Gradient HPLC-DAD for the simultaneous determination of five flavonoids in plasma after intravenously administrated ginkgo biloba extract and its application in the study of pharmacokinetics in rats

Journal of Liquid Chromatography and Related Technologies

Volumn 32, Issue 14, 2009, Pages 2065-2079

  Tang, Dao Quan ^a,b,c   Yin, Xiao Xing ^c   Zhang, Zun Jian ^a,b   Gao, Yuan Yuan ^c   Wei, Ya Qin ^c   Chen, Yong Gang ^c   Han, Lin ^c  

^a BEIJING UNIVERSITY OF POSTS AND TELECOMMUNICATIONS   (China)

^b CHINA PHARMACEUTICAL UNIVERSITY   (China)

^c XUZHOU MEDICAL UNIVERSITY   (China)

Author keywords

Ginkgo biloba extract; High performance liquid chromatography; Isorhamnetin; Kaempferol; Pharmacokinetic; Quercetin; Quercitrin; Rutin

Indexed keywords

GINKGO BILOBA EXTRACT; ISORHAMNETIN; KAEMPFEROL; QUERCETIN; QUERCITRIN; RUTIN;

CHROMATOGRAPHIC ANALYSIS; CHROMATOGRAPHY; FATTY ACIDS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HIGH PRESSURE LIQUID CHROMATOGRAPHY; LIQUIDS; METHANOL; ORGANIC ACIDS; PHARMACOKINETICS; PHENOLS; PLASMA (HUMAN); PLASMAS;

SOLVENT EXTRACTION;

FLAVONOID; FORMIC ACID; GINKGO BILOBA EXTRACT; ISORAHAMNETIN; KAEMPFEROL; METHANOL; QUERCETIN; QUERCITRIN; RUTOSIDE; UNCLASSIFIED DRUG;

ACCURACY; ANALYTICAL EQUIPMENT; ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; BLOOD SAMPLING; COLUMN CHROMATOGRAPHY; CORRELATION COEFFICIENT; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG DETERMINATION; DRUG DISTRIBUTION; DRUG RETENTION; DRUG STABILITY; DRUG STORAGE; DRUG STRUCTURE; ELUTION; FLOW RATE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MALE; NONHUMAN; RAT; SENSITIVITY AND SPECIFICITY; SEPARATION TECHNIQUE; SINGLE DRUG DOSE; VALIDATION STUDY;

GINKGO BILOBA; RATTUS;

EID: 70349275471     PISSN: 10826076     EISSN: 1520572X     Source Type: Journal    
DOI: 10.1080/10826070903126948     Document Type: Article

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