Horner, P.J. (2007) Adult spinal cord progenitor cells are repelled by netrin-1 in the embryonic and injured adult spinal cord. Proc. Natl. Acad. Sci. U. S. A. 104(45), 17837-17842. (Pubitemid 350210921)
3. Manet, V., Prieto, M., Privat, A., and Gimenez y Ribotta, M. (2003) Axonal plasticity and functional recovery after spinal cord injury in mice deficient in both glial fibrillary acidic protein and vimentin genes. Proc. Natl. Acad. Sci. U. S. A. 100(15), 8999-9004.
4. Wamil, A.W., Wamil, B.D., and Hellerqvist, C.G. (1998) CM101-mediated recovery of walking ability in adult mice paralyzed by spinal cord injury. Proc. Natl. Acad. Sci. U. S. A. 95(22), 13188-13193.
5. Gosgnach, S., Lanuza, G.M., Butt, S.J., Saueressig, H., Zhang, Y., Velasquez, T., Riethmacher, D., Callaway, E.M., Kiehn, O., and Goulding, M. (2006) V1 spinal neurons regulated the speed of vertebrate locomotor outputs. Nature 440(7081), 215-219. (Pubitemid 43372099)
6. Kullander, K., Butt, S.J., Lebret, J.M., Lundfald, L., Restrepo, C.E., Rydstrom, A., Klein, R., and Kiehn, O. (2003) Role of EphA4 and EphrinB3 in local neuronal circuits that control walking. Science 299(5614), 1889-1892. (Pubitemid 36358203)
7. Guertin, P.A. (2004) Synergistic activation of the central pattern generator for locomotion by l-beta-3,4-dihydrophenylalanine and quipazine in adult paraplegic mice. Neurosci. Lett. 358(2), 71-74.
8. Landry, E.S., Lapointe, N.P., Rouillard, C., Levesque, D., Hedlund, P.B., and Guertin, P.A. (2006) Contribution of spinal 5-HT1A and 5-HT7 receptors to locomotor-like movement induced by 8-H-DPAT in spinal cord-transected mice. Eur. J. Neurosci. 24(2), 535-546. (Pubitemid 44100345)
9. Plemel, J.R., Duncan, G., Chen, K.W., Shannon, C., Park, S., Sparling, J.S., and Tetzlaff, W. (2008) A graded forceps crush spinal cord injury model in mice. J. Neurotrauma 25(4), 350-370.
10. Lu, M., Quan, Z., Liu, B., Jiang, D., Ou, Y., and Zhao, J. (2008) Establishment and assessment of the mouse model for spinal cord injury. Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi 22(8), 933-938.
11. Kanno, H., Ozawa, H., Sekiguchi, A., and Itoi, E. (2009) Spinal cord injury induces upregulation of Beclin 1 and promotes autophagic cell death. Neurobiol. Dis. 33(2), 143-148.
12. Liu, M., Zhao, J., Liang, H., and Bian, X. (2009) Vaccination with dendritic cells pulsed with homogenate protein of spinal cord promotes functional recovery from spinal cord injury in mice. Spinal Cord. 47(5), 360-366.
13. Yaguchi, M., Ohta, S., Toyama, Y., Kawakami, Y., and Toda, M. (2008) Functional recovery after spinal cord injury in mice through activation of microglia and dendritic cells after IL-12 administration. J. Neurosci. Res. 86(9), 1972-1980.
14. Stirling, D.P. and Yong, V.W. (2008) Dynamics of the inflammatory response after murine spinal cord injury revealed by flow cytometry. J. Neurosci. Res. 86(9), 1944-1958.
15. Saadoun, S., Bell, B.A., Verkman, A.S., and Papadopoulos, M.C. (2008) Greatly improved neurological outcome after spinal cord compression injury in AQP4-deficient mice. Brain 131(Pt 4), 1087-1098.
16. Benton, R.L., Maddie, M.A., Minnillo, D.R., Hagg, T., and Whittemore, S.R. (2008) Griffonia simplicifolia isolectin B4 identifies a specific subpopulation of angiogenic blood vessels following contusive spinal cord injury in the adult mouse. J. Comp. Neurol. 507(1), 1031-1052. (Pubitemid 351214227)
17. Genovese, T., Rossi, A., Mazzon, E., Di Paola, R., Muià, C., Caminiti, R., Bramanti, P., Sautebin, L., and Cuzzocrea, S. (2008a) Effects of zileuton and montelukast in mouse experimental spinal cord injury. Br. J. Pharmacol. 153(3), 568-582. (Pubitemid 351199011)
18. Genovese, T., Esposito, E., Mazzon, E., Di Paola, R., Meli, R., Caminiti, R., Bramanti, P., Fink, M.P., and Cuzzocrea, S. (2008b) Beneficial effects of ethyl pyruvate in a mouse model of spinal cord injury. Shock. [Epub ahead of print]
19. Galvan, M.D., Luchetti, S., Burgos, A.M., Nguyen, H.X., Hooshmand, M.J., Hamers, F.P., and Anderson, A.J. (2008) Deficiency in complement C1q improves histological and functional locomotor outcome after spinal cord injury. J. Neurosci. 28(51), 13876-13888.
