-
1
-
-
0001593597
-
Metallothionein: A cadmium-and zinc-containing protein from equine renal cortex
-
Kagi JH, Valee BL. Metallothionein: a cadmium-and zinc-containing protein from equine renal cortex. J Biol Chem. 1960;235:3460-3465
-
(1960)
J Biol Chem
, vol.235
, pp. 3460-3465
-
-
Kagi, J.H.1
Valee, B.L.2
-
2
-
-
0022349249
-
Independence of the domains of metallothionein in metal binding
-
Nielson KB, Winge DR. Independence of the domains of metallothionein in metal binding. J Biol Chem. 1985;260:8698-8701
-
(1985)
J Biol Chem
, vol.260
, pp. 8698-8701
-
-
Nielson, K.B.1
Winge, D.R.2
-
3
-
-
0037081472
-
Dynamics of interdomain and intermolecular interactions in mammalian metal-lothioneins
-
Zangger K, Armitage IM. Dynamics of interdomain and intermolecular interactions in mammalian metal-lothioneins. J Inorg Biochem. 2002;88:135-143
-
(2002)
J Inorg Biochem
, vol.88
, pp. 135-143
-
-
Zangger, K.1
Armitage, I.M.2
-
4
-
-
0031960981
-
Mechanisms for protection against copper toxicity
-
Dameron CT, Harrison MD. Mechanisms for protection against copper toxicity. Am J Clin Nutr. 1998;67:1091S-7S.
-
(1998)
Am J Clin Nutr
, vol.67
-
-
Dameron, C.T.1
Harrison, M.D.2
-
5
-
-
0033038019
-
Regulatory role of metallothionein in NF-kappaB activation
-
Sakurai A, Hara S, Okano N, Kondo Y, Inoue J, Imura N. Regulatory role of metallothionein in NF-kappaB activation. FEBS Lett. 1999;455:55-58
-
(1999)
FEBS Lett
, vol.455
, pp. 55-58
-
-
Sakurai, A.1
Hara, S.2
Okano, N.3
Kondo, Y.4
Inoue, J.5
Imura, N.6
-
6
-
-
0038150155
-
Zinc-induced NF-kappaB inhibition can be modulated by changes in the intracellular metallothionein level
-
Kim CH, Kim JH, Lee J, Ahn YS. Zinc-induced NF-kappaB inhibition can be modulated by changes in the intracellular metallothionein level. Toxicol Appl Pharmacol. 2003;190:189-196
-
(2003)
Toxicol Appl Pharmacol
, vol.190
, pp. 189-196
-
-
Kim, C.H.1
Kim, J.H.2
Lee, J.3
Ahn, Y.S.4
-
8
-
-
0025976912
-
Tionein (apometallothionein) can modulate DNA binding and transcription activation by zinc fnger containing factor Sp1
-
Zeng J, Heuchel R, Schafner W, Kagi JH. Tionein (apometallothionein) can modulate DNA binding and transcription activation by zinc fnger containing factor Sp1. FEBS Lett. 1991;279:310-312
-
(1991)
FEBS Lett
, vol.279
, pp. 310-312
-
-
Zeng, J.1
Heuchel, R.2
Schafner, W.3
Kagi, J.H.4
-
9
-
-
0346099129
-
A role for extracellular metal-lothioneins in CNS injury and repair
-
Chung RS, West AK. A role for extracellular metal-lothioneins in CNS injury and repair. Neuroscience. 2004;123:595-599
-
(2004)
Neuroscience
, vol.123
, pp. 595-599
-
-
Chung, R.S.1
West, A.K.2
-
10
-
-
0020510944
-
Metallothionein and occupational exposure to cadmium
-
Falck FY Jr, Fine LJ, Smith RG, Garvey J, Schork A, England B, McClatchey KD, Linton J. Metallothionein and occupational exposure to cadmium. Br J Ind Med. 1983;40:305-313
-
(1983)
Br J Ind Med
, vol.40
, pp. 305-313
-
-
Jr F.Fy1
Fine, L.J.2
Smith, R.G.3
Garvey, J.4
Schork, A.5
England, B.6
McClatchey, K.D.7
Linton, J.8
-
11
-
-
33645799538
-
Te physiological roles of extracellular metallothionein
-
Lynes MA, Zafuto K, Unfricht DW, Marusov G, Samson JS, Yin X. Te physiological roles of extracellular metallothionein. Exp Biol Med (Maywood). 2006;231:1548-1554
-
(2006)
Exp Biol Med (Maywood)
, vol.231
, pp. 1548-1554
-
-
Lynes, M.A.1
Zafuto, K.2
Unfricht, D.W.3
Marusov, G.4
Samson, J.S.5
Yin, X.6
-
12
-
-
0036379353
-
Metallothionein suppresses collagen-induced arthritis via induction of TGF-beta and down-regulation of proinfammatory mediators
-
Youn J, Hwang SH, Ryoo ZY, Lynes MA, Paik DJ, Chung HS, Kim HY. Metallothionein suppresses collagen-induced arthritis via induction of TGF-beta and down-regulation of proinfammatory mediators. Clin Exp Immunol. 2002;129:232-239
-
(2002)
Clin Exp Immunol
, vol.129
, pp. 232-239
-
-
Youn, J.1
Hwang, S.H.2
Ryoo, Z.Y.3
Lynes, M.A.4
Paik, D.J.5
Chung, H.S.6
Kim, H.Y.7
-
13
-
-
19944378415
-
Role of metallothionein in antigen-related airway infammation
-
Inoue K, Takano H, Yanagisawa R, Sakurai M, Ichinose T, Sadakane K, Hiyoshi K, Sato M, Shimada A, Inoue M, Yoshikawa T. Role of metallothionein in antigen-related airway infammation. Exp Biol Med (Maywood). 2005;230:75-81.
-
(2005)
Exp Biol Med (Maywood)
, vol.230
, pp. 75-81
-
-
Inoue, K.1
Takano, H.2
Yanagisawa, R.3
Sakurai, M.4
Ichinose, T.5
Sadakane, K.6
Hiyoshi, K.7
Sato, M.8
Shimada, A.9
Inoue, M.10
Yoshikawa, T.11
-
14
-
-
9644268938
-
Protective role of metallothionein in acute lung injury induced by bacterial endotoxin
-
DOI 10.1136/thx.2004.024232
-
Takano H, Inoue K, Yanagisawa R, Sato M, Shimada A, Morita T, Sawada M, Nakamura K, Sanbongi C, Yoshikawa T. Protective role of metallothionein in acute lung injury induced by bacterial endotoxin. Torax. 2004;59:1057-1062 (Pubitemid 39573925)
-
(2004)
Thorax
, vol.59
, Issue.12
, pp. 1057-1062
-
-
Takano, H.1
Inoue, K.2
Yanagisawa, R.3
Sato, M.4
Shimada, A.5
Morita, T.6
Sawada, M.7
Nakamura, K.8
Sanbongi, C.9
Yoshikawa, T.10
-
15
-
-
0035344459
-
Nitric oxide selectively releases metals from the amino-terminal domain of metallothioneins: Potential role at infammatory sites
-
Zangger K, Oz G, Haslinger E, Kunert O, Armitage IM. Nitric oxide selectively releases metals from the amino-terminal domain of metallothioneins: potential role at infammatory sites. FASEB J. 2001;15:1303-1305
-
(2001)
FASEB J
, vol.15
, pp. 1303-1305
-
-
Zangger, K.1
Oz, G.2
Haslinger, E.3
Kunert, O.4
Armitage, I.M.5
-
16
-
-
26444577831
-
Metallothionein mediates leukocyte chemotaxis
-
Yin X, Knecht DA, Lynes MA. Metallothionein mediates leukocyte chemotaxis. BMC Immunol. 2005;6:21.
-
(2005)
BMC Immunol
, vol.6
, pp. 21
-
-
Yin, X.1
Knecht, D.A.2
Lynes, M.A.3
-
18
-
-
0031133179
-
Antisense down-regulation of metallothionein induces growth arrest and apoptosis in human breast carcinoma cells
-
Abdel-Mageed A, Agrawal KC. Antisense down-regulation of metallothionein induces growth arrest and apoptosis in human breast carcinoma cells. Cancer Gene Ter. 1997;4:199-207.
-
(1997)
Cancer Gene ter
, vol.4
, pp. 199-207
-
-
Abdel-Mageed, A.1
Agrawal, K.C.2
-
19
-
-
60549107294
-
Silencing the Metallothionein-2A gene inhibits cell cycle progression from G1-to S-phase involving ATM and cdc25A signaling in breast cancer cells
-
Lim D, Jocelyn KM, Yip GW, Bay BH. Silencing the Metallothionein-2A gene inhibits cell cycle progression from G1-to S-phase involving ATM and cdc25A signaling in breast cancer cells. Cancer Lett. 2009;276(1):109-117
-
(2009)
Cancer Lett
, vol.276
, Issue.1
, pp. 109-117
-
-
Lim, D.1
Jocelyn, K.M.2
Yip, G.W.3
Bay, B.H.4
-
20
-
-
0002599375
-
Metallothionein: Molecular evolution and classifcation
-
In: Klaassen CD, editor Basel: Birkhäuser Verlag
-
Binz PA, Kagi JHR. Metallothionein: molecular evolution and classifcation. In: Klaassen CD, editor. Metallothionein IV. Basel: Birkhäuser Verlag; 1999. p. 7-13.
