A bone marrow F-18 FDG uptake exceeding the liver uptake may indicate bone marrow hyperactivity

Annals of Nuclear Medicine

Volumn 23, Issue 7, 2009, Pages 643-649

  Inoue, Kentaro ^a   Goto, Ryoi ^a   Okada, Ken ^a   Kinomura, Shigeo ^a   Fukuda, Hiroshi ^a  

^a TOHOKU UNIVERSITY   (Japan)

Author keywords

Age; Bone marrow; C reactive protein; F 18 FDG; Inflammation

Indexed keywords

C REACTIVE PROTEIN; FLUORODEOXYGLUCOSE F 18;

ADRENAL CORTEX ADENOMA; ADULT; ARTICLE; BENIGN TUMOR; BONE CANCER; BONE MARROW; BONE SCINTISCANNING; CHRONIC PANCREATITIS; COLON CANCER; COMPUTED TOMOGRAPHY SCANNER; COMPUTER ASSISTED EMISSION TOMOGRAPHY; COMPUTER ASSISTED TOMOGRAPHY; CONTROL GROUP; CONTROLLED STUDY; CORRELATION COEFFICIENT; CREUTZFELDT JAKOB DISEASE; ESOPHAGUS CANCER; FEVER; GINGIVITIS; HEAD AND NECK CANCER; HUMAN; LIVER; LIVER CANCER; LUMBAR VERTEBRA; LUNG INFECTION; LUNG NON SMALL CELL CANCER; LYMPHOMA; MAJOR CLINICAL STUDY; MULTIPLE REGRESSION; NUCLEAR MAGNETIC RESONANCE IMAGING; PANCREAS ISLET CELL CARCINOMA; PANNICULITIS; PELVIS ABSCESS; PLEURISY; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; RADIOGRAPHY; RETROSPECTIVE STUDY; SARCOIDOSIS; THORAX; TONSILLITIS; VASCULAR DISEASE; VASCULITIS;

AGE FACTORS; BONE MARROW; FLUORODEOXYGLUCOSE F18; HEMATOLOGY; HUMANS; INFLAMMATION; LIVER; MIDDLE AGED; NEOPLASMS; REGRESSION ANALYSIS; RETROSPECTIVE STUDIES;

EID: 70349309657     PISSN: 09147187     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12149-009-0286-9     Document Type: Article

References (29)

