Fatal lactic acidosis after prolonged linezolid exposure for treatment of multidrug-resistant tuberculosis

European Journal of Internal Medicine

Volumn 20, Issue 6, 2009, Pages

  Boutoille, David ^a   Grossi, Olivier ^a   Depatureaux, Agnes ^b   Tattevin, Pierre ^b  

^a HÔTEL DIEU   (France)

^b PONTCHAILLOU UNIVERSITY HOSPITAL   (France)

Author keywords

[No Author keywords available]

Indexed keywords

AMIKACIN; AMINOSALICYLIC ACID; BICARBONATE; CAPREOMYCIN; CYCLOSERINE; ETHAMBUTOL; ETHIONAMIDE; ISONIAZID; LACTIC ACID; LINEZOLID; MOXIFLOXACIN; PYRAZINAMIDE; RIFAMPICIN;

ABDOMINAL PAIN; ADULT; ANTIBIOTIC RESISTANCE; ARTICLE; BLOOD PH; CASE REPORT; DRUG FATALITY; DRUG SAFETY; DRUG WITHDRAWAL; DYSPNEA; HEARING LOSS; HUMAN; LACTIC ACIDOSIS; LUNG TUBERCULOSIS; MALE; MULTIDRUG RESISTANT TUBERCULOSIS; MYCOBACTERIUM TUBERCULOSIS; TREATMENT OUTCOME;

ACETAMIDES; ACIDOSIS, LACTIC; ANTI-INFECTIVE AGENTS; FATAL OUTCOME; HUMANS; MALE; MIDDLE AGED; OXAZOLIDINONES; TIME FACTORS; TUBERCULOSIS, MULTIDRUG-RESISTANT; TUBERCULOSIS, PULMONARY;

EID: 70349268074     PISSN: 09536205     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejim.2008.12.002     Document Type: Article

References (6)

1. Ntziora F., and Falagas M.E. Linezolid for the treatment of patients with mycobacterial infection: a systematic review. Int J Tuberc Lung Dis 11 (2007) 606-611
2. Yew W.W., Chau C.H., and Wen K.H. Linezolid in the treatment of 'difficult' multidrug-resistant tuberculosis. Int J Tuberc Lung Dis 12 (2008) 345-346
3. Narita M., Tsuji B.T., and Yu V.L. Linezolid-associated peripheral and optic neuropathy, lactic acidosis and serotonin syndrome. Pharmacotherapy 27 (2007) 1189-1197
4. Palenzuela L., Hahn N.M., Nelson R.P., Arno J.N., Schobert C., and Bethel R. Does linezolid cause lactic acidosis by inhibiting mitochondrial protein synthesis?. Clin Infect Dis 40 12 (2005) e113-e116
5. Park I.N., Hong S.B., Oh Y.M., Kim M.N., Lim C.M., Lee S.D., et al. Efficacy and tolerability of daily-half dose linezolid in patients with intractable multidrug-resistant tuberculosis. J Antimicrob Chemother 58 (2006) 701-704
6. World Health Organization. Report of the meeting of the WHO global task force on extensively drug-resistant tuberculosis. Available at: http://whqlibdoc.who.int/hq/2007/who_htm_tb_2007.375_eng.pdf. Accessed July 7, 2008.