Mutation of p107 exacerbates the consequences of Rb loss in embryonic tissues and causes cardiac and blood vessel defects

Proceedings of the National Academy of Sciences of the United States of America

Volumn 106, Issue 35, 2009, Pages 14932-14936

  Berman, Seth D ^a   West, Julie C ^a   Danielian, Paul S ^a   Caron, Alicia M ^a   Stone, James R ^b   Lees, Jacqueline A ^a  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

Cell cycle; Heart; p107; Retinoblastoma

Indexed keywords

PROTEIN P107; RETINOBLASTOMA PROTEIN;

ALLELE; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BLOOD VESSEL; CELL CYCLE; CONGENITAL HEART MALFORMATION; CONTROLLED STUDY; EMBRYO; EMBRYO DEVELOPMENT; EMBRYONAL TISSUE; ENDOTHELIUM CELL; FEMALE; GENE MUTATION; GESTATION PERIOD; HEART MUSCLE CELL; IMMUNOHISTOCHEMISTRY; LENS; MALE; MESENCHYME CELL; MOUSE; NONHUMAN; PERIPHERAL NERVOUS SYSTEM; PHENOTYPE; PLACENTA INSUFFICIENCY; PRIORITY JOURNAL; PROTEIN FAMILY;

ANIMALS; APOPTOSIS; CELL PROLIFERATION; CENTRAL NERVOUS SYSTEM; EMBRYO, MAMMALIAN; FEMALE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HEART DISEASES; LENS, CRYSTALLINE; MALE; MICE; MUTATION; RETINOBLASTOMA PROTEIN; RETINOBLASTOMA-LIKE PROTEIN P107;

MURINAE;

EID: 70349269164     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0902408106     Document Type: Article

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