메뉴 건너뛰기




Volumn 19, Issue 3, 2009, Pages 233-242

Cleavage of HPV-16 E6/E7 mRNA mediated by modified 10-23 deoxyribozymes

Author keywords

[No Author keywords available]

Indexed keywords

DEOXYRIBOZYME; LOCKED NUCLEIC ACID; MESSENGER RNA; PROTEIN E6; PROTEIN E7;

EID: 70349267982     PISSN: 15454576     EISSN: None     Source Type: Journal    
DOI: 10.1089/oli.2009.0193     Document Type: Article
Times cited : (24)

References (59)
  • 1
    • 0031457918 scopus 로고    scopus 로고
    • Toxicologic effects of an oli-godeoxynucleotide phosphorothioate and its analogs following intravenous administration in rats
    • AGRAWAL, S., ZHAO, Q., JIANG, Z., OLIVER, C., GILES, H., HEATH, J., and SEROTA, D. (1997). Toxicologic effects of an oli-godeoxynucleotide phosphorothioate and its analogs following intravenous administration in rats. Antisense Nucleic Acid Drug Dev. 7, 575-584.
    • (1997) Antisense Nucleic Acid Drug Dev , vol.7 , pp. 575-584
    • Agrawal, S.1    Zhao, Q.2    Jiang, Z.3    Oliver, C.4    Giles, H.5    Heath, J.6    Serota, D.7
  • 2
    • 57849084800 scopus 로고    scopus 로고
    • Nucleic acids as therapeutic agents
    • ALVAREZ-SALAS, L.M. (2008). Nucleic acids as therapeutic agents. Curr. Top. Med. Chem. 8, 1379-1404.
    • (2008) Curr. Top. Med. Chem. , vol.8 , pp. 1379-1404
    • Alvarez-Salas, L.M.1
  • 3
    • 0032740776 scopus 로고    scopus 로고
    • Growth inhibition of cervical tumor cells by antisense oli-godeoxynucleotides directed to the human papillomavirus type 16 E6 gene
    • ALVAREZ-SALAS, L.M., ARPAWONG, T.E., and DIPAOLO, J.A. (1999). Growth inhibition of cervical tumor cells by antisense oli-godeoxynucleotides directed to the human papillomavirus type 16 E6 gene. Antisense Nucleic Acid Drug Dev. 9, 441-450.
    • (1999) Antisense Nucleic Acid Drug Dev , vol.9 , pp. 441-450
    • Alvarez-Salas, L.M.1    Arpawong, T.E.2    Dipaolo, J.A.3
  • 7
    • 1842588051 scopus 로고    scopus 로고
    • Gene silencing nucleic acids designed by scanning arrays: Anti-EGFR activity of siRNA, ribozyme and DNA enzymes targeting a single hybridization-accessible region using the same delivery system
    • BEALE, G., HOLLINS, A.J., BENBOUBETRA, M., SOHAIL, M., FOX, S.P., BENTER, I., and AKHTAR, S. (2003). Gene silencing nucleic acids designed by scanning arrays: anti-EGFR activity of siRNA, ribozyme and DNA enzymes targeting a single hybridization-accessible region using the same delivery system. J. Drug Target. 11, 449-456.
    • (2003) J. Drug Target. , vol.11 , pp. 449-456
    • Beale, G.1    Hollins, A.J.2    Benboubetra, M.3    Sohail, M.4    Fox, S.P.5    Benter, I.6    Akhtar, S.7
  • 8
    • 7544244886 scopus 로고    scopus 로고
    • Antisense activity detection by inhibition of f uorescence resonance energy transfer
    • BENITEZ-HESS, M.L., DIPAOLO, J.A., and ALVAREZ-SALAS, L.M. (2004). Antisense activity detection by inhibition of f uorescence resonance energy transfer. Luminescence. 19, 85-93.