20. Hsu, J.Y., Bourguignon, L.Y., Adams, C.M., Peyrollier, K., Zhang, H., Fandel, T., Cun, C.L., Werb, Z., and Noble-Haeusslein, L.J. (2008) Matrix metalloproteinase-9 facilitates glial scar formation in the injured spinal cord. J. Neurosci. 28(50), 13467-13477.
21. Lord-Fontaine, S., Yang, F., Diep, Q., Dergham, P., Munzer, S., Tremblay, P., and McKerracher, L. (2008) Local inhibition of Rho signaling by cell-permeable recombinant protein BA-210 prevents secondary damage and promotes functional recovery following acute spinal cord injury. J. Neurotrauma 25(11), 1309-1322.
22. Kostyk, S.K., Popovich, P.G., Stokes, B.T., Wei, P., and Jakeman, L.B. (2008) Robust axonal growth and a blunted macrophage response are associated with impaired functional recovery after spinal cord injury in the MRL/MpJ mouse. Neuroscience 156(3), 498-514.
23. Herrmann, J.E., Imura, T., Song, B., Qi, J., Ao, Y., Nguyen, T.K., Korsak, R.A., Takeda, K., Akira, S., and Sofroniew, M.V. (2008) STAT3 is a critical regulator of astrogliosis and scar formation after spinal cord injury. J. Neurosci. 28(28), 7231-7243.
24. Kerr, B.J., Girolami, E.I., Ghasemlou, N., Jeong, S.Y., and David, S. (2008) The protective effects of 15-deoxy-delta-(12,14)-prostaglandin J2 in spinal cord injury. Glia 56(4), 436-448. (Pubitemid 351212952)
25. Barrette, B., Hébert, M.A., Filali, M., Lafortune, K., Vallières, N., Gowing, G., Julien, J.P., and Lacroix, S. (2008) Requirement of myeloid cells for axon regeneration. J. Neurosci. 28(38), 9363-9376.
26. Lasiene, J., Shupe, L., Perlmutter, S., and Horner, P. (2008) No evidence for chronic demyelination in spared axons after spinal cord injury in a mouse. J. Neurosci. 28(15), 3887-3896.
27. Oschipok, L.W., The, J., McPhail, L.T., and Tetzlaff, W. (2008) Expression of Semaphorin3C in axotomized rodent facial and rubrospinal neurons. Neurosci. Lett. 434(1), 113-118.
28. Lytle, J.M., Chittajallu, R., Wrathall, J.R., and Gallo, V. (2009) NG2 cell response in the CNP-EGFP mouse after contusive spinal cord injury. Glia 57(3), 270-285.
29. Rolls, A., Shechter, R., London, A., Segev, Y., Jacob-Hirsch, J., Amariglio, N., Rechavi, G., and Schwartz, M. (2008) Two faces of chondroitin sulfate proteoglycan in spinal cord repair: a role in microglia/macrophage activation. PLoS Med. 5(8), e171.
30. White, R.E., Yin, F.Q., and Jakeman, L.B. (2008) TGF-alpha increases astrocyte invasion and promotes axonal growth into the lesion following spinal cord injury in mice. Exp. Neurol. [Epub ahead of print]
31. Carter, L.M., Starkey, M.L., Akrimi, S.F., Davies, M., McMahon, S.B., and Bradbury, E.J. (2008) The yellow fluorescent protein (YFP-H) mouse reveals neuroprotection as a novel mechanisms underlying chondroitinase ABC-mediated repair after spinal cord injury. J. Neurosci. 28(52), 14107-14120.
32. Liu, Y., Wang, X., Lu, C.C., Kerman, R., Steward, O., Xu, X.M., and Zou, Y. (2008) Repulsive Wnt signaling inhibits axon regeneration after CNS injury. J. Neurosci. 28(33), 8376-8382.
33. Meletis, K., Barnabé-Heider, F., Carlén, M., Evergren, E., Tomilin, N., Shupliakov, O., and Frisén, J. (2008) Spinal cord injury reveals multilineage differentiation of ependymal cells. PLoS Biol 6(7), e182.
