Selective detection of phosphatidylethanol homologues in blood as biomarkers for alcohol consumption by LC-ESI-MS/MS

Journal of Mass Spectrometry

Volumn 44, Issue 9, 2009, Pages 1293-1299

  Gnann, H ^a   Weinmann, W ^a   Engelmann, C ^a   Wurst, F M ^b   Skopp, G ^c   Winkler, M ^d   Thierauf, A ^a   Auwarter V ^a   Dresen, S ^a   Ferreiros Bouzas N ^a  

^a UNIVERSITY OF FREIBURG   (Germany)

^b UNIVERSITY OF SALZBURG   (Austria)

^c UNIVERSITY HOSPITAL HEIDELBERG   (Germany)

^d UNIVERSITY OF ULM   (Germany)

Author keywords

Alcohol; Biomarker; LC MS MS; Phosphatidylethanol; Quantitation

Indexed keywords

ALCOHOL CONSUMPTION; DAILY INTAKE; ETHYL GLUCURONIDE; ETHYL SULFATE; EVAPORATIVE LIGHT SCATTERING DETECTION; INTERNAL STANDARDS; LC-ESI-MS/MS; LC-MS/MS; LIMIT OF DETECTION; LOW CONCENTRATIONS; LOWER FREQUENCIES; PHOSPHATIDYLETHANOL; QUANTITATION; REVERSED PHASE CHROMATOGRAPHY; SELECTIVE DETECTION; VALIDATED METHODS; WHOLE BLOOD;

BLOOD; CHROMATOGRAPHIC ANALYSIS; CHROMATOGRAPHY; ETHANOL; FATTY ACIDS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HIGH PRESSURE LIQUID CHROMATOGRAPHY; ORGANIC SOLVENTS; PHOSPHOLIPIDS; SOLVENT EXTRACTION;

BIOMARKERS;

ALCOHOL; ETHYL GLUCURONIDE; FATTY ACID; ORGANIC SOLVENT; PHOSPHATIDYLBUTANOL; PHOSPHATIDYLETHANOL; PHOSPHOLIPID; UNCLASSIFIED DRUG;

ALCOHOL BLOOD LEVEL; ALCOHOL CONSUMPTION; ARTICLE; AUTOPSY; BLOOD SAMPLING; ELECTROSPRAY MASS SPECTROMETRY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; LIGHT SCATTERING; LIQUID CHROMATOGRAPHY; PRIORITY JOURNAL; REVERSED PHASE LIQUID CHROMATOGRAPHY; SOLVENT EXTRACTION;

ALCOHOL DRINKING; ANALYTIC SAMPLE PREPARATION METHODS; BIOLOGICAL MARKERS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; ETHANOL; FATTY ACIDS; GLYCEROPHOSPHOLIPIDS; HUMANS; MICROCHEMISTRY; MOLECULAR STRUCTURE; REPRODUCIBILITY OF RESULTS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; SUBSTANCE ABUSE DETECTION; TANDEM MASS SPECTROMETRY;

EID: 70349270646     PISSN: 10765174     EISSN: 10969888     Source Type: Journal    
DOI: 10.1002/jms.1608     Document Type: Article

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