    • (2004) Luminescence , vol.19 , pp. 85-93
    • Benitez-Hess, M.L.1    Dipaolo, J.A.2    Alvarez-Salas, L.M.3
  • 9
    • 35348911812 scopus 로고    scopus 로고
    • Brothers in arms. DNA enzymes, short interfering RNA, and the emerging wave of small-molecule nucleic acid-based gene-silencing strategies
    • BHINDI, R., FAHMY, R.G., LOWE, H.C., CHESTERMAN, C.N., DASS, C.R., CAIRNS, M.J., SARAVOLAC, E.G., SUN, L.Q., and KHACHIGIAN, L.M. (2007). Brothers in arms. DNA enzymes, short interfering RNA, and the emerging wave of small-molecule nucleic acid-based gene-silencing strategies. Am. J. Pathol. 171, 1079-1088.
    • (2007) Am. J. Pathol. , vol.171 , pp. 1079-1088
    • Bhindi, R.1    Fahmy, R.G.2    Lowe, H.C.3    Chesterman, C.N.4    Dass, C.R.5    Cairns, M.J.6    Saravolac, E.G.7    Sun, L.Q.8    Khachigian, L.M.9
  • 10
    • 0034604510 scopus 로고    scopus 로고
    • Structuralstudies of LNA:R NA duplexes by N M R: Conformat io n s and implications for RNase H activity
    • BONDENSGAARD, K., PETERSEN, M., SINGH, S.K., RAJWANSHI, V.K., KUMAR, R., WENGEL, J., and JACOBSEN, J.P. (2000). St r uc t u ra l st ud i e s of LNA:R NA duplexes by N M R: con f o r mat io n s and implications for RNase H activity. Chemistry. 6, 2687-2695.
    • (2000) Chemistry , vol.6 , pp. 2687-2695
    • Bondensgaard, K.1    Petersen, M.2    Singh, S.K.3    Rajwanshi, V.K.4    Kumar, R.5    Wengel, J.6    Jacobsen, J.P.7
  • 11
    • 0038131065 scopus 로고    scopus 로고
    • A lead-dependent DNAzyme with a two-step mechanism
    • BROWN, A.K., LI, J., PAVOT, C.M., and LU, Y. (2003). A lead-dependent DNAzyme with a two-step mechanism. Biochemistry. 42, 7152-7161.
    • (2003) Biochemistry , vol.42 , pp. 7152-7161
    • Brown, A.K.1    Li, J.2    Pavot, C.M.3    Lu, Y.4
  • 12
    • 0033761964 scopus 로고    scopus 로고
    • The inf uence of arm length asymmetry and base substitution on the activity of the 10-23 DNA enzyme
    • CAIRNS, M.J., HOPKINS, T.M., WITHERINGTON, C., and SUN, L.Q. (2000). The inf uence of arm length asymmetry and base substitution on the activity of the 10-23 DNA enzyme. Antisense Nucleic Acid Drug Dev. 10, 323-332.
    • (2000) Antisense Nucleic Acid Drug Dev , vol.10 , pp. 323-332
    • Cairns, M.J.1    Hopkins, T.M.2    Witherington, C.3    Sun, L.Q.4
  • 14
    • 0038489114 scopus 로고    scopus 로고
    • Inhibition of HIV-1 gene expression by novel DNA enzymes targeted to cleave HIV-1 TAR RNA: Potential effectiveness against all HIV-1 isolates
    • CHAKRABORTI, S., and BANERJEA, A.C. (2003). Inhibition of HIV-1 gene expression by novel DNA enzymes targeted to cleave HIV-1 TAR RNA: potential effectiveness against all HIV-1 isolates. Mol. Ther. 7, 817-826.
