-
1
-
-
0031457918
-
Toxicologic effects of an oli-godeoxynucleotide phosphorothioate and its analogs following intravenous administration in rats
-
AGRAWAL, S., ZHAO, Q., JIANG, Z., OLIVER, C., GILES, H., HEATH, J., and SEROTA, D. (1997). Toxicologic effects of an oli-godeoxynucleotide phosphorothioate and its analogs following intravenous administration in rats. Antisense Nucleic Acid Drug Dev. 7, 575-584.
-
(1997)
Antisense Nucleic Acid Drug Dev
, vol.7
, pp. 575-584
-
-
Agrawal, S.1
Zhao, Q.2
Jiang, Z.3
Oliver, C.4
Giles, H.5
Heath, J.6
Serota, D.7
-
2
-
-
57849084800
-
Nucleic acids as therapeutic agents
-
ALVAREZ-SALAS, L.M. (2008). Nucleic acids as therapeutic agents. Curr. Top. Med. Chem. 8, 1379-1404.
-
(2008)
Curr. Top. Med. Chem.
, vol.8
, pp. 1379-1404
-
-
Alvarez-Salas, L.M.1
-
3
-
-
0032740776
-
Growth inhibition of cervical tumor cells by antisense oli-godeoxynucleotides directed to the human papillomavirus type 16 E6 gene
-
ALVAREZ-SALAS, L.M., ARPAWONG, T.E., and DIPAOLO, J.A. (1999). Growth inhibition of cervical tumor cells by antisense oli-godeoxynucleotides directed to the human papillomavirus type 16 E6 gene. Antisense Nucleic Acid Drug Dev. 9, 441-450.
-
(1999)
Antisense Nucleic Acid Drug Dev
, vol.9
, pp. 441-450
-
-
Alvarez-Salas, L.M.1
Arpawong, T.E.2
Dipaolo, J.A.3
-
4
-
-
0032477870
-
Inhibition of HPV-16 E6/E7 immortalization of normal keratinocytes by hairpin ribozymes
-
ALVAREZ-SALAS, L.M., CULLINAN, A.E., SIWKOWSKI, A., HAMPEL, A., and DIPAOLO, J.A. (1998). Inhibition of HPV-16 E6/E7 immortalization of normal keratinocytes by hairpin ribozymes. Proc. Natl. Acad. Sci. USA. 95, 1189-1194.
-
(1998)
Proc. Natl. Acad. Sci. USA.
, vol.95
, pp. 1189-1194
-
-
Alvarez-Salas, L.M.1
Cullinan, A.E.2
Siwkowski, A.3
Hampel, A.4
Dipaolo, J.A.5
-
6
-
-
51849097818
-
A triplex ribozyme expression system based on a single hairpin ribozyme
-
AQUINO-JARQUIN, G., BENITEZ-HESS, M.L., DIPAOLO, J.A., and ALVAREZ-SALAS, L.M. (2008). A triplex ribozyme expression system based on a single hairpin ribozyme. Oligonucleotides. 18, 213-224.
-
(2008)
Oligonucleotides
, vol.18
, pp. 213-224
-
-
Aquino-Jarquin, G.1
Benitez-Hess, M.L.2
Dipaolo, J.A.3
Alvarez-Salas, L.M.4
-
7
-
-
1842588051
-
Gene silencing nucleic acids designed by scanning arrays: Anti-EGFR activity of siRNA, ribozyme and DNA enzymes targeting a single hybridization-accessible region using the same delivery system
-
BEALE, G., HOLLINS, A.J., BENBOUBETRA, M., SOHAIL, M., FOX, S.P., BENTER, I., and AKHTAR, S. (2003). Gene silencing nucleic acids designed by scanning arrays: anti-EGFR activity of siRNA, ribozyme and DNA enzymes targeting a single hybridization-accessible region using the same delivery system. J. Drug Target. 11, 449-456.
-
(2003)
J. Drug Target.
, vol.11
, pp. 449-456
-
-
Beale, G.1
Hollins, A.J.2
Benboubetra, M.3
Sohail, M.4
Fox, S.P.5
Benter, I.6
Akhtar, S.7
-
8
-
-
7544244886
-
Antisense activity detection by inhibition of f uorescence resonance energy transfer
-
BENITEZ-HESS, M.L., DIPAOLO, J.A., and ALVAREZ-SALAS, L.M. (2004). Antisense activity detection by inhibition of f uorescence resonance energy transfer. Luminescence. 19, 85-93.
