Improvement of impaired calcium and skeletal homeostasis in vitamin D receptor knockout mice by a high dose of calcitriol and maxacalcitol

Bone

Volumn 45, Issue 5, 2009, Pages 964-971

  Shiizaki, Kazuhiro ^a   Hatamura, Ikuji ^b   Imazeki, Ikuo ^c   Moriguchi, Yoshiyuki ^c   Sakaguchi, Toshifumi ^d   Saji, Fumie ^d   Nakazawa, Eiko ^a   Kato, Shigeaki ^e   Akizawa, Tadao ^f   Kusano, Eiji ^a  

^a JICHI MEDICAL UNIVERSITY   (Japan)

^b KANSAI UNIVERSITY OF HEALTH SCIENCES   (Japan)

^c CHUGAI PHARMACEUTICAL CO LTD   (Japan)

^d WAKAYAMA MEDICAL UNIVERSITY   (Japan)

^e UNIVERSITY OF TOKYO   (Japan)

^f SHOWA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Bone histomorphometry; Knock out; Rickets; Signaling pathway; Vitamin D receptor

Indexed keywords

22 OXACALCITRIOL; BIOLOGICAL MARKER; CALBINDIN; CALCEIN; CALCITRIOL; CALCIUM ION; MESSENGER RNA; PARATHYROID HORMONE; VITAMIN D RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE GROWTH; BONE METABOLISM; CALCIUM BLOOD LEVEL; CALCIUM HOMEOSTASIS; CALCIUM TRANSPORT; CANCELLOUS BONE; CONTROLLED STUDY; CORTICAL BONE; DRUG MEGADOSE; DUODENUM; GROWTH PLATE; KNOCKOUT MOUSE; MORPHOMETRICS; MOUSE; NONHUMAN; OSTEOID; PARATHYROID HORMONE BLOOD LEVEL; PROTEIN EXPRESSION; SECONDARY HYPERPARATHYROIDISM; SIGNAL TRANSDUCTION; SMALL INTESTINE; TIBIA; UPREGULATION; UREMIA; WEANING;

ANIMALS; BIOLOGICAL TRANSPORT; BONE AND BONES; CALCITRIOL; CALCIUM; CALCIUM CHANNELS; CALCIUM-BINDING PROTEIN, VITAMIN D-DEPENDENT; DOSE-RESPONSE RELATIONSHIP, DRUG; DUODENUM; GENE EXPRESSION REGULATION; GROWTH PLATE; HOMEOSTASIS; MICE; MICE, KNOCKOUT; OSTEOGENESIS; RECEPTORS, CALCITRIOL; RNA, MESSENGER; TRPV CATION CHANNELS;

EID: 70349276695     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bone.2009.07.013     Document Type: Article

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