-
(1999)
Metallothionein IV
, pp. 7-13
-
-
Binz, P.A.1
Kagi, J.H.R.2
-
21
-
-
0009798409
-
Human metallothionein genes are clustered on chromosome 16
-
Karin M, Eddy RL, Henry WM, Haley LL, Byers MG, Shows TB. Human metallothionein genes are clustered on chromosome 16. Proc Natl Acad Sci U S A. 1984;81:5494-5498
-
(1984)
Proc Natl Acad Sci U S A
, vol.81
, pp. 5494-5498
-
-
Karin, M.1
Eddy, R.L.2
Henry, W.M.3
Haley, L.L.4
Byers, M.G.5
Shows, T.B.6
-
22
-
-
19944419749
-
The sequence and analysis of duplication-rich human chromosome 16
-
DOI 10.1038/nature03187
-
Martin J, Han C, Gordon LA, Terry A, Prabhakar S, She X, Xie G, Hellsten U, Chan YM, Altherr M, Couronne O, Aerts A, Bajorek E, Black S, Blumer H, Branscomb E, Brown NC, Bruno WJ, Buckingham JM, Callen DF, Campbell CS, Campbell ML, Campbell EW, Caoile C, Challacombe JF, Chasteen LA, Chertkov O, Chi HC, Christensen M, Clark LM, Cohn JD, Denys M, Detter JC, Dickson M, Dimitrijevic-Bussod M, Escobar J, Fawcett JJ, Flowers D, Fotopulos D, Glavina T, Gomez M, Gonzales E, Goodstein D, Goodwin LA, Grady DL, Grigoriev I, Groza M, Hammon N, Hawkins T, Haydu L, Hildebrand CE, Huang W, Israni S, Jett J, Jewett PB, Kadner K, Kimball H, Kobayashi A, Krawczyk MC, Leyba T, Longmire JL, Lopez F, Lou Y, Lowry S, Ludeman T, Manohar CF, Mark GA, McMurray KL, Meincke LJ, Morgan J, Moyzis RK, Mundt MO, Munk AC, Nandkeshwar RD, Pitluck S, Pollard M, Predki P, Parson-Quintana B, Ramirez L, Rash S, Retterer J, Ricke DO, Robinson DL, Rodriguez A, Salamov A, Saunders EH, Scott D, Shough T, Stallings RL, Stalvey M, Sutherland RD, Tapia R, Tesmer JG, Tayer N, Tompson LS, Tice H, Torney DC, Tran-Gyamf M, Tsai M, Ulanovsky LE, Ustaszewska A, Vo N, White PS, Williams AL, Wills PL, Wu JR, Wu K, Yang J, Dejong P, Bruce D, Doggett NA, Deaven L, Schmutz J, Grimwood J, Richardson P, Rokhsar DS, Eichler EE, Gilna P, Lucas SM, Myers RM, Rubin EM, Pennacchio LA. Te sequence and analysis of duplication-rich human chromosome 16. Nature. 2004;432:988-994 (Pubitemid 40052223)
-
(2004)
Nature
, vol.432
, Issue.7020
, pp. 988-994
-
-
Martin, J.1
Han, C.2
Gordon, L.A.3
Terry, A.4
Prabhakar, S.5
She, X.6
Xie, G.7
Hellsten, U.8
Chan, Y.M.9
Altherr, M.10
Cournne, O.11
Aests, A.12
Bajorek, E.13
Black, S.14
Blumer, H.15
Branscomb, E.16
Brown, N.C.17
Bruno, W.J.18
Buckingham, J.M.19
Callen, D.F.20
Campbell, C.S.21
Campbell, M.L.22
Campbell, E.W.23
Caoile, C.24
Challacombe, J.F.25
Chasteen, L.A.26
Chertkov, O.27
Chi, H.C.28
Christensen, M.29
Clark, L.M.30
Cohn, J.D.31
Denys, M.32
Detter, J.C.33
Dickson, M.34
Dimitrijevic-Bussod, M.35
Escobar, J.36
Fawcett, J.J.37
Flowers, D.38
Fotopulos, D.39
Glavina, T.40
Gomez, M.41
Gonzales, E.42
Goodstoin, D.43
Goodwin, L.A.44
Grady, D.L.45
Grigorlev, I.46
Groza, M.47
Hammon, N.48
Hawkins, T.49
Haydu, L.50
Hildebrand, C.E.51
Huang, W.52
Israni, S.53
Jett, J.54
Jewott, P.B.55
Kadner, K.56
Kimball, H.57
Kobayashi, A.58
Krawczyk, M.-C.59
Leyba, T.60
Longmire, J.L.61
Lopez, F.62
Lou, Y.63
Lowry, S.64
Ludeman, T.65
Manohar, C.F.66
Mark, G.A.67
McMurray, K.L.68
Meincke, L.J.69
Morgan, J.70
Moyzis, R.K.71
Mundt, M.O.72
Munk, A.C.73
Handkeshwar, R.D.74
Pitluck, S.75
Pollard, M.76
Predki, P.77
Parson-Quintana, B.78
Ramirez, L.79
Rash, S.80
Retterer, J.81
Ricke, D.O.82
Robinson, D.L.83
Rodgriguez, A.84
Salamov, A.85
Saunders, E.H.86
Scott, D.87
Shough, T.88
Stallings, R.L.89
Stalvey, M.90
Sutherland, R.D.91
Tapla, R.92
Tesmer, J.G.93
Thayer, H.94
Thompson, L.D.95
Tice, H.96
more..
-
23
-
-
0021885286
-
Structure and expression of two human metallothionein-I iso-form genes and a related pseudogene
-
Schmidt CJ, Jubier MF, Hamer DH. Structure and expression of two human metallothionein-I iso-form genes and a related pseudogene. J Biol Chem. 1985;260:7731-7737
-
(1985)
J Biol Chem
, vol.260
, pp. 7731-7737
-
-
Schmidt, C.J.1
Jubier, M.F.2
Hamer, D.H.3
-
24
-
-
33751437558
-
Zinc-binding proteins (metal-lothionein and alpha-2 macroglobulin) and immunose-nescence
-
Mocchegiani E, Costarelli L, Giacconi R, Cipriano C, Muti E, Malavolta M. Zinc-binding proteins (metal-lothionein and alpha-2 macroglobulin) and immunose-nescence. Exp Gerontol. 2006;41:1094-1107
-
(2006)
Exp Gerontol
, vol.41
, pp. 1094-1107
-
-
Mocchegiani, E.1
Costarelli, L.2
Giacconi, R.3
Cipriano, C.4
Muti, E.5
Malavolta, M.6
-
25
-
-
0032956288
-
Expression of MT-3 protein in the human kidney
-
Garrett SH, Sens MA, Todd JH, Somji S, Sens DA. Expression of MT-3 protein in the human kidney. Toxicol Lett. 1999;105:207-214
-
(1999)
Toxicol Lett
, vol.105
, pp. 207-214
-
-
Garrett, S.H.1
Sens, M.A.2
Todd, J.H.3
Somji, S.4
Sens, D.A.5
-
26
-
-
0028009502
-
Distribution of metallo-thionein in normal and pathological human skin
-
van den Oord JJ, De Ley M. Distribution of metallo-thionein in normal and pathological human skin. Arch Dermatol Res. 1994;286:62-68
-
(1994)
Arch Dermatol Res
, vol.286
, pp. 62-68
-
-
Van Den Oord, J.J.1
De Ley, M.2
-
27
-
-
13844297727
-
Prognostic signifcance of metallothionein expression in renal cell carcinoma
-
Mitropoulos D, Kyroudi-Voulgari A, Teocharis S, Serafetinides E, Moraitis E, Zervas A, Kittas C. Prognostic signifcance of metallothionein expression in renal cell carcinoma. World J Surg Oncol. 2005;3:5.
-
(2005)
World J Surg Oncol
, vol.3
, pp. 5
-
-
Mitropoulos, D.1
Kyroudi-Voulgari, A.2
Teocharis, S.3
Serafetinides, E.4
Moraitis, E.5
Zervas, A.6
Kittas, C.7
-
28
-
-
0033983806
-
Immunocytochemical localization of metallothionein in human pancreatic islets
-
Tomita T, Matsubara O. Immunocytochemical localization of metallothionein in human pancreatic islets. Pancreas. 2000;20:21-24
-
(2000)
Pancreas
, vol.20
, pp. 21-24
-
-
Tomita, T.1
Matsubara, O.2
-
29
-
-
0025312740
-
Age-related changes in metallothionein, copper, copper-associated protein, and lipofuscin in human liver: A histochemical and immu-nohistochemical study
-
Fuller CE, Elmes ME, Jasani B. Age-related changes in metallothionein, copper, copper-associated protein, and lipofuscin in human liver: a histochemical and immu-nohistochemical study. J Pathol. 1990;161:167-172
-
(1990)
J Pathol
, vol.161
, pp. 167-172
-
-
Fuller, C.E.1
Elmes, M.E.2
Jasani, B.3
-
30
-
-
33644628881
-
Serum-induced expression of metallothionein isoforms in K-562 cells
-
Kuppens K, De Ley M. Serum-induced expression of metallothionein isoforms in K-562 cells. Biochem Biophys Res Commun. 2006;342:979-983
-
(2006)
Biochem Biophys Res Commun
, vol.342
, pp. 979-983
-
-
Kuppens, K.1
De Ley, M.2
-
31
-
-
70349901871
-
Reduced metallothi-onein expression in colonic Crohn's disease: Evidence for a new disease-modifying gene
-
Laukens D, Peeters H, Waeytens A, Bogaert S, Vander Cruyssen B, Elewaut D, et al. Reduced metallothi-onein expression in colonic Crohn's disease: evidence for a new disease-modifying gene. Gastroenterology. 2008;134:A-457.