-
(2004)
Luminescence
, vol.19
, pp. 85-93
-
-
Benitez-Hess, M.L.1
Dipaolo, J.A.2
Alvarez-Salas, L.M.3
-
9
-
-
35348911812
-
Brothers in arms. DNA enzymes, short interfering RNA, and the emerging wave of small-molecule nucleic acid-based gene-silencing strategies
-
BHINDI, R., FAHMY, R.G., LOWE, H.C., CHESTERMAN, C.N., DASS, C.R., CAIRNS, M.J., SARAVOLAC, E.G., SUN, L.Q., and KHACHIGIAN, L.M. (2007). Brothers in arms. DNA enzymes, short interfering RNA, and the emerging wave of small-molecule nucleic acid-based gene-silencing strategies. Am. J. Pathol. 171, 1079-1088.
-
(2007)
Am. J. Pathol.
, vol.171
, pp. 1079-1088
-
-
Bhindi, R.1
Fahmy, R.G.2
Lowe, H.C.3
Chesterman, C.N.4
Dass, C.R.5
Cairns, M.J.6
Saravolac, E.G.7
Sun, L.Q.8
Khachigian, L.M.9
-
10
-
-
0034604510
-
Structuralstudies of LNA:R NA duplexes by N M R: Conformat io n s and implications for RNase H activity
-
BONDENSGAARD, K., PETERSEN, M., SINGH, S.K., RAJWANSHI, V.K., KUMAR, R., WENGEL, J., and JACOBSEN, J.P. (2000). St r uc t u ra l st ud i e s of LNA:R NA duplexes by N M R: con f o r mat io n s and implications for RNase H activity. Chemistry. 6, 2687-2695.
-
(2000)
Chemistry
, vol.6
, pp. 2687-2695
-
-
Bondensgaard, K.1
Petersen, M.2
Singh, S.K.3
Rajwanshi, V.K.4
Kumar, R.5
Wengel, J.6
Jacobsen, J.P.7
-
11
-
-
0038131065
-
A lead-dependent DNAzyme with a two-step mechanism
-
BROWN, A.K., LI, J., PAVOT, C.M., and LU, Y. (2003). A lead-dependent DNAzyme with a two-step mechanism. Biochemistry. 42, 7152-7161.
-
(2003)
Biochemistry
, vol.42
, pp. 7152-7161
-
-
Brown, A.K.1
Li, J.2
Pavot, C.M.3
Lu, Y.4
-
12
-
-
0033761964
-
The inf uence of arm length asymmetry and base substitution on the activity of the 10-23 DNA enzyme
-
CAIRNS, M.J., HOPKINS, T.M., WITHERINGTON, C., and SUN, L.Q. (2000). The inf uence of arm length asymmetry and base substitution on the activity of the 10-23 DNA enzyme. Antisense Nucleic Acid Drug Dev. 10, 323-332.
-
(2000)
Antisense Nucleic Acid Drug Dev
, vol.10
, pp. 323-332
-
-
Cairns, M.J.1
Hopkins, T.M.2
Witherington, C.3
Sun, L.Q.4
-
13
-
-
0032912701
-
Target site selection for an RNA-cleaving catalytic DNA
-
CAIRNS, M.J., HOPKINS, T.M., WITHERINGTON, C., WANG, L., and SUN, L.Q. (1999). Target site selection for an RNA-cleaving catalytic DNA. Nat. Biotechnol. 17, 480-486.
-
(1999)
Nat. Biotechnol.
, vol.17
, pp. 480-486
-
-
Cairns, M.J.1
Hopkins, T.M.2
Witherington, C.3
Wang, L.4
Sun, L.Q.5
-
14
-
-
0038489114
-
Inhibition of HIV-1 gene expression by novel DNA enzymes targeted to cleave HIV-1 TAR RNA: Potential effectiveness against all HIV-1 isolates
-
CHAKRABORTI, S., and BANERJEA, A.C. (2003). Inhibition of HIV-1 gene expression by novel DNA enzymes targeted to cleave HIV-1 TAR RNA: potential effectiveness against all HIV-1 isolates. Mol. Ther. 7, 817-826.
-
(2003)
Mol. Ther.