    • (2003) Mol. Ther. , vol.7 , pp. 817-826
    • Chakraborti, S.1    Banerjea, A.C.2
  • 15
    • 0036510605 scopus 로고    scopus 로고
    • DNAzymes to beta 1 and beta 3 mRNA down-regulate expression of the targeted integrins and inhibit endothelial cell capillary tube formation in f brin and matrigel
    • CIESLAK, M., NIEWIAROWSKA, J., NAWROT, M., KOZIOLKIEWICZ, M., STEC, W.J., and CIERNIEWSKI, C.S. (2002). DNAzymes to beta 1 and beta 3 mRNA down-regulate expression of the targeted integrins and inhibit endothelial cell capillary tube formation in f brin and matrigel. J. Biol. Chem. 277, 6779-6787.
    • (2002) J. Biol. Chem. , vol.277 , pp. 6779-6787
    • Cieslak, M.1    Niewiarowska, J.2    Nawrot, M.3    Koziolkiewicz, M.4    Stec, W.J.5    Cierniewski, C.S.6
  • 16
    • 0036606669 scopus 로고    scopus 로고
    • Design and characterization of decoy oligonucleotides containing locked nucleic acids
    • CRINELLI, R., BIANCHI, M., GENTILINI, L., and MAGNANI, M. (2002). Design and characterization of decoy oligonucleotides containing locked nucleic acids. Nucleic Acids Res. 30, 2435-2443.
    • (2002) Nucleic Acids Res , vol.30 , pp. 2435-2443
    • Crinelli, R.1    Bianchi, M.2    Gentilini, L.3    Magnani, M.4
  • 17
    • 2942631142 scopus 로고    scopus 로고
    • LNA/DNA chimeric oligomers mimic RNA aptamers targeted to the TAR RNA element of HIV-1
    • DARFEUILLE, F., HANSEN, J.B., ORUM, H., DI PRIMO, C., and TOULME, J.J. (2004). LNA/DNA chimeric oligomers mimic RNA aptamers targeted to the TAR RNA element of HIV-1. Nucleic Acids Res. 32, 3101-3107.
    • (2004) Nucleic Acids Res , vol.32 , pp. 3101-3107
    • Darfeuille, F.1    Hansen, J.B.2    Orum, H.3    Di Primo, C.4    Toulme, J.J.5
  • 18
    • 39749165700 scopus 로고    scopus 로고
    • DNAzyme technology and cancer therapy: Cleave and let die
    • DASS, C.R., CHOONG, P.F., and KHACHIGIAN, L.M. (2008). DNAzyme technology and cancer therapy: cleave and let die. Mol. Cancer Ther. 7, 243-251.
    • (2008) Mol. Cancer Ther. , vol.7 , pp. 243-251
    • Dass, C.R.1    Choong, P.F.2    Khachigian, L.M.3
  • 19
    • 0036811085 scopus 로고    scopus 로고
    • Cellular uptake, distribution, and stability of 10-23 deoxyribozymes
    • DASS, C.R., SARAVOLAC, E.G., LI, Y., and SUN, L.Q. (2002). Cellular uptake, distribution, and stability of 10-23 deoxyribozymes. Antisense Nucleic Acid Drug Dev. 12, 289-299.
    • (2002) Antisense Nucleic Acid Drug Dev , vol.12 , pp. 289-299
    • Dass, C.R.1    Saravolac, E.G.2    Li, Y.3    Sun, L.Q.4
  • 20
    • 37249019972 scopus 로고    scopus 로고
    • The advantages of being locked. Assessing the cleavage of short and long RNAs by locked nucleic acid-containing 8-17 deoxyribozymes
    • DONINI, S., CLERICI, M., WENGEL, J., VESTER, B., and PERACCHI, A. (2007). The advantages of being locked. Assessing the cleavage of short and long RNAs by locked nucleic acid-containing 8-17 deoxyribozymes. J. Biol. Chem. 282, 35510-35518.