-
(2008)
Gastroenterology
, vol.134
-
-
Laukens, D.1
Peeters, H.2
Waeytens, A.3
Bogaert, S.4
Vander Cruyssen, B.5
Elewaut, D.6
-
32
-
-
0033918676
-
Crypt-restricted metallothionein immunopositivity in murine colon: Validation of a model for studies of somatic stem cell mutation
-
Anne Cook H, Williams D, Anne Tomas G. Crypt-restricted metallothionein immunopositivity in murine colon: validation of a model for studies of somatic stem cell mutation. J Pathol. 2000;191:306-312
-
(2000)
J Pathol
, vol.191
, pp. 306-312
-
-
Anne Cook, H.1
Williams, D.2
Anne Tomas, G.3
-
33
-
-
0023013613
-
Te immunocyto-chemical demonstration of metallothionein in human liver and small intestine
-
Elmes ME, Clarkson JP, Jasani B. Te immunocyto-chemical demonstration of metallothionein in human liver and small intestine. Acta Pharmacol Toxicol (Copenh). 1986;59:510-513
-
(1986)
Acta Pharmacol Toxicol (Copenh)
, vol.59
, pp. 510-513
-
-
Elmes, M.E.1
Clarkson, J.P.2
Jasani, B.3
-
34
-
-
0022363039
-
Histological demonstration of immunoreactive zinc metallothi-onein in liver and ileum of rat and man
-
Clarkson JP, Elmes ME, Jasani B, Webb M. Histological demonstration of immunoreactive zinc metallothi-onein in liver and ileum of rat and man. Histochem J. 1985;17:343-352
-
(1985)
Histochem J
, vol.17
, pp. 343-352
-
-
Clarkson, J.P.1
Elmes, M.E.2
Jasani, B.3
Webb, M.4
-
35
-
-
0037217176
-
Te immunohistochemical expression of metal-lothionein in infammatory bowel disease. Correlation with HLA-DR antigen expression, lymphocyte sub-populations and proliferation-associated indices
-
Ioachim E, Michael M, Katsanos C, Demou A, Tsianos EV. Te immunohistochemical expression of metal-lothionein in infammatory bowel disease. Correlation with HLA-DR antigen expression, lymphocyte sub-populations and proliferation-associated indices. Histol Histopathol. 2003;18:75-82.
-
(2003)
Histol Histopathol
, vol.18
, pp. 75-82
-
-
Ioachim, E.1
Michael, M.2
Katsanos, C.3
Demou, A.4
Tsianos, E.V.5
-
36
-
-
0141563440
-
Imbalanced secondary mucosal antioxidant response in infammatory bowel disease
-
Kruidenier L, Kuiper I, Van Duijn W, Mieremet-Ooms MA, van Hogezand RA, Lamers CB, Verspaget HW. Imbalanced secondary mucosal antioxidant response in infammatory bowel disease. J Pathol. 2003;201:17-27.
-
(2003)
J Pathol
, vol.201
, pp. 17-27
-
-
Kruidenier, L.1
Kuiper, I.2
Van Duijn, W.3
Mieremet-Ooms, M.A.4
Van Hogezand, R.A.5
Lamers, C.B.6
Verspaget, H.W.7
-
37
-
-
0034964640
-
Increased expression of metallothionein in infammatory bowel disease
-
Bruwer M, Schmid KW, Metz KA, Krieglstein CF, Senninger N, Schurmann G. Increased expression of metallothionein in infammatory bowel disease. Infamm Res. 2001;50:289-293
-
(2001)
Infamm Res
, vol.50
, pp. 289-293
-
-
Bruwer, M.1
Schmid, K.W.2
Metz, K.A.3
Krieglstein, C.F.4
Senninger, N.5
Schurmann, G.6
-
38
-
-
0347286902
-
Regulation of gene expression in infammatory bowel disease and correlation with IBD drugs: Screening by DNA microarrays
-
Dooley TP, Curto EV, Reddy SP, Davis RL, Lambert GW, Wilborn TW, Elson CO. Regulation of gene expression in infammatory bowel disease and correlation with IBD drugs: screening by DNA microarrays. Infamm Bowel Dis. 2004;10:1-14.
-
(2004)
Infamm Bowel Dis
, vol.10
, pp. 1-14
-
-
Dooley, T.P.1
Curto, E.V.2
Reddy, S.P.3
Davis, R.L.4
Lambert, G.W.5
Wilborn, T.W.6
Elson, C.O.7
-
39
-
-
0026075996
-
Decrease in two intestinal copper/ zinc containing proteins with antioxidant function in infammatory bowel disease
-
Mulder TP, Verspaget HW, Janssens AR, de Bruin PA, Pena AS, Lamers CB. Decrease in two intestinal copper/ zinc containing proteins with antioxidant function in infammatory bowel disease. Gut. 1991;32:1146-1150
-
(1991)
Gut
, vol.32
, pp. 1146-1150
-
-
Mulder, T.P.1
Verspaget, H.W.2
Janssens, A.R.3
De Bruin, P.A.4
Pena, A.S.5
Lamers, C.B.6
-
40
-
-
0035282710
-
Ulcerative colitis and Crohn's disease: Distinctive gene expression profles and novel susceptibility candidate genes
-
Lawrance IC, Fiocchi C, Chakravarti S. Ulcerative colitis and Crohn's disease: distinctive gene expression profles and novel susceptibility candidate genes. Hum Mol Genet. 2001;10:445-456
-
(2001)
Hum Mol Genet
, vol.10
, pp. 445-456
-
-
Lawrance, I.C.1
Fiocchi, C.2
Chakravarti, S.3
-
41
-
-
14444278962
-
Altered plasma and mucosal concentrations of trace elements and antioxidants in active ulcerative colitis
-
Sturniolo GC, Mestriner C, Lecis PE, D'Odorico A, Venturi C, Irato P, Cecchetto A, Tropea A, Longo G, D'Inca R. Altered plasma and mucosal concentrations of trace elements and antioxidants in active ulcerative colitis. Scand J Gastroenterol. 1998;33:644-649
-
(1998)
Scand J Gastroenterol
, vol.33
, pp. 644-649
-
-
Sturniolo, G.C.1
Mestriner, C.2
Lecis, P.E.3
D'Odorico, A.4
Venturi, C.5
Irato, P.6
Cecchetto, A.7
Tropea, A.8
Longo, G.9
D'Inca, R.10
-
42
-
-
1842455329
-
Genetics of infammatory bowel disease: Progress and prospects
-
Mathew CG, Lewis CM. Genetics of infammatory bowel disease: progress and prospects. Hum Mol Genet. 2004;13 Spec No 1:R161-8.
-
(2004)
Hum Mol Genet
, vol.13
, Issue.SPEC 1
-
-
Mathew, C.G.1
Lewis, C.M.2
-
43
-
-
33846138032
-
Te role of microbes in Crohn's disease
-
Eckburg PB, Relman DA. Te role of microbes in Crohn's disease. Clin Infect Dis. 2007;44:256-262
-
(2007)
Clin Infect Dis
, vol.44
, pp. 256-262
-
-
Eckburg, P.B.1
Relman, D.A.2
-
44
-
-
0036310491
-
Metallothioneins: Potential therapeutic aids for wound healing in the skin
-
Lansdown AB. Metallothioneins: potential therapeutic aids for wound healing in the skin. Wound Repair Regen. 2002;10:130-132
-
(2002)
Wound Repair Regen
, vol.10
, pp. 130-132
-
-
Lansdown, A.B.1
-
45
-
-
25644456042
-
Cellular and molecular mechanisms of the epithelial repair in IBD
-
Okamoto R, Watanabe M. Cellular and molecular mechanisms of the epithelial repair in IBD. Dig Dis Sci. 2005;50(Suppl 1):S34-8.
-
(2005)
Dig Dis Sci
, vol.50
, Issue.SUPPL. 1
-
-
Okamoto, R.1
Watanabe, M.2
-
46
-
-
15944383761
-
Metallothionein overexpression does not protect against infammatory bowel disease in a murine colitis model
-
Oz HS, Chen T, de Villiers WJ, McClain CJ. Metallothionein overexpression does not protect against infammatory bowel disease in a murine colitis model. Med Sci Monit. 2005;11:BR69-73.