, vol.7
, pp. 817-826
-
-
Chakraborti, S.1
Banerjea, A.C.2
-
15
-
-
0036510605
-
DNAzymes to beta 1 and beta 3 mRNA down-regulate expression of the targeted integrins and inhibit endothelial cell capillary tube formation in f brin and matrigel
-
CIESLAK, M., NIEWIAROWSKA, J., NAWROT, M., KOZIOLKIEWICZ, M., STEC, W.J., and CIERNIEWSKI, C.S. (2002). DNAzymes to beta 1 and beta 3 mRNA down-regulate expression of the targeted integrins and inhibit endothelial cell capillary tube formation in f brin and matrigel. J. Biol. Chem. 277, 6779-6787.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 6779-6787
-
-
Cieslak, M.1
Niewiarowska, J.2
Nawrot, M.3
Koziolkiewicz, M.4
Stec, W.J.5
Cierniewski, C.S.6
-
16
-
-
0036606669
-
Design and characterization of decoy oligonucleotides containing locked nucleic acids
-
CRINELLI, R., BIANCHI, M., GENTILINI, L., and MAGNANI, M. (2002). Design and characterization of decoy oligonucleotides containing locked nucleic acids. Nucleic Acids Res. 30, 2435-2443.
-
(2002)
Nucleic Acids Res
, vol.30
, pp. 2435-2443
-
-
Crinelli, R.1
Bianchi, M.2
Gentilini, L.3
Magnani, M.4
-
17
-
-
2942631142
-
LNA/DNA chimeric oligomers mimic RNA aptamers targeted to the TAR RNA element of HIV-1
-
DARFEUILLE, F., HANSEN, J.B., ORUM, H., DI PRIMO, C., and TOULME, J.J. (2004). LNA/DNA chimeric oligomers mimic RNA aptamers targeted to the TAR RNA element of HIV-1. Nucleic Acids Res. 32, 3101-3107.
-
(2004)
Nucleic Acids Res
, vol.32
, pp. 3101-3107
-
-
Darfeuille, F.1
Hansen, J.B.2
Orum, H.3
Di Primo, C.4
Toulme, J.J.5
-
18
-
-
39749165700
-
DNAzyme technology and cancer therapy: Cleave and let die
-
DASS, C.R., CHOONG, P.F., and KHACHIGIAN, L.M. (2008). DNAzyme technology and cancer therapy: cleave and let die. Mol. Cancer Ther. 7, 243-251.
-
(2008)
Mol. Cancer Ther.
, vol.7
, pp. 243-251
-
-
Dass, C.R.1
Choong, P.F.2
Khachigian, L.M.3
-
19
-
-
0036811085
-
Cellular uptake, distribution, and stability of 10-23 deoxyribozymes
-
DASS, C.R., SARAVOLAC, E.G., LI, Y., and SUN, L.Q. (2002). Cellular uptake, distribution, and stability of 10-23 deoxyribozymes. Antisense Nucleic Acid Drug Dev. 12, 289-299.
-
(2002)
Antisense Nucleic Acid Drug Dev
, vol.12
, pp. 289-299
-
-
Dass, C.R.1
Saravolac, E.G.2
Li, Y.3
Sun, L.Q.4
-
20
-
-
37249019972
-
The advantages of being locked. Assessing the cleavage of short and long RNAs by locked nucleic acid-containing 8-17 deoxyribozymes
-
DONINI, S., CLERICI, M., WENGEL, J., VESTER, B., and PERACCHI, A. (2007). The advantages of being locked. Assessing the cleavage of short and long RNAs by locked nucleic acid-containing 8-17 deoxyribozymes. J. Biol. Chem. 282, 35510-35518.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 35510-35518
-
-
Donini, S.1
Clerici, M.2
Wengel, J.3
Vester, B.4
Peracchi, A.5
-
21
-
-
0024535228
-
The human papilloma virus-16 E7 oncoprotein is able to bind to the retinoblastoma gene product
-
DYSON, N., HOWLEY, P.M., MUNGER, K., and HARLOW, E. (1989). The human papilloma virus-16 E7 oncoprotein is able to bind to the retinoblastoma gene product. Science. 243, 934-937.
-
(1989)
Science
, vol.243
, pp. 934-937
-
-
Dyson, N.1
Howley, P.M.2
Munger, K.3
Harlow, E.4
-
22
-
-
30844457323
-
Evaluation of LNA-modif ed DNAzymes targeting a single nucleotide polymorphism in the large subunit of RNA poly-merase II
-
FLUITER, K., FRIEDEN, M., VREIJLING, J., KOCH, T., and BAAS, F. (2005). Evaluation of LNA-modif ed DNAzymes targeting a single nucleotide polymorphism in the large subunit of RNA poly-merase II. Oligonucleotides. 15, 246-254.