    • (2007) J. Biol. Chem. , vol.282 , pp. 35510-35518
    • Donini, S.1    Clerici, M.2    Wengel, J.3    Vester, B.4    Peracchi, A.5
  • 21
    • 0024535228 scopus 로고
    • The human papilloma virus-16 E7 oncoprotein is able to bind to the retinoblastoma gene product
    • DYSON, N., HOWLEY, P.M., MUNGER, K., and HARLOW, E. (1989). The human papilloma virus-16 E7 oncoprotein is able to bind to the retinoblastoma gene product. Science. 243, 934-937.
    • (1989) Science , vol.243 , pp. 934-937
    • Dyson, N.1    Howley, P.M.2    Munger, K.3    Harlow, E.4
  • 22
    • 30844457323 scopus 로고    scopus 로고
    • Evaluation of LNA-modif ed DNAzymes targeting a single nucleotide polymorphism in the large subunit of RNA poly-merase II
    • FLUITER, K., FRIEDEN, M., VREIJLING, J., KOCH, T., and BAAS, F. (2005). Evaluation of LNA-modif ed DNAzymes targeting a single nucleotide polymorphism in the large subunit of RNA poly-merase II. Oligonucleotides. 15, 246-254.
    • (2005) Oligonucleotides , vol.15 , pp. 246-254
    • Fluiter, K.1    Frieden, M.2    Vreijling, J.3    Koch, T.4    Baas, F.5
  • 24
    • 0035253125 scopus 로고    scopus 로고
    • Inhibition of hepatitis B virus X gene expression by novel DNA enzymes
    • GOILA, R., and BANERJEA, A.C. (2001). Inhibition of hepatitis B virus X gene expression by novel DNA enzymes. Biochem. J. 353, 701-708.
    • (2001) Biochem. J. , vol.353 , pp. 701-708
    • Goila, R.1    Banerjea, A.C.2
  • 25
    • 33646857275 scopus 로고    scopus 로고
    • A bacterial reporter system for the evaluation of antisense oligodeoxynucleotides directed against human papillomavirus type 16 (HPV-16)
    • GUAPILLO, M.R., MARQUEZ-GUTIÉRREZ, M.A., BENITEZ-HESS, M.L., and ALVAREZ-SALAS, L.M. (2006). A bacterial reporter system for the evaluation of antisense oligodeoxynucleotides directed against human papillomavirus type 16 (HPV-16). Arch. Med. Res. 37, 584-592.
    • (2006) Arch. Med. Res. , vol.37 , pp. 584-592
    • Guapillo, M.R.1    Marquez-Gutiérrez, M.A.2    Benitez-Hess, M.L.3    Alvarez-Salas, L.M.4
  • 26
    • 0029945037 scopus 로고    scopus 로고
    • Unexpected anisotropy in substrate cleavage rates by asymmetric hammerhead ribozymes
    • HENDRY, P., and MCCALL, M. (1996). Unexpected anisotropy in substrate cleavage rates by asymmetric hammerhead ribozymes. Nucleic Acids Res. 24, 2679-2684.
    • (1996) Nucleic Acids Res , vol.24 , pp. 2679-2684
    • Hendry, P.1    McCall, M.2
  • 27
    • 0037026601 scopus 로고    scopus 로고
    • Selective silencing of viral gene expression in HPV-positive human cervical carcinoma cells treated with siRNA, a primer of RNA interference
    • JIANG, M., and MILNER, J. (2002). Selective silencing of viral gene expression in HPV-positive human cervical carcinoma cells treated with siRNA, a primer of RNA interference. Oncogene. 21, 6041-6048.
    • (2002) Oncogene , vol.21 , pp. 6041-6048
    • Jiang, M.1    Milner, J.2
  • 28
    • 0036510780 scopus 로고    scopus 로고
    • Comparative study of DNA enzymes and ribozymes against the same full-length messenger RNA of the vanilloid receptor subtype i
    • KURRECK, J., BIEBER, B., JAHNEL, R., and ERDMANN, V.A. (2002). Comparative study of DNA enzymes and ribozymes against the same full-length messenger RNA of the vanilloid receptor subtype I. J. Biol. Chem. 277, 7099-7107.