-
(2005)
Med Sci Monit
, vol.11
-
-
Oz, H.S.1
Chen, T.2
De Villiers, W.J.3
McClain, C.J.4
-
47
-
-
34547843593
-
Te role of zinc and metallothionein in the dextran sulfate sodium-induced colitis mouse model
-
Tran CD, Ball JM, Sundar S, Coyle P, Howarth GS. Te role of zinc and metallothionein in the dextran sulfate sodium-induced colitis mouse model. Dig Dis Sci. 2007;52:2113-2121
-
(2007)
Dig Dis Sci
, vol.52
, pp. 2113-2121
-
-
Tran, C.D.1
Ball, J.M.2
Sundar, S.3
Coyle, P.4
Howarth, G.S.5
-
49
-
-
0034900646
-
Dietary zinc defciency and repletion modulate metallothionein immunolocalization and concentration in small intestine and liver of rats
-
Szczurek EI, Bjornsson CS, Taylor CG. Dietary zinc defciency and repletion modulate metallothionein immunolocalization and concentration in small intestine and liver of rats. J Nutr. 2001;131:2132-2138
-
(2001)
J Nutr
, vol.131
, pp. 2132-2138
-
-
Szczurek, E.I.1
Bjornsson, C.S.2
Taylor, C.G.3
-
50
-
-
0032786934
-
Regional distribution and localization of zinc and metallothionein in the intestine of rats fed diets difering in zinc content
-
Tran CD, Butler RN, Howarth GS, Philcox JC, Rofe AM, Coyle P. Regional distribution and localization of zinc and metallothionein in the intestine of rats fed diets difering in zinc content. Scand J Gastroenterol. 1999;34:689-695
-
(1999)
Scand J Gastroenterol
, vol.34
, pp. 689-695
-
-
Tran, C.D.1
Butler, R.N.2
Howarth, G.S.3
Philcox, J.C.4
Rofe, A.M.5
Coyle, P.6
-
51
-
-
0028148507
-
Efect of oral zinc supplementation on metallothionein and superoxide dismutase concentrations in patients with infammatory bowel disease
-
Mulder TP, van der Sluys Veer A, Verspaget HW, Grifoen G, Pena AS, Janssens AR, Lamers CB. Efect of oral zinc supplementation on metallothionein and superoxide dismutase concentrations in patients with infammatory bowel disease. J Gastroenterol Hepatol. 1994;9:472-477
-
(1994)
J Gastroenterol Hepatol
, vol.9
, pp. 472-477
-
-
Mulder, T.P.1
Van Der Sluys Veer, A.2
Verspaget, H.W.3
Grifoen, G.4
Pena, A.S.5
Janssens, A.R.6
Lamers, C.B.7
-
52
-
-
32444433605
-
Te role of MT in neurological disorders
-
discussion 209-215
-
Aschner M, West AK. Te role of MT in neurological disorders. J Alzheimers Dis. 2005;8:139-45; discussion 209-215
-
(2005)
J Alzheimers Dis
, vol.8
, pp. 139-145
-
-
Aschner, M.1
West, A.K.2
-
53
-
-
0027048685
-
Molecular cloning of human growth inhibitory factor cDNA and its down-regulation in Alzheimer's disease
-
Tsuji S, Kobayashi H, Uchida Y, Ihara Y, Miyatake T. Molecular cloning of human growth inhibitory factor cDNA and its down-regulation in Alzheimer's disease. EMBO J. 1992;11:4843-4850
-
(1992)
EMBO J
, vol.11
, pp. 4843-4850
-
-
Tsuji, S.1
Kobayashi, H.2
Uchida, Y.3
Ihara, Y.4
Miyatake, T.5
-
54
-
-
0035831110
-
Metallothionein III is reduced in Alzheimer's disease
-
Yu WH, Lukiw WJ, Bergeron C, Niznik HB, Fraser PE. Metallothionein III is reduced in Alzheimer's disease. Brain Res. 2001;894:37-45.
-
(2001)
Brain Res
, vol.894
, pp. 37-45
-
-
Yu, W.H.1
Lukiw, W.J.2
Bergeron, C.3
Niznik, H.B.4
Fraser, P.E.5
-
55
-
-
0037010289
-
Gene expression profling of 12633 genes in Alzheimer hippocampal CA1: Transcription and neurotrophic factor down-regulation and up-regulation of apoptotic and pro-infammatory signaling
-
Colangelo V, Schurr J, Ball MJ, Pelaez RP, Bazan NG, Lukiw WJ. Gene expression profling of 12633 genes in Alzheimer hippocampal CA1: transcription and neurotrophic factor down-regulation and up-regulation of apoptotic and pro-infammatory signaling. J Neurosci Res. 2002;70:462-473
-
(2002)
J Neurosci Res
, vol.70
, pp. 462-473
-
-
Colangelo, V.1
Schurr, J.2
Ball, M.J.3
Pelaez, R.P.4
Bazan, N.G.5
Lukiw, W.J.6
-
56
-
-
0028263925
-
Enhanced neurotrophic activity in Alzheimer's disease cortex is not associated with down-regulation of metallothionein-III (GIF)
-
Erickson JC, Sewell AK, Jensen LT, Winge DR, Palmiter RD. Enhanced neurotrophic activity in Alzheimer's disease cortex is not associated with down-regulation of metallothionein-III (GIF). Brain Res. 1994;649:297-304.
-
(1994)
Brain Res
, vol.649
, pp. 297-304
-
-
Erickson, J.C.1
Sewell, A.K.2
Jensen, L.T.3
Winge, D.R.4
Palmiter, R.D.5
-
57
-
-
0032413587
-
Increased density of metallothionein I/II-immunopositive cortical glial cells in the early stages of Alzheimer's disease
-
Adlard PA, West AK, Vickers JC. Increased density of metallothionein I/II-immunopositive cortical glial cells in the early stages of Alzheimer's disease. Neurobiol Dis. 1998;5:349-356
-
(1998)
Neurobiol Dis
, vol.5
, pp. 349-356
-
-
Adlard, P.A.1
West, A.K.2
Vickers, J.C.3
-
58
-
-
0346457011
-
Neuron-glia communication: Metal-lothionein expression is specifcally up-regulated by astrocytes in response to neuronal injury
-
Chung RS, Adlard PA, Dittmann J, Vickers JC, Chuah MI, West AK. Neuron-glia communication: metal-lothionein expression is specifcally up-regulated by astrocytes in response to neuronal injury. J Neurochem. 2004;88:454-461
-
(2004)
J Neurochem
, vol.88
, pp. 454-461
-
-
Chung, R.S.1
Adlard, P.A.2
Dittmann, J.3
Vickers, J.C.4
Chuah, M.I.5
West, A.K.6
-
59
-
-
0032127594
-
Metallothioneins are highly expressed in astrocytes and microcapil-laries in Alzheimer's disease
-
Zambenedetti P, Giordano R, Zatta P. Metallothioneins are highly expressed in astrocytes and microcapil-laries in Alzheimer's disease. J Chem Neuroanat. 1998;15:21-26
-
(1998)
J Chem Neuroanat
, vol.15
, pp. 21-26
-
-
Zambenedetti, P.1
Giordano, R.2
Zatta, P.3
-
61
-
-
33749620702
-
Expression of metallothionein-I, -II, and -III in Alzheimer disease and animal models of neuroinflammation
-
Hidalgo J, Penkowa M, Espejo C, Martinez-Caceres EM, Carrasco J, Quintana A, Molinero A, Florit S, Giralt M, Ortega-Aznar A. Expression of metallothionein-I,-II, and-III in Alzheimer disease and animal models of neuroinfammation. Exp Biol Med (Maywood). 2006;231:1450-1458 (Pubitemid 44547836)
-
(2006)
Experimental Biology and Medicine
, vol.231
, Issue.9
, pp. 1450-1458
-
-
Hidalgo, J.1
Penkowa, M.2
Espejo, C.3
Martinez-Caceres, E.M.4
Carrasco, J.5
Quintana, A.6
Molinero, A.7
Florit, S.8
Giralt, M.9
Ortega-Aznar, A.10
-
62
-
-
33646268801
-
Metallothioneins are multipurpose neu-roprotectants during brain pathology
-
Penkowa M. Metallothioneins are multipurpose neu-roprotectants during brain pathology. FEBS Journal. 2006;273:1857-1870
-
(2006)
FEBS Journal
, vol.273
, pp. 1857-1870
-
-
Penkowa, M.1
-
63
-
-
0028138473
-
Metallothionein in amyotrophic lateral sclerosis
-
Sillevis Smitt PA, Mulder T P, Verspaget HW, Blaauwgeers HG, Troost D, de Jong JM. Metallothionein in amyotrophic lateral sclerosis. Biol Signals. 1994; 3:193-197
-
(1994)
Biol Signals
, vol.3
, pp. 193-197
-
-
Sillevis Smitt, P.A.1
Mulder, T.P.2
Verspaget, H.W.3
Blaauwgeers, H.G.4
Troost, D.5
De Jong, J.M.6
-
64
-
-
0026653750
-
Increased metallothionein in the liver and kidney of patients with amyotrophic lateral sclerosis
-
Sillevis Smitt PA, van Beek H, Baars AJ, Troost D, Louwerse ES, Krops-Hermus AC, de Wolf FA, de Jong JM. Increased metallothionein in the liver and kidney of patients with amyotrophic lateral sclerosis. Arch Neurol. 1992;49:721-724
-
(1992)
Arch Neurol
, vol.49
, pp. 721-724
-
-
Sillevis Smitt, P.A.1
Van Beek, H.2
Baars, A.J.3
Troost, D.4
Louwerse, E.S.5
Krops-Hermus, A.C.6
De Wolf, F.A.7
De Jong, J.M.8
-
65
-
-
0026781415
-
Metallothionein immunoreactivity is increased in the spinal cord of patients with amyotrophic lateral sclerosis
-
Sillevis Smitt PA, Blaauwgeers HG, Troost D, de Jong JM. Metallothionein immunoreactivity is increased in the spinal cord of patients with amyotrophic lateral sclerosis. Neurosci Lett. 1992;144:107-110
-
(1992)
Neurosci Lett
, vol.144
, pp. 107-110
-
-
Sillevis Smitt, P.A.1
Blaauwgeers, H.G.2
Troost, D.3
De Jong, J.M.4
-
66
-
-
0030272622
-
Expression of diferent metallothionein messenger ribonucleic acids in motor cortex, spinal cord and liver from patients with amyo-trophic lateral sclerosis
-
Blaauwgeers HG, Anwar Chand M, van den Berg FM, Vianney de Jong JM, Troost D. Expression of diferent metallothionein messenger ribonucleic acids in motor cortex, spinal cord and liver from patients with amyo-trophic lateral sclerosis. J Neurol Sci. 1996;142:39-44.