-
(2005)
Oligonucleotides
, vol.15
, pp. 246-254
-
-
Fluiter, K.1
Frieden, M.2
Vreijling, J.3
Koch, T.4
Baas, F.5
-
23
-
-
70349265879
-
Effective cleavage of structured RNAs by tandems of 10-23 DNAzymes with 3′-modif ed oligo(2′-O-methylribonucleotide)-effectors
-
FOKINA, A., NOVOPASHINA, D., MESCHANINOVA, M., VOROBJEVA, M., ZENKOVA, M., FRANCOIS, J.C., and VENYAMINOVA, A. (2008). Effective cleavage of structured RNAs by tandems of 10-23 DNAzymes with 3′-modif ed oligo(2′-O- methylribonucleotide)-effectors. Nucleic Acids Symp. Ser. (Oxf.) 52:525-526.
-
(2008)
Nucleic Acids Symp. Ser. (Oxf.)
, vol.52
, pp. 525-526
-
-
Fokina, A.1
Novopashina, D.2
Meschaninova, M.3
Vorobjeva, M.4
Zenkova, M.5
Francois, J.C.6
Venyaminova, A.7
-
24
-
-
0035253125
-
Inhibition of hepatitis B virus X gene expression by novel DNA enzymes
-
GOILA, R., and BANERJEA, A.C. (2001). Inhibition of hepatitis B virus X gene expression by novel DNA enzymes. Biochem. J. 353, 701-708.
-
(2001)
Biochem. J.
, vol.353
, pp. 701-708
-
-
Goila, R.1
Banerjea, A.C.2
-
25
-
-
33646857275
-
A bacterial reporter system for the evaluation of antisense oligodeoxynucleotides directed against human papillomavirus type 16 (HPV-16)
-
GUAPILLO, M.R., MARQUEZ-GUTIÉRREZ, M.A., BENITEZ-HESS, M.L., and ALVAREZ-SALAS, L.M. (2006). A bacterial reporter system for the evaluation of antisense oligodeoxynucleotides directed against human papillomavirus type 16 (HPV-16). Arch. Med. Res. 37, 584-592.
-
(2006)
Arch. Med. Res.
, vol.37
, pp. 584-592
-
-
Guapillo, M.R.1
Marquez-Gutiérrez, M.A.2
Benitez-Hess, M.L.3
Alvarez-Salas, L.M.4
-
26
-
-
0029945037
-
Unexpected anisotropy in substrate cleavage rates by asymmetric hammerhead ribozymes
-
HENDRY, P., and MCCALL, M. (1996). Unexpected anisotropy in substrate cleavage rates by asymmetric hammerhead ribozymes. Nucleic Acids Res. 24, 2679-2684.
-
(1996)
Nucleic Acids Res
, vol.24
, pp. 2679-2684
-
-
Hendry, P.1
McCall, M.2
-
27
-
-
0037026601
-
Selective silencing of viral gene expression in HPV-positive human cervical carcinoma cells treated with siRNA, a primer of RNA interference
-
JIANG, M., and MILNER, J. (2002). Selective silencing of viral gene expression in HPV-positive human cervical carcinoma cells treated with siRNA, a primer of RNA interference. Oncogene. 21, 6041-6048.
-
(2002)
Oncogene
, vol.21
, pp. 6041-6048
-
-
Jiang, M.1
Milner, J.2
-
28
-
-
0036510780
-
Comparative study of DNA enzymes and ribozymes against the same full-length messenger RNA of the vanilloid receptor subtype i
-
KURRECK, J., BIEBER, B., JAHNEL, R., and ERDMANN, V.A. (2002). Comparative study of DNA enzymes and ribozymes against the same full-length messenger RNA of the vanilloid receptor subtype I. J. Biol. Chem. 277, 7099-7107.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 7099-7107
-
-
Kurreck, J.1
Bieber, B.2
Jahnel, R.3
Erdmann, V.A.4
-
29
-
-
0024458830
-
A rapid f uorometric method for semiautomated determination of cytotoxicity and cellular proliferation of human tumor cell lines in microculture
-
LARSSON, R., and NYGREN, P. (1989). A rapid f uorometric method for semiautomated determination of cytotoxicity and cellular proliferation of human tumor cell lines in microculture. Anticancer Res. 9, 1111-1119.
-
(1989)
Anticancer Res
, vol.9
, pp. 1111-1119
-
-
Larsson, R.1
Nygren, P.2
-
30
-
-
0034650291
-
In vitro selection and characterization of a highly eff cient Zn(II)-dependent RNA-cleaving deoxyribozyme
-
LI, J., ZHENG, W., KWON, A.H., and LU, Y. (2000). In vitro selection and characterization of a highly eff cient Zn(II)-dependent RNA-cleaving deoxyribozyme. Nucleic Acids Res. 28, 481-488.