    • (2002) J. Biol. Chem. , vol.277 , pp. 7099-7107
    • Kurreck, J.1    Bieber, B.2    Jahnel, R.3    Erdmann, V.A.4
  • 29
    • 0024458830 scopus 로고
    • A rapid f uorometric method for semiautomated determination of cytotoxicity and cellular proliferation of human tumor cell lines in microculture
    • LARSSON, R., and NYGREN, P. (1989). A rapid f uorometric method for semiautomated determination of cytotoxicity and cellular proliferation of human tumor cell lines in microculture. Anticancer Res. 9, 1111-1119.
    • (1989) Anticancer Res , vol.9 , pp. 1111-1119
    • Larsson, R.1    Nygren, P.2
  • 30
    • 0034650291 scopus 로고    scopus 로고
    • In vitro selection and characterization of a highly eff cient Zn(II)-dependent RNA-cleaving deoxyribozyme
    • LI, J., ZHENG, W., KWON, A.H., and LU, Y. (2000). In vitro selection and characterization of a highly eff cient Zn(II)-dependent RNA-cleaving deoxyribozyme. Nucleic Acids Res. 28, 481-488.
    • (2000) Nucleic Acids Res , vol.28 , pp. 481-488
    • Li, J.1    Zheng, W.2    Kwon, A.H.3    Lu, Y.4
  • 31
    • 34548406407 scopus 로고    scopus 로고
    • Effect of combined anti-sense oligodeoxynucleotides directed against the human papil-lomavirus type 16 on cervical carcinoma cells
    • MARQUEZ-GUTIERREZ, M.A., BENITEZ-HESS, M.L., DIPAOLO, J.A., and ALVAREZ-SALAS, L.M. (2007). Effect of combined anti-sense oligodeoxynucleotides directed against the human papil-lomavirus type 16 on cervical carcinoma cells. Arch. Med. Res. 38, 730-738.
    • (2007) Arch. Med. Res. , vol.38 , pp. 730-738
    • Marquez-Gutierrez, M.A.1    Benitez-Hess, M.L.2    Dipaolo, J.A.3    Alvarez-Salas, L.M.4
  • 32
    • 2942642252 scopus 로고    scopus 로고
    • Inhibition of human breast carcinoma proliferation, migration, chemoinvasion and solid tumour growth by DNAzymes targeting the zinc f nger transcription factor EGR-1
    • MITCHELL, A., DASS, C.R., SUN, L.Q., and KHACHIGIAN, L.M. (2004). Inhibition of human breast carcinoma proliferation, migration, chemoinvasion and solid tumour growth by DNAzymes targeting the zinc f nger transcription factor EGR-1. Nucleic Acids Res. 32, 3065-3069.
    • (2004) Nucleic Acids Res. , vol.32 , pp. 3065-3069
    • Mitchell, A.1    Dass, C.R.2    Sun, L.Q.3    Khachigian, L.M.4
  • 33
    • 0024428508 scopus 로고
    • The E6 and E7 genes of the human papillo-mavirus type 16 together are necessary and suff cient for transformation of primary human keratinocytes
    • MUNGER, K., PHELPS, W.C., BUBB, V., HOWLEY, P.M., and SCHLEGEL, R. (1989). The E6 and E7 genes of the human papillo-mavirus type 16 together are necessary and suff cient for transformation of primary human keratinocytes. J. Virol. 63, 4417-4421.
    • (1989) J. Virol. , vol.63 , pp. 4417-4421
    • Munger, K.1    Phelps, W.C.2    Bubb, V.3    Howley, P.M.4    Schlegel, R.5
  • 34
    • 33846811414 scopus 로고    scopus 로고
    • Mapping of the functional phosphate groups in the catalytic core of deoxyribozyme 10-23
    • NAWROT, B., WIDERA, K., WOJCIK, M., REBOWSKA, B., NOWAK, G., and STEC, W.J. (2007). Mapping of the functional phosphate groups in the catalytic core of deoxyribozyme 10-23. FEBS J. 274, 1062-1072.