-
(1996)
J Neurol Sci
, vol.142
, pp. 39-44
-
-
Blaauwgeers, H.G.1
Anwar Chand, M.2
Van Den Berg, F.M.3
Vianney De Jong, J.M.4
Troost, D.5
-
67
-
-
0011392304
-
Metallothionein expression is altered in a transgenic murine model of familial amyo-trophic lateral sclerosis
-
Gong YH, Elliott JL. Metallothionein expression is altered in a transgenic murine model of familial amyo-trophic lateral sclerosis. Exp Neurol. 2000;162:27-36.
-
(2000)
Exp Neurol
, vol.162
, pp. 27-36
-
-
Gong, Y.H.1
Elliott, J.L.2
-
68
-
-
0035058876
-
Reduction of metallothioneins promotes the disease expression of familial amyotrophic lateral sclerosis mice in a dose-dependent manner
-
Nagano S, Satoh M, Sumi H, Fujimura H, Tohyama C, Yanagihara T, Sakoda S. Reduction of metallothioneins promotes the disease expression of familial amyotrophic lateral sclerosis mice in a dose-dependent manner. Eur J Neurosci. 2001;13:1363-1370
-
(2001)
Eur J Neurosci
, vol.13
, pp. 1363-1370
-
-
Nagano, S.1
Satoh, M.2
Sumi, H.3
Fujimura, H.4
Tohyama, C.5
Yanagihara, T.6
Sakoda, S.7
-
69
-
-
0028964642
-
Menkes disease
-
Bankier A. Menkes disease. J Med Genet. 1995;32:213-215
-
(1995)
J Med Genet
, vol.32
, pp. 213-215
-
-
Bankier, A.1
-
70
-
-
0027446365
-
Isolation of a candidate gene for Menkes disease and evidence that it encodes a copper-transporting ATPase
-
Vulpe C, Levinson B, Whitney S, Packman S, Gitschier J. Isolation of a candidate gene for Menkes disease and evidence that it encodes a copper-transporting ATPase. Nat Genet. 1993;3:7-13.
-
(1993)
Nat Genet
, vol.3
, pp. 7-13
-
-
Vulpe, C.1
Levinson, B.2
Whitney, S.3
Packman, S.4
Gitschier, J.5
-
71
-
-
0027500142
-
Isolation of a candidate gene for Menkes disease that encodes a potential heavy metal binding protein
-
Chelly J, Tumer Z, Tonnesen T, Petterson A, Ishikawa-Brush Y, Tommerup N, Horn N, Monaco AP. Isolation of a candidate gene for Menkes disease that encodes a potential heavy metal binding protein. Nat Genet. 1993;3:14-19
-
(1993)
Nat Genet
, vol.3
, pp. 14-19
-
-
Chelly, J.1
Tumer, Z.2
Tonnesen, T.3
Petterson, A.4
Ishikawa-Brush, Y.5
Tommerup, N.6
Horn, N.7
Monaco, A.P.8
-
72
-
-
0027475976
-
Isolation of a partial candidate gene for Menkes disease by positional cloning
-
Mercer JF, Livingston J, Hall B, Paynter JA, Begy C, Chandrasekharappa S, Lockhart P, Grimes A, Bhave M, Siemieniak D, Glover TW. Isolation of a partial candidate gene for Menkes disease by positional cloning. Nat Genet. 1993;3:20-25
-
(1993)
Nat Genet
, vol.3
, pp. 20-25
-
-
Mercer, J.F.1
Livingston, J.2
Hall, B.3
Paynter, J.A.4
Begy, C.5
Chandrasekharappa, S.6
Lockhart, P.7
Grimes, A.8
Bhave, M.9
Siemieniak, D.10
Glover, T.W.11
-
73
-
-
0032769447
-
Molecular genetics and pathophysiology of Menkes disease
-
Kodama H, Murata Y. Molecular genetics and pathophysiology of Menkes disease. Pediatr Int. 1999;41:430-435
-
(1999)
Pediatr Int
, vol.41
, pp. 430-435
-
-
Kodama, H.1
Murata, Y.2
-
74
-
-
0023203028
-
Metallothionein gene regulation in Menkes' syndrome
-
Hamer DH. Metallothionein gene regulation in Menkes' syndrome. Arch Dermatol. 1987;123:1384a-5a.
-
(1987)
Arch Dermatol
, vol.123
-
-
Hamer, D.H.1
-
75
-
-
0021279259
-
Chromosomal location of human metallothionein genes: Implications for Menkes' disease
-
Schmidt CJ, Hamer DH, McBride OW. Chromosomal location of human metallothionein genes: implications for Menkes' disease. Science. 1984;224:1104-1106
-
(1984)
Science
, vol.224
, pp. 1104-1106
-
-
Schmidt, C.J.1
Hamer, D.H.2
McBride, O.W.3
-
76
-
-
0018103340
-
Role of metal-lothioneins in copper transport in patients with Menkes syndrome
-
Garnica AD, Chan WY, Rennert OM. Role of metal-lothioneins in copper transport in patients with Menkes syndrome. Ann Clin Lab Sci. 1978;8:302-309
-
(1978)
Ann Clin Lab Sci
, vol.8
, pp. 302-309
-
-
Garnica, A.D.1
Chan, W.Y.2
Rennert, O.M.3
-
77
-
-
70349922444
-
Paradigm shift in treatment of Wilson's disease: Zinc therapy now treatment of choice
-
Hoogenraad TU. Paradigm shift in treatment of Wilson's disease: Zinc therapy now treatment of choice. Brain Dev. 2006;5:5.
-
(2006)
Brain Dev
, vol.5
, pp. 5
-
-
Hoogenraad, T.U.1
-
78
-
-
0030154445
-
Stress proteins as agents of immunological change: Some lessons from metallothi-onein
-
Borghesi LA, Lynes MA. Stress proteins as agents of immunological change: some lessons from metallothi-onein. Cell Stress Chaperones. 1996;1:99-108.
-
(1996)
Cell Stress Chaperones
, vol.1
, pp. 99-108
-
-
Borghesi, L.A.1
Lynes, M.A.2
-
80
-
-
0031818254
-
Expression of the gene encoding metallothionein-3 in organs of the reproductive system
-
Mofatt P, Seguin C. Expression of the gene encoding metallothionein-3 in organs of the reproductive system. DNA Cell Biol. 1998;17:501-510
-
(1998)
DNA Cell Biol
, vol.17
, pp. 501-510
-
-
Mofatt, P.1
Seguin, C.2
-
81
-
-
0035996278
-
Expression of met-allothionein isoforms in human chorioretinal complex
-
Tate DJ, Miceli MV, Newsome DA. Expression of met-allothionein isoforms in human chorioretinal complex. Curr Eye Res. 2002;24:12-25.
-
(2002)
Curr Eye Res
, vol.24
, pp. 12-25
-
-
Tate, D.J.1
Miceli, M.V.2
Newsome, D.A.3
-
82
-
-
11244270832
-
Expression of neuronal growth inhibitory factor (metallothionein-III) in the salivary gland
-
Irie Y, Mori F, Keung WM, Mizushima Y, Wakabayashi K. Expression of neuronal growth inhibitory factor (metallothionein-III) in the salivary gland. Physiol Res. 2004;53:719-723
-
(2004)
Physiol Res
, vol.53
, pp. 719-723
-
-
Irie, Y.1
Mori, F.2
Keung, W.M.3
Mizushima, Y.4
Wakabayashi, K.5
-
83
-
-
0036602802
-
Metallothionein isoform 3 expression inhibits cell growth and increases drug resistance of PC-3 prostate cancer cells
-
Dutta R, Sens DA, Somji S, Sens MA, Garrett SH, Shukla D. Metallothionein isoform 3 expression inhibits cell growth and increases drug resistance of PC-3 prostate cancer cells. Prostate. 2002;52:89-97.