-
(2000)
Nucleic Acids Res
, vol.28
, pp. 481-488
-
-
Li, J.1
Zheng, W.2
Kwon, A.H.3
Lu, Y.4
-
31
-
-
34548406407
-
Effect of combined anti-sense oligodeoxynucleotides directed against the human papil-lomavirus type 16 on cervical carcinoma cells
-
MARQUEZ-GUTIERREZ, M.A., BENITEZ-HESS, M.L., DIPAOLO, J.A., and ALVAREZ-SALAS, L.M. (2007). Effect of combined anti-sense oligodeoxynucleotides directed against the human papil-lomavirus type 16 on cervical carcinoma cells. Arch. Med. Res. 38, 730-738.
-
(2007)
Arch. Med. Res.
, vol.38
, pp. 730-738
-
-
Marquez-Gutierrez, M.A.1
Benitez-Hess, M.L.2
Dipaolo, J.A.3
Alvarez-Salas, L.M.4
-
32
-
-
2942642252
-
Inhibition of human breast carcinoma proliferation, migration, chemoinvasion and solid tumour growth by DNAzymes targeting the zinc f nger transcription factor EGR-1
-
MITCHELL, A., DASS, C.R., SUN, L.Q., and KHACHIGIAN, L.M. (2004). Inhibition of human breast carcinoma proliferation, migration, chemoinvasion and solid tumour growth by DNAzymes targeting the zinc f nger transcription factor EGR-1. Nucleic Acids Res. 32, 3065-3069.
-
(2004)
Nucleic Acids Res.
, vol.32
, pp. 3065-3069
-
-
Mitchell, A.1
Dass, C.R.2
Sun, L.Q.3
Khachigian, L.M.4
-
33
-
-
0024428508
-
The E6 and E7 genes of the human papillo-mavirus type 16 together are necessary and suff cient for transformation of primary human keratinocytes
-
MUNGER, K., PHELPS, W.C., BUBB, V., HOWLEY, P.M., and SCHLEGEL, R. (1989). The E6 and E7 genes of the human papillo-mavirus type 16 together are necessary and suff cient for transformation of primary human keratinocytes. J. Virol. 63, 4417-4421.
-
(1989)
J. Virol.
, vol.63
, pp. 4417-4421
-
-
Munger, K.1
Phelps, W.C.2
Bubb, V.3
Howley, P.M.4
Schlegel, R.5
-
34
-
-
33846811414
-
Mapping of the functional phosphate groups in the catalytic core of deoxyribozyme 10-23
-
NAWROT, B., WIDERA, K., WOJCIK, M., REBOWSKA, B., NOWAK, G., and STEC, W.J. (2007). Mapping of the functional phosphate groups in the catalytic core of deoxyribozyme 10-23. FEBS J. 274, 1062-1072.
-
(2007)
FEBS J.
, vol.274
, pp. 1062-1072
-
-
Nawrot, B.1
Widera, K.2
Wojcik, M.3
Rebowska, B.4
Nowak, G.5
Stec, W.J.6
-
35
-
-
0032527839
-
Effects of helical structures formed by the binding arms of DNAzymes and their substrates on catalytic activity
-
OTA, N., WARASHINA, M., HIRANO, K., HATANAKA, K., and TAIRA, K. (1998). Effects of helical structures formed by the binding arms of DNAzymes and their substrates on catalytic activity. Nucleic Acids Res. 26, 3385-3391.
-
(1998)
Nucleic Acids Res
, vol.26
, pp. 3385-3391
-
-
Ota, N.1
Warashina, M.2
Hirano, K.3
Hatanaka, K.4
Taira, K.5
-
36
-
-
0034697291
-
Preferential activation of the 8-17 deoxyri-bozyme by Ca(2+) ions. Evidence for the identity of 8-17 with the catalytic domain of the Mg5 deoxyribozyme
-
PERACCHI, A. (2000). Preferential activation of the 8-17 deoxyri-bozyme by Ca(2+) ions. Evidence for the identity of 8-17 with the catalytic domain of the Mg5 deoxyribozyme. J. Biol. Chem. 275, 11693-11697.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 11693-11697
-
-
Peracchi, A.1
-
37
-
-
0037310844
-
LNA: A versatile tool for therapeutics and genomics
-
PETERSEN, M., and WENGEL, J. (2003). LNA: a versatile tool for therapeutics and genomics. Trends Biotechnol. 21, 74-81.