34. Alexanian, A.R., Maiman, D.J., Kurpad, S.N., and Gennarelli, T.A. (2008) In vitro and in vivo characterization of neurally modified mesenchymal stem cells induced by epigenetic modifiers and neural stem cell environment. Stem Cells Dev. 17(6), 1123-1130.
35. Bretzner, F., Liu, J., Currie, E., Roskams, A.J., and Tetzlaff, W. (2008) Undesired effects of a combinatorial treatment for spinal cord injury--transplantation of olfactory ensheathing cells and BDNF infusion to the red nucleus. Eur. J. Neurosci. 28(9), 1795-1807.
36. Courtine, G., Song, B., Roy, R.R., Zhong, H., Herrmann, J.E., Ao, Y., Qi, J., Edgerton, V.R., and Sofroniew, M.V. (2008) Recovery of supraspinal control of stepping via indirect propriospinal relay connections after spinal cord injury. Nat. Med. 14(1), 69-74.
37. Steward, O., Sharp, K., Yee, K.M., and Hofstadter, M. (2008) A re-assessment of the effects of a Nogo-66 receptor antagonist on regenerative growth of axons and locomotor recovery after spinal cord injury in mice. Exp. Neurol. 209(2), 446-468.
38. Ung, R.V., Lapointe, N.P., and Guertin, P.A. (2008) Early adaptive changes in chronic paraplegic mice: a model to study rapid health degradation after spinal cord injury. Spinal Cord 46(3), 176-180.
39. Picard, S., Lapointe, N.P., Brown, J.P., and Guertin, P.A. (2008) Histomorphometric and densitometric changes in the femora of spinal cord transected mice. Anat. Rec. (Hoboken) 291(3), 303-307.
40. Rezaian, J., Movahedin, M., and Mowla, S.J. (2009) CatSper genes expression, semen characteristics and histology of testes in the contusive spinal cord-injured mice model. Spinal Cord 47(1), 76-81.
41. Tawfik, V.L., Regan, M.R., Haenggeli, C., Lacroix-Fralish, M.L., Nutile-McMenemy, N., Perez, N., Rothstein, J.D., and DeLeo, J.A. (2008) Propentofylline-induced astrocyte modulation leads to alterations in glial glutamate promoter activation following spinal nerve transection. Neuroscience 152(4), 1086-1092.
42. Suzuki, T., Ueta, K., Tamagaki, S., and Mashimo, T. (2008) Antiallodynic and antihyperalgesic effect of milnacipran in mice with spinal nerve ligation. Anesth. Analg. 106(4), 1309-1315.
43. Christoph, T., Bahrenberg, G., De Vry, J., Englberger, W., Erdmann, V.A., Frech, M., Kögel, B., Röhl, T., Schiene, K., Schröder, W., Seibler, J., and Kurreck, J. (2008) Investigation of TRPV1 loss-of-function phenotypes in transgenic shRNA expressing and knockout mice. Mol. Cell. Neurosci. 37(3), 579-589.
44. Martucci, C., Trovato, A.E., Costa, B., Borsani, E., Franchi, S., Magnaghi, V., Panerai, A.E., Rodella, L.F., Valsecchi, A.E., Sacerdote, P., and Colleoni, M. (2008) The purinergic antagonist PPADS reduces pain related behaviours and interleukin-1beta, interleukin-6, iNOS and nNOS overproduction in central and peripheral nervous system after peripheral neuropathy in mice. Pain 137(1), 81-95.
45. Lapointe, N.P., Ung, R.V., Rouleau, P., and Guertin, P.A. (2008a) Effects of spinal alpha(2)-adrenoceptor and I(1)- imidazoline receptor activation on hindlimb movement induction in spinal cord-injured mice. J. Pharmacol. Exp. Ther. 325(3), 994-1006. (Pubitemid 351724307)
46. Lapointe, N.P., Ung, R.V., Rouleau, P., and Guertin, P.A. (2008b) Tail pinching-induced hindlimb movements are suppressed by clonidine in spinal cord injured mice. Behav. Neurosci. 122(3), 576-588. (Pubitemid 351787836)
47. Lapointe, N.P. and Guertin, P.A. (2008) Synergistic effects of D1/5 and 5-HT1A/7 receptor agonists on locomotor movement induction in complete spinal cord-transected mice. J. Neurophysiol. 100(1), 160-168.
48. Ung, R.V., Landry, E.S., Lapointe, N.P., Rouillard, C., and Guertin, P.A. (2009) Role of spinal 5-HT2 receptor subtypes in quipazine-induced hindlimb movements after a low-thoracic spinal cord transection. Eur. J. Neurosci. 28(11), 2231-2242.