-
(2002)
Prostate
, vol.52
, pp. 89-97
-
-
Dutta, R.1
Sens, D.A.2
Somji, S.3
Sens, M.A.4
Garrett, S.H.5
Shukla, D.6
-
84
-
-
0027048685
-
Molecular cloning of human growth inhibitory factor cDNA and its down-regulation in Alzheimer's disease
-
Tsuji S, Kobayashi H, Uchida Y, Ihara Y, Miyatake T. Molecular cloning of human growth inhibitory factor cDNA and its down-regulation in Alzheimer's disease. EMBO J. 1992;11:4843-4850
-
(1992)
EMBO J
, vol.11
, pp. 4843-4850
-
-
Tsuji, S.1
Kobayashi, H.2
Uchida, Y.3
Ihara, Y.4
Miyatake, T.5
-
85
-
-
0030802387
-
Expression of MT-3 mRNA in human kidney, proximal tubule cell cultures, and renal cell carcinoma
-
Hoey JG, Garrett SH, Sens MA, Todd JH, Sens DA. Expression of MT-3 mRNA in human kidney, proximal tubule cell cultures, and renal cell carcinoma. Toxicol Lett. 1997;92:149-160
-
(1997)
Toxicol Lett
, vol.92
, pp. 149-160
-
-
Hoey, J.G.1
Garrett, S.H.2
Sens, M.A.3
Todd, J.H.4
Sens, D.A.5
-
86
-
-
0028289610
-
Induction of a new metallothionein isoform (MT-IV) occurs during difer-entiation of stratifed squamous epithelia
-
Quaife CJ, Findley SD, Erickson JC, Froelick GJ, Kelly EJ, Zambrowicz BP, Palmiter RD. Induction of a new metallothionein isoform (MT-IV) occurs during difer-entiation of stratifed squamous epithelia. Biochemistry. 1994;33:7250-7259
-
(1994)
Biochemistry
, vol.33
, pp. 7250-7259
-
-
Quaife, C.J.1
Findley, S.D.2
Erickson, J.C.3
Froelick, G.J.4
Kelly, E.J.5
Zambrowicz, B.P.6
Palmiter, R.D.7
-
87
-
-
85036774870
-
-
Liang L, Fu K, Lee DK, Sobieski RJ, Dalton T, Andrews GK. Activation of the complete mouse metallothionein
-
Activation of the complete mouse metallothionein
-
-
Liang, L.1
Fu, K.2
Lee, D.K.3
Sobieski, R.J.4
Dalton, T.5
Andrews, G.K.6
-
88
-
-
0022447163
-
Cell specifcity and an efect of ras on human metallothionein gene expression
-
Schmidt CJ, Hamer DH. Cell specifcity and an efect of ras on human metallothionein gene expression. Proc Natl Acad Sci U S A. 1986;83:3346-3350
-
(1986)
Proc Natl Acad Sci U S A
, vol.83
, pp. 3346-3350
-
-
Schmidt, C.J.1
Hamer, D.H.2
-
89
-
-
0022648524
-
Structure, organization, and regulation of human metallothionein if gene: Diferential and cell-type-specifc expression in response to heavy metals and glucocorticoids
-
Varshney U, Jahroudi N, Foster R, Gedamu L. Structure, organization, and regulation of human metallothionein IF gene: diferential and cell-type-specifc expression in response to heavy metals and glucocorticoids. Mol Cell Biol. 1986;6:26-37.
-
(1986)
Mol Cell Biol
, vol.6
, pp. 26-37
-
-
Varshney, U.1
Jahroudi, N.2
Foster, R.3
Gedamu, L.4
-
90
-
-
0021724845
-
Regulation, linkage, and sequence of mouse metallothionein i and II genes
-
Searle PF, Davison BL, Stuart GW, Wilkie TM, Norstedt G, Palmiter RD. Regulation, linkage, and sequence of mouse metallothionein I and II genes. Mol Cell Biol. 1984;4:1221-1230
-
(1984)
Mol Cell Biol
, vol.4
, pp. 1221-1230
-
-
Searle, P.F.1
Davison, B.L.2
Stuart, G.W.3
Wilkie, T.M.4
Norstedt, G.5
Palmiter, R.D.6
-
91
-
-
70349903935
-
A distance diference matrix approach to the identifcation of transcription factors that regulate diferential gene expression in higher eukaryotes
-
De Bleser P, Vlieghe D, Van Roy F. A distance diference matrix approach to the identifcation of transcription factors that regulate diferential gene expression in higher eukaryotes. Genome Research. 2006
-
(2006)
Genome Research
-
-
De Bleser, P.1
Vlieghe, D.2
Van Roy, F.3
-
92
-
-
0023071218
-
Structure and expression of the human metallothi-onein genes
-
Gedamu L, Varshney U, Jahroudi N, Foster R, Shworak NW. Structure and expression of the human metallothi-onein genes. Experientia Suppl. 1987;52:361-372
-
(1987)
Experientia Suppl
, vol.52
, pp. 361-372
-
-
Gedamu, L.1
Varshney, U.2
Jahroudi, N.3
Foster, R.4
Shworak, N.W.5
-
93
-
-
0027435262
-
Distinct TATA motifs regulate diferential expression of human metallothionein i genes MT-IF and MT-IG
-
Shworak NW, O'Connor T, Wong NC, Gedamu L. Distinct TATA motifs regulate diferential expression of human metallothionein I genes MT-IF and MT-IG. J Biol Chem. 1993;268:24460-24466
-
(1993)
J Biol Chem
, vol.268
, pp. 24460-24466
-
-
Shworak, N.W.1
O'Connor, T.2
Wong, N.C.3
Gedamu, L.4
-
94
-
-
0031603751
-
Diferential transactiva-tion of human metallothionein-IIa in cisplatin-resistant and-sensitive cells
-
Yang YY, Robbins PD, Lazo JS. Diferential transactiva-tion of human metallothionein-IIa in cisplatin-resistant and-sensitive cells. Oncol Res. 1998;10:85-98.
-
(1998)
Oncol Res
, vol.10
, pp. 85-98
-
-
Yang, Y.Y.1
Robbins, P.D.2
Lazo, J.S.3
-
95
-
-
0025996912
-
Cooperative interaction of an initiator-binding transcription initiation factor and the helix-loop-helix activator USF
-
Roy AL, Meisterernst M, Pognonec P, Roeder RG. Cooperative interaction of an initiator-binding transcription initiation factor and the helix-loop-helix activator USF. Nature. 1991;354:245-248
-
(1991)
Nature
, vol.354
, pp. 245-248
-
-
Roy, A.L.1
Meisterernst, M.2
Pognonec, P.3
Roeder, R.G.4
-
97
-
-
0028358324
-
Te transcription factor MTF-1 is essential for basal and heavy metal-induced metallothionein gene expression
-
Heuchel R, Radtke F, Georgiev O, Stark G, Aguet M, Schafner W. Te transcription factor MTF-1 is essential for basal and heavy metal-induced metallothionein gene expression. EMBO J. 1994;13:2870-2875
-
(1994)
EMBO J
, vol.13
, pp. 2870-2875
-
-
Heuchel, R.1
Radtke, F.2
Georgiev, O.3
Stark, G.4
Aguet, M.5
Schafner, W.6
-
98
-
-
0024222446
-
A zinc-responsive factor interacts with a metal-regulated enhancer element (MRE) of the mouse metallothionein-I gene
-
Westin G, Schafner W. A zinc-responsive factor interacts with a metal-regulated enhancer element (MRE) of the mouse metallothionein-I gene. EMBO J. 1988;7:3763-3770
-
(1988)
EMBO J
, vol.7
, pp. 3763-3770
-
-
Westin, G.1
Schafner, W.2
-
99
-
-
0027938768
-
Cloning, chromosomal mapping and characterization of the human metal-regulatory transcription factor MTF-1
-
Brugnera E, Georgiev O, Radtke F, Heuchel R, Baker E, Sutherland GR, Schafner W. Cloning, chromosomal mapping and characterization of the human metal-regulatory transcription factor MTF-1. Nucleic Acids Res. 1994;22:3167-3173
-
(1994)
Nucleic Acids Res
, vol.22
, pp. 3167-3173
-
-
Brugnera, E.1
Georgiev, O.2
Radtke, F.3
Heuchel, R.4
Baker, E.5
Sutherland, G.R.6
Schafner, W.7
-
100
-
-
0032584186
-
Control of zinc transfer between thionein, metallothionein, and zinc proteins
-
Jacob C, Maret W, Vallee BL. Control of zinc transfer between thionein, metallothionein, and zinc proteins. Proc Natl Acad Sci U S A. 1998;95:3489-3494
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 3489-3494
-
-
Jacob, C.1
Maret, W.2
Vallee, B.L.3
-
101
-
-
46149123860
-
Zinc-induced formation of a coactivator complex containing the zinc-sensing transcription factor MTF-1, p300/CBP, and Sp1
-
Li Y, Kimura T, Huyck RW, Laity JH, Andrews GK. Zinc-induced formation of a coactivator complex containing the zinc-sensing transcription factor MTF-1, p300/CBP, and Sp1. Mol Cell Biol. 2008;28:4275-4284
-
(2008)
Mol Cell Biol
, vol.28
, pp. 4275-4284
-
-
Li, Y.1
Kimura, T.2
Huyck, R.W.3
Laity, J.H.4
Andrews, G.K.5
-
102
-
-
0036805109
-
Activation of gene expression by metal-responsive signal transduction pathways
-
Adams TK, Saydam N, Steiner F, Schafner W, Freedman JH. Activation of gene expression by metal-responsive signal transduction pathways. Environ Health Perspect. 2002;110(Suppl 5):813-817
-
(2002)
Environ Health Perspect
, vol.110
, Issue.SUPPL. 5
, pp. 813-817
-
-
Adams, T.K.1
Saydam, N.2
Steiner, F.3
Schafner, W.4
Freedman, J.H.5
-
103
-
-
0031172562
-
Cadmium, gene regulation, and cellular signalling in mammalian cells
-
Beyersmann D, Hechtenberg S. Cadmium, gene regulation, and cellular signalling in mammalian cells. Toxicol Appl Pharmacol. 1997;144:247-261
-
(1997)
Toxicol Appl Pharmacol
, vol.144
, pp. 247-261
-
-
Beyersmann, D.1
Hechtenberg, S.2
-
104
-
-
0018761550
-
Dexamethasone stimulation of metallothionein synthesis in HeLa cell cultures
-
Karin M, Herschman HR. Dexamethasone stimulation of metallothionein synthesis in HeLa cell cultures. Science. 1979;204:176-177
-
(1979)
Science
, vol.204
, pp. 176-177
-
-
Karin, M.1
Herschman, H.R.2
-
105
-
-
0032804191
-
Induction of metal-lothionein by stress and its molecular mechanisms
-