-
(2003)
Trends Biotechnol
, vol.21
, pp. 74-81
-
-
Petersen, M.1
Wengel, J.2
-
38
-
-
0023152810
-
Transformation of human f broblasts and keratinocytes with human papillomavirus type 16 DNA
-
PIRISI, L., YASUMOTO, S., FELLER, M., DONIGER, J., and DIPAOLO, J.A. (1987). Transformation of human f broblasts and keratinocytes with human papillomavirus type 16 DNA. J. Virol. 61, 1061-1066.
-
(1987)
J. Virol.
, vol.61
, pp. 1061-1066
-
-
Pirisi, L.1
Yasumoto, S.2
Feller, M.3
Doniger, J.4
Dipaolo, J.A.5
-
39
-
-
0034242456
-
Regulation of cellular magnesium
-
ROMANI, A.M., and SCARPA, A. (2000). Regulation of cellular magnesium. Front. Biosci. 5, D720-D734.
-
(2000)
Front. Biosci.
, vol.5
-
-
Romani, A.M.1
Scarpa, A.2
-
40
-
-
0030898510
-
A general purpose RNA-cleaving DNA enzyme
-
SANTORO, S.W., and JOYCE, G.F. (1997). A general purpose RNA-cleaving DNA enzyme. Proc. Natl. Acad. Sci. USA. 94, 4262-4266.
-
(1997)
Proc. Natl. Acad. Sci. USA.
, vol.94
, pp. 4262-4266
-
-
Santoro, S.W.1
Joyce, G.F.2
-
41
-
-
0032558463
-
Mechanism and utility of an RNA-cleaving DNA enzyme
-
SANTORO, S.W., and JOYCE, G.F. (1998). Mechanism and utility of an RNA-cleaving DNA enzyme. Biochemistry. 37, 13330-13342.
-
(1998)
Biochemistry
, vol.37
, pp. 13330-13342
-
-
Santoro, S.W.1
Joyce, G.F.2
-
42
-
-
0034701302
-
RNA cleavage by a DNA enzyme with extended chemical functionality
-
SANTORO, S.W., JOYCE, G.F., SAKTHIVEL, K., GRAMATIKOVA, S., and BARBAS, C.F. (2000). RNA cleavage by a DNA enzyme with extended chemical functionality. J. Am. Chem. Soc. 122, 2433-2439.
-
(2000)
J. Am. Chem. Soc.
, vol.122
, pp. 2433-2439
-
-
Santoro, S.W.1
Joyce, G.F.2
Sakthivel, K.3
Gramatikova, S.4
Barbas, C.F.5
-
43
-
-
0344442416
-
RNA cleaving "10-23" DNAzymes with enhanced stability and activity
-
SCHUBERT, S., GUL, D.C., GRUNERT, H.P., ZEICHHARDT, H., ERDMANN, V.A., and KURRECK, J. (2003). RNA cleaving "10-23" DNAzymes with enhanced stability and activity. Nucleic Acids Res. 31, 5982-5992.
-
(2003)
Nucleic Acids Res
, vol.31
, pp. 5982-5992
-
-
Schubert, S.1
Gul, D.C.2
Grunert, H.P.3
Zeichhardt, H.4
Erdmann, V.A.5
Kurreck, J.6
-
44
-
-
24144458271
-
Ribozymes, DNAzymes and small interfering RNAs as therapeutics
-
DOI 10.2174/1389450054863653
-
SIOUD, M., and IVERSEN, P.O. (2005). Ribozymes, DNAzymes and small interfering RNAs as therapeutics. Curr. Drug Targets 6, 647-653. (Pubitemid 41236548)
-
(2005)
Current Drug Targets
, vol.6
, Issue.6
, pp. 647-653
-
-
Sioud, M.1
Iversen, P.O.2
-
45
-
-
34247533679
-
DNA-enzyme-mediated cleavage of human immunodef cienc virus type 1 Gag RNA is signif cantly augmented by antisense-DNA molecules targeted to hybridize close to the cleavage site
-
SOOD, V., GUPTA, N., BANO, A.S., and BANERJEA, A.C. (2007). DNA-enzyme-mediated cleavage of human immunodef cienc virus type 1 Gag RNA is signif cantly augmented by antisense-DNA molecules targeted to hybridize close to the cleavage site. Oligonucleotides. 17, 113-121.
-
(2007)
Oligonucleotides
, vol.17
, pp. 113-121
-
-
Sood, V.1
Gupta, N.2
Bano, A.S.3
Banerjea, A.C.4
-
46
-
-
1342329316
-
A new modif ed DNA enzyme that targets inf uenza virus A mRNA inhibits viral infection in cultured cells
-
TAKAHASHI, H., HAMAZAKI, H., HABU, Y., HAYASHI, M., ABE, T., MIYANO-KUROSAKI, N., and TAKAKU, H. (2004). A new modif ed DNA enzyme that targets inf uenza virus A mRNA inhibits viral infection in cultured cells. FEBS Lett. 560, 69-74.
