Analgesic effect from ibuprofen nanoparticles inhaled by male mice

Journal of Aerosol Medicine and Pulmonary Drug Delivery

Volumn 22, Issue 3, 2009, Pages 245-253

  Onischuk, Andrei A ^a   Tolstikova, Tatyana G ^b   Sorokina, Irina V ^b   Zhukova, Natalya A ^b   Baklanov, Anatoly M ^a   Karasev, Vladimir V ^a   Borovkova, Olga V ^a   Dultseva, Galina G ^a   Boldyrev, Vladimir V ^c,d   Fomin, Vasilii M ^e  

^a INSTITUTE OF CHEMICAL KINETICS AND COMBUSTION   (Russian Federation)

^b N N VOROZHTSOV NOVOSIBIRSK INSTITUTE OF ORGANIC CHEMISTRY   (Russian Federation)

^c NOVOSIBIRSK STATE UNIVERSITY   (Russian Federation)

^d INSTITUTE OF SOLID STATE CHEMISTRY AND MECHANOCHEMISTRY   (Russian Federation)

^e KHRISTIANOVICH INSTITUTE OF THEORETICAL AND APPLIED MECHANICS   (Russian Federation)

Author keywords

Aerosol drug administration; Analgesic effect; Ibuprofen; Mice; Nanoparticles; Particle lung deposition

Indexed keywords

IBUPROFEN;

AEROSOL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CHEMICAL COMPOSITION; DRUG ACTIVITY; DRUG DELIVERY SYSTEM; DRUG EFFECT; MALE; MOUSE; NONHUMAN; ULTRAVIOLET SPECTROSCOPY; X RAY DIFFRACTION;

ADMINISTRATION, INHALATION; ANALGESICS, NON-NARCOTIC; ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; IBUPROFEN; LUNG; MALE; MICE; NANOPARTICLES; PARTICLE SIZE;

EID: 70349279195     PISSN: 19412711     EISSN: 19412703     Source Type: Journal    
DOI: 10.1089/jamp.2008.0721     Document Type: Article

References (17)

1. Hickey AJ (ed): Pharmaceutical Inhalation Aerosol Technology, Marcel Dekker, Inc., New York, 2004.
2. Onischuk AA, Tolstikova TG, Sorokina IV, Zhukova NA, Baklanov AM, Karasev VV, Dultseva GG, Boldyrev VV, and Fomin VM. Anti-inflammatory effect from indomethacin nanoparticles inhaled by male mice. J Aerosol Med. 2008; 21:231-244.
3. Meade EA, Smith WL, and DeWitt DL: Differential inhibition of prostaglandin endoperoxide synthase (cyclooxyge-nase) isozymes by aspirin and other nonsteroidal antiinflammatory drugs. J Biol Chem. 1993;268:6610-6614.
4. Kirsh AA, Stechkina IB, and Fuchs NA: Efficiency of aerosol filters made of ultrafine polydisperse fibres. J Aerosol Sci. 1975;5:119-124.
5. Ankilov A, Baklanov A, Colhoun M, Enderle K-H, Gras J, Junlanov Yu, Kaller D, Lindner A, Lushnikov A, Mavliev R, McGovern F, Mirme A, O'Connor TC, Podzimek J, Preining O, Reischl GP, Rudolf R, Sem GJ, Szymanski WW, Tamm E, Vrtala AE, Wagner PE, Winklmayr W, and Zagaynov V: In-tercomparison of number concentration measurements by various aerosol particle counters. Atmos Res. 2002;62:177-207.
6. Koster R, Anderson M, and Deber EI: Acetic acid for anal-getic screening. Fed Proc. 1959;18:412-414.
7. Nada AH, Al-Saidan SM, and Mueller BW: Crystal modification for improving physical and chemical properties of ibuprofen. Pharm Technol. 2005;29:90-101.
8. Hermsdorf D, Jauer S, and Signorell R: Formation and stabilization of ibuprofen nanoparticles by pulsed rapid expansion of supercritical solutions. Mol Phys. 2007;105:951-959.
9. Lee T, Chen YH, and Wang YW: Effects of homochiral molecules of (S)-( )-ibuprofen and (S)-( )-sodium ibuprofen di-hydrate on the crystallization kinetics of racemic (R,S)-(()sodium ibuprofen dihydrate. Crystal Growth Design. 2008;8: 415-426.
10. Stahly GP, Mckenzie AT, Andres MC, Russell CA, Byrn SR, and Johnson P: Determination of the optical purity of ibuprofen using X-ray powder diffraction. J Pharmaceut Sci. 1997;86:970-971.
11. Currie WC, van Schaik S, Vargas I, and Enhorning G: Breathing and pulmonary surfactant function in mice 24 h after ozone exposure. Eur Respir J. 1998;12:288-293. (Pubitemid 28389520)
12. Schaper M, and Brost MA: Respiratory effects of trimellitic anhydride aerosols in mice. Arch Toxicol. 1991;65:671-677.
13. Hamelmann E, Schwarze J, Takeda K, Oshiba A, Larsen GL, Irvin CG, and Gelfand EW: Noninvasive measurement of airway responsiveness in allergic mice using barometric plethysmography. Am J Respir Crit Care Med. 1997;156:766-775
14. Vijayaraghavan R: Modifications of breathing pattern induced by inhaled sulphur mustard in mice. Arch Toxicol. 1997;71:157-164.
15. Fairchild GA: Measurement of respiratory volume for virus retention studies in mice. Appl Microbiol. 1972;24:812-818.
16. Wong BA: Inhalation exposure systems: Design, methods and operation. Toxicol Pathol. 2007;35:3-14.
17. Mutschler E, Derendorf H: Drug Actions. Basic Principles and Therapeutic Aspects. MEDPHARM, Stuttgart, p. 170-171, 1995.