Jacob ST, Ghoshal K, Sheridan JF. Induction of metal-lothionein by stress and its molecular mechanisms. Gene Expr. 1999;7:301-310
-
(1999)
Gene Expr
, vol.7
, pp. 301-310
-
-
Jacob, S.T.1
Ghoshal, K.2
Sheridan, J.F.3
-
106
-
-
0030964708
-
A pair of adjacent glucocorticoid response elements regulate expression of two mouse metallothionein genes
-
Kelly EJ, Sandgren EP, Brinster RL, Palmiter RD. A pair of adjacent glucocorticoid response elements regulate expression of two mouse metallothionein genes. Proc Natl Acad Sci U S A. 1997;94:10045-10050
-
(1997)
Proc Natl Acad Sci U S A
, vol.94
, pp. 10045-10050
-
-
Kelly, E.J.1
Sandgren, E.P.2
Brinster, R.L.3
Palmiter, R.D.4
-
107
-
-
0025024263
-
Endotoxin induction of murine metallothionein gene expression
-
De SK, McMaster MT, Andrews GK. Endotoxin induction of murine metallothionein gene expression. J Biol Chem. 1990;265:15267-15274
-
(1990)
J Biol Chem
, vol.265
, pp. 15267-15274
-
-
De Sk McMaster, M.T.1
Andrews, G.K.2
-
108
-
-
0026774224
-
Interleukin 1 regulates secretion of zinc-thymulin by human thymic epithelial cells and its action on T-lymphocyte proliferation and nuclear protein kinase C
-
Coto JA, Hadden EM, Sauro M, Zorn N, Hadden JW. Interleukin 1 regulates secretion of zinc-thymulin by human thymic epithelial cells and its action on T-lymphocyte proliferation and nuclear protein kinase C. Proc Natl Acad Sci U S A. 1992;89:7752-7756
-
(1992)
Proc Natl Acad Sci U S A
, vol.89
, pp. 7752-7756
-
-
Coto, J.A.1
Hadden, E.M.2
Sauro, M.3
Zorn, N.4
Hadden, J.W.5
-
109
-
-
0025228503
-
Interleukin 6 regulates met-allothionein gene expression and zinc metabolism in hepatocyte monolayer cultures
-
Schroeder JJ, Cousins RJ. Interleukin 6 regulates met-allothionein gene expression and zinc metabolism in hepatocyte monolayer cultures. Proc Natl Acad Sci U S A. 1990;87:3137-3141
-
(1990)
Proc Natl Acad Sci U S A
, vol.87
, pp. 3137-3141
-
-
Schroeder, J.J.1
Cousins, R.J.2
-
110
-
-
0031723210
-
Requirement for cooperative interaction of interleu-kin-6 responsive element type 2 and glucocorticoid responsive element in the synergistic activation of mouse metallothionein-I gene by interleukin-6 and glucocorticoid
-
Kasutani K, Itoh N, Kanekiyo M, Muto N, Tanaka K. Requirement for cooperative interaction of interleu-kin-6 responsive element type 2 and glucocorticoid responsive element in the synergistic activation of mouse metallothionein-I gene by interleukin-6 and glucocorticoid. Toxicol Appl Pharmacol. 1998; 151:143-151
-
(1998)
Toxicol Appl Pharmacol
, vol.151
, pp. 143-151
-
-
Kasutani, K.1
Itoh, N.2
Kanekiyo, M.3
Muto, N.4
Tanaka, K.5
-
111
-
-
33645806283
-
Role of metal-lothionein in coagulatory disturbance and systemic infammation induced by lipopolysaccharide in mice
-
Inoue K, Takano H, Shimada A, Wada E, Yanagisawa R, Sakurai M, Satoh M, Yoshikawa T. Role of metal-lothionein in coagulatory disturbance and systemic infammation induced by lipopolysaccharide in mice. FASEB J. 2006;20:533-535
-
(2006)
FASEB J
, vol.20
, pp. 533-535
-
-
Inoue, K.1
Takano, H.2
Shimada, A.3
Wada, E.4
Yanagisawa, R.5
Sakurai, M.6
Satoh, M.7
Yoshikawa, T.8
-
112
-
-
0037081794
-
Metallothionein modulates lipopolysaccharide-stimulated tumour necrosis factor expression in mouse peritoneal macrophages
-
Kanekiyo M, Itoh N, Kawasaki A, Matsuyama A, Matsuda K, Nakanishi T, Tanaka K. Metallothionein modulates lipopolysaccharide-stimulated tumour necrosis factor expression in mouse peritoneal macrophages. Biochem J. 2002;361:363-369
-
(2002)
Biochem J
, vol.361
, pp. 363-369
-
-
Kanekiyo, M.1
Itoh, N.2
Kawasaki, A.3
Matsuyama, A.4
Matsuda, K.5
Nakanishi, T.6
Tanaka, K.7
-
113
-
-
40949105551
-
Metallothionein induction by hypoxia involves cooperative interactions between metal-responsive transcription factor-1 and hypoxia-inducible transcription factor-1alpha
-
Murphy BJ, Kimura T, Sato BG, Shi Y, Andrews GK. Metallothionein induction by hypoxia involves cooperative interactions between metal-responsive transcription factor-1 and hypoxia-inducible transcription factor-1alpha. Mol Cancer Res. 2008;6:483-490
-
(2008)
Mol Cancer Res
, vol.6
, pp. 483-490
-
-
Murphy, B.J.1
Kimura, T.2
Sato, B.G.3
Shi, Y.4
Andrews, G.K.5
-
114
-
-
38449118426
-
Metallo-thionein is up-regulated under hypoxia and promotes the survival of human prostate cancer cells
-
Yamasaki M, Nomura T, Sato F, Mimata H. Metallo-thionein is up-regulated under hypoxia and promotes the survival of human prostate cancer cells. Oncol Rep. 2007;18:1145-1153
-
(2007)
Oncol Rep
, vol.18
, pp. 1145-1153
-
-
Yamasaki, M.1
Nomura, T.2
Sato, F.3
Mimata, H.4
-
115
-
-
0028593507
-
Transcriptional induction of the mouse metallothionein-I gene in hydrogen peroxide-treated Hepa cells involves a composite major late transcription factor/antioxidant response element and metal response promoter elements
-
Dalton T, Palmiter RD, Andrews GK. Transcriptional induction of the mouse metallothionein-I gene in hydrogen peroxide-treated Hepa cells involves a composite major late transcription factor/antioxidant response element and metal response promoter elements. Nucleic Acids Res. 1994;22:5016-5023
-
(1994)
Nucleic Acids Res
, vol.22
, pp. 5016-5023
-
-
Dalton, T.1
Palmiter, R.D.2
Andrews, G.K.3
-
116
-
-
0028836796
-
Cell cycle regulation of metal-lothionein in human colonic cancer cells
-
Nagel WW, Vallee BL. Cell cycle regulation of metal-lothionein in human colonic cancer cells. Proc Natl Acad Sci U S A. 1995;92:579-583
-
(1995)
Proc Natl Acad Sci U S A
, vol.92
, pp. 579-583
-
-
Nagel, W.W.1
Vallee, B.L.2
-
117
-
-
0030711622
-
Metallothionein accretion in human hepatic cells is linked to cellular proliferation
-
Studer R, Vogt CP, Cavigelli M, Hunziker PE, Kagi JH. Metallothionein accretion in human hepatic cells is linked to cellular proliferation. Biochem J. 1997;328:63-67
-
(1997)
Biochem J
, vol.328
, pp. 63-67
-
-
Studer, R.1
Vogt, C.P.2
Cavigelli, M.3
Hunziker, P.E.4
Kagi, J.H.5
-
118
-
-
0028827209
-
Metallothionein expression in placental tissue in Menkes' disease. An immunohistochemical study
-
Haerslev T, Jacobsen GK, Horn N, Damsgaard E. Metallothionein expression in placental tissue in Menkes' disease. An immunohistochemical study. APMIS. 1995;103:568-573
-
(1995)
APMIS
, vol.103
, pp. 568-573
-
-
Haerslev, T.1
Jacobsen, G.K.2
Horn, N.3
Damsgaard, E.4
-
119
-
-
27744507452
-
Metallothionein 1 is a downstream target of vascular endothelial zinc fnger 1 (VEZF1) in endothelial cells and participates in the regulation of angiogenesis
-
Miyashita H, Sato Y. Metallothionein 1 is a downstream target of vascular endothelial zinc fnger 1 (VEZF1) in endothelial cells and participates in the regulation of angiogenesis. Endothelium. 2005;12:163-170
-
(2005)
Endothelium
, vol.12
, pp. 163-170
-
-
Miyashita, H.1
Sato, Y.2
-
120
-
-
0027426917
-
Heterodimerization of the transcription factors E2F-1 and DP-1 leads to cooperative trans-activation
-
Helin K, Wu CL, Fattaey AR, Lees JA, Dynlacht BD, Ngwu C, Harlow E. Heterodimerization of the transcription factors E2F-1 and DP-1 leads to cooperative trans-activation. Genes Dev. 1993;7:1850-1861
-
(1993)
Genes Dev
, vol.7
, pp. 1850-1861
-
-
Helin, K.1
Wu, C.L.2
Fattaey, A.R.3
Lees, J.A.4
Dynlacht, B.D.5
Ngwu, C.6
Harlow, E.7
-
121
-
-
0039136305
-
Cadmium induces conformational modifcations of wild-type p53 and suppresses p53 response to DNA damage in cultured cells
-
Meplan C, Mann K, Hainaut P. Cadmium induces conformational modifcations of wild-type p53 and suppresses p53 response to DNA damage in cultured cells. J Biol Chem. 1999;274:31663-31670
-
(1999)
J Biol Chem
, vol.274
, pp. 31663-31670
-
-
Meplan, C.1
Mann, K.2
Hainaut, P.3
-
122
-
-
0023651331
-
Positive and negative regulation of transcription in vitro: Enhancer-binding protein AP-2 is inhibited by SV40 T antigen
-
Mitchell PJ, Wang C, Tjian R. Positive and negative regulation of transcription in vitro: enhancer-binding protein AP-2 is inhibited by SV40 T antigen. Cell. 1987;50:847-861
-
(1987)
Cell
, vol.50
, pp. 847-861
-
-
Mitchell, P.J.1
Wang, C.2
Tjian, R.3
-
123
-
-
0021447006
-
Te ontogeny of expression of murine metallothionein: Comparison with the alpha-fetoprotein gene
-
Andrews GK, Adamson ED, Gedamu L. Te ontogeny of expression of murine metallothionein: comparison with the alpha-fetoprotein gene. Dev Biol. 1984;103:294-303.