-
(2004)
FEBS Lett
, vol.560
, pp. 69-74
-
-
Takahashi, H.1
Hamazaki, H.2
Habu, Y.3
Hayashi, M.4
Abe, T.5
Miyano-Kurosaki, N.6
Takaku, H.7
-
47
-
-
0028823757
-
In vitro and in vivo inhibition of human papillomavirus type 16 E6 and E7 genes
-
TAN, T.M., and TING, R.C. (1995). In vitro and in vivo inhibition of human papillomavirus type 16 E6 and E7 genes. Cancer Res. 55, 4599-4605.
-
(1995)
Cancer Res
, vol.55
, pp. 4599-4605
-
-
Tan, T.M.1
Ting, R.C.2
-
48
-
-
0034666079
-
In hibit ionofinfuenza virus replication in cultured cells by RNA-cleaving DNA enzyme
-
TOYODA, T., IMAMURA, Y., TAKAKU, H., KASHIWAGI, T., HARA, K., IWAHASHI, J., OHTSU, Y., TSUMURA, N., KATO, H., and HA MADA, N. (20 0 0). I n h ibit io n of i n f uenza virus replication in cultured cells by RNA-cleaving DNA enzyme. FEBS Lett. 481, 113-116.
-
(2000)
FEBS Lett
, vol.481
, pp. 113-116
-
-
Toyoda, T.1
Imamura, Y.2
Takaku, H.3
Kashiwagi, T.4
Hara, K.5
Iwahashi, J.6
Ohtsu, Y.7
Tsumura, N.8
Kato, H.9
Ha Mada, N.10
-
49
-
-
33645100908
-
Cleavage of intracellu-lar hepatitis C RNA in the virus core protein coding region by deoxyribozymes
-
TREPANIER, J., TANNER, J.E., MOMPARLER, R.L., LE, O.N., ALVAREZ, F., and ALFIERI, C. (2006). Cleavage of intracellu-lar hepatitis C RNA in the virus core protein coding region by deoxyribozymes. J. Viral. Hepat. 13, 131-138.
-
(2006)
J. Viral. Hepat.
, vol.13
, pp. 131-138
-
-
Trepanier, J.1
Tanner, J.E.2
Momparler, R.L.3
Le, O.N.4
Alvarez, F.5
Alfieri, C.6
-
50
-
-
0033118276
-
Kinetic selection of HPV 16 E6/ E7-directed antisense nucleic acids: Anti-proliferative effects on HPV 16-transformed cells
-
VENTURINI, F., BRASPENNING, J., HOMANN, M., GISSMANN, L., and SCZAKIEL, G. (1999). Kinetic selection of HPV 16 E6/ E7-directed antisense nucleic acids: anti-proliferative effects on HPV 16-transformed cells. Nucleic Acids Res. 27, 1585-1592.
-
(1999)
Nucleic Acids Res
, vol.27
, pp. 1585-1592
-
-
Venturini, F.1
Braspenning, J.2
Homann, M.3
Gissmann, L.4
Sczakiel, G.5
-
51
-
-
33745938741
-
Locked nucleoside analogues expand the potential of DNAzymes to cleave structured RNA targets
-
VESTER, B., HANSEN, L.H., LUNDBERG, L.B., BABU, B.R., SORENSEN, M.D., WENGEL, J., and DOUTHWAITE, S. (2006). Locked nucleoside analogues expand the potential of DNAzymes to cleave structured RNA targets. BMC. Mol. Biol. 7, 19-28.
-
(2006)
BMC. Mol. Biol.
, vol.7
, pp. 19-28
-
-
Vester, B.1
Hansen, L.H.2
Lundberg, L.B.3
Babu, B.R.4
Sorensen, M.D.5
Wengel, J.6
Douthwaite, S.7
-
52
-
-
0037145999
-
LNAzymes: Incorporation of LNA-type monomers into DNAzymes markedly increases RNA cleavage
-
VESTER, B., LUNDBERG, L.B., SORENSEN, M.D., BABU, B.R., DOUTHWAITE, S., and WENGEL, J. (2002). LNAzymes: incorporation of LNA-type monomers into DNAzymes markedly increases RNA cleavage. J. Am. Chem. Soc. 124, 13682-13683.