    • (2007) FEBS J. , vol.274 , pp. 1062-1072
    • Nawrot, B.1    Widera, K.2    Wojcik, M.3    Rebowska, B.4    Nowak, G.5    Stec, W.J.6
  • 35
    • 0032527839 scopus 로고    scopus 로고
    • Effects of helical structures formed by the binding arms of DNAzymes and their substrates on catalytic activity
    • OTA, N., WARASHINA, M., HIRANO, K., HATANAKA, K., and TAIRA, K. (1998). Effects of helical structures formed by the binding arms of DNAzymes and their substrates on catalytic activity. Nucleic Acids Res. 26, 3385-3391.
    • (1998) Nucleic Acids Res , vol.26 , pp. 3385-3391
    • Ota, N.1    Warashina, M.2    Hirano, K.3    Hatanaka, K.4    Taira, K.5
  • 36
    • 0034697291 scopus 로고    scopus 로고
    • Preferential activation of the 8-17 deoxyri-bozyme by Ca(2+) ions. Evidence for the identity of 8-17 with the catalytic domain of the Mg5 deoxyribozyme
    • PERACCHI, A. (2000). Preferential activation of the 8-17 deoxyri-bozyme by Ca(2+) ions. Evidence for the identity of 8-17 with the catalytic domain of the Mg5 deoxyribozyme. J. Biol. Chem. 275, 11693-11697.
    • (2000) J. Biol. Chem. , vol.275 , pp. 11693-11697
    • Peracchi, A.1
  • 37
    • 0037310844 scopus 로고    scopus 로고
    • LNA: A versatile tool for therapeutics and genomics
    • PETERSEN, M., and WENGEL, J. (2003). LNA: a versatile tool for therapeutics and genomics. Trends Biotechnol. 21, 74-81.
    • (2003) Trends Biotechnol , vol.21 , pp. 74-81
    • Petersen, M.1    Wengel, J.2
  • 38
    • 0023152810 scopus 로고
    • Transformation of human f broblasts and keratinocytes with human papillomavirus type 16 DNA
    • PIRISI, L., YASUMOTO, S., FELLER, M., DONIGER, J., and DIPAOLO, J.A. (1987). Transformation of human f broblasts and keratinocytes with human papillomavirus type 16 DNA. J. Virol. 61, 1061-1066.
    • (1987) J. Virol. , vol.61 , pp. 1061-1066
    • Pirisi, L.1    Yasumoto, S.2    Feller, M.3    Doniger, J.4    Dipaolo, J.A.5
  • 39
    • 0034242456 scopus 로고    scopus 로고
    • Regulation of cellular magnesium
    • ROMANI, A.M., and SCARPA, A. (2000). Regulation of cellular magnesium. Front. Biosci. 5, D720-D734.
    • (2000) Front. Biosci. , vol.5
    • Romani, A.M.1    Scarpa, A.2
  • 40
    • 0030898510 scopus 로고    scopus 로고
    • A general purpose RNA-cleaving DNA enzyme
    • SANTORO, S.W., and JOYCE, G.F. (1997). A general purpose RNA-cleaving DNA enzyme. Proc. Natl. Acad. Sci. USA. 94, 4262-4266.
    • (1997) Proc. Natl. Acad. Sci. USA. , vol.94 , pp. 4262-4266
    • Santoro, S.W.1    Joyce, G.F.2
  • 41
    • 0032558463 scopus 로고    scopus 로고
    • Mechanism and utility of an RNA-cleaving DNA enzyme
    • SANTORO, S.W., and JOYCE, G.F. (1998). Mechanism and utility of an RNA-cleaving DNA enzyme. Biochemistry. 37, 13330-13342.