-
(1984)
Dev Biol
, vol.103
, pp. 294-303
-
-
Andrews, G.K.1
Adamson, E.D.2
Gedamu, L.3
-
124
-
-
0035283151
-
Te transcription factors MTF-1 and USF1 cooperate to regulate mouse metallothionein-I expression in response to the essential metal zinc in visceral endoderm cells during early development
-
Andrews GK, Lee DK, Ravindra R, Lichtlen P, Sirito M, Sawadogo M, Schafner W. Te transcription factors MTF-1 and USF1 cooperate to regulate mouse metallothionein-I expression in response to the essential metal zinc in visceral endoderm cells during early development. EMBO J. 2001;20:1114-1122
-
(2001)
EMBO J
, vol.20
, pp. 1114-1122
-
-
Andrews, G.K.1
Lee, D.K.2
Ravindra, R.3
Lichtlen, P.4
Sirito, M.5
Sawadogo, M.6
Schafner, W.7
-
125
-
-
0344256726
-
-
Sheng G, dos Reis M, Stern CD. Churchill, a zinc fnger transcriptional activator, regulates the transition between gastrulation and neurulation. Cell. 2003;115:603-613
-
(2003)
Dos Reis M, Stern CD. Churchill, A Zinc Fnger Transcriptional Activator, Regulates the Transition between Gastrulation and Neurulation. Cell
, vol.115
, pp. 603-613
-
-
Sheng, G.1
-
126
-
-
0024437754
-
Nuclear factor ETF specifcally stimulates transcription from promoters without a TATA box
-
Kageyama R, Merlino GT, Pastan I. Nuclear factor ETF specifcally stimulates transcription from promoters without a TATA box. J Biol Chem. 1989;264:15508-15514
-
(1989)
J Biol Chem
, vol.264
, pp. 15508-15514
-
-
Kageyama, R.1
Merlino, G.T.2
Pastan, I.3
-
128
-
-
0034963936
-
Downregulation of constitutive and heavy metal-induced metallothionein-I expression by nuclear factor i
-
Majumder S, Ghoshal K, Gronostajski RM, Jacob ST. Downregulation of constitutive and heavy metal-induced metallothionein-I expression by nuclear factor I. Gene Expr. 2001;9:203-215
-
(2001)
Gene Expr
, vol.9
, pp. 203-215
-
-
Majumder, S.1
Ghoshal, K.2
Gronostajski, R.M.3
Jacob, S.T.4
-
129
-
-
0027770756
-
Identifcation of a sequence within the mouse metallothionein-I gene promoter mediating its basal transcription and of a protein interacting with this element
-
Datta PK, Jacob ST. Identifcation of a sequence within the mouse metallothionein-I gene promoter mediating its basal transcription and of a protein interacting with this element. Cell Mol Biol Res. 1993;39:439-449
-
(1993)
Cell Mol Biol Res
, vol.39
, pp. 439-449
-
-
Datta, P.K.1
Jacob, S.T.2
-
130
-
-
0032940101
-
Trans repression of the human metallothionein IIA gene promoter by PZ120, a novel 120-kilodalton zinc fnger protein
-
Tang CM, Westling J, Seto E. trans repression of the human metallothionein IIA gene promoter by PZ120, a novel 120-kilodalton zinc fnger protein. Mol Cell Biol. 1999;19:680-689
-
(1999)
Mol Cell Biol
, vol.19
, pp. 680-689
-
-
Tang, C.M.1
Westling, J.2
Seto, E.3
-
131
-
-
63849202675
-
Metal transcription factor-1 is involved in hypoxia-dependent regulation of placenta growth factor in trophoblast-derived cells
-
Nishimoto F, Sakata M, Minekawa R, Okamoto Y, Miyake A, Isobe A, Yamamoto T, Takeda T, Ishida E, Sawada K, Morishige K, Kimura T. Metal transcription factor-1 is involved in hypoxia-dependent regulation of placenta growth factor in trophoblast-derived cells. Endocrinology. 2009;150:1801-1808
-
(2009)
Endocrinology
, vol.150
, pp. 1801-1808
-
-
Nishimoto, F.1
Sakata, M.2
Minekawa, R.3
Okamoto, Y.4
Miyake, A.5
Isobe, A.6
Yamamoto, T.7
Takeda, T.8
Ishida, E.9
Sawada, K.10
Morishige, K.11
Kimura, T.12
-
132
-
-
34047263219
-
Metallothionein expression is suppressed in primary human hepatocellular carcinomas and is mediated through inactivation of CCAAT/ enhancer binding protein alpha by phosphati-dylinositol 3-kinase signaling cascade
-
Datta J, Majumder S, Kutay H, Motiwala T, Frankel W, Costa R, Cha HC, MacDougald OA, Jacob ST, Ghoshal K. Metallothionein expression is suppressed in primary human hepatocellular carcinomas and is mediated through inactivation of CCAAT/ enhancer binding protein alpha by phosphati-dylinositol 3-kinase signaling cascade. Cancer Res. 2007;67:2736-2746
-
(2007)
Cancer Res
, vol.67
, pp. 2736-2746
-
-
Datta, J.1
Majumder, S.2
Kutay, H.3
Motiwala, T.4
Frankel, W.5
Costa, R.6
Cha, H.C.7
MacDougald, O.A.8
Jacob, S.T.9
Ghoshal, K.10
-
133
-
-
0022729556
-
Structure and tissue-specifc expression of the human metallothionein IB gene
-
Heguy A, West A, Richards RI, Karin M. Structure and tissue-specifc expression of the human metallothionein IB gene. Mol Cell Biol. 1986;6:2149-2157
-
(1986)
Mol Cell Biol
, vol.6
, pp. 2149-2157
-
-
Heguy, A.1
West, A.2
Richards, R.I.3
Karin, M.4
-
134
-
-
29244447735
-
Metallothionien 3 expression is frequently down-regulated in oesophageal squamous cell carcinoma by DNA methylation
-
Smith E, Drew PA, Tian ZQ, De Young NJ, Liu JF, Mayne GC, Ruszkiewicz AR, Watson DI, Jamieson GG. Metallothionien 3 expression is frequently down-regulated in oesophageal squamous cell carcinoma by DNA methylation. Mol Cancer. 2005;4:42.
-
(2005)
Mol Cancer
, vol.4
, pp. 42
-
-
Smith, E.1
Drew, P.A.2
Tian, Z.Q.3
De Young, N.J.4
Liu, J.F.5
Mayne, G.C.6
Ruszkiewicz, A.R.7
Watson, D.I.8
Jamieson, G.G.9
-
135
-
-
0037275807
-
Hypermethylation of metallothionein-3 CpG island in gastric carcinoma
-
Deng D, El-Rifai W, Ji J, Zhu B, Trampont P, Li J, Smith MF, Powel SM. Hypermethylation of metallothionein-3 CpG island in gastric carcinoma. Carcinogenesis. 2003;24:25-29
-
(2003)
Carcinogenesis
, vol.24
, pp. 25-29
-
-
Deng, D.1
El-Rifai, W.2
Ji, J.3
Zhu, B.4
Trampont, P.5
Li, J.6
Smith, M.F.7
Powel, S.M.8
-
136
-
-
33645690762
-
Epigenetic regulation of metallothionein-i gene expression: Diferential regulation of methylated and unmethylated promoters by DNA methyltransferases and methyl CpG binding proteins
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Majumder S, Kutay H, Datta J, Summers D, Jacob ST, Ghoshal K. Epigenetic regulation of metallothionein-i gene expression: diferential regulation of methylated and unmethylated promoters by DNA methyltransferases and methyl CpG binding proteins. J Cell Biochem. 2006;97:1300-1316
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(2006)
J Cell Biochem
, vol.97
, pp. 1300-1316
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Majumder, S.1
Kutay, H.2
Datta, J.3
Summers, D.4
Jacob, S.T.5
Ghoshal, K.6
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