-
(2002)
J. Am. Chem. Soc.
, vol.124
, pp. 13682-13683
-
-
Vester, B.1
Lundberg, L.B.2
Sorensen, M.D.3
Babu, B.R.4
Douthwaite, S.5
Wengel, J.6
-
53
-
-
1442285091
-
Improved RNA cleavage by LNAzyme derivatives of DNAzymes
-
VESTER, B., LUNDBERG, L.B., SORENSEN, M.D., BABU, B.R., DOUTHWAITE, S., and WENGEL, J. (2004). Improved RNA cleavage by LNAzyme derivatives of DNAzymes. Biochem. Soc. Tra ns. 32, 37-40.
-
(2004)
Biochem. Soc. Trans.
, vol.32
, pp. 37-40
-
-
Vester, B.1
Lundberg, L.B.2
Sorensen, M.D.3
Babu, B.R.4
Douthwaite, S.5
Wengel, J.6
-
54
-
-
0034625010
-
Potent and non-toxic antisense oligonucleotides containing locked nucleic acids
-
WAHLESTEDT, C., SALMI, P., GOOD, L., KELA, J., JOHNSSON, T., HOKFELT, T., BROBERGER, C., PORRECA, F., LAI, J., REN, K., OSSIPOV, M., KOSHKIN, A., JAKOBSEN, N., SKOUV, J., OERUM, H., JACOBSEN, M.H., and WENGEL, J. (2000). Potent and non-toxic antisense oligonucleotides containing locked nucleic acids. Proc. Natl. Acad. Sci. USA. 97, 5633-5638.
-
(2000)
Proc. Natl. Acad. Sci. USA.
, vol.97
, pp. 5633-5638
-
-
Wahlestedt, C.1
Salmi, P.2
Good, L.3
Kela, J.4
Johnsson, T.5
Hokfelt, T.6
Broberger, C.7
Porreca, F.8
Lai, J.9
Ren, K.10
Ossipov, M.11
Koshkin, A.12
Jakobsen, N.13
Skouv, J.14
Oerum, H.15
Jacobsen, M.H.16
Wengel, J.17
-
55
-
-
0033117651
-
Extremely high and specif c activity of DNA enzymes in cells with a Philadelphia chromosome
-
WARASHINA, M., KUWABARA, T., NAKAMATSU, Y., and TAIRA, K. (1999). Extremely high and specif c activity of DNA enzymes in cells with a Philadelphia chromosome. Chem. Biol. 6, 237-250.
-
(1999)
Chem. Biol.
, vol.6
, pp. 237-250
-
-
Warashina, M.1
Kuwabara, T.2
Nakamatsu, Y.3
Taira, K.4
-
56
-
-
0025271203
-
Association of human papillomavirus types 16 and 18 E6 proteins with p53
-
WERNESS, B.A., LEVINE, A.J., and HOWLEY, P.M. (1990). Association of human papillomavirus types 16 and 18 E6 proteins with p53. Science. 248, 76-79.
-
(1990)
Science
, vol.248
, pp. 76-79
-
-
Werness, B.A.1
Levine, A.J.2
Howley, P.M.3
-
57
-
-
0033589752
-
Inhibition of bcr-abl oncogene expression by novel deoxyribozymes (DNAzymes
-
WU, Y., YU, L., MCMAHON, R., ROSSI, J.J., FORMAN, S.J., and SNYDER, D.S. (1999). Inhibition of bcr-abl oncogene expression by novel deoxyribozymes (DNAzymes). Hum. Gene Ther. 10, 2847-2857.
-
(1999)
Hum. Gene Ther.
, vol.10
, pp. 2847-2857
-
-
Wu, Y.1
Yu, L.2
McMahon, R.3
Rossi, J.J.4
Forman, S.J.5
Snyder, D.S.6
-
58
-
-
0037175009
-
Sequence requirements in the catalytic core of the "10-23" DNA enzyme
-
ZABOROWSKA, Z., FURSTE, J.P., ERDMANN, V.A., and KURRECK, J. (2002). Sequence requirements in the catalytic core of the "10-23" DNA enzyme. J. Biol. Chem. 277, 40617-40622.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 40617-40622
-
-
Zaborowska, Z.1
Furste, J.P.2
Erdmann, V.A.3
Kurreck, J.4
-
59
-
-
0030577120
-
Papillomavirus infections - A major cause of human cancers
-
DOI 10.1016/0304-419X(96)00020-0
-
ZUR HAUSEN, H. (1996). Papillomavirus infections a major cause of human cancers. Biochim. Biophys. Acta 1288, F55-F78. (Pubitemid 26335492)
-
(1996)
Biochimica et Biophysica Acta - Reviews on Cancer
, vol.1288
, Issue.2
-
-
Zur Hausen, H.1
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