    • (1998) Biochemistry , vol.37 , pp. 13330-13342
    • Santoro, S.W.1    Joyce, G.F.2
  • 44
    • 24144458271 scopus 로고    scopus 로고
    • Ribozymes, DNAzymes and small interfering RNAs as therapeutics
    • DOI 10.2174/1389450054863653
    • SIOUD, M., and IVERSEN, P.O. (2005). Ribozymes, DNAzymes and small interfering RNAs as therapeutics. Curr. Drug Targets 6, 647-653. (Pubitemid 41236548)
    • (2005) Current Drug Targets , vol.6 , Issue.6 , pp. 647-653
    • Sioud, M.1    Iversen, P.O.2
  • 45
    • 34247533679 scopus 로고    scopus 로고
    • DNA-enzyme-mediated cleavage of human immunodef cienc virus type 1 Gag RNA is signif cantly augmented by antisense-DNA molecules targeted to hybridize close to the cleavage site
    • SOOD, V., GUPTA, N., BANO, A.S., and BANERJEA, A.C. (2007). DNA-enzyme-mediated cleavage of human immunodef cienc virus type 1 Gag RNA is signif cantly augmented by antisense-DNA molecules targeted to hybridize close to the cleavage site. Oligonucleotides. 17, 113-121.
    • (2007) Oligonucleotides , vol.17 , pp. 113-121
    • Sood, V.1    Gupta, N.2    Bano, A.S.3    Banerjea, A.C.4
  • 46
    • 1342329316 scopus 로고    scopus 로고
    • A new modif ed DNA enzyme that targets inf uenza virus A mRNA inhibits viral infection in cultured cells
    • TAKAHASHI, H., HAMAZAKI, H., HABU, Y., HAYASHI, M., ABE, T., MIYANO-KUROSAKI, N., and TAKAKU, H. (2004). A new modif ed DNA enzyme that targets inf uenza virus A mRNA inhibits viral infection in cultured cells. FEBS Lett. 560, 69-74.
    • (2004) FEBS Lett , vol.560 , pp. 69-74
    • Takahashi, H.1    Hamazaki, H.2    Habu, Y.3    Hayashi, M.4    Abe, T.5    Miyano-Kurosaki, N.6    Takaku, H.7
  • 47
    • 0028823757 scopus 로고
    • In vitro and in vivo inhibition of human papillomavirus type 16 E6 and E7 genes
    • TAN, T.M., and TING, R.C. (1995). In vitro and in vivo inhibition of human papillomavirus type 16 E6 and E7 genes. Cancer Res. 55, 4599-4605.
    • (1995) Cancer Res , vol.55 , pp. 4599-4605
    • Tan, T.M.1    Ting, R.C.2
  • 49
    • 33645100908 scopus 로고    scopus 로고
    • Cleavage of intracellu-lar hepatitis C RNA in the virus core protein coding region by deoxyribozymes
    • TREPANIER, J., TANNER, J.E., MOMPARLER, R.L., LE, O.N., ALVAREZ, F., and ALFIERI, C. (2006). Cleavage of intracellu-lar hepatitis C RNA in the virus core protein coding region by deoxyribozymes. J. Viral. Hepat. 13, 131-138.
    • (2006) J. Viral. Hepat. , vol.13 , pp. 131-138
    • Trepanier, J.1    Tanner, J.E.2    Momparler, R.L.3    Le, O.N.4    Alvarez, F.5    Alfieri, C.6
  • 50
    • 0033118276 scopus 로고    scopus 로고
    • Kinetic selection of HPV 16 E6/ E7-directed antisense nucleic acids: Anti-proliferative effects on HPV 16-transformed cells
    • VENTURINI, F., BRASPENNING, J., HOMANN, M., GISSMANN, L., and SCZAKIEL, G. (1999). Kinetic selection of HPV 16 E6/ E7-directed antisense nucleic acids: anti-proliferative effects on HPV 16-transformed cells. Nucleic Acids Res. 27, 1585-1592.