1. BA Gordon FL Flanagan F Dehdashti 1997 Whole-body positron emission tomography: normal variations, pitfalls, and technical considerations AJR Am J Roentgenol 169 1675 1680
2. S Prevost L Boucher P Larivee R Boileau F Benard 2006 Bone marrow hypermetabolism on 18F-FDG PET as a survival prognostic factor in non-small cell lung cancer J Nucl Med 47 559 565
3. F Cicone D Loose P Deron H Vermeersch A Signore F Van de Vyvere 2008 Prognostic value of FDG uptake by the bone marrow in squamous cell carcinoma of the head and neck Nucl Med Commun 29 431 435
4. C Van de Wiele F VandeVyver C Debruyne J Philippe JP van Meerbeeck 2008 FDG uptake by the bone marrow in NSCLC patients is related to TGF-beta but not to VEGF or G-CSF serum levels Eur J Nucl Med Mol Imaging 35 519 522
5. C Fan M Hernandez-Pampaloni M Houseni W Chamroonrat S Basu R Kumar 2007 Age-related changes in the metabolic activity and distribution of the red marrow as demonstrated by 2-deoxy-2-[F-18]fluoro-D-glucose positron emission tomography Mol Imaging Biol 9 300 307
6. Y Murata K Kubota M Yukihiro K Ito H Watanabe H Shibuya 2006 Correlations between 18F-FDG uptake by bone marrow and hematological parameters: measurements by PET/CT Nucl Med Biol 33 999 1004
7. CD Ramos YE Erdi M Gonen E Riedel HW Yeung HA Macapinlac 2001 FDG-PET standardized uptake values in normal anatomical structures using iterative reconstruction segmented attenuation correction and filtered back-projection Eur J Nucl Med 28 155 164
8. Y Sugawara SJ Fisher KR Zasadny PV Kison LH Baker RL Wahl 1998 Preclinical and clinical studies of bone marrow uptake of fluorine-1- fluorodeoxyglucose with or without granulocyte colony-stimulating factor during chemotherapy J Clin Oncol 16 173 180
9. JA Thie 2004 Understanding the standardized uptake value, its methods, and implications for usage J Nucl Med 45 1431 1434
10. P Iozzo F Geisler V Oikonen M Maki T Takala O Solin 2003 Insulin stimulates liver glucose uptake in humans: an 18F-FDG PET Study J Nucl Med 44 682 689
11. Chin BB, Green ED, Turkington TG, Hawk TC, Coleman RE. Increasing uptake time in FDG-PET: standardized uptake values in normal tissues at 1 versus 3 h. Mol Imaging Biol. 2009; 11(2):118-22
12. C Ricci M Cova YS Kang A Yang A Rahmouni WW Scott Jr 1990 Normal age-related patterns of cellular and fatty bone marrow distribution in the axial skeleton: MR imaging study Radiology 177 83 88
13. TM Blodgett JT Ames FS Torok BM McCook CC Meltzer 2004 Diffuse bone marrow uptake on whole-body F-18 fluorodeoxyglucose positron emission tomography in a patient taking recombinant erythropoietin Clin Nucl Med 29 161 163
14. A Plantade F Montravers F Selle V Izrael JN Talbot 2003 Diffusely increased F-18 FDG uptake in bone marrow in a patient with acute anemia and recent erythropoietin therapy Clin Nucl Med 28 771 772
15. PC Kao SC Shiesh TJ Wu 2006 Serum C-reactive protein as a marker for wellness assessment Ann Clin Lab Sci 36 163 169
16. S Yamada T Gotoh Y Nakashima K Kayaba S Ishikawa N Nago 2001 Distribution of serum C-reactive protein and its association with atherosclerotic risk factors in a Japanese population : Jichi Medical School Cohort Study Am J Epidemiol 153 1183 1190
17. AM Mauer JW Athens H Ashenbrucker GE Cartwright MM Wintrobe 1960 Leukokinetic studies. II. A method for labeling granulocytes in vitro with radioactive diisopropylfluorophosphate (DFP) J Clin Invest 39 1481 1486
18. DM Vigushin MB Pepys PN Hawkins 1993 Metabolic and scintigraphic studies of radioiodinated human C-reactive protein in health and disease J Clin Invest 91 1351 1357
19. SB Chiang A Rebenstock L Guan A Alavi H Zhuang 2003 Diffuse bone marrow involvement of Hodgkin lymphoma mimics hematopoietic cytokine-mediated FDG uptake on FDG PET imaging Clin Nucl Med 28 674 676
20. CR Lewanski GR Kaplan J Potter P Richman RF Ashford WL Wong 1999 Bone marrow involvement in breast cancer detected by positron emission tomography J R Soc Med 92 193 195
21. N Seshadri P Wright KK Balan 2007 Rhabdomyosarcoma with widespread bone marrow infiltration: beneficial management role of F-18 FDG PET Clin Nucl Med 32 787 789
22. EF Hollinger H Alibazoglu A Ali A Green G Lamonica 1998 Hematopoietic cytokine-mediated FDG uptake simulates the appearance of diffuse metastatic disease on whole-body PET imaging Clin Nucl Med 23 93 98
23. WJ Yao CK Hoh RA Hawkins JA Glaspy JA Weil SJ Lee 1995 Quantitative PET imaging of bone marrow glucose metabolic response to hematopoietic cytokines J Nucl Med 36 794 799
24. M Morooka K Kubota Y Murata H Shibuya K Ito M Mochizuki 2008 (18)F-FDG-PET/CT findings of granulocyte colony-stimulating factor (G-CSF)-producing lung tumors Ann Nucl Med 22 635 639
25. S Takahashi K Kuwabara M Sawafuji S Akiduki A Ishizaka 2008 F-18 FDG PET imaging in a patient with granulocyte colony-stimulating factor producing pulmonary pleomorphic carcinoma Clin Nucl Med 33 555 557
26. RL Elstrom DE Tsai JA Vergilio LH Downs A Alavi SJ Schuster 2004 Enhanced marrow [18F]fluorodeoxyglucose uptake related to myeloid hyperplasia in Hodgkin's lymphoma can simulate lymphoma involvement in marrow Clin Lymphoma 5 62 64
27. SC Burrell AJ Fischman 2005 Myelofibrosis on F-18 FDG PET imaging Clin Nucl Med 30 674
28. K Inoue K Okada H Harigae Y Taki R Goto S Kinomura 2006 Diffuse bone marrow uptake on F-18 FDG PET in patients with myelodysplastic syndromes Clin Nucl Med 31 721 723
29. A Takalkar JQ Yu R Kumar Y Xiu A Alavi H Zhuang 2004 Diffuse bone marrow accumulation of FDG in a patient with chronic myeloid leukemia mimics hematopoietic cytokine-mediated FDG uptake on positron emission tomography Clin Nucl Med 29 637 639