    • (1999) Nucleic Acids Res , vol.27 , pp. 1585-1592
    • Venturini, F.1    Braspenning, J.2    Homann, M.3    Gissmann, L.4    Sczakiel, G.5
  • 52
    • 0037145999 scopus 로고    scopus 로고
    • LNAzymes: Incorporation of LNA-type monomers into DNAzymes markedly increases RNA cleavage
    • VESTER, B., LUNDBERG, L.B., SORENSEN, M.D., BABU, B.R., DOUTHWAITE, S., and WENGEL, J. (2002). LNAzymes: incorporation of LNA-type monomers into DNAzymes markedly increases RNA cleavage. J. Am. Chem. Soc. 124, 13682-13683.
    • (2002) J. Am. Chem. Soc. , vol.124 , pp. 13682-13683
    • Vester, B.1    Lundberg, L.B.2    Sorensen, M.D.3    Babu, B.R.4    Douthwaite, S.5    Wengel, J.6
  • 55
    • 0033117651 scopus 로고    scopus 로고
    • Extremely high and specif c activity of DNA enzymes in cells with a Philadelphia chromosome
    • WARASHINA, M., KUWABARA, T., NAKAMATSU, Y., and TAIRA, K. (1999). Extremely high and specif c activity of DNA enzymes in cells with a Philadelphia chromosome. Chem. Biol. 6, 237-250.
    • (1999) Chem. Biol. , vol.6 , pp. 237-250
    • Warashina, M.1    Kuwabara, T.2    Nakamatsu, Y.3    Taira, K.4
  • 56
    • 0025271203 scopus 로고
    • Association of human papillomavirus types 16 and 18 E6 proteins with p53
    • WERNESS, B.A., LEVINE, A.J., and HOWLEY, P.M. (1990). Association of human papillomavirus types 16 and 18 E6 proteins with p53. Science. 248, 76-79.
    • (1990) Science , vol.248 , pp. 76-79
    • Werness, B.A.1    Levine, A.J.2    Howley, P.M.3
  • 57
    • 0033589752 scopus 로고    scopus 로고
    • Inhibition of bcr-abl oncogene expression by novel deoxyribozymes (DNAzymes
    • WU, Y., YU, L., MCMAHON, R., ROSSI, J.J., FORMAN, S.J., and SNYDER, D.S. (1999). Inhibition of bcr-abl oncogene expression by novel deoxyribozymes (DNAzymes). Hum. Gene Ther. 10, 2847-2857.
    • (1999) Hum. Gene Ther. , vol.10 , pp. 2847-2857
    • Wu, Y.1    Yu, L.2    McMahon, R.3    Rossi, J.J.4    Forman, S.J.5    Snyder, D.S.6
  • 58
    • 0037175009 scopus 로고    scopus 로고
    • Sequence requirements in the catalytic core of the "10-23" DNA enzyme
    • ZABOROWSKA, Z., FURSTE, J.P., ERDMANN, V.A., and KURRECK, J. (2002). Sequence requirements in the catalytic core of the "10-23" DNA enzyme. J. Biol. Chem. 277, 40617-40622.
    • (2002) J. Biol. Chem. , vol.277 , pp. 40617-40622
    • Zaborowska, Z.1    Furste, J.P.2    Erdmann, V.A.3    Kurreck, J.4
  • 59
    • 0030577120 scopus 로고    scopus 로고
    • Papillomavirus infections - A major cause of human cancers
    • DOI 10.1016/0304-419X(96)00020-0
    • ZUR HAUSEN, H. (1996). Papillomavirus infections a major cause of human cancers. Biochim. Biophys. Acta 1288, F55-F78. (Pubitemid 26335492)
    • (1996) Biochimica et Biophysica Acta - Reviews on Cancer , vol.1288 , Issue.2
    • Zur Hausen, H.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.